It is used to construct run sequences with minimum changes for half replicate of two level factorial run order. Experimenter can save time and resources by minimizing the number of changes in levels of individual factor and therefore the total number of changes. It consists of the function minimal_hrtlf(). This technique can be employed to any half replicate of two level factorial run order where the number of factors are greater than two. In Design of Experiments (DOE) theory, two level of a factor can be represented as integers e.g. - 1 for low and 1 for high. User is expected to enter total number of factors to be considered in the experiment. minimal_hrtlf() provides the required run sequences for the input number of factors. The output also gives the number of changes of each factor along with total number of changes in the run sequence. Due to restricted randomization the minimally changed run sequences of half replicate of two level factorial run order will be affected by trend effect. The output also provides the Trend Factor value of the run order. Trend factor value will lies between 0 to 1. Higher the values, lesser the influence of trend effects on the run order.

Implementation of multiple approaches to perform inference in high-dimensional models.

Build better balance in causal inference models. halfmoon helps you assess propensity score models for balance between groups using metrics like standardized mean differences and visualization techniques like mirrored histograms. halfmoon supports both weighting and matching techniques.

When considering count data, it is often the case that many more zero counts than would be expected of some given distribution are observed. It is well established that data such as this can be reliably modelled using zero-inflated or hurdle distributions, both of which may be applied using the functions in this package. Bayesian analysis methods are used to best model problematic count data that cannot be fit to any typical distribution. The package functions are flexible and versatile, and can be applied to varying count distributions, parameter estimation with or without explanatory variable information, and are able to allow for multiple hurdles as it is also not uncommon that count data have an abundance of large-number observations which would be considered outliers of the typical distribution. In lieu of throwing out data or misspecifying the typical distribution, these extreme observations can be applied to a second, extreme distribution. With the given functions of this package, such a two-hurdle model may be easily specified in order to best manage data that is both zero-inflated and over-dispersed.

Allows to evaluate Higher Order Assortativity of complex networks defined through objects of class igraph from the package of the same name. The package returns a result also for directed and weighted graphs. References, Arcagni, A., Grassi, R., Stefani, S., & Torriero, A. (2017) <doi:10.1016/j.ejor.2017.04.028> Arcagni, A., Grassi, R., Stefani, S., & Torriero, A. (2021) <doi:10.1016/j.jbusres.2019.10.008> Arcagni, A., Cerqueti, R., & Grassi, R. (2023) <doi:10.48550/arXiv.2304.01737>.

This package contains various functions for data analysis, notably helpers and diagnostics for Bayesian modelling using Stan.

This package implements the estimators and algorithms described in Chapters 8 and 9 of the book "The Fundamentals of Heavy Tails: Properties, Emergence, and Estimation" by Nair et al. (2022, ISBN:9781009053730). These include the Hill estimator, Moments estimator, Pickands estimator, Peaks-over-Threshold (POT) method, Power-law fit, and the Double Bootstrap algorithm.

This package provides a deterministic, framework-agnostic Domain-Specific Language for building HTML nodes and rendering them to a string.

This package implements an efficient algorithm for fitting the entire regularization path of quantile regression models with elastic-net penalties using a generalized coordinate descent scheme. The framework also supports SCAD and MCP penalties. It is designed for high-dimensional datasets and emphasizes numerical accuracy and computational efficiency. This package implements the algorithms proposed in Tang, Q., Zhang, Y., & Wang, B. (2022) <https://openreview.net/pdf?id=RvwMTDYTOb>.

Simulates stochastic hybrid models for transmission of infectious diseases in dynamic networks. It is a metapopulation model in which each node in the network is a sub-population and disease spreads within nodes and among them, combining two approaches: stochastic simulation algorithm (<doi:10.1146/annurev.physchem.58.032806.104637>) and individual-based approach, respectively. Equations that models spread within nodes are customizable and there are two link types among nodes: migration and influence (commuting). More information in Fernando S. Marques, Jose H. H. Grisi-Filho, Marcos Amaku et al. (2020) <doi:10.18637/jss.v094.i06>.

We provide an R tool for computation and nonparametric plug-in estimation of Highest Density Regions (HDRs) and general level sets in the directional setting. Concretely, circular and spherical HDRs can be reconstructed from a data sample following Saavedra-Nieves and Crujeiras (2021) <doi:10.1007/s11634-021-00457-4>. This library also contains two real datasets in the circular and spherical settings. The first one concerns a problem from animal orientation studies and the second one is related to earthquakes occurrences.

This package provides a streamlined tool for eplet analysis of donor and recipient HLA (human leukocyte antigen) mismatch. Messy, low-resolution HLA typing data is cleaned, and imputed to high-resolution using the NMDP (National Marrow Donor Program) haplotype reference database <https://haplostats.org/haplostats>. High resolution data is analyzed for overall or single antigen eplet mismatch using a reference table (currently supporting HLAMatchMaker <http://www.epitopes.net> versions 2 and 3). Data can enter or exit the workflow at different points depending on the user's aims and initial data quality.

Harriet was Charles Darwin's pet tortoise (possibly). harrietr implements some function to manipulate distance matrices and phylogenetic trees to make it easier to plot with ggplot2 and to manipulate using tidyverse tools.

Generates three inter-related genomic datasets: methylation, gene expression and protein expression having user specified cluster patterns. The simulation utilizes the realistic inter- and intra- relationships from real DNA methylation, mRNA expression and protein expression data from the TCGA ovarian cancer study, Chalise (2016) <doi:10.1016/j.cmpb.2016.02.011>.

Computes the key metrics for assessing the performance of a liquidity provider (LP) position in a weighted multi-asset Automated Market Maker (AMM) pool. Calculates the nominal and percentage impermanent loss (IL) by comparing the portfolio value inside the pool (based on the weighted geometric mean of price ratios) against the value of simply holding the assets outside the pool (based on the weighted arithmetic mean). The primary function, `impermanent_loss()`, incorporates the effect of earned trading fees to provide the LP's net profit and loss relative to a holding strategy, using a methodology derived from Tiruviluamala, N., Port, A., and Lewis, E. (2022) <doi:10.48550/arXiv.2203.11352>.

The correction is achieved under the assumption that non-migrating cells of the essay approximately form a quadratic flow profile due to frictional effects, compare law of Hagen-Poiseuille for flow in a tube. The script fits a conical plane to give xyz-coordinates of the cells. It outputs the number of migrated cells and the new corrected coordinates.

This package provides a pipeline to annotate chromatography peaks from the IDSL.IPA workflow <doi:10.1021/acs.jproteome.2c00120> with molecular formulas of a prioritized chemical space using an isotopic profile matching approach. The IDSL.UFA workflow only requires mass spectrometry level 1 (MS1) data for formula annotation. The IDSL.UFA methods was described in <doi:10.1021/acs.analchem.2c00563> .

This package provides functions read a dataframe containing one or more International Classification of Diseases Tenth Revision codes per subject. They return original data with injury categorizations and severity scores added.

Enable user to find the IP addresses which are used as VPN anonymizer, open proxies, web proxies and Tor exits. The package lookup the proxy IP address from IP2Proxy BIN Data file. You may visit <https://lite.ip2location.com> for free database download.

This package provides tools for easily and flexibly creating ggplot2 maps with inset maps. One crucial feature of maps is that they have fixed coordinate ratios, i.e., they cannot be distorted, which makes it difficult to manually place inset maps. This package provides functions to automatically position inset maps based on user-defined parameters, making it extremely easy to create maps with inset maps with minimal code.

You can access to open data published in Instituto Canario De Estadistica (ISTAC) APIs at <https://datos.canarias.es/api/estadisticas/>.

Confidence intervals for causal effects, using data collected in different experimental or environmental conditions. Hidden variables can be included in the model with a more experimental version.

Enables the user to find the country, region, district, city, coordinates, zip code, time zone, ISP, domain name, connection type, area code, weather, Mobile Country Code, Mobile Network Code, mobile brand name, elevation, usage type, address type, IAB category and Autonomous system information that any IP address or hostname originates from. Supported IPv4 and IPv6. Please visit <https://www.ip2location.com> to learn more. You may also want to visit <https://lite.ip2location.com> for free database download. This package requires IP2Location Python module. At the terminal, please run pip install IP2Location to install the module.

An implementation of the International Association for the Properties of Water (IAPWS) Formulation 1995 for the Thermodynamic Properties of Ordinary Water Substance for General and Scientific Use and on the releases for viscosity, conductivity, surface tension and melting pressure.