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Carries out integrative clustering analysis using multiple types of genomic dataset using integrative Non-negative Matrix factorization.
Data from the United States Center for Medicare and Medicaid Services (CMS) is included in this package. There are ICD-9 and ICD-10 diagnostic and procedure codes, and lists of the chapter and sub-chapter headings and the ranges of ICD codes they encompass. There are also two sample datasets. These data are used by the icd package for finding comorbidities.
An implementation of the iterative bootstrap procedure of Kuk (1995) <doi:10.1111/j.2517-6161.1995.tb02035.x> to correct the estimation bias of a fitted model object. This procedure has better bias correction properties than the bootstrap bias correction technique.
Compute several variations of the Implicit Association Test (IAT) scores, including the D scores (Greenwald, Nosek, Banaji, 2003, <doi:10.1037/0022-3514.85.2.197>) and the new scores that were developed using robust statistics (Richetin, Costantini, Perugini, and Schonbrodt, 2015, <doi:10.1371/journal.pone.0129601>).
This package produces a publication-ready table that includes all effect estimates necessary for full reporting effect modification and interaction analysis as recommended by Knol and Vanderweele (2012) [<doi:10.1093/ije/dyr218>]. It also estimates confidence interval for the trio of additive interaction measures using the delta method (see Hosmer and Lemeshow (1992), [<doi:10.1097/00001648-199209000-00012>]), variance recovery method (see Zou (2008), [<doi:10.1093/aje/kwn104>]), or percentile bootstrapping (see Assmann et al. (1996), [<doi:10.1097/00001648-199605000-00012>]).
Fitting and validation of machine learning algorithms for volume prediction of trees, currently for conifer trees based on diameter at breast height and height as explanatory variables.
This package provides a toolkit that allows scientists to work with data from single cell sequencing technologies such as scRNA-seq, scVDJ-seq, scATAC-seq, CITE-Seq and Spatial Transcriptomics (ST). Single (i) Cell R package ('iCellR') provides unprecedented flexibility at every step of the analysis pipeline, including normalization, clustering, dimensionality reduction, imputation, visualization, and so on. Users can design both unsupervised and supervised models to best suit their research. In addition, the toolkit provides 2D and 3D interactive visualizations, differential expression analysis, filters based on cells, genes and clusters, data merging, normalizing for dropouts, data imputation methods, correcting for batch differences, pathway analysis, tools to find marker genes for clusters and conditions, predict cell types and pseudotime analysis. See Khodadadi-Jamayran, et al (2020) <doi:10.1101/2020.05.05.078550> and Khodadadi-Jamayran, et al (2020) <doi:10.1101/2020.03.31.019109> for more details.
It provides a generic set of tools for initializing a synthetic population with each individual in specific disease states, and making transitions between those disease states according to the rates calculated on each timestep. The new version 1.0.0 has C++ code integration to make the functions run faster. It has also a higher level function to actually run the transitions for the number of timesteps that users specify. Additional functions will follow for changing attributes on demographic, health belief and movement.
Perform fast and memory efficient time-weighted averaging of values measured over intervals into new arbitrary intervals. This package is useful in the context of data measured or represented as constant values over intervals on a one-dimensional discrete axis (e.g. time-integrated averages of a curve over defined periods). This package was written specifically to deal with air pollution data recorded or predicted as averages over sampling periods. Data in this format often needs to be shifted to non-aligned periods or averaged up to periods of longer duration (e.g. averaging data measured over sequential non-overlapping periods to calendar years).
Fits Bayesian hierarchical models of vaccine coverage by location, birth cohort, and age. Observations of vaccination status (which may span cohorts, ages, and doses) are used to fit a latent survival-style process model that decomposes coverage into a lifetime propensity to vaccinate and a time-varying force of vaccination. Hierarchical spatial structure (e.g., state, county, school) supports partial pooling via random effects. Models are implemented in Stan and fit via rstan'. Provides helpers to validate user-supplied input data, and to predict coverage from fitted models.
This package provides a function and vignettes for computing an intraclass correlation described in Aguinis & Culpepper (2015) <doi:10.1177/1094428114563618>. This package quantifies the share of variance in a dependent variable that is attributed to group heterogeneity in slopes.
Currently used CI method has its limitation when the test statistics are asymmetrical (chi-square test, F-test) or the model functions are non-linear. It can be overcome by using the likelihood functions for the interval estimation. inteli package now supports interval estimation for the mean, variance, variance ratio, binomial distribution, Poisson distribution, odds ratio, risk difference, relative risk and their likelihood function plots. Testing functions are also provided.
Suite of functions that help simulate elections under different electoral systems, which are then used to compute incentives generated by these systems in terms of the inter- and intra-party dimensions of electoral competition.
Calculates insulin secretion rates from C-peptide values based on the methods described in Van Cauter et al. (1992) <doi:10.2337/diab.41.3.368>. Includes functions to calculate estimated insulin secretion rates using linear or cubic spline interpolation of c-peptide values (see Eaton et al., 1980 <doi:10.1210/jcem-51-3-520> and Polonsky et al., 1986 <doi:10.1172/JCI112308>) and to calculate estimates of input coefficients (volume of distribution, short half life, long half life, and fraction attributed to short half life) as described by Van Cauter. Although the generated coefficients are specific to insulin secretion, the two-compartment secretion model used here is useful for certain applications beyond insulin.
Computes and decomposes Gini, Bonferroni and Zenga 2007 point and synthetic concentration indexes. Decompositions are intended: by sources, by subpopulations and by sources and subpopulations jointly. References, Zenga M. M.(2007) <doi:10.1400/209575> Zenga M. (2015) <doi:10.1400/246627> Zenga M., Valli I. (2017) <doi:10.26350/999999_000005> Zenga M., Valli I. (2018) <doi:10.26350/999999_000011>.
Convert files to and from IDX format to vectors, matrices and arrays. IDX is a very simple file format designed for storing vectors and multidimensional matrices in binary format. The format is described on the website from Yann LeCun <http://yann.lecun.com/exdb/mnist/>.
An implementation of Ichimoku Kinko Hyo', also commonly known as cloud charts. Static and interactive visualizations with tools for creating, backtesting and development of quantitative ichimoku strategies. As described in Sasaki (1996, ISBN:4925152009), the technique is a refinement on candlestick charting, originating from Japan and now in widespread use in technical analysis worldwide. Translating as one-glance equilibrium chart, it allows the price action and market structure of financial securities to be determined at-a-glance. Incorporates an interface with the OANDA fxTrade API <https://developer.oanda.com/> for retrieving historical and live streaming price data for major currencies, metals, commodities, government bonds and stock indices.
Creation of tables of summary statistics or counts for clinical data (for TLFs'). These tables can be exported as in-text table (with the flextable package) for a Clinical Study Report (Word format) or a topline presentation (PowerPoint format), or as interactive table (with the DT package) to an html document for clinical data review.
This package implements imputation methods using EM and Data Augmentation for multinomial data following the work of Schafer 1997 <ISBN: 978-0-412-04061-0>.
It provides multiple functions that are useful for ecological research and teaching statistics to ecologists. It is based on data analysis courses offered at the Instituto de Ecologà a AC (INECOL). For references and published evidence see, Manrique-Ascencio, et al (2024) <doi:10.1111/gcb.17282>, Manrique-Ascencio et al (2024) <doi:10.1111/plb.13683>, Ruiz-Guerra et al(2017) <doi:10.17129/botsci.812>, Juarez-Fragoso et al (2024) <doi:10.1007/s10980-024-01809-z>, Papaqui-Bello et al (2024) <doi:10.13102/sociobiology.v71i2.10503>.
This package provides a toolbox for constructing potential landscapes for Ising networks. The parameters of the networks can be directly supplied by users or estimated by the IsingFit package by van Borkulo and Epskamp (2016) <https://CRAN.R-project.org/package=IsingFit> from empirical data. The Ising model's Boltzmann distribution is preserved for the potential landscape function. The landscape functions can be used for quantifying and visualizing the stability of network states, as well as visualizing the simulation process.
This package provides tools for passing messages between R processes. Shiny examples are provided showing how to perform useful tasks such as: updating reactive values from within a future, progress bars for long running async tasks, and interrupting async tasks based on user input.
This package provides a simple wrapper around the ical.js library executing Javascript code via V8 (the Javascript engine driving the Chrome browser and Node.js and accessible via the V8 R package). This package enables users to parse iCalendar files ('.ics', .ifb', .iCal', .iFBf') into lists and data.frames to ultimately do statistics on events, meetings, schedules, birthdays, and the like.
This package contains several tools to treat imaging flow cytometry data from ImageStream® and FlowSight® cytometers ('Amnis® Cytek®'). Provides an easy and simple way to read and write .fcs, .rif, .cif and .daf files. Information such as masks, features, regions and populations set within these files can be retrieved for each single cell. In addition, raw data such as images stored can also be accessed. Users, may hopefully increase their productivity thanks to dedicated functions to extract, visualize, manipulate and export IFC data. Toy data example can be installed through the IFCdata package of approximately 32 MB, which is available in a drat repository <https://gitdemont.github.io/IFCdata/>. See file COPYRIGHTS and file AUTHORS for a list of copyright holders and authors.