Maximum likelihood estimation of nonlinear mixed effects models of epidemic growth using Template Model Builder ('TMB'). Enables joint estimation for collections of disease incidence time series, including time series that describe multiple epidemic waves. Supports a set of widely used phenomenological models: exponential, logistic, Richards (generalized logistic), subexponential, and Gompertz. Provides methods for interrogating model objects and several auxiliary functions, including one for computing basic reproduction numbers from fitted values of the initial exponential growth rate. Preliminary versions of this software were applied in Ma et al. (2014) <doi:10.1007/s11538-013-9918-2> and in Earn et al. (2020) <doi:10.1073/pnas.2004904117>.

Analysis of experimental results and automatic report generation in both interactive HTML and LaTeX. This package ships with a rich interface for data modeling and built in functions for the rapid application of statistical tests and generation of common plots and tables with publish-ready quality.

Evaluates the empirical characteristic function of univariate and multivariate samples. This package uses RcppArmadillo for fast evaluation. It is also possible to export the code to be used in other packages at C++ level.

Some EM-type algorithms to estimate parameters for the well-known Heckman selection model are provided in the package. Such algorithms are as follow: ECM(Expectation/Conditional Maximization), ECM(NR)(the Newton-Raphson method is adapted to the ECM) and ECME(Expectation/Conditional Maximization Either). Since the algorithms are based on the EM algorithm, they also have EMâ s main advantages, namely, stability and ease of implementation. Further details and explanations of the algorithms can be found in Zhao et al. (2020) <doi: 10.1016/j.csda.2020.106930>.

Three semi-parametric methods for detection of outliers in environmental data based on kernel regression and subsequent analysis of smoothing residuals. The first method (Campulova, Michalek, Mikuska and Bokal (2018) <DOI: 10.1002/cem.2997>) analyzes the residuals using changepoint analysis, the second method is based on control charts (Campulova, Veselik and Michalek (2017) <DOI: 10.1016/j.apr.2017.01.004>) and the third method (Holesovsky, Campulova and Michalek (2018) <DOI: 10.1016/j.apr.2017.06.005>) analyzes the residuals using extreme value theory (Holesovsky, Campulova and Michalek (2018) <DOI: 10.1016/j.apr.2017.06.005>).

Compute a cyclist's Eddington number, including efficiently computing cumulative E over a vector. A cyclist's Eddington number <https://en.wikipedia.org/wiki/Arthur_Eddington#Eddington_number_for_cycling> is the maximum number satisfying the condition such that a cyclist has ridden E miles or greater on E distinct days. The algorithm in this package is an improvement over the conventional approach because both summary statistics and cumulative statistics can be computed in linear time, since it does not require initial sorting of the data. These functions may also be used for computing h-indices for authors, a metric described by Hirsch (2005) <doi:10.1073/pnas.0507655102>. Both are specific applications of computing the side length of a Durfee square <https://en.wikipedia.org/wiki/Durfee_square>.

This package provides various statistical methods for evaluating heterogeneous treatment effects (HTE) in randomized experiments. The package includes tools to estimate uniform confidence bands for estimation of the group average treatment effect sorted by generic machine learning algorithms (GATES). It also provides the tools to identify a subgroup of individuals who are likely to benefit from a treatment the most "exceptional responders" or those who are harmed by it. Detailed reference in Imai and Li (2023) <doi:10.48550/arXiv.2310.07973>.

This package performs likelihood-based extreme value inferences with adjustment for the presence of missing values based on Simpson and Northrop (2026). A Generalised Extreme Value distribution is fitted to block maxima using maximum likelihood estimation, with the location and scale parameters reflecting the numbers of non-missing raw values in each block. A Bayesian version is also provided. For the purposes of comparison, there are options to make no adjustment for missing values or to discard any block maximum for which greater than a percentage of the underlying raw values are missing. Example datasets containing missing values are provided.

Various Expectation-Maximization (EM) algorithms are implemented for item response theory (IRT) models. The package includes IRT models for binary and ordinal responses, along with dynamic and hierarchical IRT models with binary responses. The latter two models are fitted using variational EM. The package also includes variational network and text scaling models. The algorithms are described in Imai, Lo, and Olmsted (2016) <DOI:10.1017/S000305541600037X>.

Density, distribution function, quantile function and random generation for the Kumaraswamy Complementary Weibull Geometric (Kw-CWG) lifetime probability distribution proposed in Afify, A.Z. et al (2017) <doi:10.1214/16-BJPS322>.

This package creates simple or stacked epidemic curves for hourly, daily, weekly or monthly outcome data.

Extends the ergm.multi packages from the Statnet suite to fit (temporal) exponential-family random graph models for signed networks. The framework models positive and negative ties as interdependent, which allows estimation and testing of structural balance theory. The package also includes options for descriptive summaries, visualization, and simulation of signed networks. See Krivitsky, Koehly, and Marcum (2020) <doi:10.1007/s11336-020-09720-7> and Fritz, C., Mehrl, M., Thurner, P. W., & Kauermann, G. (2025) <doi:10.1017/pan.2024.21>.

Implementation of uniformly most powerful invariant equivalence tests for one- and two-sample problems (paired and unpaired) as described in Wellek (2010, ISBN:978-1-4398-0818-4). Also one-sided alternatives (non-inferiority and non-superiority tests) are supported. Basically a variant of a t-test with (relaxed) null and alternative hypotheses exchanged.

Tests the equality of two covariance matrices, used in paper "Two sample tests for high dimensional covariance matrices." Li and Chen (2012) <arXiv:1206.0917>.

This package provides tools to analyze the embryo growth and the sexualisation thermal reaction norms. See <doi:10.7717/peerj.8451> for tsd functions; see <doi:10.1016/j.jtherbio.2014.08.005> for thermal reaction norm of embryo growth.

Please note: active development has moved to packages validate and errorlocate'. Facilitates reading and manipulating (multivariate) data restrictions (edit rules) on numerical and categorical data. Rules can be defined with common R syntax and parsed to an internal (matrix-like format). Rules can be manipulated with variable elimination and value substitution methods, allowing for feasibility checks and more. Data can be tested against the rules and erroneous fields can be found based on Fellegi and Holt's generalized principle. Rules dependencies can be visualized with using the igraph package.

Initially designed to distribute code for estimating the Gaussian graphical model with Lasso regularization, also known as the graphical lasso (glasso), using an Expectation-Maximization (EM) algorithm based on work by Städler and Bühlmann (2012) <doi:10.1007/s11222-010-9219-7>. As a byproduct, code for estimating means and covariances (or the precision matrix) under a multivariate normal (Gaussian) distribution is also available.

This package implements the conditional estimation procedure of Lee, Sun, Sun and Taylor (2016) <doi:10.1214/15-AOS1371>. This procedure allows hypothesis testing on the mean of a normal random vector subject to linear constraints.

This package contains logic for computing sparse principal components via the EESPCA method, which is based on an approximation of the eigenvector/eigenvalue identity. Includes logic to support execution of the TPower and rifle sparse PCA methods, as well as logic to estimate the sparsity parameters used by EESPCA, TPower and rifle via cross-validation to minimize the out-of-sample reconstruction error. H. Robert Frost (2021) <doi:10.1080/10618600.2021.1987254>.

Collection of functions related to benchmark with prediction models for data analysis and editing of clinical and epidemiological data.

This package contains elementary tools for analysis of common epidemiological problems, ranging from sample size estimation, through 2x2 contingency table analysis and basic measures of agreement (kappa, sensitivity/specificity). Appropriate print and summary statements are also written to facilitate interpretation wherever possible. Source code is commented throughout to facilitate modification. The target audience includes advanced undergraduate and graduate students in epidemiology or biostatistics courses, and clinical researchers.

The EconDataverse is a universe of open-source packages to work seamlessly with economic data. This package is designed to make it easy to download selected datasets that are preprocessed by EconDataverse packages and publicly hosted on Hugging Face'. Learn more about the EconDataverse at <https://www.econdataverse.org>.

It contains functions for dose calculation for different routes, fitting data to probability distributions, random number generation (Monte Carlo simulation) and calculation of systemic and carcinogenic risks. For more information see the publication: Barrio-Parra et al. (2019) "Human-health probabilistic risk assessment: the role of exposure factors in an urban garden scenario" <doi:10.1016/j.landurbplan.2019.02.005>.

An implementation of the ESS algorithm following Amol Deshpande, Minos Garofalakis, Michael I Jordan (2013) <doi:10.48550/arXiv.1301.2267>. The ESS algorithm is used for model selection in decomposable graphical models.