This package implements discrete time deterministic and stochastic age-structured population dynamics models described in Erguler and others (2016) <doi:10.1371/journal.pone.0149282> and Erguler and others (2017) <doi:10.1371/journal.pone.0174293>.

Package to incorporate change point analysis in ARIMA forecasting.

This package performs archetypal analysis by using Principal Convex Hull Analysis under a full control of all algorithmic parameters. It contains a set of functions for determining the initial solution, the optimal algorithmic parameters and the optimal number of archetypes. Post run tools are also available for the assessment of the derived solution. Morup, M., Hansen, LK (2012) <doi:10.1016/j.neucom.2011.06.033>. Hochbaum, DS, Shmoys, DB (1985) <doi:10.1287/moor.10.2.180>. Eddy, WF (1977) <doi:10.1145/355759.355768>. Barber, CB, Dobkin, DP, Huhdanpaa, HT (1996) <doi:10.1145/235815.235821>. Christopoulos, DT (2016) <doi:10.2139/ssrn.3043076>. Falk, A., Becker, A., Dohmen, T., Enke, B., Huffman, D., Sunde, U. (2018), <doi:10.1093/qje/qjy013>. Christopoulos, DT (2015) <doi:10.1016/j.jastp.2015.03.009> . Murari, A., Peluso, E., Cianfrani, Gaudio, F., Lungaroni, M., (2019), <doi:10.3390/e21040394>.

This package implements a multiple testing approach to the choice of a threshold gamma on the p-values using the Average Power Function (APF) and Bayes False Discovery Rate (FDR) robust estimation. Function apf_fdr() estimates both quantities from either raw data or p-values. Function apf_plot() produces smooth graphs and tables of the relevant results. Details of the methods can be found in Quatto P, Margaritella N, et al. (2019) <doi:10.1177/0962280219844288>.

This package provides a collection of methods for both the rank-based estimates and least-square estimates to the Accelerated Failure Time (AFT) model. For rank-based estimation, it provides approaches that include the computationally efficient Gehan's weight and the general's weight such as the logrank weight. Details of the rank-based estimation can be found in Chiou et al. (2014) <doi:10.1007/s11222-013-9388-2> and Chiou et al. (2015) <doi:10.1002/sim.6415>. For the least-square estimation, the estimating equation is solved with generalized estimating equations (GEE). Moreover, in multivariate cases, the dependence working correlation structure can be specified in GEE's setting. Details on the least-squares estimation can be found in Chiou et al. (2014) <doi:10.1007/s10985-014-9292-x>.

Predicts amyloid proteins using random forests trained on the n-gram encoded peptides. The implemented algorithm can be accessed from both the command line and shiny-based GUI.

Read, manipulate and write voxel spaces. Voxel spaces are read from text-based output files of the AMAPVox software. AMAPVox is a LiDAR point cloud voxelisation software that aims at estimating leaf area through several theoretical/numerical approaches. See more in the article Vincent et al. (2017) <doi:10.23708/1AJNMP> and the technical note Vincent et al. (2021) <doi:10.23708/1AJNMP>.

Calculates concentration and dispersion in ordered rating scales. It implements various measures of concentration and dispersion to describe what researchers variably call agreement, concentration, consensus, dispersion, or polarization among respondents in ordered data. It also implements other related measures to classify distributions. In addition to a generic city-block based concentration measure and a generic dispersion measure, the package implements various measures, including van der Eijk's (2001) <DOI: 10.1023/A:1010374114305> measure of agreement A, measures of concentration by Leik, Tatsle and Wierman, Blair and Lacy, Kvalseth, Berry and Mielke, Reardon, and Garcia-Montalvo and Reynal-Querol. Furthermore, the package provides an implementation of Galtungs AJUS-system to classify distributions, as well as a function to identify the position of multiple modes.

This package provides tools for downloading and extracting data from the Copernicus "Agrometeorological indicators from 1979 to present derived from reanalysis" <https://cds.climate.copernicus.eu/cdsapp#!/dataset/sis-agrometeorological-indicators?tab=overview> (AgERA5).

This package provides scalable generalized linear and mixed effects models tailored for sequence count data analysis (e.g., analysis of 16S or RNA-seq data). Uses Dirichlet-multinomial sampling to quantify uncertainty in relative abundance or relative expression conditioned on observed count data. Implements scale models as a generalization of normalizations which account for uncertainty in scale (e.g., total abundances) as described in Nixon et al. (2025) <doi:10.1186/s13059-025-03609-3> and McGovern et al. (2025) <doi:10.1101/2025.08.05.668734>.

Streamline use of the All of Us Researcher Workbench (<https://www.researchallofus.org/data-tools/workbench/>)with tools to extract and manipulate data from the All of Us database. Increase interoperability with the Observational Health Data Science and Informatics ('OHDSI') tool stack by decreasing reliance of All of Us tools and allowing for cohort creation via Atlas'. Improve reproducible and transparent research using All of Us'.

This package provides a cross-platform R framework that facilitates processing of any number of Affymetrix microarray samples regardless of computer system. The only parameter that limits the number of chips that can be processed is the amount of available disk space. The Aroma Framework has successfully been used in studies to process tens of thousands of arrays. This package has actively been used since 2006.

This package provides a collection of tools for antitrust practitioners, including the ability to calibrate different consumer demand systems and simulate the effects of mergers under different competitive regimes.

Interface package for sala', the spatial network analysis library from the depthmapX software application. The R parts of the code are based on the rdepthmap package. Allows for the analysis of urban and building-scale networks and provides metrics and methods usually found within the Space Syntax domain. Methods in this package are described by K. Al-Sayed, A. Turner, B. Hillier, S. Iida and A. Penn (2014) "Space Syntax methodology", and also by A. Turner (2004) <https://discovery.ucl.ac.uk/id/eprint/2651> "Depthmap 4: a researcher's handbook".

An R API providing access to a relational database with macroeconomic data for Africa. The database contains >700 macroeconomic time series from mostly international sources, grouped into 50 macroeconomic and development-related topics. Series are carefully selected on the basis of data coverage for Africa, frequency, and relevance to the macro-development context. The project is part of the Kiel Institute Africa Initiative <https://www.ifw-kiel.de/institute/initiatives/kiel-institute-africa-initiative/>, which, amongst other things, aims to develop a parsimonious database with highly relevant indicators to monitor macroeconomic developments in Africa, accessible through a fast API and a web-based platform at <https://africamonitor.ifw-kiel.de/>. The database is maintained at the Kiel Institute for the World Economy <https://www.ifw-kiel.de/>.

Data on Asylum and Resettlement for the UK, provided by the Home Office <https://www.gov.uk/government/statistical-data-sets/immigration-system-statistics-data-tables>.

The Aligned Corpus Toolkit (act) is designed for linguists that work with time aligned transcription data. It offers functions to import and export various annotation file formats ('ELAN .eaf, EXMARaLDA .exb and Praat .TextGrid files), create print transcripts in the style of conversation analysis, search transcripts (span searches across multiple annotations, search in normalized annotations, make concordances etc.), export and re-import search results (.csv and Excel .xlsx format), create cuts for the search results (print transcripts, audio/video cuts using FFmpeg and video sub titles in Subrib title .srt format), modify the data in a corpus (search/replace, delete, filter etc.), interact with Praat using Praat'-scripts, and exchange data with the rPraat package. The package is itself written in R and may be expanded by other users.

This package provides a collection of several pharmacovigilance signal detection methods based on adaptive lasso. Additional lasso-based and propensity score-based signal detection approaches are also supplied. See Courtois et al <doi:10.1186/s12874-021-01450-3>.

Storing very large data objects on a local drive, while still making it possible to manipulate the data in an efficient manner.

Many complex plots are actually composite plots, such as oncoplot', funkyheatmap', upsetplot', etc. We can produce subplots using ggplot2 and combine them to create composite plots using aplot'. In this way, it is easy to customize these complex plots, by adding, deleting or modifying subplots in the final plot. This package provides a set of utilities to help users to create subplots and complex plots.

Estimation of regression models for sparse asynchronous longitudinal observations, where time-dependent response and covariates are mismatched and observed intermittently within subjects. Kernel weighted estimating equations are used for generalized linear models with either time-invariant or time-dependent coefficients. Cao, H., Li, J., and Fine, J. P. (2016) <doi:10.1214/16-EJS1141>. Cao, H., Zeng, D., and Fine, J. P. (2015) <doi:10.1111/rssb.12086>.

The functions proposed in this package allows to evaluate the process of measurement of the chemical components of water numerically or graphically. TSSS(), ICHS and datacheck() functions are useful to control the quality of measurements of chemical components of a sample of water. If one or more measurements include an error, the generated graph will indicate it with a position of the point that represents the sample outside the confidence interval. The function CI() allows to evaluate the possibility of contamination of a water sample after being obtained. Validation() is a function that allows to calculate the quality parameters of a technique for the measurement of a chemical component.

This package provides WHO 2007 References for School-age Children and Adolescents (5 to 19 years) (z-scores) with confidence intervals and standard errors around the prevalence estimates, taking into account complex sample designs. More information on the methods is available online: <https://www.who.int/tools/growth-reference-data-for-5to19-years>.

Helps enable adaptive management by codifying knowledge in the form of models generated from numerous analyses and data sets. Facilitates this process by storing all models and data sets in a single object that can be updated and saved, thus tracking changes in knowledge through time. A shiny application called AM Model Manager (modelMgr()) enables the use of these functions via a GUI.