This package implements the compartment model from Tokars (2018) <doi:10.1016/j.vaccine.2018.10.026>. This enables quantification of population-wide impact of vaccination against vaccine-preventable diseases such as influenza.

This package provides a multivariate Gaussian mixture model framework to integrate multiple types of genomic data and allow modeling of inter-data-type correlations for association analysis. IMIX can be implemented to test whether a disease is associated with genes in multiple genomic data types, such as DNA methylation, copy number variation, gene expression, etc. It can also study the integration of multiple pathways. IMIX uses the summary statistics of association test outputs and conduct integration analysis for two or three types of genomics data. IMIX features statistically-principled model selection, global FDR control and computational efficiency. Details are described in Ziqiao Wang and Peng Wei (2020) <doi:10.1093/bioinformatics/btaa1001>.

This package provides functions to clean and process international trade data into an international trade network (ITN) are provided. It then provides a set a functions to undertake analysis and plots of the ITN (extract the backbone, centrality, blockmodels, clustering). Examining the key players in the ITN and regional trade patterns.

Simulate and implement early phase two-stage adaptive dose-finding design for binary and quasi-continuous toxicity endpoints. See Chiuzan et al. (2018) for further reading <DOI:10.1080/19466315.2018.1462727>.

This package provides a framework for analysing inbreeding and heterozygosity-fitness correlations (HFCs) based on microsatellite and SNP markers.

ISA is a metadata framework to manage an increasingly diverse set of life science, environmental and biomedical experiments. In isatabr methods for reading, modifying and writing of files in the ISA-Tab format are implemented. It also contains methods for processing assay data.

This package provides methods to perform and analyse I-prior regression models. Estimation is done either via direct optimisation of the log-likelihood or an EM algorithm.

Coefficients of Interrater Reliability and Agreement for quantitative, ordinal and nominal data: ICC, Finn-Coefficient, Robinson's A, Kendall's W, Cohen's Kappa, ...

This package provides a multi-layered untargeted pipeline for high-throughput LC/HRMS data processing to extract signals of organic small molecules. The package performs ion pairing, peak detection, peak table alignment, retention time correction, aligned peak table gap filling, peak annotation and visualization of extracted ion chromatograms (EICs) and total ion chromatograms (TICs). The IDSL.IPA package was introduced in <doi:10.1021/acs.jproteome.2c00120> .

This package implements the Interval Consensus Model (ICM) for analyzing continuous bounded interval-valued responses in psychometrics using Stan for Bayesian estimation. Provides functions for transforming interval data to simplex representations, fitting item response theory (IRT) models with isometric log-ratio (ILR) and sum log-ratio (SLR) link functions, and visualizing results. The package enables aggregation and analysis of interval-valued response data commonly found in psychological measurement and related disciplines. Based on Kloft et al. (2024) <doi:10.31234/osf.io/dzvw2>.

This package provides functions to access data from public RESTful APIs including World Bank API', and REST Countries API', retrieving real-time or historical data related to India, such as economic indicators, and international demographic and geopolitical indicators. Additionally, the package includes one of the largest curated collections of open datasets focused on India, covering topics such as population, economy, weather, politics, health, biodiversity, sports, agriculture, cybercrime, infrastructure, and more. The package supports reproducible research and teaching by integrating reliable international APIs and structured datasets from public, academic, and government sources. For more information on the APIs, see: World Bank API <https://datahelpdesk.worldbank.org/knowledgebase/articles/889392>, REST Countries API <https://restcountries.com/>.

Note that imageData has been superseded by growthPheno'. The package growthPheno incorporates all the functionality of imageData and has functionality not available in imageData', but some imageData functions have been renamed. The imageData package is no longer maintained, but is retained for legacy purposes.

This package provides access to the Idea Data Center (IDC) application for conducting nonresponse bias analysis (NRBA). The IDC NRBA app is an interactive, browser-based Shiny application that can be used to analyze survey data with respect to response rates, representativeness, and nonresponse bias. This app provides a user-friendly interface to statistical methods implemented by the nrba package. Krenzke, Van de Kerckhove, and Mohadjer (2005) <http://www.asasrms.org/Proceedings/y2005/files/JSM2005-000572.pdf> and Lohr and Riddles (2016) <https://www150.statcan.gc.ca/n1/en/pub/12-001-x/2016002/article/14677-eng.pdf?st=q7PyNsGR> provide an overview of the statistical methods implemented in the application.

Builds statistical control charts with exact limits for univariate and multivariate cases.

This package implements a modification to the Random Survival Forests algorithm for obtaining variable importance in high dimensional datasets. The proposed algorithm is appropriate for settings in which a silent event is observed through sequentially administered, error-prone self-reports or laboratory based diagnostic tests. The modified algorithm incorporates a formal likelihood framework that accommodates sequentially administered, error-prone self-reports or laboratory based diagnostic tests. The original Random Survival Forests algorithm is modified by the introduction of a new splitting criterion based on a likelihood ratio test statistic.

Enable user to find the IP addresses which are used as VPN anonymizer, open proxies, web proxies and Tor exits. The package lookup the proxy IP address from IP2Proxy BIN Data file. You may visit <https://lite.ip2location.com> for free database download.

Incremental Multiple Correspondence Analysis and Principal Component Analysis.

Regression models for interval censored data. Currently supports Cox-PH, proportional odds, and accelerated failure time models. Allows for semi and fully parametric models (parametric only for accelerated failure time models) and Bayesian parametric models. Includes functions for easy visual diagnostics of model fits and imputation of censored data.

Utility functions that implement and automate common sets of validation tasks. These functions are particularly useful to validate inputs, intermediate objects and output values in user-defined functions, resulting in tidier and less verbose functions.

An implementation of the Invariance Partial Pruning (IVPP) approach described in Du, X., Johnson, S. U., Epskamp, S. (2025) The Invariance Partial Pruning Approach to The Network Comparison in Longitudinal Data. IVPP is a two-step method that first test for global network structural difference with invariance test and then inspect specific edge difference with partial pruning.

Integrated toolbox supporting common file formats used for intracranial Electroencephalography (iEEG) and deep-brain stimulation (DBS) study.

Boxplots adapted to the happenstance of missing observations where drop-out probabilities can be given by the practitioner or modelled using auxiliary covariates. The paper of "Zhang, Z., Chen, Z., Troendle, J. F. and Zhang, J.(2012) <doi:10.1111/j.1541-0420.2011.01712.x>", proposes estimators of marginal quantiles based on the Inverse Probability Weighting method.

Check if an externalptr is a null pointer. R does currently not have a native function for that purpose. This package contains a C function that returns TRUE in case of a null pointer.

Estimates weights to make a continuous-valued exposure statistically independent of a vector of pre-treatment covariates using the method proposed in Huling, Greifer, and Chen (2021) <arxiv:2107.07086>.