This package provides tools to automate external pharmacokinetic model evaluation workflows, including Bayesian forecasting, predictive performance metrics, diagnostic plotting, and automated reporting.

Fully robust versions of the elastic net estimator are introduced for linear and binary and multinomial regression, in particular high dimensional data. The algorithm searches for outlier free subsets on which the classical elastic net estimators can be applied. A reweighting step is added to improve the statistical efficiency of the proposed estimators. Selecting appropriate tuning parameters for elastic net penalties are done via cross-validation.

Analysis of items and persons in data. To identify and remove person misfit in polytomous item-response data using either mokken or a graded response model (GRM, via mirt'). Provides automatic thresholds, visual diagnostics (2D/3D), and export utilities. Methods build on Mokken scaling as in Mokken (1971, ISBN:9789027968821) and on the graded response model of Samejima (1969) <doi:10.1007/BF03372160>.

This package contains a collection of examples of evidence factors in observational studies from the book Replication and Evidence Factors in Observational Studies by Paul R. Rosenbaum (2021) <doi:10.1201/9781003039648>.

Using variational techniques we address some epidemiological problems as the incidence curve decomposition by inverting the renewal equation as described in Alvarez et al. (2021) <doi:10.1073/pnas.2105112118> and Alvarez et al. (2022) <doi:10.3390/biology11040540> or the estimation of the functional relationship between epidemiological indicators. We also propose a learning method for the short time forecast of the trend incidence curve as described in Morel et al. (2022) <doi:10.1101/2022.11.05.22281904>.

This package provides tools for importing, analyzing and visualizing ego-centered network data. Supports several data formats, including the export formats of EgoNet', EgoWeb 2.0 and openeddi'. An interactive (shiny) app for the intuitive visualization of ego-centered networks is provided. Also included are procedures for creating and visualizing Clustered Graphs (Lerner 2008 <DOI:10.1109/PACIFICVIS.2008.4475458>).

The Explainable Ensemble Trees e2tree approach has been proposed by Aria et al. (2024) <doi:10.1007/s00180-022-01312-6>. It aims to explain and interpret decision tree ensemble models using a single tree-like structure. e2tree is a new way of explaining an ensemble tree trained through randomForest or xgboost packages.

This package provides a user friendly, easy to understand way of doing event history regression for marginal estimands of interest, including the cumulative incidence and the restricted mean survival, using the pseudo observation framework for estimation. For a review of the methodology, see Andersen and Pohar Perme (2010) <doi:10.1177/0962280209105020> or Sachs and Gabriel (2022) <doi:10.18637/jss.v102.i09>. The interface uses the well known formulation of a generalized linear model and allows for features including plotting of residuals, the use of sampling weights, and corrected variance estimation.

Fits dose-response models using an evolutionary algorithm to estimate the model parameters. The procedure currently can fit 3-parameter, 4-parameter, and 5-parameter log-logistic models as well as exponential models. Functions are also provided to plot, make predictions, and calculate confidence intervals for the resulting models. For details see "Nonlinear Dose-response Modeling of High-Throughput Screening Data Using an Evolutionary Algorithm", Ma, J., Bair, E., Motsinger-Reif, A.; Dose-Response 18(2):1559325820926734 (2020) <doi:10.1177/1559325820926734>.

Shiny interfaces and graphical functions for multivariate analysis results exploration.

Presents a statistical method that uses a recursive algorithm for signal extraction. The method handles a non-parametric estimation for the correlation of the errors. See "Krivobokova", "Serra", "Rosales" and "Klockmann" (2021) <arXiv:1812.06948> for details.

Shiny application for eliciting Bayesian prior distributions using large language models (LLMs). Supports multiple LLM experts, linear opinion pooling, and the Delphi method for iterative consensus. For more details see J. R. Falconer et al. (2022) <doi:10.1287/deca.2022.0451> and D. Selby et al. (2025) <doi:10.1002/sta4.70054>.

Estimation of production functions by the Olley-Pakes, Levinsohn-Petrin and Wooldridge methodologies. The package aims to reproduce the results obtained with the Stata's user written opreg <http://www.stata-journal.com/article.html?article=st0145> and levpet <http://www.stata-journal.com/article.html?article=st0060> commands. The first was originally proposed by Olley, G.S. and Pakes, A. (1996) <doi:10.2307/2171831>. The second by Levinsohn, J. and Petrin, A. (2003) <doi:10.1111/1467-937X.00246>. And the third by Wooldridge (2009) <doi:10.1016/j.econlet.2009.04.026>.

This package contains additional miscellaneous steps for the recipes package. These steps are useful, but doesn't have a good home in other recipes packages or its extensions.

This package provides a number of utility function for exploratory factor analysis are included in this package. In particular, it computes standard errors for parameter estimates and factor correlations under a variety of conditions.

Download and process public education data from INEP (Instituto Nacional de Estudos e Pesquisas Educacionais Anà sio Teixeira). Provides functions to access microdata from the School Census (Censo Escolar), ENEM (Exame Nacional do Ensino Médio), SAEB (Sistema de Avaliação da Educação Básica), Higher Education Census (Censo da Educação Superior), ENADE (Exame Nacional de Desempenho dos Estudantes), ENCCEJA (Exame Nacional para Certificação de Competências de Jovens e Adultos), IDD (Indicador de Diferença entre os Desempenhos Observado e Esperado), CPC (Conceito Preliminar de Curso), IGC (à ndice Geral de Cursos), CAPES graduate education data, FUNDEB (Fundo de Manutencao e Desenvolvimento da Educacao Basica), IDEB (à ndice de Desenvolvimento da Educação Básica), and other educational datasets. Returns data in tidy format ready for analysis. Data source: INEP Open Data Portal <https://www.gov.br/inep/pt-br/acesso-a-informacao/dados-abertos>.

Estimates extinction risk from population time series under a drifted Wiener process using MLE and observation-error-and-autocovariance-robust estimators, with confidence intervals based on the w-z method.

This package provides various statistical methods for evaluating heterogeneous treatment effects (HTE) in randomized experiments. The package includes tools to estimate uniform confidence bands for estimation of the group average treatment effect sorted by generic machine learning algorithms (GATES). It also provides the tools to identify a subgroup of individuals who are likely to benefit from a treatment the most "exceptional responders" or those who are harmed by it. Detailed reference in Imai and Li (2023) <doi:10.48550/arXiv.2310.07973>.

Fits Leroux model in spectral domain to estimate causal spatial effect as detailed in Guan, Y; Page, G.L.; Reich, B.J.; Ventrucci, M.; Yang, S; (2020) <arXiv:2012.11767>. Both the parametric and semi-parametric models are available. The semi-parametric model relies on INLA'. The INLA package can be obtained from <https://www.r-inla.org/>.

Reads water network simulation data in Epanet text-based .inp and .rpt formats into R. Also reads results from Epanet-msx'. Provides basic summary information and plots. The README file has a quick introduction. See <https://www.epa.gov/water-research/epanet> for more information on the Epanet software for modeling hydraulic and water quality behavior of water piping systems.

This package provides a collection of functions that allows for easy and consistent use of environment variables. This includes setting, checking, retrieving, transforming, and validating values stored in environment variables.

This package provides a collection of nice plotting functions directly from a data.frame with limited customisation possibilities.

Analysis of dichotomous and polytomous response data using the explanatory item response modeling framework, as described in Bulut, Gorgun, & Yildirim-Erbasli (2021) <doi:10.3390/psych3030023>, Stanke & Bulut (2019) <doi:10.21449/ijate.515085>, and De Boeck & Wilson (2004) <doi:10.1007/978-1-4757-3990-9>. Generalized linear mixed modeling is used for estimating the effects of item-related and person-related variables on dichotomous and polytomous item responses.

Fits a variety of hidden Markov models, structured in an extended generalized linear model framework. See T. Rolf Turner, Murray A. Cameron, and Peter J. Thomson (1998) <doi:10.2307/3315677>, and Rolf Turner (2008) <doi:10.1016/j.csda.2008.01.029> and the references cited therein.