Takes the MinT implementation of the hts'<https://cran.r-project.org/package=hts> package and adapts it to allow degenerate hierarchical structures. Instead of the "nodes" argument, this function takes an S matrix which is more versatile in the structures it allows. For a demo, see Steinmeister and Pauly (2024)<doi:10.15488/17729>. The MinT algorithm is based on Wickramasuriya et al. (2019)<doi:10.1080/01621459.2018.1448825>.

Inference of chromosome-length haplotypes using a few haploid gametes of an individual. The gamete genotype data may be generated from various platforms including genotyping arrays and sequencing even with low-coverage. Hapi simply takes genotype data of known hetSNPs in single gamete cells as input and report the high-resolution haplotypes as well as confidence of each phased hetSNPs. The package also includes a module allowing downstream analyses and visualization of identified crossovers in the gametes.

This package provides functions to estimate population genetics summary statistics from haplo-diploid systems, where one sex is haploid and the other diploid (e.g. Hymenoptera insects). It implements a theoretical model assuming equal sex ratio, random mating, no selection, no mutation, and no gene flow, deriving expected genotype frequencies for both sexes under these equilibrium conditions. The package includes windowed calculations (operating over genomic sliding windows from VCF input) for allele and genotype frequencies, the inbreeding coefficient (Fis), pairwise Fst, Nei's H (gene diversity), Watterson's Theta, and sex-specific reference allele frequencies. Most statistics are agnostic to ploidy, allowing the package to be applied to both strictly haplo-diploid and fully diploid systems.

Interact with the application programming interface for the web annotation service Hypothes.is (See <http://hypothes.is> for more information.) Allows users to download data about public annotations, and create, retrieve, update, and delete their own annotations.

Automatically displays the order and spatial weighting matrix of the distance between locations. This concept was derived from the research of Mubarak, Aslanargun, and Siklar (2021) <doi:10.52403/ijrr.20211150> and Mubarak, Aslanargun, and Siklar (2022) <doi:10.17654/0972361722052>. Distance data between locations can be imported from Ms. Excel', maps package or created in R programming directly. This package also provides 5 simulations of distances between locations derived from fictitious data, the maps package, and from research by Mubarak, Aslanargun, and Siklar (2022) <doi:10.29244/ijsa.v6i1p90-100>.

Used for predicting a genotype's allelic state at a specific locus/QTL/gene. This is accomplished by using both a genotype matrix and a separate file which has categorizations about loci/QTL/genes of interest for the individuals in the genotypic matrix. A training population can be created from a panel of individuals who have been previously screened for specific loci/QTL/genes, and this previous screening could be summarized into a category. Using the categorization of individuals which have been genotyped using a genome wide marker platform, a model can be trained to predict what category (haplotype) an individual belongs in based on their genetic sequence in the region associated with the locus/QTL/gene. These trained models can then be used to predict the haplotype of a locus/QTL/gene for individuals which have been genotyped with a genome wide platform yet not genotyped for the specific locus/QTL/gene. This package is based off work done by Winn et al 2021. For more specific information on this method, refer to <doi:10.1007/s00122-022-04178-w>.

Allows to estimate and test high-dimensional mediation effects based on advanced mediator screening and penalized regression techniques. Methods used in the package refer to Zhang H, Zheng Y, Hou L, Liu L, HIMA: An R Package for High-Dimensional Mediation Analysis. Journal of Data Science. (2025). <doi:10.6339/25-JDS1192>.

This package provides functions for basic hydraulic calculations related to water flow in circular pipes both flowing full (under pressure), and partially full (gravity flow), and trapezoidal open channels. For pressure flow this includes friction loss calculations by solving the Darcy-Weisbach equation for head loss, flow or diameter, plotting a Moody diagram, matching a pump characteristic curve to a system curve, and solving for flows in a pipe network using the Hardy-Cross method. The Darcy-Weisbach friction factor is calculated using the Colebrook (or Colebrook-White equation), the basis of the Moody diagram, the original citation being Colebrook (1939) <doi:10.1680/ijoti.1939.13150>. For gravity flow, the Manning equation is used, again solving for missing parameters. The derivation of and solutions using the Darcy-Weisbach equation and the Manning equation are outlined in many fluid mechanics texts such as Finnemore and Maurer (2024, ISBN:978-1-264-78729-6). Some gradually- and rapidly-varied flow functions are included. For the Manning equation solutions, this package uses modifications of original code from the iemisc package by Irucka Embry.

Facilitates the analysis and evaluation of hydrologic model output and time-series data with functions focused on comparison of modeled (simulated) and observed data, period-of-record statistics, and trends.

This package provides a fast, vectorized hashmap that is built on top of C++ std::unordered_map <https://en.cppreference.com/w/cpp/container/unordered_map.html>. The map can hold any R object as key / value as long as it is serializable and supports vectorized insertion, lookup, and deletion.

Add, share and manage annotations for Shiny applications and R Markdown documents via hypothes.is'.

The Ljung-Box test is one of the most important tests for time series diagnostics and model selection. The Hassani SACF (Sum of the Sample Autocorrelation Function) Theorem , however, indicates that the sum of sample autocorrelation function is always fix for any stationary time series with arbitrary length. This package confirms for sensitivity of the Ljung-Box test to the number of lags involved in the test and therefore it should be used with extra caution. The Hassani SACF Theorem has been described in : Hassani, Yeganegi and M. R. (2019) <doi:10.1016/j.physa.2018.12.028>.

This package performs multiple hot-deck imputation of categorical and continuous variables in a data frame.

Work with model files (setup, input, output) from the hydrological catchment model HYPE: Streamlined file import and export, standard evaluation plot routines, diverse post-processing and aggregation routines for hydrological model analysis. The HYPEtools package is also archived at <doi:10.5281/zenodo.7627955> and can be cited in publications with Brendel et al. (2024) <doi:10.1016/j.envsoft.2024.106094>.

This package implements hierarchically regularized entropy balancing proposed by Xu and Yang (2022) <doi:10.1017/pan.2022.12>. The method adjusts the covariate distributions of the control group to match those of the treatment group. hbal automatically expands the covariate space to include higher order terms and uses cross-validation to select variable penalties for the balancing conditions.

This package implements the method developed by Cao and Kosorok (2011) for the significance analysis of thousands of features in high-dimensional biological studies. It is an asymptotically valid data-driven procedure to find critical values for rejection regions controlling the k-familywise error rate, false discovery rate, and the tail probability of false discovery proportion.

Built by Hodges lab members for current and future Hodges lab members. Other individuals are welcome to use as well. Provides useful functions that the lab uses everyday to analyze various genomic datasets. Critically, only general use functions are provided; functions specific to a given technique are reserved for a separate package. As the lab grows, we expect to continue adding functions to the package to build on previous lab members code.

Base R's default setting for stringsAsFactors within data.frame() and as.data.frame() is supposedly the most often complained about piece of code in the R infrastructure. The hellno package provides an explicit solution without changing R itself or having to mess around with options. It tries to solve this problem by providing alternative data.frame() and as.data.frame() functions that are in fact simple wrappers around base R's data.frame() and as.data.frame() with stringsAsFactors option set to HELLNO ( which in turn equals FALSE ) by default.

This package implements the high-dimensional two-sample test proposed by Zhang (2019) <http://hdl.handle.net/2097/40235>. It also implements the test proposed by Srivastava, Katayama, and Kano (2013) <doi:10.1016/j.jmva.2012.08.014>. These tests are particularly suitable to high dimensional data from two populations for which the classical multivariate Hotelling's T-square test fails due to sample sizes smaller than dimensionality. In this case, the ZWL and ZWLm tests proposed by Zhang (2019) <http://hdl.handle.net/2097/40235>, referred to as zwl_test() in this package, provide a reliable and powerful test.

This package provides a method for identifying responses to experimental stimulation in mass or flow cytometry that uses high dimensional analysis of measured parameters and can be performed with an end-to-end unsupervised approach. In the context of in vitro stimulation assays where high-parameter cytometry was used to monitor intracellular response markers, using cell populations annotated either through automated clustering or manual gating for a combined set of stimulated and unstimulated samples, HDStIM labels cells as responding or non-responding. The package also provides auxiliary functions to rank intracellular markers based on their contribution to identifying responses and generating diagnostic plots.

Converts among many citation formats, including BibTeX', Citeproc', Codemeta', RDF XML', RIS', Schema.org', and Citation File Format'. A low level R6 class is provided, as well as stand-alone functions for each citation format for both read and write.

The classical Markowitz's mean-variance portfolio formulation ignores heavy tails and skewness. High-order portfolios use higher order moments to better characterize the return distribution. Different formulations and fast algorithms are proposed for high-order portfolios based on the mean, variance, skewness, and kurtosis. The package is based on the papers: R. Zhou and D. P. Palomar (2021). "Solving High-Order Portfolios via Successive Convex Approximation Algorithms." <arXiv:2008.00863>. X. Wang, R. Zhou, J. Ying, and D. P. Palomar (2022). "Efficient and Scalable High-Order Portfolios Design via Parametric Skew-t Distribution." <arXiv:2206.02412>.

This model divides coefficients into three types, i.e., local fixed effects, global fixed effects, and random effects (Hu et al., 2022)<doi:10.1177/23998083211063885>. If data have spatial hierarchical structures (especially are overlapping on some locations), it is worth trying this model to reach better fitness.

Most common exact, asymptotic and resample based tests are provided for testing the homogeneity of variances of k normal distributions under normality. These tests are Barlett, Bhandary & Dai, Brown & Forsythe, Chang et al., Gokpinar & Gokpinar, Levene, Liu and Xu, Gokpinar. Also, a data generation function from multiple normal distribution is provided using any multiple normal parameters. Bartlett, M. S. (1937) <doi:10.1098/rspa.1937.0109> Bhandary, M., & Dai, H. (2008) <doi:10.1080/03610910802431011> Brown, M. B., & Forsythe, A. B. (1974).<doi:10.1080/01621459.1974.10482955> Chang, C. H., Pal, N., & Lin, J. J. (2017) <doi:10.1080/03610918.2016.1202277> Gokpinar E. & Gokpinar F. (2017) <doi:10.1080/03610918.2014.955110> Liu, X., & Xu, X. (2010) <doi:10.1016/j.spl.2010.05.017> Levene, H. (1960) <https://cir.nii.ac.jp/crid/1573950400526848896> Gökpınar, E. (2020) <doi:10.1080/03610918.2020.1800037>.