This is a dataset package for GANPA, which implements a network-based gene weighting approach to pathway analysis. This package includes data useful for GANPA, such as a functional association network, pathways, an expression dataset and multi-subunit proteins.

This package provides tools for planning and simulating recurrent event trials with overdispersed count endpoints analyzed using negative binomial (or Poisson) rate models. Implements sample size and power calculations for fixed designs with variable accrual, dropout, maximum follow-up, and event gaps, including methods of Zhu and Lakkis (2014) <doi:10.1002/sim.5947> and Friede and Schmidli (2010) <doi:10.3414/ME09-02-0060>. Supports group sequential designs by adding calendar-time analysis schedules compatible with the gsDesign package and by estimating blinded information at interim looks. Includes simulation utilities for recurrent events (including seasonal rates), interim data truncation, and Wald-based inference for treatment rate ratios.

The multiple contrast tests for univariate were proposed by Munko, Ditzhaus, Pauly, Smaga, and Zhang (2023) <doi:10.48550/arXiv.2306.15259>. Recently, they were extended to the multivariate functional data in Munko, Ditzhaus, Pauly, and Smaga (2024) <doi:10.48550/arXiv.2406.01242>. These procedures enable us to evaluate the overall hypothesis regarding equality, as well as specific hypotheses defined by contrasts. In particular, we can perform post hoc tests to examine particular comparisons of interest. Different experimental designs are supported, e.g., one-way and multi-way analysis of variance for functional data.

This package contains functions to create life history parameter plots from raw data. The plots are created using ggplot2', and calculations done using the tidyverse collection of packages. The package contains references to FishBase (Froese R., Pauly D., 2023) <https://www.fishbase.se/>.

This package provides a collection of different indices and visualization techniques for evaluate the seed germination process in ecophysiological studies (Lozano-Isla et al. 2019) <doi:10.1111/1440-1703.1275>.

Reference datasets commonly used in the geosciences. These include standard atomic weights of the elements, a periodic table, a list of minerals including their abbreviations and chemistry, geochemical data of reservoirs (primitive mantle, continental crust, mantle, basalts, etc.), decay constants and isotopic ratios frequently used in geochronology, color codes of the chronostratigraphic chart. In addition, the package provides functions for basic queries of atomic weights, the list of minerals, and chronostratigraphic chart colors. All datasets are fully referenced, and a BibTeX file containing the references is included.

This package performs generalized Susceptible-Exposed-Infected-Recovered (SEIR) modeling to predict epidemic curves. The method is described in Peng et al. (2020) <doi:10.1101/2020.02.16.20023465>.

Quantitative trait loci mapping and genome wide association analysis are used to find candidate molecular marker or region associated with phenotype based on linkage analysis and linkage disequilibrium. Gene expression quantitative trait loci mapping is used to find candidate molecular marker or region associated with gene expression. In this package, we applied the method in Liu W. (2011) <doi:10.1007/s00122-011-1631-7> and Gusev A. (2016) <doi:10.1038/ng.3506> to genome and transcriptome wide association study, which is aimed at revealing the association relationship between phenotype and molecular markers, expression levels, molecular markers nested within different related expression effect and expression effect nested within different related molecular marker effect. F test based on full and reduced model are performed to obtain p value or likelihood ratio statistic. The best linear model can be obtained by stepwise regression analysis.

GEE estimation of the parameters in mean structures with possible correlation between the outcomes. User-specified mean link and variance functions are allowed, along with observation weighting. The M in the name geeM is meant to emphasize the use of the Matrix package, which allows for an implementation based fully in R.

These are GreedyExperimentalDesign Java dependency libraries. Note: this package has no functionality of its own and should not be installed as a standalone package without GreedyExperimentalDesign.

Fit joint models of survival and multivariate longitudinal data. The longitudinal data is specified by generalised linear mixed models. The joint models are fit via maximum likelihood using an approximate expectation maximisation algorithm. Bernhardt (2015) <doi:10.1016/j.csda.2014.11.011>.

Estimation of partial correlation matrix using ridge penalty followed by thresholding and reestimation. Under multivariate Gaussian assumption, the matrix constitutes an Gaussian graphical model (GGM).

Tests of goodness-of-fit based on a kernel smoothing of the data. References: Pavà a (2015) <doi:10.18637/jss.v066.c01>.

Focused on extracting important data from track points such as speed, distance, elevation difference and azimuth.(PLAZA, J. et al., 2022) <doi:10.1016/j.applanim.2022.105643>.

This package provides a convenient R interface to the Genotype-Tissue Expression (GTEx) Portal API. The GTEx project is a comprehensive public resource for studying tissue-specific gene expression and regulation in human tissues. Through systematic analysis of RNA sequencing data from 54 non-diseased tissue sites across nearly 1000 individuals, GTEx provides crucial insights into the relationship between genetic variation and gene expression. This data is accessible through the GTEx Portal API enabling programmatic access to human gene expression data. For more information on the API, see <https://gtexportal.org/api/v2/redoc>.

This package provides a ggplot2 extension that supports arbitrary hand-crafted colourable & fillable shapes. New shapes may be feature requested via a Github issue.

The GeneCycle package implements the approaches of Wichert et al. (2004) <doi:10.1093/bioinformatics/btg364>, Ahdesmaki et al. (2005) <doi:10.1186/1471-2105-6-117> and Ahdesmaki et al. (2007) <DOI:10.1186/1471-2105-8-233> for detecting periodically expressed genes from gene expression time series data.

This package provides functions for inference of ploidy from (Genotyping-by-sequencing) GBS data, including a function to infer allelic ratios and allelic proportions in a Bayesian framework.

This package provides tools for sparse regression modelling with grouped predictors using the group subset selection penalty. Uses coordinate descent and local search algorithms to rapidly deliver near optimal estimates. The group subset penalty can be combined with a group lasso or ridge penalty for added shrinkage. Linear and logistic regression are supported, as are overlapping groups.

This package implements readers and writers for file formats associated with genetics data. Reading and writing Plink BED/BIM/FAM and GCTA binary GRM formats is fully supported, including a lightning-fast BED reader and writer implementations. Other functions are readr wrappers that are more constrained, user-friendly, and efficient for these particular applications; handles Plink and Eigenstrat tables (FAM, BIM, IND, and SNP files). There are also make functions for FAM and BIM tables with default values to go with simulated genotype data.

This package provides adaptive association tests for SNP level, gene level and pathway level analyses.

Divide and conquer approach for estimating low-rank and sparse coefficient matrix in the generalized co-sparse factor regression. Please refer the manuscript Mishra, Aditya, Dipak K. Dey, Yong Chen, and Kun Chen. Generalized co-sparse factor regression. Computational Statistics & Data Analysis 157 (2021): 107127 for more details.

This package provides functions to identify European NUTS (Nomenclature of Territorial Units for Statistics) regions for geographic coordinates (latitude/longitude) using Eurostat geospatial boundaries. Includes map-based visualisation of the matched regions for validation and exploration. Designed for regional data analysis, reproducible workflows, and integration with common geospatial R packages.

Datasets analysed in the book Antony Unwin (2024, ISBN:978-0367674007) "Getting (more out of) Graphics".