Computes factorial A-, D- and E-optimal designs for two-colour cDNA microarray experiments.

Over sixty clustering algorithms are provided in this package with consistent input and output, which enables the user to try out algorithms swiftly. Additionally, 26 statistical approaches for the estimation of the number of clusters as well as the mirrored density plot (MD-plot) of clusterability are implemented. The packages is published in Thrun, M.C., Stier Q.: "Fundamental Clustering Algorithms Suite" (2021), SoftwareX, <DOI:10.1016/j.softx.2020.100642>. Moreover, the fundamental clustering problems suite (FCPS) offers a variety of clustering challenges any algorithm should handle when facing real world data, see Thrun, M.C., Ultsch A.: "Clustering Benchmark Datasets Exploiting the Fundamental Clustering Problems" (2020), Data in Brief, <DOI:10.1016/j.dib.2020.105501>.

Perform frequency distribution tables, associated histograms and polygons from vector, data.frame and matrix objects for numerical and categorical variables.

For including external figures into an assembled patchwork. This enables the creation of more complex figures that include images alongside plots.

Statistical tool set for population genetics. The package provides following functions: 1) estimators of genetic differentiation (FST), 2) regression analysis of environmental effects on genetic differentiation using generalized least squares (GLS) method, 3) interfaces to read and manipulate GENEPOP format data files). For more information, see Kitada, Nakamichi and Kishino (2020) <doi:10.1101/2020.01.30.927186>.

Perform factorial analysis with a menu and draw graphs interactively thanks to FactoMineR and a Shiny application.

Extracts features from biological sequences. It contains most features which are presented in related work and also includes features which have never been introduced before. It extracts numerous features from nucleotide and peptide sequences. Each feature converts the input sequences to discrete numbers in order to use them as predictors in machine learning models. There are many features and information which are hidden inside a sequence. Utilizing the package, users can convert biological sequences to discrete models based on chosen properties. References: iLearn Z. Chen et al. (2019) <DOI:10.1093/bib/bbz041>. iFeature Z. Chen et al. (2018) <DOI:10.1093/bioinformatics/bty140>. <https://CRAN.R-project.org/package=rDNAse>. PseKRAAC Y. Zuo et al. PseKRAAC: a flexible web server for generating pseudo K-tuple reduced amino acids composition (2017) <DOI:10.1093/bioinformatics/btw564>. iDNA6mA-PseKNC P. Feng et al. iDNA6mA-PseKNC: Identifying DNA N6-methyladenosine sites by incorporating nucleotide physicochemical properties into PseKNC (2019) <DOI:10.1016/j.ygeno.2018.01.005>. I. Dubchak et al. Prediction of protein folding class using global description of amino acid sequence (1995) <DOI:10.1073/pnas.92.19.8700>. W. Chen et al. Identification and analysis of the N6-methyladenosine in the Saccharomyces cerevisiae transcriptome (2015) <DOI:10.1038/srep13859>.

Wrapper for computing parameters for univariate distributions using MLE. It creates an object that stores d, p, q, r functions as well as parameters and statistics for diagnostics. Currently supports automated fitting from base and actuar packages. A manually fitting distribution fitting function is included to support directly specifying parameters for any distribution from ancillary packages.

This package provides a wrapper for the python module FIORA as well as a shiny'-App to facilitate data processing and visualization. FIORA allows to predict Mass-Spectra based on the SMILES code of chemical compounds. It is described in the Nature Communications article by Nowatzky (2025) <doi:10.1038/s41467-025-57422-4>.

This package provides a simple method to select the best model or best subset of variables using different types of data (binary, Gaussian or Poisson) and applying it in different contexts (parametric or non-parametric).

This package provides functional control charts for statistical process monitoring of functional data, using the methods of Capezza et al. (2020) <doi:10.1002/asmb.2507>, Centofanti et al. (2021) <doi:10.1080/00401706.2020.1753581>, Capezza et al. (2024) <doi:10.1080/00224065.2024.2383674>, Capezza et al. (2024) <doi:10.1080/00401706.2024.2327346>, Centofanti et al. (2025) <doi:10.1080/00224065.2024.2430978>, Capezza et al. (2025) <doi:10.48550/arXiv.2410.20138>. The package is thoroughly illustrated in the paper of Capezza et al (2023) <doi:10.1080/00224065.2023.2219012>.

Collect your data on digital marketing campaigns from Facebook Leads Ads using the Windsor.ai API <https://windsor.ai/api-fields/>.

Code for fitting and assessing models for the growth of trees. In particular for the Bayesian neighborhood competition linear regression model of Allen (2020): methods for model fitting and generating fitted/predicted values, evaluating the effect of competitor species identity using permutation tests, and evaluating model performance using spatial cross-validation.

Simplifies the process of importing and managing input-output matrices from Microsoft Excel into R, and provides a suite of functions for analysis. It leverages the R6 class for clean, memory-efficient object-oriented programming. Furthermore, all linear algebra computations are implemented in Rust to achieve highly optimized performance.

Estimates and provides inference for quantities that assess high dimensional mediation and potential surrogate markers including the direct effect of treatment, indirect effect of treatment, and the proportion of treatment effect explained by a surrogate/mediator; details are described in Zhou et al (2022) <doi:10.1002/sim.9352> and Zhou et al (2020) <doi:10.1093/biomet/asaa016>. This package relies on the optimization software MOSEK', <https://www.mosek.com>.

Streamlines the process of updating changelogs (NEWS.md) and versioning R packages developed in git repositories.

Include assessing site classes based on the stand height growth and establishing a nonlinear mixed-effect biomass model under different site classes based on the whole stand model to achieve more accurate estimation of carbon sequestration. In particular, a carbon sequestration potential productivity calculation method based on the potential mean annual increment is proposed. This package is applicable to both natural forests and plantations. It can quantitatively assess standâ s potential productivity, realized productivity, and possible improvement under certain site, and can be used in many aspects such as site quality assessment, tree species suitability evaluation, and forest degradation evaluation. Reference: Lei X, Fu L, Li H, et al (2018) <doi:10.11707/j.1001-7488.20181213>. Fu L, Sharma R P, Zhu G, et al (2017) <doi:10.3390/f8040119>.

This package provides tools for training and analysing fairness-aware gated neural networks for subgroup-aware prediction and interpretation in clinical datasets. Methods draw on prior work in mixture-of-experts neural networks by Jordan and Jacobs (1994) <doi:10.1007/978-1-4471-2097-1_113>, fairness-aware learning by Hardt, Price, and Srebro (2016) <doi:10.48550/arXiv.1610.02413>, and personalised treatment prediction for depression by Iniesta, Stahl, and McGuffin (2016) <doi:10.1016/j.jpsychires.2016.03.016>.

Supports the use of standardized folder names.

This package performs robust multiple testing for means in the presence of known and unknown latent factors presented in Fan et al.(2019) "FarmTest: Factor-Adjusted Robust Multiple Testing With Approximate False Discovery Control" <doi:10.1080/01621459.2018.1527700>. Implements a series of adaptive Huber methods combined with fast data-drive tuning schemes proposed in Ke et al.(2019) "User-Friendly Covariance Estimation for Heavy-Tailed Distributions" <doi:10.1214/19-STS711> to estimate model parameters and construct test statistics that are robust against heavy-tailed and/or asymmetric error distributions. Extensions to two-sample simultaneous mean comparison problems are also included. As by-products, this package contains functions that compute adaptive Huber mean, covariance and regression estimators that are of independent interest.

This package provides a tool to explore wide data sets, by detecting, ranking and plotting groups of statistically dependent columns.

This package provides a collection of user-friendly functions for assessing and visualizing fragility of individual studies (Walsh et al., 2014 <doi:10.1016/j.jclinepi.2013.10.019>; Lin, 2021 <doi:10.1111/jep.13428>), conventional pairwise meta-analyses (Atal et al., 2019 <doi:10.1016/j.jclinepi.2019.03.012>), and network meta-analyses of multiple treatments with binary outcomes (Xing et al., 2020 <doi:10.1016/j.jclinepi.2020.07.003>). The included functions are designed to: 1) calculate the fragility index (i.e., the minimal event status modifications that can alter the significance or non-significance of the original result) and fragility quotient (i.e., fragility index divided by sample size) at a specific significance level; 2) give the cases of event status modifications for altering the result's significance or non-significance and visualize these cases; 3) visualize the trend of statistical significance as event status is modified; 4) efficiently derive fragility indexes and fragility quotients at multiple significance levels, and visualize the relationship between these fragility measures against the significance levels; and 5) calculate fragility indexes and fragility quotients of multiple datasets (e.g., a collection of clinical trials or meta-analyses) and produce plots of their overall distributions. The outputs from these functions may inform the robustness of clinical results in terms of statistical significance and aid the interpretation of fragility measures. The usage of this package is illustrated in Lin et al. (2023 <doi:10.1016/j.ajog.2022.08.053>) and detailed in Lin and Chu (2022 <doi:10.1371/journal.pone.0268754>).

Four fertility models are fitted using non-linear least squares. These are the Hadwiger, the Gamma, the Model1 and Model2, following the terminology of the following paper: Peristera P. and Kostaki A. (2007). "Modeling fertility in modern populations". Demographic Research, 16(6): 141--194. <doi:10.4054/DemRes.2007.16.6>. Model based averaging is also supported.

This package implements fast and exact computation of Gaussian stochastic process with the Matern kernel using forward filtering and backward smoothing algorithm. It includes efficient implementations of the inverse Kalman filter, with applications such as estimating particle interaction functions. These tools support models with or without noise. Additionally, the package offers algorithms for fast parameter estimation in latent factor models, where the factor loading matrix is orthogonal, and latent processes are modeled by Gaussian processes. See the references: 1) Mengyang Gu and Yanxun Xu (2020), Journal of Computational and Graphical Statistics; 2) Xinyi Fang and Mengyang Gu (2024), <doi:10.48550/arXiv.2407.10089>; 3) Mengyang Gu and Weining Shen (2020), Journal of Machine Learning Research; 4) Yizi Lin, Xubo Liu, Paul Segall and Mengyang Gu (2025), <doi:10.48550/arXiv.2501.01324>.