This package provides a toolbox for programming Clinical Data Standards Interchange Consortium (CDISC) compliant Analysis Data Model (ADaM) datasets in R. ADaM datasets are a mandatory part of any New Drug or Biologics License Application submitted to the United States Food and Drug Administration (FDA). Analysis derivations are implemented in accordance with the "Analysis Data Model Implementation Guide" (CDISC Analysis Data Model Team, 2021, <https://www.cdisc.org/standards/foundational/adam>). The package is an extension package of the admiral package for pediatric clinical trials.

Interactive graphical user interface (GUI) for the package AdhereR', allowing the user to access different data sources, to explore the patterns of medication use therein, and the computation of various measures of adherence. It is implemented using Shiny and HTML/CSS/JavaScript.

Functions, data sets and examples for the calculation of various indices of biodiversity including species, functional and phylogenetic diversity. Part of the indices are expressed in terms of equivalent numbers of species. The package also provides ways to partition biodiversity across spatial or temporal scales (alpha, beta, gamma diversities). In addition to the quantification of biodiversity, ordination approaches are available which rely on diversity indices and allow the detailed identification of species, functional or phylogenetic differences between communities.

Generates data for challenging machine learning models in Arena <https://arena.drwhy.ai> - an interactive web application. You can start the server with XAI (Explainable Artificial Intelligence) plots to be generated on-demand or precalculate and auto-upload data file beside shareable Arena URL.

This package provides an easy to use unified interface for creating validation plots for any model. The auditor helps to avoid repetitive work consisting of writing code needed to create residual plots. This visualizations allow to asses and compare the goodness of fit, performance, and similarity of models.

This package implements two complementary high-dimensional feature screening methods, Adaptive Iterative Ridge High-dimensional Ordinary Least-squares Projection (Air-HOLP, suitable when the number of predictors p is greater than or equal to the sample size n) and Adaptive Iterative Ridge Ordinary Least Squares (Air-OLS, for n greater than p). Also provides helper functions to generate compound-symmetry and AR(1) correlated data, plus a unified Air() front end and a summary method. For methodological details see Joudah, Muller and Zhu (2025) <doi:10.1007/s11222-025-10599-6>.

Interface to the Azure Machine Learning Software Development Kit ('SDK'). Data scientists can use the SDK to train, deploy, automate, and manage machine learning models on the Azure Machine Learning service. To learn more about Azure Machine Learning visit the website: <https://docs.microsoft.com/en-us/azure/machine-learning/service/overview-what-is-azure-ml>.

This package provides R bindings to the Automerge Conflict-free Replicated Data Type ('CRDT') library. Automerge enables automatic merging of concurrent changes without conflicts, making it ideal for distributed systems, collaborative applications, and offline-first architectures. The approach of local-first software was proposed in Kleppmann, M., Wiggins, A., van Hardenberg, P., McGranaghan, M. (2019) <doi:10.1145/3359591.3359737>. This package supports all Automerge data types (maps, lists, text, counters) and provides both low-level and high-level synchronization protocols for seamless interoperability with JavaScript and other Automerge implementations.

An interface to the AutoDesk Platform Services ('APS') API including the Authentication API for obtaining OAuth2 tokens with expiry tracking, Data Management API for managing buckets and objects across the platform's cloud services, Design Automation API for running automated tasks on design files in the cloud, Model Derivative API for translating design files into SVF', SVF2', OBJ', and STL formats and extracting model data, Reality Capture API for generating 3D models from photogrammetry image sets, and Viewer for rendering 2D and 3D models in Shiny applications.

This package implements cubic regularization methods (ARC) for local optimization problems common in statistics and applied research. Provides robust handling of ill-conditioned, nonconvex, and indefinite Hessian problems with automatic saddle point escape. Supports box constraints; linear equality constraints are planned for a future release.

Spatial modeling of energy balance and actual evapotranspiration using satellite images and meteorological data. Options of satellite are: Landsat-8 (with and without thermal bands), Sentinel-2 and MODIS. Respectively spatial resolutions are 30, 100, 10 and 250 meters. User can use data from a single meteorological station or a grid of meteorological stations (using any spatial interpolation method). Silva, Teixeira, and Manzione (2019) <doi:10.1016/j.envsoft.2019.104497>.

This package provides functions to convert origin-destination data, represented as straight desire lines in the sf Simple Features class system, into JSON files that can be directly imported into A/B Street <https://www.abstreet.org>, a free and open source tool for simulating urban transport systems and scenarios of change <doi:10.1007/s10109-020-00342-2>.

Visualization of antibody titer scores is valuable for examination of vaccination effects. AntibodyTiters visualizes antibody titers of all or selected patients. This package also produces empty excel files in a specified format, in which users can fill in experimental data for visualization. Excel files with toy data can also be produced, so that users can see how it is visualized before obtaining real data. The data should contain titer scores at pre-vaccination, after-1st shot, after-2nd shot, and at least one additional sampling points. Patients with missing values can be included. The first two sampling points (pre-vaccination and after-1st shot) will be plotted discretely, whereas those following will be plotted on a continuous time scale that starts from the day of second shot. Half-life of titer can also be calculated for each pair of sampling points.

Add-on for arules to handle and mine frequent sequences. Provides interfaces to the C++ implementation of cSPADE by Mohammed J. Zaki.

This package provides a Tool for Semi-Automating the Statistical Disclosure Control of Research Outputs.

Create Tables for Reporting Clinical Trials. Calculates descriptive statistics and hypothesis tests, arranges the results in a table ready for reporting with LaTeX, HTML or Word.

Create aliases for other R names or arbitrarily complex R expressions. Accessing the alias acts as-if the aliased expression were invoked instead, and continuously reflects the current value of that expression: updates to the original expression will be reflected in the alias; and updates to the alias will automatically be reflected in the original expression.

Different tools for managing databases of airborne particles, elaborating the main calculations and visualization of results. In a first step, data are checked using tools for quality control and all missing gaps are completed. Then, the main parameters of the pollen season are calculated and represented graphically. Multiple graphical tools are available: pollen calendars, phenological plots, time series, tendencies, interactive plots, abundance plots...

This package provides adaptive direct sparse regression for high-dimensional multimodal data with heterogeneous missing patterns and measurement errors. AdapDISCOM extends the DISCOM framework with modality-specific adaptive weighting to handle varying data structures and error magnitudes across blocks. The method supports flexible block configurations (any K blocks) and includes robust variants for heavy-tailed distributions ('AdapDISCOM'-Huber) and fast implementations for large-scale applications (Fast-'AdapDISCOM'). Designed for realistic multimodal scenarios where different data sources exhibit distinct missing data patterns and contamination levels. Diakité et al. (2025) <doi:10.48550/arXiv.2508.00120>.

This package provides actuarial modeling tools for Monte Carlo loss simulations, loss reserving, and reinsurance layer loss calculations. It enables users to generate stochastic loss datasets with customisable frequency and severity distributions, fit development patterns to claim triangles, and calculate reinsurance losses for occurrence and aggregate layers with user-defined retentions, limits, and reinstatements. For development pattern selection, the package includes a machine learning approach that evaluates multiple reserving models using holdout validation to identify the best-fitting pattern based on predictive accuracy, this is based on the algorithm described in Richman, R and Balona, C (2020)<https://www.ssrn.com/abstract=3697256>.

This package provides a novel parametrization of log transformation and a shift parameter to automate the transformation process are proposed in R package AutoTransQF based on Feng et al. (2016). Please read Feng et al. (2016) <doi:10.1002/sta4.104> for more details of the method.

This package provides simple and intuitive functions for basic statistical analyses. Methods include the t-test (Student 1908 <doi:10.1093/biomet/6.1.1>), the Mann-Whitney U test (Mann and Whitney 1947 <doi:10.1214/aoms/1177730491>), Pearson's correlation (Pearson 1895 <doi:10.1098/rspl.1895.0041>), and analysis of variance (Fisher 1925, <doi:10.1007/978-1-4612-4380-9_5>). Functions are compatible with ggplot2 and dplyr'.

This package implements several exact methods for allocating optimal sample sizes when designing stratified samples. These methods are discussed in Wright (2012) <doi:10.1080/00031305.2012.733679> and Wright (2017) <doi:10.1016/j.spl.2017.04.026>.

This package implements adaptive gPCA, as described in: Fukuyama, J. (2017) <arXiv:1702.00501>. The package also includes functionality for applying the method to phyloseq objects so that the method can be easily applied to microbiome data and a shiny app for interactive visualization.