This package implements the method developed by Cao and Kosorok (2011) for the significance analysis of thousands of features in high-dimensional biological studies. It is an asymptotically valid data-driven procedure to find critical values for rejection regions controlling the k-familywise error rate, false discovery rate, and the tail probability of false discovery proportion.

Two papers published in the early 2000's (Zeeberg, B.R., Feng, W., Wang, G. et al. (2003) <doi:10.1186/gb-2003-4-4-r28>) and (Zeeberg, B.R., Qin, H., Narashimhan, S., et al. (2005) <doi:10.1186/1471-2105-6-168>) implement GoMiner and High Throughput GoMiner ('HTGM') to map lists of genes to the Gene Ontology (GO) <https://geneontology.org>. Until recently, these were hosted on a server at The National Cancer Institute (NCI). In order to continue providing these services to the bio-medical community, I have developed stand-alone versions. The current package HTGM builds upon my recent package GoMiner'. The output of GoMiner is a heatmap showing the relationship of a single list of genes and the significant categories into which they map. High Throughput GoMiner ('HTGM') integrates the results of the individual GoMiner analyses. The output of HTGM is a heatmap showing the relationship of the significant categories derived from each gene list. The heatmap has only 2 axes, so the identity of the genes are unfortunately "integrated out of the equation." Because the graphic for the heatmap is implemented in Scalable Vector Graphics (SVG) technology, it is relatively easy to hyperlink each picture element to the relevant list of genes. By clicking on the desired picture element, the user can recover the "lost" genes.

Compute 21 summary measures of health inequality and its corresponding confidence intervals for ordered and non-ordered dimensions using disaggregated data. Measures for ordered dimensions (e.g., Slope Index of Inequality, Absolute Concentration Index) also accept individual and survey data.

This package provides an example HiC dataset and two examples of HiCociety outputs from a function named hic2community(). The data are intended for demonstration purposes only and kept small enough to be distributed via CRAN.

This package implements an efficient algorithm for fitting the entire regularization path of support vector machine models with elastic-net penalties using a generalized coordinate descent scheme. The framework also supports SCAD and MCP penalties. It is designed for high-dimensional datasets and emphasizes numerical accuracy and computational efficiency. This package implements the algorithms proposed in Tang, Q., Zhang, Y., & Wang, B. (2022) <https://openreview.net/pdf?id=RvwMTDYTOb>.

There are growing concerns on flow data in diverse fields including trade, migration, knowledge diffusion, disease spread, and transportation. The package is an effective visual support to learn the pattern of flow which is called halfcircle diagram. The flow between two nodes placed on the center line of a circle is represented using a half circle drawn from the origin to the destination in a clockwise direction. Through changing the order of nodes, the halfcircle diagram enables users to examine the complex relationship between bidirectional flow and each potential determinants. Furthermore, the halfmeancenter function, which calculates (un) weighted mean center of half circles, makes the comparison easier.

An S4 class and several functions which utilize internally stored datasets and gauging data enable 1d water level interpolation. The S4 class (WaterLevelDataFrame) structures the computation and visualisation of 1d water level information along the German federal waterways Elbe and Rhine. hyd1d delivers 1d water level data - extracted from the FLYS database - and validated gauging data - extracted from the hydrological database WISKI7 - package-internally. For computations near real time gauging data are queried externally from the PEGELONLINE REST API <https://pegelonline.wsv.de/webservice/dokuRestapi>.

Perform hierarchical Bayesian Aldrich-McKelvey scaling using Hamiltonian Monte Carlo via Stan'. Aldrich-McKelvey ('AM') scaling is a method for estimating the ideological positions of survey respondents and political actors on a common scale using positional survey data. The hierarchical versions of the Bayesian AM model included in this package outperform other versions both in terms of yielding meaningful posterior distributions for respondent positions and in terms of recovering true respondent positions in simulations. The package contains functions for preparing data, fitting models, extracting estimates, plotting key results, and comparing models using cross-validation. The original version of the default model is described in Bølstad (2024) <doi:10.1017/pan.2023.18>.

Allows users to create high-quality heatmaps from labelled, hierarchical data. Specifically, for data with a two-level hierarchical structure, it will produce a heatmap where each row and column represents a category at the lower level. These rows and columns are then grouped by the higher-level group each category belongs to, with the names for each category and groups shown in the margins. While other packages (e.g. dendextend') allow heatmap rows and columns to be arranged by groups only, hhmR also allows the labelling of the data at both the category and group level.

This package provides a simple implementation of doughnut plots - pie charts with a blank center. The package is named after Homer Simpson - arguably the best-known lover of doughnuts.

Offers methods for visualizing, modelling, and forecasting high-dimensional functional time series, also known as functional panel data. Documentation about hdftsa is provided via the paper by Cristian F. Jimenez-Varon, Ying Sun and Han Lin Shang (2024, <doi:10.1080/10618600.2024.2319166>).

Probabilistic models describing the behavior of workload and queue on a High Performance Cluster and computing GRID under FIFO service discipline basing on modified Kiefer-Wolfowitz recursion. Also sample data for inter-arrival times, service times, number of cores per task and waiting times of HPC of Karelian Research Centre are included, measurements took place from 06/03/2009 to 02/30/2011. Functions provided to import/export workload traces in Standard Workload Format (swf). Stability condition of the model may be verified either exactly, or approximately. Stability analysis: see Rumyantsev and Morozov (2017) <doi:10.1007/s10479-015-1917-2>, workload recursion: see Rumyantsev (2014) <doi:10.1109/PDCAT.2014.36>.

This package provides a set of objects and functions for Bayes Linear emulation and history matching. Core functionality includes automated training of emulators to data, diagnostic functions to ensure suitability, and a variety of proposal methods for generating waves of points. For details on the mathematical background, there are many papers available on the topic (see references attached to function help files or the below references); for details of the functions in this package, consult the manual or help files. Iskauskas, A, et al. (2024) <doi:10.18637/jss.v109.i10>. Bower, R.G., Goldstein, M., and Vernon, I. (2010) <doi:10.1214/10-BA524>. Craig, P.S., Goldstein, M., Seheult, A.H., and Smith, J.A. (1997) <doi:10.1007/978-1-4612-2290-3_2>.

Create compressed, interactive HTML (Hypertext Markup Language) reports with embedded Python code, custom JS ('JavaScript') and CSS (Cascading Style Sheets), and wrappers for CanvasXpress plots, networks and more. Based on <https://pypi.org/project/py-report-html/>, its sister project.

An implementation for high-dimensional time series analysis methods, including factor model for vector time series proposed by Lam and Yao (2012) <doi:10.1214/12-AOS970> and Chang, Guo and Yao (2015) <doi:10.1016/j.jeconom.2015.03.024>, martingale difference test proposed by Chang, Jiang and Shao (2023) <doi:10.1016/j.jeconom.2022.09.001>, principal component analysis for vector time series proposed by Chang, Guo and Yao (2018) <doi:10.1214/17-AOS1613>, cointegration analysis proposed by Zhang, Robinson and Yao (2019) <doi:10.1080/01621459.2018.1458620>, unit root test proposed by Chang, Cheng and Yao (2022) <doi:10.1093/biomet/asab034>, white noise test proposed by Chang, Yao and Zhou (2017) <doi:10.1093/biomet/asw066>, CP-decomposition for matrix time series proposed by Chang et al. (2023) <doi:10.1093/jrsssb/qkac011> and Chang et al. (2024) <doi:10.48550/arXiv.2410.05634>, and statistical inference for spectral density matrix proposed by Chang et al. (2022) <doi:10.48550/arXiv.2212.13686>.

Facilitates the analysis and evaluation of hydrologic model output and time-series data with functions focused on comparison of modeled (simulated) and observed data, period-of-record statistics, and trends.

Estimates parameters in Mixture Transition Distribution (MTD) models, a class of high-order Markov chains. The set of relevant pasts (lags) is selected using either the Bayesian Information Criterion or the Forward Stepwise and Cut algorithms. Other model parameters (e.g. transition probabilities and oscillations) can be estimated via maximum likelihood estimation or the Expectation-Maximization algorithm. Additionally, hdMTD includes a perfect sampling algorithm that generates samples of an MTD model from its invariant distribution. For theory, see Ost & Takahashi (2023) <http://jmlr.org/papers/v24/22-0266.html>.

The hydReng package provides a set of functions for hydraulic engineering tasks and natural hazard assessments. It includes basic hydraulics (wetted area, wetted perimeter, flow, flow velocity, flow depth, and maximum flow) for open channels with arbitrary geometry under uniform flow conditions. For structures such as circular pipes, weirs, and gates, the package includes calculations for pressure flow, backwater depth, and overflow over a weir crest. Additionally, it provides formulas for calculating bedload transport. The formulas used can be found in standard literature on hydraulics, such as Bollrich (2019, ISBN:978-3-410-29169-5) or Hager (2011, ISBN:978-3-642-77430-0).

This package provides a suite of diagnostic tools for hierarchical (multilevel) linear models. The tools include not only leverage and traditional deletion diagnostics (Cook's distance, covratio, covtrace, and MDFFITS) but also convenience functions and graphics for residual analysis. Models can be fit using either lmer in the lme4 package or lme in the nlme package.

Detection of haplotype patterns that include single nucleotide polymorphisms (SNPs) and non-contiguous haplotypes that are associated with a phenotype. Methods for implementing HTRX are described in Yang Y, Lawson DJ (2023) <doi:10.1093/bioadv/vbad038> and Barrie W, Yang Y, Irving-Pease E.K, et al (2024) <doi:10.1038/s41586-023-06618-z>.

This package provides various tests for comparing high-dimensional mean vectors in two sample populations.

Holistic Multimodel Domain Analysis (HMDA) is a robust and transparent framework designed for exploratory machine learning research, aiming to enhance the process of feature assessment and selection. HMDA addresses key limitations of traditional machine learning methods by evaluating the consistency across multiple high-performing models within a fine-tuned modeling grid, thereby improving the interpretability and reliability of feature importance assessments. Specifically, it computes Weighted Mean SHapley Additive exPlanations (WMSHAP), which aggregate feature contributions from multiple models based on weighted performance metrics. HMDA also provides confidence intervals to demonstrate the stability of these feature importance estimates. This framework is particularly beneficial for analyzing complex, multidimensional datasets common in health research, supporting reliable exploration of mental health outcomes such as suicidal ideation, suicide attempts, and other psychological conditions. Additionally, HMDA includes automated procedures for feature selection based on WMSHAP ratios and performs dimension reduction analyses to identify underlying structures among features. For more details see Haghish (2025) <doi:10.13140/RG.2.2.32473.63846>.

This package provides a broad collection of datasets focused on health, biomechanics, and human motion. It includes clinical, physiological, and kinematic information from diverse sources, covering aspects such as surgery outcomes, vital signs, rheumatoid arthritis, osteoarthritis, accelerometry, gait analysis, motion sensing, and biomechanics experiments. Designed for researchers, analysts, and students, the package facilitates exploration and analysis of data related to health monitoring, physical activity, and rehabilitation.

Core set of low-level utilities common across the hubverse'. Used to interact with hubverse schema, Hub configuration files and model outputs and designed to be primarily used internally by other hubverse packages. See Reich et al. (2022) <doi:10.2105/AJPH.2022.306831> for an overview of Collaborative Hubs.