This package provides a collection of several utility functions related to binary incomplete block designs. Contains function to generate A- and D-efficient binary incomplete block designs with given numbers of treatments, number of blocks and block size. Contains function to generate an incomplete block design with specified concurrence matrix. There are functions to generate balanced treatment incomplete block designs and incomplete block designs for test versus control treatments comparisons with specified concurrence matrix. Allows performing analysis of variance of data and computing estimated marginal means of factors from experiments using a connected incomplete block design. Tests of hypothesis of treatment contrasts in incomplete block design set up is supported.

This package implements the Interval-Censored Sequence Kernel Association (ICSKAT) test for testing the association between interval-censored time-to-event outcomes and groups of single nucleotide polymorphisms (SNPs). Interval-censored time-to-event data occur when the event time is not known exactly but can be deduced to fall within a given interval. For example, some medical conditions like bone mineral density deficiency are generally only diagnosed at clinical visits. If a patient goes for clinical checkups yearly and is diagnosed at, say, age 30, then the onset of the deficiency is only known to fall between the date of their age 29 checkup and the date of the age 30 checkup. Interval-censored data include right- and left-censored data as special cases. This package also implements the interval-censored Burden test and the ICSKATO test, which is the optimal combination of the ICSKAT and Burden tests. Please see the vignette for a quickstart guide. The paper describing these methods is " Inference for Set-Based Effects in Genetic Association Studies with Interval-Censored Outcomes" by Sun R, Zhu L, Li Y, Yasui Y, & Robison L (Biometrics 2023, <doi:10.1111/biom.13636>).

Derivation of indexes for benchmarking purposes. A methodology with flexible number of constituents is implemented. Also functions for market capitalization and volume weighted indexes with fixed number of constituents are available. The main function of the package, indexComp(), provides the derived index, suitable for analysis purposes. The functions indexUpdate(), indexMemberSelection() and indexMembersUpdate() are components of indexComp() and enable one to construct and continuously update an index, e.g. for display on a website. The methodology behind the functions provided gets introduced in Trimborn and Haerdle (2018) <doi:10.1016/j.jempfin.2018.08.004>.

Kappa statistics is one of the most used methods to evaluate the effectiveness of inpsections based on attribute assessments in industry. However, its estimation by available methods does not provide its "real" or "intrinstic" value. This package provides functions for the computation of the intrinsic kappa value as it is described in: Rafael Sanchez-Marquez, Frank Gerhorst and David Schindler (2023) "Effectiveness of quality inspections of attributive characteristics â A novel and practical method for estimating the â intrinsicâ value of kappa based on alpha and beta statistics." <doi:10.1016/j.cie.2023.109006>.

Relocates oversampled data from a specific oversampling method to cover area determined by pure and proper class cover catch digraphs (PCCCD). It prevents any data to be generated in class overlapping area. For more details, see the corresponding publication: F. SaÄ lam (2025) <doi:10.1007/s10994-025-06755-8>.

Cluster sampling is a valuable approach when constructing a comprehensive list of individual units is challenging. It provides operational and cost advantages. This package is designed to test the efficiency of cluster sampling in terms cluster variance and design effect in context to crop surveys. This package has been developed using the algorithm of Iqbal et al. (2018) <doi:10.19080/BBOAJ.2018.05.555673>.

This package provides tools for estimating uncertainty in individual polygenic risk scores (PRSs) using both sampling-based and analytical methods, as well as the Best Linear Unbiased Estimator (BLUE). These methods quantify variability in PRS estimates for both binary and quantitative traits. See Henderson (1975) <doi:10.2307/2529430> for more details.

This package provides a GUI designed to support the analysis of financial-economic time series data.

Calculate various information criteria in literature for "lm" and "glm" objects.

Estimates the intraclass correlation coefficient for trajectory data using a matrix of distances between trajectories. The distances implemented are the extended Hausdorff distances (Min et al. 2007) <doi:10.1080/13658810601073315> and the discrete Fréchet distance (Magdy et al. 2015) <doi:10.1109/IntelCIS.2015.7397286>.

Offers a pipe-friendly alternative to the dplyr functions case_when() and if_else(), as well as a number of user-friendly simplifications for common use cases. These functions accept a vector as an optional first argument, allowing conditional statements to be built using the magrittr dot operator. The functions also coerce all outputs to the same type, meaning you no longer have to worry about using specific typed variants of NA or explicitly declaring integer outputs, and evaluate outputs somewhat lazily, so you don't waste time on long operations that won't be used.

This package provides tools for passing messages between R processes. Shiny examples are provided showing how to perform useful tasks such as: updating reactive values from within a future, progress bars for long running async tasks, and interrupting async tasks based on user input.

An interface to the algorithms of Interpretable AI <https://www.interpretable.ai> from the R programming language. Interpretable AI provides various modules, including Optimal Trees for classification, regression, prescription and survival analysis, Optimal Imputation for missing data imputation and outlier detection, and Optimal Feature Selection for exact sparse regression. The iai package is an open-source project. The Interpretable AI software modules are proprietary products, but free academic and evaluation licenses are available.

This package provides a collection of functions for working with time series data, including functions for drawing, decomposing, and forecasting. Includes capabilities to compare multiple series and fit both additive and multiplicative models. Used by iNZight', a graphical user interface providing easy exploration and visualisation of data for students of statistics, available in both desktop and online versions. Holt (1957) <doi:10.1016/j.ijforecast.2003.09.015>, Winters (1960) <doi:10.1287/mnsc.6.3.324>, Cleveland, Cleveland, & Terpenning (1990) "STL: A Seasonal-Trend Decomposition Procedure Based on Loess".

This package provides a collection of tools for detecting influential cases in generalized mixed effects models. It analyses models that were estimated using lme4'. The basic rationale behind identifying influential data is that when single units are omitted from the data, models based on these data should not produce substantially different estimates. To standardize the assessment of how influential a (single group of) observation(s) is, several measures of influence are common practice, such as Cook's Distance. In addition, we provide a measure of percentage change of the fixed point estimates and a simple procedure to detect changing levels of significance.

Interpretation methods for analyzing the behavior and individual predictions of modern neural networks in a three-step procedure: Converting the model, running the interpretation method, and visualizing the results. Implemented methods are, e.g., Connection Weights described by Olden et al. (2004) <doi:10.1016/j.ecolmodel.2004.03.013>, layer-wise relevance propagation ('LRP') described by Bach et al. (2015) <doi:10.1371/journal.pone.0130140>, deep learning important features ('DeepLIFT') described by Shrikumar et al. (2017) <doi:10.48550/arXiv.1704.02685> and gradient-based methods like SmoothGrad described by Smilkov et al. (2017) <doi:10.48550/arXiv.1706.03825>, Gradient x Input or Vanilla Gradient'. Details can be found in the accompanying scientific paper: Koenen & Wright (2024, Journal of Statistical Software, <doi:10.18637/jss.v111.i08>).

This package provides examples of code for analyzing data or accomplishing tasks that may be useful to institutional or educational researchers.

This package provides a comprehensive analytics framework for building reproducible pipelines on T-cell and B-cell immune receptor repertoire data. Delivers multi-modal immune profiling (bulk, single-cell, CITE-seq/AbSeq, spatial, immunogenicity data), feature engineering (ML-ready feature tables and matrices), and biomarker discovery workflows (cohort comparisons, longitudinal tracking, repertoire similarity, enrichment). Provides a user-friendly interface to widely used AIRR methods â clonality/diversity, V(D)J usage, similarity, annotation, tracking, and many more. Think Scanpy or Seurat, but for AIRR data, a.k.a. Adaptive Immune Receptor Repertoire, VDJ-seq, RepSeq, or VDJ sequencing data. A successor to our previously published "tcR" R package (Nazarov 2015).

This package provides functions to perform robust nonparametric survival analysis with right censored data using a prior near-ignorant Dirichlet Process. Mangili, F., Benavoli, A., de Campos, C.P., Zaffalon, M. (2015) <doi:10.1002/bimj.201500062>.

This package provides a collection of several functions related to construction and analysis of incomplete split-plot designs. The package contains functions to obtain and analyze incomplete split-plot designs for three kinds of situations namely (i) when blocks are complete with respect to main plot treatments and main plots are incomplete with respect to subplot treatments, (ii) when blocks are incomplete with respect to main plot treatments and main plots are complete with respect to subplot treatments and (iii) when blocks are incomplete with respect to main plot treatments and main plots are incomplete with respect to subplot treatments.

This package implements a Shiny Item Analysis module and functions for computing false positive rate and other binary classification metrics from inter-rater reliability based on Bartoš & Martinková (2024) <doi:10.1111/bmsp.12343>.

Density, spectral density, and regression estimation using infinite order flat-top kernels.

Run quality checks on data sets using the same checks that are conducted on the ICES Data Submission Utility (DATSU) <https://datsu.ices.dk>.

Calculate AIC's and AICc's of unimodal model (one normal distribution) and bimodal model(a mixture of two normal distributions) which fit the distribution of indices of asymmetry (IAS), and plot their density, to help determine IAS distribution is unimodal or bimodal.