This package implements Individual Conditional Expectation (ICE) plots, a tool for visualizing the model estimated by any supervised learning algorithm. ICE plots refine Friedman's partial dependence plot by graphing the functional relationship between the predicted response and a covariate of interest for individual observations. Specifically, ICE plots highlight the variation in the fitted values across the range of a covariate of interest, suggesting where and to what extent they may exist.

Implementation of analytical and sampling-based power analyses for the Wald, likelihood ratio (LR), score, and gradient tests. Can be applied to item response theory (IRT) models that are fitted using marginal maximum likelihood estimation. The methods are described in our paper (Zimmer et al. (2022) <doi:10.1007/s11336-022-09883-5>).

This package provides examples of code for analyzing data or accomplishing tasks that may be useful to institutional or educational researchers.

An R package for inferring cell-type specific gene regulatory network from single-cell RNA-seq data.

Allows the construction selection indices based on estimated breeding values in animal and plant breeding and to calculate several analytic measures around to assess its impact on genetic and phenotypic progress. The methodology thereby allows to analyze genetic gain of traits in the breeding goal which are not part of the actual index and automatically computes several analytic measures. It further allows to retrospectively derive realized economic weights from observed genetic trends. The framework is described in Simianer, H., Heise, J., Rensing, S., Pook, T. Geibel, J. and Reimer, C. (2023) <doi:10.1186/s12711-023-00807-0>.

Based on large margin principle, this package performs feature selection methods: "IM4E"(Iterative Margin-Maximization under Max-Min Entropy Algorithm); "Immigrate"(Iterative Max-Min Entropy Margin-Maximization with Interaction Terms Algorithm); "BIM"(Boosted version of IMMIGRATE algorithm); "Simba"(Iterative Search Margin Based Algorithm); "LFE"(Local Feature Extraction Algorithm). This package also performs prediction for the above feature selection methods.

This package provides a toolkit that allows scientists to work with data from single cell sequencing technologies such as scRNA-seq, scVDJ-seq, scATAC-seq, CITE-Seq and Spatial Transcriptomics (ST). Single (i) Cell R package ('iCellR') provides unprecedented flexibility at every step of the analysis pipeline, including normalization, clustering, dimensionality reduction, imputation, visualization, and so on. Users can design both unsupervised and supervised models to best suit their research. In addition, the toolkit provides 2D and 3D interactive visualizations, differential expression analysis, filters based on cells, genes and clusters, data merging, normalizing for dropouts, data imputation methods, correcting for batch differences, pathway analysis, tools to find marker genes for clusters and conditions, predict cell types and pseudotime analysis. See Khodadadi-Jamayran, et al (2020) <doi:10.1101/2020.05.05.078550> and Khodadadi-Jamayran, et al (2020) <doi:10.1101/2020.03.31.019109> for more details.

We use the ISR to handle with PCA-based missing data with high correlation, and the DISR to handle with distributed PCA-based missing data. The philosophy of the package is described in Guo G. (2024) <doi:10.1080/03610918.2022.2091779>.

We consider studies in which information from error-prone diagnostic tests or self-reports are gathered sequentially to determine the occurrence of a silent event. Using a likelihood-based approach incorporating the proportional hazards assumption, we provide functions to estimate the survival distribution and covariate effects. We also provide functions for power and sample size calculations for this setting. Please refer to Xiangdong Gu, Yunsheng Ma, and Raji Balasubramanian (2015) <doi: 10.1214/15-AOAS810>, Xiangdong Gu and Raji Balasubramanian (2016) <doi: 10.1002/sim.6962>, Xiangdong Gu, Mahlet G Tadesse, Andrea S Foulkes, Yunsheng Ma, and Raji Balasubramanian (2020) <doi: 10.1186/s12911-020-01223-w>.

This is an Automatic Item Generator for Psychological Assessment. Items created with the IMak package should not be used in applied settings as part of the working protocol without ensuring first that the items meet the required psychometric quality standards (see Blum & Holling, 2018) <DOI:10.3389/fpsyg.2018.01286>.

This package provides a toolbox for constructing potential landscapes for Ising networks. The parameters of the networks can be directly supplied by users or estimated by the IsingFit package by van Borkulo and Epskamp (2016) <https://CRAN.R-project.org/package=IsingFit> from empirical data. The Ising model's Boltzmann distribution is preserved for the potential landscape function. The landscape functions can be used for quantifying and visualizing the stability of network states, as well as visualizing the simulation process.

Drawing statistical inference on the coefficients of a short- or long-horizon predictive regression with persistent regressors by using the IVX method of Magdalinos and Phillips (2009) <doi:10.1017/S0266466608090154> and Kostakis, Magdalinos and Stamatogiannis (2015) <doi:10.1093/rfs/hhu139>.

Some tools to assist with converting International Organization for Standardization (ISO) standard 11784 (ISO11784) animal ID codes between 4 recognised formats commonly displayed on Passive Integrated Transponder (PIT) tag readers. The most common formats are 15 digit decimal, e.g., 999123456789012, and 13 character hexadecimal dot format, e.g., 3E7.1CBE991A14. These are referred to in this package as isodecimal and isodothex. The other two formats are the raw hexadecimal representation of the ISO11784 binary structure (see <https://en.wikipedia.org/wiki/ISO_11784_and_ISO_11785>). There are two flavours of this format, a left and a right variation. Which flavour a reader happens to output depends on if the developers decided to reverse the binary number or not before converting to hexadecimal, a decision based on the fact that the PIT tags will transmit their binary code Least Significant Bit (LSB) first, or backwards basically.

Interpreting the differences between mean scale scores across various forms of an assessment can be challenging. This difficulty arises from different mappings between raw scores and scale scores, complex mathematical relationships, adjustments based on judgmental procedures, and diverse equating functions applied to different assessment forms. An alternative method involves running simulations to explore the effect of incrementing raw scores on mean scale scores. The idmact package provides an implementation of this approach based on the algorithm detailed in Schiel (1998) <https://www.act.org/content/dam/act/unsecured/documents/ACT_RR98-01.pdf> which was developed to help interpret differences between mean scale scores on the American College Testing (ACT) assessment. The function idmact_subj() within the package offers a framework for running simulations on subject-level scores. In contrast, the idmact_comp() function provides a framework for conducting simulations on composite scores.

Currently used CI method has its limitation when the test statistics are asymmetrical (chi-square test, F-test) or the model functions are non-linear. It can be overcome by using the likelihood functions for the interval estimation. inteli package now supports interval estimation for the mean, variance, variance ratio, binomial distribution, Poisson distribution, odds ratio, risk difference, relative risk and their likelihood function plots. Testing functions are also provided.

SQL back-end to dplyr for Apache Impala, the massively parallel processing query engine for Apache Hadoop'. Impala enables low-latency SQL queries on data stored in the Hadoop Distributed File System (HDFS)', Apache HBase', Apache Kudu', Amazon Simple Storage Service (S3)', Microsoft Azure Data Lake Store (ADLS)', and Dell EMC Isilon'. See <https://impala.apache.org> for more information about Impala.

Currently using the proportional hazards (PH) model. More methods under other semiparametric regression models will be included in later versions.

This package provides user-friendly functions for programmatic access to macroeconomic data from the International Monetary Fund's SDMX 3.0 IMF Data API <https://data.imf.org/en/Resource-Pages/IMF-API>.

R dependency injection framework. Dependency injection allows a program design to follow the dependency inversion principle. The user delegates to external code (the injector) the responsibility of providing its dependencies. This separates the responsibilities of use and construction.

Facilitates fitting measurement error and missing data imputation models using integrated nested Laplace approximations, according to the method described in Skarstein, Martino and Muff (2023) <doi:10.1002/bimj.202300078>. See Skarstein and Muff (2024) <doi:10.48550/arXiv.2406.08172> for details on using the package.

Simulation of segments shared identical-by-descent (IBD) by pedigree members. Using sex specific recombination rates along the human genome (Halldorsson et al. (2019) <doi:10.1126/science.aau1043>), phased chromosomes are simulated for all pedigree members. Applications include calculation of realised relatedness coefficients and IBD segment distributions. ibdsim2 is part of the pedsuite collection of packages for pedigree analysis. A detailed presentation of the pedsuite', including a separate chapter on ibdsim2', is available in the book Pedigree analysis in R (Vigeland, 2021, ISBN:9780128244302). A Shiny app for visualising and comparing IBD distributions is available at <https://magnusdv.shinyapps.io/ibdsim2-shiny/>.

Calculate false ring proportions from data frames of intra annual density fluctuations.

This package provides tools for estimating uncertainty in individual polygenic risk scores (PRSs) using both sampling-based and analytical methods, as well as the Best Linear Unbiased Estimator (BLUE). These methods quantify variability in PRS estimates for both binary and quantitative traits. See Henderson (1975) <doi:10.2307/2529430> for more details.

Calculation of key bacterial growth curve parameters using fourth degree polynomial functions. Six growth curve parameters are provided including peak growth rate, doubling time, lag time, maximum growth, and etc. ipolygrowth takes time series data from individual biological samples (with technical replicates) or multiple samples.