Produce maximum likelihood estimates of common accuracy statistics for multiple measurement methods when a gold standard is not available. An R implementation of the expectation maximization algorithms described in Zhou et al. (2011) <doi:10.1002/9780470906514> with additional functions for creating simulated data and visualizing results. Supports binary, ordinal, and continuous measurement methods.

Bayesian (and some likelihoodist) functions as alternatives to hypothesis-testing functions in R base using a user interface patterned after those of R's hypothesis testing functions. See McElreath (2016, ISBN: 978-1-4822-5344-3), Gelman and Hill (2007, ISBN: 0-521-68689-X) (new edition in preparation) and Albert (2009, ISBN: 978-0-387-71384-7) for good introductions to Bayesian analysis and Pawitan (2002, ISBN: 0-19-850765-8) for the Likelihood approach. The functions in the package also make extensive use of graphical displays for data exploration and model comparison.

EQ-5D is a popular health related quality of life instrument used in the clinical and economic evaluation of health care. Developed by the EuroQol group <https://euroqol.org/>, the instrument consists of two components: health state description and evaluation. For the description component a subject self-rates their health in terms of five dimensions; mobility, self-care, usual activities, pain/discomfort, and anxiety/depression using either a three-level (EQ-5D-3L, <https://euroqol.org/information-and-support/euroqol-instruments/eq-5d-3l/>) or a five-level (EQ-5D-5L, <https://euroqol.org/information-and-support/euroqol-instruments/eq-5d-5l/>) scale. Frequently the scores on these five dimensions are converted to a single utility index using country specific value sets, which can be used in the clinical and economic evaluation of health care as well as in population health surveys. The eq5d package provides methods to calculate index scores from a subject's dimension scores. 32 TTO and 11 VAS EQ-5D-3L value sets including those for countries in Szende et al (2007) <doi:10.1007/1-4020-5511-0> and Szende et al (2014) <doi:10.1007/978-94-007-7596-1>, 48 EQ-5D-5L EQ-VT value sets, the EQ-5D-5L crosswalk value sets developed by van Hout et al. (2012) <doi:10.1016/j.jval.2012.02.008>, the crosswalk value sets for Bermuda, Jordan and Russia and the van Hout (2021) reverse crosswalk value sets. 11 EQ-5D-Y3L value sets are also included as are the NICE DSU age-sex based EQ-5D-3L to EQ-5D-5L and EQ-5D-5L to EQ-5D-3L mappings. Methods are also included for the analysis of EQ-5D profiles, including those from the book "Methods for Analyzing and Reporting EQ-5D data" by Devlin et al. (2020) <doi:10.1007/978-3-030-47622-9>. Additionally a shiny web tool is included to enable the calculation, visualisation and automated statistical analysis of EQ-5D data via a web browser using EQ-5D dimension scores stored in CSV or Excel files.

Alluvial plots are similar to sankey diagrams and visualise categorical data over multiple dimensions as flows. (Rosvall M, Bergstrom CT (2010) Mapping Change in Large Networks. PLoS ONE 5(1): e8694. <doi:10.1371/journal.pone.0008694> Their graphical grammar however is a bit more complex then that of a regular x/y plots. The ggalluvial package made a great job of translating that grammar into ggplot2 syntax and gives you many options to tweak the appearance of an alluvial plot, however there still remains a multi-layered complexity that makes it difficult to use ggalluvial for explorative data analysis. easyalluvial provides a simple interface to this package that allows you to produce a decent alluvial plot from any dataframe in either long or wide format from a single line of code while also handling continuous data. It is meant to allow a quick visualisation of entire dataframes with a focus on different colouring options that can make alluvial plots a great tool for data exploration.

For multiscale analysis, this package carries out ensemble patch transform, its visualization and multiscale decomposition. The detailed procedure is described in Kim et al. (2020), and Oh and Kim (2020). D. Kim, G. Choi, H.-S. Oh, Ensemble patch transformation: a flexible framework for decomposition and filtering of signal, EURASIP Journal on Advances in Signal Processing 30 (2020) 1-27 <doi:10.1186/s13634-020-00690-7>. H.-S. Oh, D. Kim, Image decomposition by bidimensional ensemble patch transform, Pattern Recognition Letters 135 (2020) 173-179 <doi:10.1016/j.patrec.2020.03.029>.

This data management package provides some helper classes for publicly available data sources (HMD, DESTATIS) in Demography. Similar to ideas developed in the Bioconductor project <https://bioconductor.org> we strive to encapsulate data in easy to use S4 objects. If original data is provided in a text file, the resulting S4 object contains all information from that text file. But the information is somehow structured (header, footer, etc). Further the classes provide methods to make a subset for selected calendar years or selected regions. The resulting subset objects still contain the original header and footer information.

Descriptive Statistics is essential for publishing articles. This package can perform descriptive statistics according to different data types. If the data is a continuous variable, the mean and standard deviation or median and quartiles are automatically output; if the data is a categorical variable, the number and percentage are automatically output. In addition, if you enter two variables in this package, the two variables will be described and their relationships will be tested automatically according to their data types. For example, if one of the two input variables is a categorical variable, another variable will be described hierarchically based on the categorical variable and the statistical differences between different groups will be compared using appropriate statistical methods. And for groups of more than two, the post hoc test will be applied. For more information on the methods we used, please see the following references: Libiseller, C. and Grimvall, A. (2002) <doi:10.1002/env.507>, Patefield, W. M. (1981) <doi:10.2307/2346669>, Hope, A. C. A. (1968) <doi:10.1111/J.2517-6161.1968.TB00759.X>, Mehta, C. R. and Patel, N. R. (1983) <doi:10.1080/01621459.1983.10477989>, Mehta, C. R. and Patel, N. R. (1986) <doi:10.1145/6497.214326>, Clarkson, D. B., Fan, Y. and Joe, H. (1993) <doi:10.1145/168173.168412>, Cochran, W. G. (1954) <doi:10.2307/3001616>, Armitage, P. (1955) <doi:10.2307/3001775>, Szabo, A. (2016) <doi:10.1080/00031305.2017.1407823>, David, F. B. (1972) <doi:10.1080/01621459.1972.10481279>, Joanes, D. N. and Gill, C. A. (1998) <doi:10.1111/1467-9884.00122>, Dunn, O. J. (1964) <doi:10.1080/00401706.1964.10490181>, Copenhaver, M. D. and Holland, B. S. (1988) <doi:10.1080/00949658808811082>, Chambers, J. M., Freeny, A. and Heiberger, R. M. (1992) <doi:10.1201/9780203738535-5>, Shaffer, J. P. (1995) <doi:10.1146/annurev.ps.46.020195.003021>, Myles, H. and Douglas, A. W. (1973) <doi:10.2307/2063815>, Rahman, M. and Tiwari, R. (2012) <doi:10.4236/health.2012.410139>, Thode, H. J. (2002) <doi:10.1201/9780203910894>, Jonckheere, A. R. (1954) <doi:10.2307/2333011>, Terpstra, T. J. (1952) <doi:10.1016/S1385-7258(52)50043-X>.

Access data related to the European union from GISCO <https://ec.europa.eu/eurostat/web/gisco>, the Geographic Information System of the European Commission, via its rest API at <https://gisco-services.ec.europa.eu>. This package tries to make it easier to get these data into R.

Researchers often use the bootstrap to understand a sample drawn from a population with unknown distribution. The exact bootstrap method is a practical tool for exploring the distribution of small sample size data. For a sample of size n, the exact bootstrap method generates the entire space of n to the power of n resamples and calculates all realizations of the selected statistic. The exactamente package includes functions for implementing two bootstrap methods, the exact bootstrap and the regular bootstrap. The exact_bootstrap() function applies the exact bootstrap method following methodologies outlined in Kisielinska (2013) <doi:10.1007/s00180-012-0350-0>. The regular_bootstrap() function offers a more traditional bootstrap approach, where users can determine the number of resamples. The e_vs_r() function allows users to directly compare results from these bootstrap methods. To augment user experience, exactamente includes the function exactamente_app() which launches an interactive shiny web application. This application facilitates exploration and comparison of the bootstrap methods, providing options for modifying various parameters and visualizing results.

This package provides tools to fit Mixture Cure Rate models via the Expectation-Maximization (EM) algorithm, allowing for flexible link functions in the cure component and various survival distributions in the latency part. The package supports user-specified link functions, includes methods for parameter estimation and model diagnostics, and provides residual analysis tailored for cure models. The classical theory methods used are described in Berkson, J. and Gage, R. P. (1952) <doi:10.2307/2281318>, Dempster, A. P., Laird, N. M. and Rubin, D. B. (1977) <https://www.jstor.org/stable/2984875>, Bazán, J., Torres-Avilés, F., Suzuki, A. and Louzada, F. (2017)<doi:10.1002/asmb.2215>.

Forecasting univariate time series with different decomposition based Extreme Learning Machine models. For method details see Yu L, Wang S, Lai KK (2008). <doi:10.1016/j.eneco.2008.05.003>, Parida M, Behera MK, Nayak N (2018). <doi:10.1109/ICSESP.2018.8376723>.

Implementation of uniformly most powerful invariant equivalence tests for one- and two-sample problems (paired and unpaired) as described in Wellek (2010, ISBN:978-1-4398-0818-4). Also one-sided alternatives (non-inferiority and non-superiority tests) are supported. Basically a variant of a t-test with (relaxed) null and alternative hypotheses exchanged.

Create causal models for use in epidemiological studies, including sufficient-component cause models as introduced by Rothman (1976) <doi:10.1093/oxfordjournals.aje.a112335>.

Fast and very memory-efficient calculation of isotope patterns, subsequent convolution to theoretical envelopes (profiles) plus valley detection and centroidization or intensoid calculation. Batch processing, resolution interpolation, wrapper, adduct calculations and molecular formula parsing. Loos, M., Gerber, C., Corona, F., Hollender, J., Singer, H. (2015) <doi:10.1021/acs.analchem.5b00941>.

This package provides functions for eleven procedures for determining the number of factors, including functions for parallel analysis and the minimum average partial test. There are also functions for conducting principal components analysis, principal axis factor analysis, maximum likelihood factor analysis, image factor analysis, and extension factor analysis, all of which can take raw data or correlation matrices as input and with options for conducting the analyses using Pearson correlations, Kendall correlations, Spearman correlations, gamma correlations, or polychoric correlations. Varimax rotation, promax rotation, and Procrustes rotations can be performed. Additional functions focus on the factorability of a correlation matrix, the congruences between factors from different datasets, the assessment of local independence, the assessment of factor solution complexity, internal consistency, and for correcting Pearson correlation coefficients for attenuation due to unreliability. Auerswald & Moshagen (2019, ISSN:1939-1463); Field, Miles, & Field (2012, ISBN:978-1-4462-0045-2); Mulaik (2010, ISBN:978-1-4200-9981-2); O'Connor (2000, <doi:10.3758/bf03200807>); O'Connor (2001, ISSN:0146-6216).

This package provides a function for distribution free control chart based on the change point model, for multivariate statistical process control. The main constituent of the chart is the energy test that focuses on the discrepancy between empirical characteristic functions of two random vectors. This new control chart highlights in three aspects. Firstly, it is distribution free, requiring no knowledge of the random processes. Secondly, this control chart can monitor mean and variance simultaneously. Thirdly it is devised for multivariate time series which is more practical in real data application. Fourthly, it is designed for online detection (Phase II), which is central for real time surveillance of stream data. For more information please refer to O. Okhrin and Y.F. Xu (2017) <https://github.com/YafeiXu/working_paper/raw/master/CPM102.pdf>.

Analysis of experimental results and automatic report generation in both interactive HTML and LaTeX. This package ships with a rich interface for data modeling and built in functions for the rapid application of statistical tests and generation of common plots and tables with publish-ready quality.

Univariate and multivariate methods for compositional data analysis, based on logratios. The package implements the approach in the book Compositional Data Analysis in Practice by Michael Greenacre (2018), where accent is given to simple pairwise logratios. Selection can be made of logratios that account for a maximum percentage of logratio variance. Various multivariate analyses of logratios are included in the package.

Various Expectation-Maximization (EM) algorithms are implemented for item response theory (IRT) models. The package includes IRT models for binary and ordinal responses, along with dynamic and hierarchical IRT models with binary responses. The latter two models are fitted using variational EM. The package also includes variational network and text scaling models. The algorithms are described in Imai, Lo, and Olmsted (2016) <DOI:10.1017/S000305541600037X>.

Extends the Changes-in-Changes model a la Athey and Imbens (2006) <doi:10.1111/j.1468-0262.2006.00668.x> to multiple cohorts and time periods, which generalizes difference-in-differences estimation techniques to the entire distribution. Computes quantile treatment effects for every possible two-by-two combination in ecic(). Then, aggregating all bootstrap runs adds the standard errors in summary_ecic(). Results can be plotted with plot_ecic() aggregated over all cohort-group combinations or in an event-study style for either individual periods or individual quantiles.

Constructs a shiny app function with interactive displays for summary and analysis of variance regression tables, and parallel coordinate plots of data and residuals.

This package provides functions to test for gene x gene interactions in a bi-parental population of inbred lines. The data are fitted with the mixed linear model described in Rio et al. (2022) <doi:10.1101/2022.12.18.520958>, that accounts for gene x gene interactions at both the fixed effect and variance levels. The package also provides graphical tools to display the gene x gene interaction trend at the mean level and the variance component analysis.

Import SPSS data, handle and change SPSS meta data, store and access large hierarchical data in SQLite data bases.

This is a package for exact Confidence Intervals for the difference between two independent or dependent proportions.