Send emails using the mailgun api. To use this package you will need an account from <https://www.mailgun.com> .

Implementation of icosahedral grids in three dimensions. The spherical-triangular tessellation can be set to create grids with custom resolutions. Both the primary triangular and their inverted penta-hexagonal grids can be calculated. Additional functions are provided that allow plotting of the grids and associated data, the interaction of the grids with other raster and vector objects, and treating the grids as a graphs.

This package provides a toolkit that allows scientists to work with data from single cell sequencing technologies such as scRNA-seq, scVDJ-seq, scATAC-seq, CITE-Seq and Spatial Transcriptomics (ST). Single (i) Cell R package ('iCellR') provides unprecedented flexibility at every step of the analysis pipeline, including normalization, clustering, dimensionality reduction, imputation, visualization, and so on. Users can design both unsupervised and supervised models to best suit their research. In addition, the toolkit provides 2D and 3D interactive visualizations, differential expression analysis, filters based on cells, genes and clusters, data merging, normalizing for dropouts, data imputation methods, correcting for batch differences, pathway analysis, tools to find marker genes for clusters and conditions, predict cell types and pseudotime analysis. See Khodadadi-Jamayran, et al (2020) <doi:10.1101/2020.05.05.078550> and Khodadadi-Jamayran, et al (2020) <doi:10.1101/2020.03.31.019109> for more details.

This package provides a voxel is a representation of a value on a regular, three-dimensional grid; it is the 3D equivalent of a 2D pixel. Voxel data can be visualised with this package using fixed viewpoint isometric cubes for each data point. This package also provides sample voxel data and tools for transforming the data.

This package provides a dataframe validation framework for package builders who use dataframes as function parameters. It performs checks on column names, coerces data-types, and checks grouping to make sure user inputs conform to a specification provided by the package author. It provides a mechanism for package authors to automatically document supported dataframe inputs and selectively dispatch to functions depending on the format of a dataframe much like S3 does for classes. It also contains some developer tools to make working with and documenting dataframe specifications easier. It helps package developers to improve their documentation and simplifies parameter validation where dataframes are used as function parameters.

Dichotomous and polytomous data analysis and their scoring using the unidimensional Item Response Theory model (Chalmers (2012) <doi:10.18637/jss.v048.i06>) with user-friendly graphic User Interface. Suitable for beginners who are learning item response theory.

IsoSpec is a fine structure calculator used for obtaining the most probable masses of a chemical compound given the frequencies of the composing isotopes and their masses. It finds the smallest set of isotopologues with a given probability. The probability is assumed to be that of the product of multinomial distributions, each corresponding to one particular element and parametrized by the frequencies of finding these elements in nature. These numbers are supplied by IUPAC - the International Union of Pure and Applied Chemistry. See: Lacki, Valkenborg, Startek (2020) <DOI:10.1021/acs.analchem.0c00959> and Lacki, Startek, Valkenborg, Gambin (2017) <DOI:10.1021/acs.analchem.6b01459> for the description of the algorithms used.

An eclectic collection of short stories and poetry with topics on climate strange, connecting the geopolitical dots, the myth of us versus them, and the idiocy of war. Please refer to the COPYRIGHTS file and the text_citation.cff file for the reference copyright information and for the complete citations of the reference sources, respectively.

Algorithms and utility functions for indoor positioning using fingerprinting techniques. These functions are designed for manipulation of RSSI (Received Signal Strength Intensity) data sets, estimation of positions,comparison of the performance of different models, and graphical visualization of data. Machine learning algorithms and methods such as k-nearest neighbors or probabilistic fingerprinting are implemented in this package to perform analysis and estimations over RSSI data sets.

Relocates oversampled data from a specific oversampling method to cover area determined by pure and proper class cover catch digraphs (PCCCD). It prevents any data to be generated in class overlapping area. For more details, see the corresponding publication: F. SaÄ lam (2025) <doi:10.1007/s10994-025-06755-8>.

Reproducible, programmatic retrieval of datasets from the Inter-university Consortium for Political and Social Research archive.

This is the central location for data and tools for the development, maintenance, analysis, and deployment of the International Soil Radiocarbon Database (ISRaD). ISRaD was developed as a collaboration between the U.S. Geological Survey Powell Center and the Max Planck Institute for Biogeochemistry. This R package provides tools for accessing and manipulating ISRaD data, compiling local data using the ISRaD data structure, and simple query and reporting functions for ISRaD. For more detailed information visit the ISRaD website at: <https://soilradiocarbon.org/>.

This toolbox makes working with oxygen, carbon, and clumped isotope data reproducible and straightforward. Use it to quickly calculate isotope fractionation factors, and apply paleothermometry equations.

This package provides function to read data from the Igor Pro data analysis program by Wavemetrics'. The data formats supported are Igor packed experiment format ('pxp') and Igor binary wave ('ibw'). See: <https://www.wavemetrics.com/> for details. Also includes functions to load special pxp files produced by the Igor Pro Neuromatic and Nclamp packages for recording and analysing neuronal data. See <https://github.com/SilverLabUCL/NeuroMatic> for details.

Identity by Descent (IBD) distributions in pedigrees. A Hidden Markov Model is used to compute identity coefficients, simulate IBD segments and to derive the distribution of total IBD sharing and segment count across chromosomes. The methods are applied in Kruijver (2025) <doi:10.3390/genes16050492>. The probability that the total IBD sharing is zero can be computed using the method of Donnelly (1983) <doi:10.1016/0040-5809(83)90004-7>.

This package implements a Shiny Item Analysis module and functions for computing false positive rate and other binary classification metrics from inter-rater reliability based on Bartoš & Martinková (2024) <doi:10.1111/bmsp.12343>.

Multivariate Expectation-Maximization (EM) based imputation framework that offers several different algorithms. These include regularisation methods like Lasso and Ridge regression, tree-based models and dimensionality reduction methods like PCA and PLS.

Interesting igraph datasets from Melanie Walsh's sample social network datasets repository <https://github.com/melaniewalsh/sample-social-network-datasets>.

This package provides a collection of useful functions and datasets for the Data Science Course at IBAW.

This package provides a method to integrate molecular profiles of cancer patients (gene copy number and mRNA abundance) to identify candidate gain of function alterations. These candidate alterations can be subsequently further tested to discover cancer driver alterations. Briefly, this method tests of genomic correlates of mRNA dysregulation and prioritise those where DNA gains/amplifications are associated with elevated mRNA expression of the same gene. For details see, Haider S et al. (2016) "Genomic alterations underlie a pan-cancer metabolic shift associated with tumour hypoxia", Genome Biology, <https://pubmed.ncbi.nlm.nih.gov/27358048/>.

Fits large-scale regression models with a penalty that restricts the maximum number of non-zero regression coefficients to a prespecified value. While Chu et al (2020) <doi:10.1093/gigascience/giaa044> describe the basic algorithm, this package uses Cyclops for an efficient implementation.

Download data from ISTAT (Italian Institute of Statistics) database, both old and new provider (respectively, <http://dati.istat.it/> and <https://esploradati.istat.it/databrowser/>). Additional functions for manipulating data are provided. Moreover, a shiny application called shinyIstat can be used to search, download and filter datasets more easily.

Generates three inter-related genomic datasets: methylation, gene expression and protein expression having user specified cluster patterns. The simulation utilizes the realistic inter- and intra- relationships from real DNA methylation, mRNA expression and protein expression data from the TCGA ovarian cancer study, Chalise (2016) <doi:10.1016/j.cmpb.2016.02.011>.

An R client for the iplookupapi.com IP Lookup API. The API requires registration of an API key. Basic features are free, some require a paid subscription. You can find the full API documentation at <https://iplookupapi.com/docs> .