This package provides a fast and scalable linear mixed-effects model (LMM) estimation algorithm for analysis of single-cell differential expression. The algorithm uses summary-level statistics and requires less computer memory to fit the LMM.

Use Rmarkdown First method to build your package. Start your package with documentation, functions, examples and tests in the same unique file. Everything can be set from the Rmarkdown template file provided in your project, then inflated as a package. Inflating the template copies the relevant chunks and sections in the appropriate files required for package development.

"This package quantifies the provenance of sediments in a catchment or study area. Based on a characterization of the sediment sources and the end sediment mixtures, a mixing model algorithm is applied to the sediment mixtures to estimate the relative contribution of each potential source. The package includes several graphs to help users in their data understanding, such as box plots, correlation, PCA, and LDA graphs. In addition, new developments such as the Consensus Ranking (CR), Consistent Tracer Selection (CTS), and Linear Variability Propagation (LVP) methods are included to correctly apply the fingerprinting technique and increase dataset and model understanding. A new method based on Conservative Balance (CB) method has also been included to enable the use of isotopic tracers.".

Design and simulate fuzzy logic systems using Type-1 and Interval Type-2 Fuzzy Logic. This toolkit includes with graphical user interface (GUI) and an adaptive neuro- fuzzy inference system (ANFIS). This toolkit is a continuation from the previous package ('FuzzyToolkitUoN'). Produced by the Intelligent Modelling & Analysis Group (IMA) and Lab for UnCertainty In Data and decision making (LUCID), University of Nottingham. A big thank you to the many people who have contributed to the development/evaluation of the toolbox. Please cite the toolbox and the corresponding paper <doi:10.1109/FUZZ48607.2020.9177780> when using it. More related papers can be found in the NEWS.

Calculates marginal effects based on logistic model objects such as glm or speedglm at the average (default) or at given values using finite differences. It also returns confidence intervals for said marginal effects and the p-values, which can easily be used as input in stargazer. The function only returns the essentials and is therefore much faster but not as detailed as other functions available to calculate marginal effects. As a result, it is highly suitable for large datasets for which other packages may require too much time or calculating power.

Returns the noncentrality parameter of the noncentral F distribution if probability of type I and type II error, degrees of freedom of the numerator and the denominator are given. It may be useful for computing minimal detectable differences for general ANOVA models. This program is documented in the paper of A. Baharev, S. Kemeny, On the computation of the noncentral F and noncentral beta distribution; Statistics and Computing, 2008, 18 (3), 333-340.

Similar to base's unique function, only optimized for working with data frames, especially those that contain date-time columns.

Read and process a large delimited file block by block. A block consists of all the contiguous rows that have the same value in the first field. The result can be returned as a list or a data.table, or even directly printed to an output file.

Generate SPSS'/'SAS styled frequency tables. Frequency tables are generated with variable and value label attributes where applicable with optional html output to quickly examine datasets.

Reads and writes ARFF files. ARFF (Attribute-Relation File Format) files are like CSV files, with a little bit of added meta information in a header and standardized NA values. They are quite often used for machine learning data sets and were introduced for the WEKA machine learning Java toolbox. See <https://waikato.github.io/weka-wiki/formats_and_processing/arff_stable/> for further info on ARFF and for <http://www.cs.waikato.ac.nz/ml/weka/> for more info on WEKA'. farff gets rid of the Java dependency that RWeka enforces, and it is at least a faster reader (for bigger files). It uses readr as parser back-end for the data section of the ARFF file. Consistency with RWeka is tested on Github and Travis CI with hundreds of ARFF files from OpenML'.

This package provides a joint model for large-scale, competing risks time-to-event data with singular or multiple longitudinal biomarkers, implemented with the efficient algorithms developed by Li and colleagues (2022) <doi:10.1155/2022/1362913> and <doi:10.48550/arXiv.2506.12741>. The time-to-event data is modelled using a (cause-specific) Cox proportional hazards regression model with time-fixed covariates. The longitudinal biomarkers are modelled using a linear mixed effects model. The association between the longitudinal submodel and the survival submodel is captured through shared random effects. It allows researchers to analyze large-scale data to model biomarker trajectories, estimate their effects on event outcomes, and dynamically predict future events from patientsâ past histories. A function for simulating survival and longitudinal data for multiple biomarkers is also included alongside built-in datasets.

This package provides a collection of functions designed to retrieve, filter and spatialize data from the Flora e Funga do Brasil dataset. For more information about the dataset, please visit <https://floradobrasil.jbrj.gov.br/consulta/>.

Estimate the of fractal dimension of a black area in 2D and 3D (slices) images using the box-counting method. See Klinkenberg B. (1994) <doi:10.1007/BF02065874>.

This R package can be used to generate artificial data conditionally on pre-specified (simulated or user-defined) relationships between the variables and/or observations. Each observation is drawn from a multivariate Normal distribution where the mean vector and covariance matrix reflect the desired relationships. Outputs can be used to evaluate the performances of variable selection, graphical modelling, or clustering approaches by comparing the true and estimated structures (B Bodinier et al (2021) <arXiv:2106.02521>).

Set of tools for detecting and analyzing Airborne Laser Scanning-derived Tropical Forest Canopy Gaps. Details were published in Silva and others (2019) <doi:10.1111/2041-210X.13211>.

Create local, regional, and global explanations for any machine learning model with forward marginal effects. You provide a model and data, and fmeffects computes feature effects. The package is based on the theory in: C. A. Scholbeck, G. Casalicchio, C. Molnar, B. Bischl, and C. Heumann (2022) <doi:10.48550/arXiv.2201.08837>.

Climate is a critical component limiting growing range of plant species, which also determines cultivar adaptation to a region. The evaluation of climate influence on fruit production is critical for decision-making in the design stage of orchards and vineyards and in the evaluation of the potential consequences of future climate. Bio- climatic indices and plant phenology are commonly used to describe the suitability of climate for growing quality fruit and to provide temporal and spatial information about regarding ongoing and future changes. fruclimadapt streamlines the assessment of climate adaptation and the identification of potential risks for grapevines and fruit trees. Procedures in the package allow to i) downscale daily meteorological variables to hourly values (Forster et al (2016) <doi:10.5194/gmd-9-2315-2016>), ii) estimate chilling and forcing heat accumulation (Miranda et al (2019) <https://ec.europa.eu/eip/agriculture/sites/default/files/fg30_mp5_phenology_critical_temperatures.pdf>), iii) estimate plant phenology (Schwartz (2012) <doi:10.1007/978-94-007-6925-0>), iv) calculate bioclimatic indices to evaluate fruit tree and grapevine adaptation (e.g. Badr et al (2017) <doi:10.3354/cr01532>), v) estimate the incidence of weather-related disorders in fruits (e.g. Snyder and de Melo-Abreu (2005, ISBN:92-5-105328-6) and vi) estimate plant water requirements (Allen et al (1998, ISBN:92-5-104219-5)).

This package provides a suite of functions to test for Functional Measurement Invariance (FMI) between two groups. Implements hierarchical permutation tests for configural, metric, and scalar invariance, adapting concepts from Multi-Group Confirmatory Factor Analysis (MGCFA) to functional data. Methods are based on concepts from: Meredith, W. (1993) <doi:10.1007/BF02294825>,5 Yao, F., Müller, H. G., & Wang, J. L. (2005) <doi:10.1198/016214504000001745>, and Lee, K. Y., & Li, L. (2022) <doi:10.1111/rssb.12471>.

This package implements a fast, flexible method for simulating continuous variables with specified rank correlations using the Imanâ Conover transformation (Iman & Conover, 1982 <doi:10.1080/03610918208812265>) and back-ranking. Includes plotting tools and error-diagnostics.

Using the idea of least trimmed square, it could automatically detects and removes outliers from data before estimating the coefficients. It is a robust machine learning tool which can be applied to gene-expression deconvolution technique. Yuning Hao, Ming Yan, Blake R. Heath, Yu L. Lei and Yuying Xie (2019) <doi:10.1101/358366>.

An optimizer of Fused-Sparse Structural Equation Models, which is the state of the art jointly fused sparse maximum likelihood function for structural equation models proposed by Xin Zhou and Xiaodong Cai (2018 <doi:10.1101/466623>).

Social Relations Analysis with roles ("Family SRM") are computed, using a structural equation modeling approach. Groups ranging from three members up to an unlimited number of members are supported and the mean structure can be computed. Means and variances can be compared between different groups of families and between roles.

All data sets from "Forecasting: methods and applications" by Makridakis, Wheelwright & Hyndman (Wiley, 3rd ed., 1998) <https://robjhyndman.com/forecasting/>.

In Australia, a financial year (or fiscal year) is the period from 1 July to 30 June of the following calendar year. As such, many databases need to represent and validate financial years efficiently. While the use of integer years with a convention that they represent the year ending is common, it may lead to ambiguity with calendar years. On the other hand, string representations may be too inefficient and do not easily admit arithmetic operations. This package tries to make validation of financial years quicker while retaining clarity.