Estimation of mixed models including a subject-specific variance which can be time and covariate dependent. In the joint model framework, the package handles left truncation and allows a flexible dependence structure between the competing events and the longitudinal marker. The estimation is performed under the frequentist framework, using the Marquardt-Levenberg algorithm. (Courcoul, Tzourio, Woodward, Barbieri, Jacqmin-Gadda (2023) <arXiv:2306.16785>).

Miscellaneous utilities, tools and helper functions for finding and searching files on disk, searching for and removing R objects from the workspace. Does not import or depend on any third party package, but on core R only (i.e. it may depend on packages with priority base').

Computes factorial A-, D- and E-optimal designs for two-colour cDNA microarray experiments.

This package implements a fuzzy clustering approach for ordinal Likert-type data using triangular fuzzy numbers (TFNs). The package extends the classical fuzzy C-means algorithm to better handle uncertainty in ordinal scales and includes automatic selection of the number of clusters using the Xie-Beni validity index. References: Coppi, R., D'Urso, P., and Giordani, P. (2012), "Fuzzy and possibilistic clustering for fuzzy data", <doi:10.1016/j.csda.2010.09.013>. Xie, X. L. and Beni, G. (1991), "A validity measure for fuzzy clustering", <doi:10.1109/34.85677>.

Multidimensional scaling (MDS) functions for various tasks that are beyond the beta stage and way past the alpha stage. Currently, options are available for weights, restrictions, classical scaling or principal coordinate analysis, transformations (linear, power, Box-Cox, spline, ordinal), outlier mitigation (rdop), out-of-sample estimation (predict), negative dissimilarities, fast and faster executions with low memory footprints, penalized restrictions, cross-validation-based penalty selection, supplementary variable estimation (explain), additive constant estimation, mixed measurement level distance calculation, restricted classical scaling, etc. More will come in the future. References. Busing (2024) "A Simple Population Size Estimator for Local Minima Applied to Multidimensional Scaling". Manuscript submitted for publication. Busing (2025) "Node Localization by Multidimensional Scaling with Iterative Majorization". Manuscript submitted for publication. Busing (2025) "Faster Multidimensional Scaling". Manuscript in preparation. Barroso and Busing (2025) "e-RDOP, Relative Density-Based Outlier Probabilities, Extended to Proximity Mapping". Manuscript submitted for publication.

Wrapper functions that interface with FSL <http://fsl.fmrib.ox.ac.uk/fsl/fslwiki/>, a powerful and commonly-used neuroimaging software, using system commands. The goal is to be able to interface with FSL completely in R, where you pass R objects of class nifti', implemented by package oro.nifti', and the function executes an FSL command and returns an R object of class nifti if desired.

Quantitatively analyse depth time-series data from pop-up satellite archival tags (PSATs) through the application of continuous wavelet transformation (CWT) combined with Principal Component Analysis (PCA), and k-means clustering. Import, crop, and plot depth time-depth records (TDRs). Using CWT to detect important signals within the non-stationary data, we create daily wavelet statistics to summarise vertical movements on different wavelet periods and combine with daily and diel depth statistics. Classify depth time-series with unsupervised k-means clustering into 24-hour periods of vertical movement behaviour with distinct patterns of vertical movement. Plot example days from each behaviour cluster, and plot the TDR coloured by cluster. Based on principals of combining CWT with k-means first developed by Sakamoto (2009) <doi:10.1371/journal.pone.0005379> and redeveloped by Beale (2026) <doi:10.21203/rs.3.rs-6907076/v1>.

Useful functions to translate text for multiple languages using online translators. For example, by translating error messages and descriptive analysis results into a language familiar to the user, it enables a better understanding of the information, thereby reducing the barriers caused by language. It offers several helper functions to query gene information to help interpretation of interested genes (e.g., marker genes, differential expression genes), and provides utilities to translate ggplot graphics. This package is not affiliated with any of the online translators. The developers do not take responsibility for the invoice it incurs when using this package, especially for exceeding the free quota.

This package provides tools for portfolio construction and risk analytics, including mean-variance optimization, conditional value at risk (expected shortfall) minimization, risk parity, regime clustering, correlation analysis, Monte Carlo simulation, and option pricing. Includes utilities for portfolio evaluation, clustering, and risk reporting. Methods are based in part on Markowitz (1952) <doi:10.1111/j.1540-6261.1952.tb01525.x>, Rockafellar and Uryasev (2000) <doi:10.21314/JOR.2000.038>, Maillard et al. (2010) <doi:10.3905/jpm.2010.36.4.060>, Black and Scholes (1973) <doi:10.1086/260062>, and Cox et al. (1979) <doi:10.1016/0304-405X(79)90015-1>.

This package provides functions for range estimation in birds based on Pennycuick (2008) and Pennycuick (1975), Flight program which compliments Pennycuick (2008) requires manual entry of birds which can be tedious when there are hundreds of birds to estimate. Implemented are two ODE methods discussed in Pennycuick (1975) and time-marching computation methods as in Pennycuick (1998) and Pennycuick (2008). See Pennycuick (1975, ISBN:978-0-12-249405-5), Pennycuick (1998) <doi:10.1006/jtbi.1997.0572>, and Pennycuick (2008, ISBN:9780080557816).

This package provides a function composition operator to chain a series of calls into a single function, mimicking the math notion of (f o g o h)(x) = h(g(f(x))). Inspired by pipeOp ('|>') since R4.1 and magrittr pipe ('%>%'), the operator build a pipe without putting data through, which is best for anonymous function accepted by utilities such as apply() and lapply().

Routines for forecasting univariate time series using Theta Models.

We facilitate the analysis of full factorial mating designs with mixed-effects models. The package contains six vignettes containing detailed examples.

Analysis of Bayesian adaptive enrichment clinical trial using Free-Knot Bayesian Model Averaging (FK-BMA) method of Maleyeff et al. (2024) for Gaussian data. Maleyeff, L., Golchi, S., Moodie, E. E. M., & Hudson, M. (2024) "An adaptive enrichment design using Bayesian model averaging for selection and threshold-identification of predictive variables" <doi:10.1093/biomtc/ujae141>.

New approaches to parallel coordinates plots for multivariate data visualization, including applications to clustering, outlier hunting and regression diagnostics. Includes general functions for multivariate nonparametric density and regression estimation, using parallel computation.

This package provides tools for fitting and analyzing 1D-4D nuclear magnetic resonance spectra with analytical models of peak shapes and peak groups. The package reads spectra in NMRPipe format, builds constrained parameter structures for chemical shifts, line widths, scalar couplings, volumes, and phases, and performs nonlinear least-squares optimization for iterative peak discovery or simultaneous fits across multiple spectra. It also provides methods for visualization, preprocessing, and kinetic analysis of 1D time-series data, including automated phase optimization, solvent suppression, time-domain correction for frequency shifts and line broadening, modeling spectra as linear combinations of two component spectra, and exponential rate fitting.

Flexible parametric mixture and non-mixture cure models for time-to-event data.

Create vector tile archives in PMTiles format from sf spatial data frames. Supports Mapbox Vector Tile ('MVT') and MapLibre Tile ('MLT') output formats. Uses a Rust backend via extendr for fast, in-memory tiling with zero external system dependencies.

This package provides a friendly interface for modifying data frames with a sequence of piped commands built upon the tidyverse Wickham et al., (2019) <doi:10.21105/joss.01686> . The majority of commands wrap dplyr mutate statements in a convenient way to concisely solve common issues that arise when tidying small to medium data sets. Includes smart defaults and allows flexible selection of columns via tidyselect'.

This package implements the algorithm by Briefs and Bläser (2025) <https://openreview.net/forum?id=8PHOPPH35D>, based on the approach of Gupta and Bläser (2024) <doi:10.1609/aaai.v38i18.30023>. It determines, for a structural causal model (SCM) whose directed edges form a tree, whether each parameter is unidentifiable, 1-identifiable or 2-identifiable (other cases cannot occur), using a randomized algorithm with provable running time O(n^3 log^2 n).

Estimation, model selection and goodness-of-fit of (1) factor copula models for mixed continuous and discrete data in Kadhem and Nikoloulopoulos (2021) <doi:10.1111/bmsp.12231>; (2) bi-factor and second-order copula models for item response data in Kadhem and Nikoloulopoulos (2023) <doi:10.1007/s11336-022-09894-2>; (3) factor tree copula models for item response data in Kadhem and Nikoloulopoulos (2022) <arXiv:2201.00339>.

Time-based joins to analyze sequence of events, both in memory and out of memory. after_join() joins two tables of events, while funnel_start() and funnel_step() join events in the same table. With the type argument, you can switch between different funnel types, like first-first and last-firstafter.

Compute labels for a test set according to the k-Nearest Neighbors classification. This is a fast way to do k-Nearest Neighbors classification because the distance matrix -between the features of the observations- is an input to the function rather than being calculated in the function itself every time.

This package provides a set of functions that facilitate basic data manipulation and cleaning for statistical analysis including functions for finding and fixing duplicate rows and columns, missing values, outliers, and special characters in column and row names and functions for checking data consistency, distribution, quality, reliability, and structure.