Approaches a group sparse solution of an underdetermined linear system. It implements the proximal gradient algorithm to solve a lower regularization model of group sparse learning. For details, please refer to the paper "Y. Hu, C. Li, K. Meng, J. Qin and X. Yang. Group sparse optimization via l_p,q regularization. Journal of Machine Learning Research, to appear, 2017".

This package performs geographically weighted Lasso regressions. Find optimal bandwidth, fit a geographically weighted lasso or ridge regression, and make predictions. These methods are specially well suited for ecological inferences. Bandwidth selection algorithm is from A. Comber and P. Harris (2018) <doi:10.1007/s10109-018-0280-7>.

This package implements the gene-based segregation test(GESE) and the weighted GESE test for identifying genes with causal variants of large effects for family-based sequencing data. The methods are described in Qiao, D. Lange, C., Laird, N.M., Won, S., Hersh, C.P., et al. (2017). <DOI:10.1002/gepi.22037>. Gene-based segregation method for identifying rare variants for family-based sequencing studies. Genet Epidemiol 41(4):309-319. More details can be found at <http://scholar.harvard.edu/dqiao/gese>.

Four graph-based tests are provided for testing whether two samples are from the same distribution. It works for both continuous data and discrete data.

This package provides Generalized Inferences based on exact distributions and exact probability statements for mixed effect models, provided by such papers as Weerahandi and Yu (2020) <doi:10.1186/s40488-020-00105-w> under the widely used Compound Symmetric Covariance structure. The package returns the estimation of the coefficients in random and fixed part of the mixed models by generalized inference.

This package provides the necessary functions to identify and extract a selection of already available barcode constructs (Cornils, K. et al. (2014) <doi:10.1093/nar/gku081>) and freely choosable barcode designs from next generation sequence (NGS) data. Furthermore, it offers the possibility to account for sequence errors, the calculation of barcode similarities and provides a variety of visualisation tools (Thielecke, L. et al. (2017) <doi:10.1038/srep43249>).

This package provides a unified algorithm, blockwise-majorization-descent (BMD), for efficiently computing the solution paths of the group-lasso penalized least squares, logistic regression, Huberized SVM and squared SVM. The package is an implementation of Yang, Y. and Zou, H. (2015) <doi:10.1007/s11222-014-9498-5>.

An optim-style implementation of the Stochastic Quasi-Gradient Differential Evolution (SQG-DE) optimization algorithm first published by Sala, Baldanzini, and Pierini (2018; <doi:10.1007/978-3-319-72926-8_27>). This optimization algorithm fuses the robustness of the population-based global optimization algorithm "Differential Evolution" with the efficiency of gradient-based optimization. The derivative-free algorithm uses population members to build stochastic gradient estimates, without any additional objective function evaluations. Sala, Baldanzini, and Pierini argue this algorithm is useful for difficult optimization problems under a tight function evaluation budget. This package can run SQG-DE in parallel and sequentially.

Gene-Ranking Analysis of Pathway Expression (GRAPE) is a tool for summarizing the consensus behavior of biological pathways in the form of a template, and for quantifying the extent to which individual samples deviate from the template. GRAPE templates are based only on the relative rankings of the genes within the pathway and can be used for classification of tissue types or disease subtypes. GRAPE can be used to represent gene-expression samples as vectors of pathway scores, where each pathway score indicates the departure from a given collection of reference samples. The resulting pathway- space representation can be used as the feature set for various applications, including survival analysis and drug-response prediction. Users of GRAPE should use the following citation: Klein MI, Stern DF, and Zhao H. GRAPE: A pathway template method to characterize tissue-specific functionality from gene expression profiles. BMC Bioinformatics, 18:317 (June 2017).

Functionalities to compute model based genetic components i.e. genotypic variance, phenotypic variance and heritability for given traits of different genotypes from replicated data using methodology explained by Burton, G. W. & Devane, E. H. (1953) (<doi:10.2134/agronj1953.00021962004500100005x>) and Allard, R.W. (2010, ISBN:8126524154).

Provide specialized ggplot2 layers and scales for spatial uncertainty visualization, including bivariate choropleth maps, pixel maps, glyph maps, and exceedance probability maps.

An RStudio addin for teaching and learning making plot using the ggplot2 package. You can learn each steps of making plot by clicking your mouse without coding. You can get resultant code for the plot.

Local structure in genomic data often induces dependence between observations taken at different genomic locations. Ignoring this dependence leads to underestimation of the standard error of parameter estimates. This package uses block bootstrapping to estimate asymptotically correct standard errors of parameters from any standard generalised linear model that may be fit by the glm() function.

This package implements the generalized Gauss Markov regression, this is useful when both predictor and response have uncertainty attached to them and also when covariance within the predictor, within the response and between the predictor and the response is present. Base on the results published in guide ISO/TS 28037 (2010) <https://www.iso.org/standard/44473.html>.

Easily explore data by creating ggplots through a (shiny-)GUI. R-code to recreate graph provided.

Add mean comparison annotations to a ggplot'. This package provides an easy way to indicate if two or more groups are significantly different in a ggplot'. Usually you do not need to specify the test method, you only need to tell stat_compare() whether you want to perform a parametric test or a nonparametric test, and stat_compare() will automatically choose the appropriate test method based on your data. For comparisons between two groups, the p-value is calculated by t-test (parametric) or Wilcoxon rank sum test (nonparametric). For comparisons among more than two groups, the p-value is calculated by One-way ANOVA (parametric) or Kruskal-Wallis test (nonparametric).

Scrapes Google Citation pages and creates data frames of citations over time.

GitHub apps provide a powerful way to manage fine grained programmatic access to specific git repositories, without having to create dummy users, and which are safer than a personal access token for automated tasks. This package extends the gh package to let you authenticate and interact with GitHub <https://docs.github.com/en/rest/overview> in R as an app.

Fast, model-agnostic implementation of different H-statistics introduced by Jerome H. Friedman and Bogdan E. Popescu (2008) <doi:10.1214/07-AOAS148>. These statistics quantify interaction strength per feature, feature pair, and feature triple. The package supports multi-output predictions and can account for case weights. In addition, several variants of the original statistics are provided. The shape of the interactions can be explored through partial dependence plots or individual conditional expectation plots. DALEX explainers, meta learners ('mlr3', tidymodels', caret') and most other models work out-of-the-box.

This package provides seamless access to the WEkEO Harmonised Data Access (HDA) API, enabling users to query, download, and process data efficiently from the HDA platform. With hdar', researchers and data scientists can integrate the extensive HDA datasets into their R workflows, enhancing their data analysis capabilities. Comprehensive information on the API functionality and usage is available at <https://gateway.prod.wekeo2.eu/hda-broker/docs>.

Calculate an optimal embedding of a set of data points into low-dimensional hyperbolic space. This uses the strain-minimizing hyperbolic embedding of Keller-Ressel and Nargang (2019), see <arXiv:1903.08977>.

Identifies chromatin interaction modules by constructing a Hi-C contact network based on statistically significant interactions, followed by network clustering. The method enables comparison of module connectivity across two Hi-C datasets and is capable of detecting cell-type-specific regulatory modules. By integrating network analysis with chromatin conformation data, this approach provides insights into the spatial organization of the genome and its functional implications in gene regulation. Author: Sora Yoon (2025) <https://github.com/ysora/HiCociety>.

Hierarchical and single-level non-negative matrix factorization. Several NMF algorithms are available.

Predict hatch and emergence timing for a wide range of wild fishes using the effective value framework (Sparks et al., (2019) <DOI:10.1139/cjfas-2017-0468>). hatchR offers users access to established phenological models and the flexibility to incorporate custom parameterizations using external datasets.