Draws gene or genome maps and comparisons between these, in a publication-grade manner. Starting from simple, common files, it will draw postscript or PDF files that can be sent as such to journals.

Interface for g3-lollipop JavaScript library. Visualize genetic mutation data using an interactive lollipop diagram in RStudio or your web browser.

Fit Generalized Linear Models to continuous and count outcomes, as well as estimate the prevalence of misrepresentation of an important binary predictor. Misrepresentation typically arises when there is an incentive for the binary factor to be misclassified in one direction (e.g., in insurance settings where policy holders may purposely deny a risk status in order to lower the insurance premium). This is accomplished by treating a subset of the response variable as resulting from a mixture distribution. Model parameters are estimated via the Expectation Maximization algorithm and standard errors of the estimates are obtained from closed forms of the Observed Fisher Information. For an introduction to the models and the misrepresentation framework, see Xia et. al., (2023) <https://variancejournal.org/article/73151-maximum-likelihood-approaches-to-misrepresentation-models-in-glm-ratemaking-model-comparisons>.

Accurate and computationally efficient p-value calculation methods for a general family of Fisher type statistics (GFisher). The GFisher covers Fisher's combination, Good's statistic, Lancaster's statistic, weighted Z-score combination, etc. It allows a flexible weighting scheme, as well as an omnibus procedure that automatically adapts proper weights and degrees of freedom to a given data. The new p-value calculation methods are based on novel ideas of moment-ratio matching and joint-distribution approximation. The technical details can be found in Hong Zhang and Zheyang Wu (2020) <arXiv:2003.01286>.

An implementation of the generalized graded unfolding model (GGUM) in R, see Roberts, Donoghue, and Laughlin (2000) <doi:10.1177/01466216000241001>). It allows to simulate data sets based on the GGUM. It fits the GGUM and the GUM, and it retrieves item and person parameter estimates. Several plotting functions are available (item and test information functions; item and test characteristic curves; item category response curves). Additionally, there are some functions that facilitate the communication between R and GGUM2004'. Finally, a model-fit checking utility, MODFIT(), is also available.

Description: For the risk, progression, and response to treatment of many complex diseases, it has been increasingly recognized that gene-environment interactions play important roles beyond the main genetic and environmental effects. In practical interaction analyses, outliers in response variables and covariates are not uncommon. In addition, missingness in environmental factors is routinely encountered in epidemiological studies. The developed package consists of five robust approaches to address the outliers problems, among which two approaches can also accommodate missingness in environmental factors. Both continuous and right censored responses are considered. The proposed approaches are based on penalization and sparse boosting techniques for identifying important interactions, which are realized using efficient algorithms. Beyond the gene-environment analysis, the developed package can also be adopted to conduct analysis on interactions between other types of low-dimensional and high-dimensional data. (Mengyun Wu et al (2017), <doi:10.1080/00949655.2018.1523411>; Mengyun Wu et al (2017), <doi:10.1002/gepi.22055>; Yaqing Xu et al (2018), <doi:10.1080/00949655.2018.1523411>; Yaqing Xu et al (2019), <doi:10.1016/j.ygeno.2018.07.006>; Mengyun Wu et al (2021), <doi:10.1093/bioinformatics/btab318>).

Simulation of, and fitting models for, Generalised Network Autoregressive (GNAR) time series models which take account of network structure, potentially with exogenous variables. Such models are described in Knight et al. (2020) <doi:10.18637/jss.v096.i05> and Nason and Wei (2021) <doi:10.1111/rssa.12875>. Diagnostic tools for GNAR(X) models can be found in Nason et al. (2023) <doi:10.48550/arXiv.2312.00530>.

Automated General-to-Specific (GETS) modelling of the mean and variance of a regression, and indicator saturation methods for detecting and testing for structural breaks in the mean, see Pretis, Reade and Sucarrat (2018) <doi:10.18637/jss.v086.i03> for an overview of the package. In advanced use, the estimator and diagnostics tests can be fully user-specified, see Sucarrat (2021) <doi:10.32614/RJ-2021-024>.

Build display tables from tabular data with an easy-to-use set of functions. With its progressive approach, we can construct display tables with a cohesive set of table parts. Table values can be formatted using any of the included formatting functions. Footnotes and cell styles can be precisely added through a location targeting system. The way in which gt handles things for you means that you don't often have to worry about the fine details.

Regression using GMDH algorithms from Prof. Alexey G. Ivakhnenko. Group Method of Data Handling (GMDH), or polynomial neural networks, is a family of inductive algorithms that performs gradually complicated polynomial models and selecting the best solution by an external criterion. In other words, inductive GMDH algorithms give possibility finding automatically interrelations in data, and selecting an optimal structure of model or network. The package includes GMDH Combinatorial, GMDH MIA (Multilayered Iterative Algorithm), GMDH GIA (Generalized Iterative Algorithm) and GMDH Combinatorial with Active Neurons.

This package provides a Gibbs sampler corresponding to a Group Inverse-Gamma Gamma (GIGG) regression model with adjustment covariates. Hyperparameters in the GIGG prior specification can either be fixed by the user or can be estimated via Marginal Maximum Likelihood Estimation. Jonathan Boss, Jyotishka Datta, Xin Wang, Sung Kyun Park, Jian Kang, Bhramar Mukherjee (2021) <arXiv:2102.10670>.

At Novartis, we aimed at standardizing the set of diagnostic plots used for modeling activities in order to reduce the overall effort required for generating such plots. For this, we developed a guidance that proposes an adequate set of diagnostics and a toolbox, called ggPMX to execute them. ggPMX is a toolbox that can generate all diagnostic plots at a quality sufficient for publication and submissions using few lines of code. This package focuses on plots recommended by ISoP <doi:10.1002/psp4.12161>. While not required, you can get/install the R lixoftConnectors package in the Monolix installation, as described at the following url <https://monolixsuite.slp-software.com/r-functions/2024R1/installation-and-initialization>. When lixoftConnectors is available, R can use Monolix directly to create the required Chart Data instead of exporting it from the Monolix gui.

This package provides a framework to detect Differential Item Functioning (DIF) in Generalized Partial Credit Models (GPCM) and special cases of the GPCM as proposed by Schauberger and Mair (2019) <doi:10.3758/s13428-019-01224-2>. A joint model is set up where DIF is explicitly parametrized and penalized likelihood estimation is used for parameter selection. The big advantage of the method called GPCMlasso is that several variables can be treated simultaneously and that both continuous and categorical variables can be used to detect DIF.

Conducts causal inference with interactive fixed-effect models. It imputes counterfactuals for each treated unit using control group information based on a linear interactive fixed effects model that incorporates unit-specific intercepts interacted with time-varying coefficients. This method generalizes the synthetic control method to the case of multiple treated units and variable treatment periods, and improves efficiency and interpretability.

This package provides a collection of datasets and simplified functions for an introductory (geo)statistics module at University College London. Provides functionality for compositional, directional and spatial data, including ternary diagrams, Wulff and Schmidt stereonets, and ordinary kriging interpolation. Implements logistic and (additive and centred) logratio transformations. Computes vector averages and concentration parameters for the von-Mises distribution. Includes a collection of natural and synthetic fractals, and a simulator for deterministic chaos using a magnetic pendulum example. The main purpose of these functions is pedagogical. Researchers can find more complete alternatives for these tools in other packages such as compositions', robCompositions', sp', gstat and RFOC'. All the functions are written in plain R, with no compiled code and a minimal number of dependencies. Theoretical background and worked examples are available at <https://tinyurl.com/UCLgeostats/>.

This package provides tools to access, search, and download global 3D building footprint datasets (3D-GloBFP) generated by Che et al. (2024) <doi:10.5194/essd-16-5357-2024>. The package includes functions to retrieve metadata, filter by bounding box, and download building height tiles.

This package makes available 50 objective functions for benchmarking the performance of global optimization algorithms.

Spatio-temporal radial basis functions (optimization, prediction and cross-validation), summary statistics from cross-validation, Adjusting distance-based linear regression model and generation of the principal coordinates of a new individual from Gower's distance.

This package provides tools to build and work with bilateral generalized-mean price indexes (and by extension quantity indexes), and indexes composed of generalized-mean indexes (e.g., superlative quadratic-mean indexes, GEKS). Covers the core mathematical machinery for making bilateral price indexes, computing price relatives, detecting outliers, and decomposing indexes, with wrappers for all common (and many uncommon) index-number formulas. Implements and extends many of the methods in Balk (2008, <doi:10.1017/CBO9780511720758>), von der Lippe (2007, <doi:10.3726/978-3-653-01120-3>), and the CPI manual (2020, <doi:10.5089/9781484354841.069>).

Make it easy to create simplified trial summary (TS) domain based on FDA FDA guide <https://github.com/TuCai/phuse/blob/master/inst/examples/07_genTS/www/Simplified_TS_Creation_Guide_v2.pdf>.

This package provides a Bayesian model selection approach for generalized linear mixed models. Currently, GLMMselect can be used for Poisson GLMM and Bernoulli GLMM. GLMMselect can select fixed effects and random effects simultaneously. Covariance structures for the random effects are a product of a unknown scalar and a known semi-positive definite matrix. GLMMselect can be widely used in areas such as longitudinal studies, genome-wide association studies, and spatial statistics. GLMMselect is based on Xu, Ferreira, Porter, and Franck (202X), Bayesian Model Selection Method for Generalized Linear Mixed Models, Biometrics, under review.

Gaussian processes are flexible distributions to model functional data. Whilst theoretically appealing, they are computationally cumbersome except for small datasets. This package implements two methods for scaling Gaussian process inference in Stan'. First, a sparse approximation of the likelihood that is generally applicable and, second, an exact method for regularly spaced data modeled by stationary kernels using fast Fourier methods. Utility functions are provided to compile and fit Stan models using the cmdstanr interface. References: Hoffmann and Onnela (2025) <doi:10.18637/jss.v112.i02>.

Enables users to create simple plots of biological culture plates as well as microplates. Both continuous and discrete values can be plotted onto the plate layout.

Assists in the plotting and functional smoothing of traits measured over time and the extraction of features from these traits, implementing the SET (Smoothing and Extraction of Traits) method described in Brien et al. (2020) Plant Methods, 16. Smoothing of growth trends for individual plants using natural cubic smoothing splines or P-splines is available for removing transient effects and segmented smoothing is available to deal with discontinuities in growth trends. There are graphical tools for assessing the adequacy of trait smoothing, both when using this and other packages, such as those that fit nonlinear growth models. A range of per-unit (plant, pot, plot) growth traits or features can be extracted from the data, including single time points, interval growth rates and other growth statistics, such as maximum growth or days to maximum growth. The package also has tools adapted to inputting data from high-throughput phenotyping facilities, such from a Lemna-Tec Scananalyzer 3D (see <https://www.youtube.com/watch?v=MRAF_mAEa7E/> for more information). The package growthPheno can also be installed from <http://chris.brien.name/rpackages/>.