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Decision curve analysis is a method for evaluating and comparing prediction models that incorporates clinical consequences, requires only the data set on which the models are tested, and can be applied to models that have either continuous or dichotomous results. The ggscidca package adds coloured bars of discriminant relevance to the traditional decision curve. Improved practicality and aesthetics. This method was described by Balachandran VP (2015) <doi:10.1016/S1470-2045(14)71116-7>.
Mark your interesting genes on plot and support more parameters to handle your own gene set enrichment analysis plot.
R Interface to C API of GLPK, depends on GLPK Version >= 4.42.
This package contains ggplot2 geom for plotting brain atlases using simple features. The largest component of the package is the data for the two built-in atlases. Mowinckel & Vidal-Piñeiro (2020) <doi:10.1177/2515245920928009>.
Evaluate and validate the Geboes score for histological assessment of inflammation in ulcerative colitis. The original Geboes score from Geboes, et al. (2000) <doi:10.1136/gut.47.3.404>, binary version from Li, et al. (2019) <doi:10.1093/ecco-jcc/jjz022>, and continuous version from Magro, et al. (2020) <doi:10.1093/ecco-jcc/jjz123> are all described and implemented.
Hierarchical Bayesian models. The package provides tools to fit two response time models, using the population-based Markov Chain Monte Carlo.
This package provides tools to measure the reliability of an Information Retrieval test collection. It allows users to estimate reliability using Generalizability Theory and map those estimates onto well-known indicators such as Kendall tau correlation or sensitivity.
Defines window or bin boundaries for the analysis of genomic data. Boundaries are based on the inflection points of a cubic smoothing spline fitted to the raw data. Along with defining boundaries, a technique to evaluate results obtained from unequally-sized windows is provided. Applications are particularly pertinent for, though not limited to, genome scans for selection based on variability between populations (e.g. using Wright's fixations index, Fst, which measures variability in subpopulations relative to the total population).
Facilitates the creation of page layout visualizations in which words are represented as rectangles with sizes relating to the length of the words. Which then is divided in lines and pages for easy overview of up to quite large texts.
Colour palettes inspired by Studio Ghibli <https://en.wikipedia.org/wiki/Studio_Ghibli> films, ported to R for your enjoyment.
Density, distribution function, quantile function and random generation for the Generalized Binomial Distribution. Functions to compute the Clopper-Pearson Confidence Interval and the required sample size. Enhanced model for burn-in studies, where failures are tackled by countermeasures.
This package provides functions to explore datasets from the Global Biodiversity Information Facility (GBIF - <https://www.gbif.org/>) using a Shiny interface.
Offers the Generalized Berk-Jones (GBJ) test for set-based inference in genetic association studies. The GBJ is designed as an alternative to tests such as Berk-Jones (BJ), Higher Criticism (HC), Generalized Higher Criticism (GHC), Minimum p-value (minP), and Sequence Kernel Association Test (SKAT). All of these other methods (except for SKAT) are also implemented in this package, and we additionally provide an omnibus test (OMNI) which integrates information from each of the tests. The GBJ has been shown to outperform other tests in genetic association studies when signals are correlated and moderately sparse. Please see the vignette for a quickstart guide or Sun and Lin (2017) <arXiv:1710.02469> for more details.
Reads data collected from wearable acceleratometers as used in sleep and physical activity research. Currently supports file formats: binary data from GENEActiv <https://activinsights.com/>, .bin-format from GENEA devices (not for sale), and .cwa-format from Axivity <https://axivity.com>. Further, it has functions for reading text files with epoch level aggregates from Actical', Fitbit', Actiwatch', ActiGraph', and PhilipsHealthBand'. Primarily designed to complement R package GGIR <https://CRAN.R-project.org/package=GGIR>.
This package provides a collection of tools to create, use and maintain modularized model code written in the modeling language GAMS (<https://www.gams.com/>). Out-of-the-box GAMS does not come with support for modularized model code. This package provides the tools necessary to convert a standard GAMS model to a modularized one by introducing a modularized code structure together with a naming convention which emulates local environments. In addition, this package provides tools to monitor the compliance of the model code with modular coding guidelines.
This package provides tools for creating publication-ready dimensionality reduction plots, including Principal Component Analysis (PCA), t-Distributed Stochastic Neighbor Embedding (t-SNE), and Uniform Manifold Approximation and Projection (UMAP). This package helps visualize high-dimensional data with options for custom labels, density plots, and faceting, using the ggplot2 framework Wickham (2016) <doi:10.1007/978-3-319-24277-4>.
Computes the sample probability value (p-value) for the estimated coefficient from a standard genome-wide univariate regression. It computes the exact finite-sample p-value under the assumption that the measured phenotype (the dependent variable in the regression) has a known Bernoulli-normal mixture distribution. Finite-sample genome-wide regression p-values (Gwrpv) with a non-normally distributed phenotype (Gregory Connor and Michael O'Neill, bioRxiv 204727 <doi:10.1101/204727>).
Calculates the cost of crossing in terms of the number of individuals and generations, which is theoretically formulated by Servin et al. (2004) <DOI:10.1534/genetics.103.023358>. This package has been designed for selecting appropriate parental genotypes and find the most efficient crossing scheme for gene pyramiding, especially for plant breeding.
This package provides a tool to sensitivity analysis using SOBOL (Sobol, 1993) and AMA (Dell'Oca et al. 2017 <doi:10.5194/hess-21-6219-2017>) indices. It allows to identify the most sensitive parameter or parameters of a model.
Fit the penalized Cox models with both non-overlapping and overlapping grouped penalties including the group lasso, group smoothly clipped absolute deviation, and group minimax concave penalty. The algorithms combine the MM approach and group-wise descent with some computational tricks including the screening, active set, and warm-start. Different tuning regularization parameter methods are provided.
Reads annual and quarterly financial reports from companies traded at B3, the Brazilian exchange <https://www.b3.com.br/>. All data is downloaded and imported from CVM's public ftp site <https://dados.cvm.gov.br/dados/CIA_ABERTA/>.
Create hexagonal heatmaps with ggplot2', using the size aesthetic to variably size each hexagon.
Routines for fitting various joint (and univariate) regression models, with several types of covariate effects, in the presence of equations errors association.
Mainly contains a plotting function ggseg3d(), and data of two standard brain atlases (Desikan-Killiany and aseg). By far, the largest bit of the package is the data for each of the atlases. The functions and data enable users to plot tri-surface mesh plots of brain atlases, and customise these by projecting colours onto the brain segments based on values in their own data sets. Functions are wrappers for plotly'. Mowinckel & Vidal-Piñeiro (2020) <doi:10.1177/2515245920928009>.