Constructs shrinkage estimators of high-dimensional mean-variance portfolios and performs high-dimensional tests on optimality of a given portfolio. The techniques developed in Bodnar et al. (2018 <doi:10.1016/j.ejor.2017.09.028>, 2019 <doi:10.1109/TSP.2019.2929964>, 2020 <doi:10.1109/TSP.2020.3037369>, 2021 <doi:10.1080/07350015.2021.2004897>) are central to the package. They provide simple and feasible estimators and tests for optimal portfolio weights, which are applicable for large p and large n situations where p is the portfolio dimension (number of stocks) and n is the sample size. The package also includes tools for constructing portfolios based on shrinkage estimators of the mean vector and covariance matrix as well as a new Bayesian estimator for the Markowitz efficient frontier recently developed by Bauder et al. (2021) <doi:10.1080/14697688.2020.1748214>.

General (multi-allelic) Hardy-Weinberg equilibrium problem from an objective Bayesian testing standpoint. This aim is achieved through the identification of a class of priors specifically designed for this testing problem. A class of intrinsic priors under the full model is considered. This class is indexed by a tuning quantity, the training sample size, as discussed in Consonni, Moreno and Venturini (2010). These priors are objective, satisfy Savage's continuity condition and have proved to behave extremely well for many statistical testing problems.

Shiny-App that allows to annotate vectors of texts to predefined categories by hand.

This package provides a comprehensive suite of spatial functions created to analyze and assess data heterogeneity and climate variability in spatial datasets. This package is specifically designed to address the challenges associated with characterizing and understanding complex spatial patterns in environmental and climate-related data.

Efficient implementations of the following multiple changepoint detection algorithms: Efficient Sparsity Adaptive Change-point estimator by Moen, Glad and Tveten (2023) <doi:10.48550/arXiv.2306.04702> , Informative Sparse Projection for Estimating Changepoints by Wang and Samworth (2017) <doi:10.1111/rssb.12243>, and the method of Pilliat et al (2023) <doi:10.1214/23-EJS2126>.

This package implements hierarchical conformal prediction for clustered data with missing responses. The method uses repeated cluster-level splitting and within-cluster subsampling to accommodate dependence, and inverse-probability weighting to correct distribution shift induced by missingness. Conditional densities are estimated by inverting fitted conditional quantiles (linear quantile regression or quantile regression forests), and p-values are aggregated across resampling and splitting steps using the Cauchy combination test.

Identifying labeled compounds in a 13C-tracer experiment in non-targeted fashion is a cumbersome process. This package facilitates such type of analyses by providing high level quality control plots, deconvoluting and evaluating spectra and performing a multitude of tests in an automatic fashion. The main idea is to use changing intensity ratios of ion pairs from peak list generated with xcms as candidates and evaluate those against base peak chromatograms and spectra information within the raw measurement data automatically. The functionality is described in Hoffmann et al. (2018) <doi:10.1021/acs.analchem.8b00356>.

This package provides functions to access data from the US Department of Housing and Urban Development <https://www.huduser.gov/portal/dataset/fmr-api.html>.

This package provides functions and datasets to support Smilde, Marini, Westerhuis and Liland (2025, ISBN: 978-1-394-21121-0) "Analysis of Variance for High-Dimensional Data - Applications in Life, Food and Chemical Sciences". This implements and imports a collection of methods for HD-ANOVA data analysis with common interfaces, result- and plotting functions, multiple real data sets and four vignettes covering a range different applications.

The HMS (Hierarchic Memetic Strategy) is a composite global optimization strategy consisting of a multi-population evolutionary strategy and some auxiliary methods. The HMS makes use of a dynamically-evolving data structure that provides an organization among the component populations. It is a tree with a fixed maximal height and variable internal node degree. Each component population is governed by a particular evolutionary engine. This package provides a simple R implementation with examples of using different genetic algorithms as the population engines. References: J. Sawicki, M. Å oÅ , M. SmoÅ ka, J. Alvarez-Aramberri (2022) <doi:10.1007/s11047-020-09836-w>.

Compute duration curves of daily flow series, both real and modeled, to be compared through indexes of flow duration curves. The package functions include comparative plots and goodness of fit tests. Flow duration curve indexes are based on: Yilmaz et al., (2008) <DOI:10.1029/2007WR006716>.

Fit, summarize and plot sinusoidal hysteretic processes using: two-step simple harmonic least squares, ellipse-specific non-linear least squares, the direct method, geometric least squares or linear least squares. See Yang, F and A. Parkhurst, "Efficient Estimation of Elliptical Hysteresis with Application to the Characterization of Heat Stress" <DOI:10.1007/s13253-015-0213-6>.

We provide a toolbox to conduct a Bayesian meta-analysis for estimating the current expansion rate of the Universe, called the Hubble constant H0, via time delay cosmography. The input data are Fermat potential difference and time delay estimates. For a robust inference, we assume a Student's t error for these inputs. Given these inputs, the meta-analysis produces posterior samples of the model parameters including the Hubble constant via Metropolis-Hastings within Gibbs. The package provides an option to implement repelling-attracting Metropolis-Hastings within Gibbs in a case where the parameter space has multiple modes.

Interface to the HERE REST APIs <https://developer.here.com/develop/rest-apis>: (1) geocode and autosuggest addresses or reverse geocode POIs using the Geocoder API; (2) route directions, travel distance or time matrices and isolines using the Routing', Matrix Routing and Isoline Routing APIs; (3) request real-time traffic flow and incident information from the Traffic API; (4) find request public transport connections and nearby stations from the Public Transit API; (5) request intermodal routes using the Intermodal Routing API; (6) get weather forecasts, reports on current weather conditions, astronomical information and alerts at a specific location from the Destination Weather API. Locations, routes and isolines are returned as sf objects.

Test the significance of coefficients in high dimensional generalized linear models.

In order to improve performance for HTTP API clients, httpcache provides simple tools for caching and invalidating cache. It includes the HTTP verb functions GET, PUT, PATCH, POST, and DELETE, which are drop-in replacements for those in the httr package. These functions are cache-aware and provide default settings for cache invalidation suitable for RESTful APIs; the package also enables custom cache-management strategies. Finally, httpcache includes a basic logging framework to facilitate the measurement of HTTP request time and cache performance.

Several handy plots for quickly looking at the relationship between two numeric vectors of equal length. Quickly visualize scatter plots, residual plots, qq-plots, box plots, confidence intervals, and prediction intervals.

Automatically displays the order and spatial weighting matrix of the distance between locations. This concept was derived from the research of Mubarak, Aslanargun, and Siklar (2021) <doi:10.52403/ijrr.20211150> and Mubarak, Aslanargun, and Siklar (2022) <doi:10.17654/0972361722052>. Distance data between locations can be imported from Ms. Excel', maps package or created in R programming directly. This package also provides 5 simulations of distances between locations derived from fictitious data, the maps package, and from research by Mubarak, Aslanargun, and Siklar (2022) <doi:10.29244/ijsa.v6i1p90-100>.

Returns a Hasse diagram of the layout structure (Bate and Chatfield (2016)) <doi:10.1080/00224065.2016.11918173> or the restricted layout structure (Bate and Chatfield (2016)) <doi:10.1080/00224065.2016.11918174> of an experimental design.

Clustering of high dimensional data with Hidden Markov Model on Variable Blocks (HMM-VB) fitted via Baum-Welch algorithm. Clustering is performed by the Modal Baum-Welch algorithm (MBW), which finds modes of the density function. Lin Lin and Jia Li (2017) <https://jmlr.org/papers/v18/16-342.html>.

This package provides a set of tools supporting more flexible heatmaps. The graphics is grid-like using the old graphics system. The main function is heatmap.n2(), which is a wrapper around the various functions constructing individual parts of the heatmap, like sidebars, picket plots, legends etc. The function supports zooming and splitting, i.e., having (unlimited) small heatmaps underneath each other in one plot deriving from the same data set, e.g., clustered and ordered by a supervised clustering method.

This package provides a streamlined tool for eplet analysis of donor and recipient HLA (human leukocyte antigen) mismatch. Messy, low-resolution HLA typing data is cleaned, and imputed to high-resolution using the NMDP (National Marrow Donor Program) haplotype reference database <https://haplostats.org/haplostats>. High resolution data is analyzed for overall or single antigen eplet mismatch using a reference table (currently supporting HLAMatchMaker <http://www.epitopes.net> versions 2 and 3). Data can enter or exit the workflow at different points depending on the user's aims and initial data quality.

This package provides a suite of functions to ping URLs and to time HTTP requests'. Designed to work with httr'.

This package provides a system for identifying diseases or events from healthcare databases and preparing data for epidemiological studies. It includes capabilities not supported by SQL', such as matching strings by stringr style regular expressions, and can compute comorbidity scores (Quan et al. (2005) <doi:10.1097/01.mlr.0000182534.19832.83>) directly on a database server. The implementation is based on dbplyr with full tidyverse compatibility.