The remit of the European Clinical Trials Data Base (EudraCT <https://eudract.ema.europa.eu/> ), or ClinicalTrials.gov <https://clinicaltrials.gov/>, is to provide open access to summaries of all registered clinical trial results; thus aiming to prevent non-reporting of negative results and provide open-access to results to inform future research. The amount of information required and the format of the results, however, imposes a large extra workload at the end of studies on clinical trial units. In particular, the adverse-event-reporting component requires entering: each unique combination of treatment group and safety event; for every such event above, a further 4 pieces of information (body system, number of occurrences, number of subjects, number exposed) for non-serious events, plus an extra three pieces of data for serious adverse events (numbers of causally related events, deaths, causally related deaths). This package prepares the required statistics needed by EudraCT and formats them into the precise requirements to directly upload an XML file into the web portal, with no further data entry by hand.

Generate citations and references for R packages from CRAN or Bioconductor. Supports RIS and BibTeX formats with automatic DOI retrieval from GitHub repositories and published papers. Includes command-line interface for batch processing.

This package provides functions for computing test reliability and conditional standard error of measurement (CSEM) based on the methods described in the Reliability in Educational Measurement chapter of the 5th edition of "Educational Measurement" by Lee and Harris (2025, ISBN:9780197654965).

This package provides a set of extensions for the ergm package to fit weighted networks whose edge weights are ranks. See Krivitsky and Butts (2017) <doi:10.1177/0081175017692623> and Krivitsky, Hunter, Morris, and Klumb (2023) <doi:10.18637/jss.v105.i06>.

This package provides easy access to tidy education finance data using Bellwether's methodology to combine NCES F-33 Survey, Census Bureau Small Area Income Poverty Estimates (SAIPE), and community data from the ACS 5-Year Estimates. The package simplifies downloading, caching, and filtering education finance data by year and state, enabling researchers and analysts to explore K-12 education funding patterns, revenue sources, expenditure categories, and demographic factors across U.S. school districts.

This package creates family objects identical to stats family but for new links.

This package provides functions to numericise R objects (coerce to numeric objects), summarise MCMC (Monte Carlo Markov Chain) samples and calculate deviance residuals as well as R translations of some BUGS (Bayesian Using Gibbs Sampling), JAGS (Just Another Gibbs Sampler), STAN and TMB (Template Model Builder) functions.

Interactive labelling of scatter plots, volcano plots and Manhattan plots using a shiny and plotly interface. Users can hover over points to see where specific points are located and click points on/off to easily label them. Labels can be dragged around the plot to place them optimally. Plots can be exported directly to PDF for publication. For plots with large numbers of points, points can optionally be rasterized as a bitmap, while all other elements (axes, text, labels & lines) are preserved as vector objects. This can dramatically reduce file size for plots with millions of points such as Manhattan plots, and is ideal for publication.

This cointegration based Time Delay Neural Network Model hybrid model allows the researcher to make use of the information extracted by the cointegrating vector as an input in the neural network model.

This package provides tools to analyse human and mosquito behavioral interactions and to compute exposure to mosquito bites estimates. Using behavioral data for human individuals and biting patterns for mosquitoes, you will be able to compute hourly exposure for bed net users and non-users, and summarize (e.g. proportion indoors and outdoors, proportion per time periods, and proportion prevented by bed nets) or visualize these dynamics across a 24-hour cycle.

This is a package for exact Confidence Intervals for the difference between two independent or dependent proportions.

Digital simulation of electrochemical processes. Each function allows for implicit and explicit solution of the differential equation using methods like Euler, Backwards implicit, Runge Kutta 4, Crank Nicholson and Backward differentiation formula as well as different number of points for derivative approximation. Several electrochemical processes can be simulated such as: Chronoamperometry, Potential Step, Linear Sweep, Cyclic Voltammetry, Cyclic Voltammetry with electrochemical reaction followed by chemical reaction (EC mechanism) and CV with two following electrochemical reaction (EE mechanism). In update 1.1.0 has been added a general purpose CV function that allow to simulate up to 4 EE mechanism combined with chemical reaction for each species.Update 1.2.0 improved the accuracy of the measurements and allow personalized data resolution for simulation. Bibliography regarding this methods can be found in the following texts. Dieter Britz, Jorg Strutwolf (2016) <ISBN:978-3-319-30292-8>. Allen J. Bard, Larry R. Faulkner (2000) <ISBN:978-0-471-04372-0>.

It contains functions for dose calculation for different routes, fitting data to probability distributions, random number generation (Monte Carlo simulation) and calculation of systemic and carcinogenic risks. For more information see the publication: Barrio-Parra et al. (2019) "Human-health probabilistic risk assessment: the role of exposure factors in an urban garden scenario" <doi:10.1016/j.landurbplan.2019.02.005>.

The purpose of Early Warning Systems (EWS) is to detect accurately the occurrence of a crisis, which is represented by a binary variable which takes the value of one when the event occurs, and the value of zero otherwise. EWS are a toolbox for policymakers to prevent or attenuate the impact of economic downturns. Modern EWS are based on the econometric framework of Kauppi and Saikkonen (2008) <doi:10.1162/rest.90.4.777>. Specifically, this framework includes four dichotomous models, relying on a logit approach to model the relationship between yield spreads and future recessions, controlling for recession risk factors. These models can be estimated in a univariate or a balanced panel framework as in Candelon, Dumitrescu and Hurlin (2014) <doi:10.1016/j.ijforecast.2014.03.015>. This package provides both methods for estimating these models and a dataset covering 13 OECD countries over a period of 45 years. In addition, this package also provides methods for the analysis of the propagation mechanisms of an exogenous shock, as well as robust confidence intervals for these response functions using a block-bootstrap method as in Lajaunie (2021). This package constitutes a useful toolbox (data and functions) for scholars as well as policymakers.

This package produces tables for descriptive epidemiological analysis. These tables include attack rates, case fatality ratios, and mortality rates (with appropriate confidence intervals), with additional functionality to calculate Mantel-Haenszel odds, risk, and incidence rate ratios. The methods implemented follow standard epidemiological approaches described in Rothman et al. (2008, ISBN:978-0-19-513554-2). This package is part of the R4EPIs project <https://R4EPI.github.io/sitrep/>.

Estimation for high conditional quantiles based on quantile regression.

This package contains a set of clustering methods and evaluation metrics to select the best number of the clusters based on clustering stability. Two references describe the methodology: Fahimeh Nezhadmoghadam, and Jose Tamez-Pena (2021)<doi:10.1016/j.compbiomed.2021.104753>, and Fahimeh Nezhadmoghadam, et al.(2021)<doi:10.2174/1567205018666210831145825>.

An extension of knitr that adds flexibility in several ways. One common source of frustration with knitr is that it assumes the directory where the source file lives should be the working directory, which is often not true. ezknitr addresses this problem by giving you complete control over where all the inputs and outputs are, and adds several other convenient features to make rendering markdown/HTML documents easier.

Randomly generate a wide range of interaction networks with specified size, average degree, modularity, and topological structure. Sample nodes and links from within simulated networks randomly, by degree, by module, or by abundance. Simulations and sampling routines are implemented in FORTRAN', providing efficient generation times even for large networks. Basic visualization methods also included. Algorithms implemented here are described in de Aguiar et al. (2017) <arXiv:1708.01242>.

Measurement and partitioning of diversity, based on Tsallis entropy, following Marcon and Herault (2015) <doi:10.18637/jss.v067.i08>. entropart provides functions to calculate alpha, beta and gamma diversity of communities, including phylogenetic and functional diversity. Estimation-bias corrections are available.

Streamlines reproducible Rasch measurement theory analyses for ordinal item-response data, combining estimation routines from eRm', psychotools', mirt', iarm', and lavaan with consistent diagnostic, plotting, and reporting layers. Covers the four basic psychometric criteria summarised by Christensen et al. (2021) <doi:10.1111/sms.13908> -- unidimensionality, local independence, ordered response category thresholds, and invariance across subgroups -- together with item fit, targeting, reliability, category functioning, and descriptive item-response plots. A distinguishing feature is the use of simulation-based critical values to replace rule-of-thumb cutoffs for conditional infit mean-square, Yen's Q3 local-dependence statistic, the largest residual-PCA eigenvalue, and ordinal CFA fit indices. Outputs are knitr::kable() tables and ggplot2 figures suitable for direct inclusion in Quarto and R Markdown reports.

This package implements the Enhanced Portfolio Optimization (EPO) method as described in Pedersen, Babu and Levine (2021) <doi:10.2139/ssrn.3530390>.

An implementation of extended state-space SIR models developed by Song Lab at UM school of Public Health. There are several functions available by 1) including a time-varying transmission modifier, 2) adding a time-dependent quarantine compartment, 3) adding a time-dependent antibody-immunization compartment. Wang L. (2020) <doi:10.6339/JDS.202007_18(3).0003>.

This package provides a conservative, assumption-aware statistical consistency checker for published research results. Parses test statistics, effect sizes, and confidence intervals from text, PDF, HTML, and Word documents across multiple citation styles including American Psychological Association (APA), Harvard, Frontiers, PLOS ONE, Scientific Reports, Nature Human Behaviour, PeerJ, eLife, PNAS, and others. Recomputes effect sizes using all plausible variants when design is ambiguous, and validates internal consistency. Supports t-tests, F-tests/ANOVA, correlations, chi-square, z-tests, regression, and nonparametric tests. Provides statcheck'-compatible API functions for batch processing of files and directories. Explicitly tracks all assumptions and uncertainty in output. Detects decision errors (significance reversals) similar to statcheck'. Note: this package is under active development and results should be independently verified. Use is at the sole responsibility of the user. Contributions and verification reports are welcome.