The harmonic mean p-value (HMP) test combines p-values and corrects for multiple testing while controlling the strong-sense family-wise error rate. It is more powerful than common alternatives including Bonferroni and Simes procedures when combining large proportions of all the p-values, at the cost of slightly lower power when combining small proportions of all the p-values. It is more stringent than controlling the false discovery rate, and possesses theoretical robustness to positive correlations between tests and unequal weights. It is a multi-level test in the sense that a superset of one or more significant tests is certain to be significant and conversely when the superset is non-significant, the constituent tests are certain to be non-significant. It is based on MAMML (model averaging by mean maximum likelihood), a frequentist analogue to Bayesian model averaging, and is theoretically grounded in generalized central limit theorem. For detailed examples type vignette("harmonicmeanp") after installation. Version 3.0 addresses errors in versions 1.0 and 2.0 that led function p.hmp to control the familywise error rate only in the weak sense, rather than the strong sense as intended.

The package allows to simulate Hawkes process both in univariate and multivariate settings. It gives functions to compute different moments of the number of jumps of the process on a given interval, such as mean, variance or autocorrelation of process jumps on time intervals separated by a lag.

Inference of chromosome-length haplotypes using a few haploid gametes of an individual. The gamete genotype data may be generated from various platforms including genotyping arrays and sequencing even with low-coverage. Hapi simply takes genotype data of known hetSNPs in single gamete cells as input and report the high-resolution haplotypes as well as confidence of each phased hetSNPs. The package also includes a module allowing downstream analyses and visualization of identified crossovers in the gametes.

Kernel density estimation with hexagonal grid for bivariate data. Hexagonal grid has many beneficial properties like equidistant neighbours and less edge bias, making it better for spatial analyses than the more commonly used rectangular grid. Carr, D. B. et al. (1987) <doi:10.2307/2289444>. Diggle, P. J. (2010) <doi:10.1201/9781420072884>. Hill, B. (2017) <https://blog.bruce-hill.com/meandering-triangles>. Jones, M. C. (1993) <doi:10.1007/BF00147776>.

Hospital time series data analysis workflow tools, modeling, and automations. This library provides many useful tools to review common administrative time series hospital data. Some of these include average length of stay, and readmission rates. The aim is to provide a simple and consistent verb framework that takes the guesswork out of everything.

Generates synthetic electronic health record data, including patients, encounters, vitals, laboratory results, medications, procedures, and allergies. The package supports optional SARS-focused and computed tomography (CT) research views and export to CSV, SQLite, and Excel formats for research and development workflows.

Datasets related to Hong Kong, including information on the 2019 elected District Councillors (<https://www.districtcouncils.gov.hk> and <https://dce2019.hk01.com/>) and traffic collision data from the Hong Kong Department of Transport (<https://www.td.gov.hk/>). All of the data in this package is available in the public domain.

Estimates the shape and volume of high-dimensional datasets and performs set operations: intersection / overlap, union, unique components, inclusion test, and hole detection. Uses stochastic geometry approach to high-dimensional kernel density estimation, support vector machine delineation, and convex hull generation. Applications include modeling trait and niche hypervolumes and species distribution modeling.

This package implements an efficient algorithm for fitting the entire regularization path of support vector machine models with elastic-net penalties using a generalized coordinate descent scheme. The framework also supports SCAD and MCP penalties. It is designed for high-dimensional datasets and emphasizes numerical accuracy and computational efficiency. This package implements the algorithms proposed in Tang, Q., Zhang, Y., & Wang, B. (2022) <https://openreview.net/pdf?id=RvwMTDYTOb>.

Fast, documented implementations of robust estimation, testing, dimension reduction, classification, and clustering methods for high-dimensional elliptically symmetric data. Computational kernels use Rcpp and RcppArmadillo'. The package follows methods reviewed in Feng (2026), "High-Dimensional Data Analysis for Elliptically Symmetric Distributions" <https://github.com/flnankai/HDElliptical/releases>.

This package provides an interface to HDFql <https://www.hdfql.com/> and helper functions for reading data from and writing data to HDF5 files. HDFql provides a high-level language for managing HDF5 data that is platform independent. For more information, see the reference manual <https://www.hdfql.com/resources/HDFqlReferenceManual.pdf>.

Automatic construction of regular and irregular histograms as described in Rozenholc/Mildenberger/Gather (2010).

This package performs a homogeneity analysis (multiple correspondence analysis) and various extensions. Rank restrictions on the category quantifications can be imposed (nonlinear PCA). The categories are transformed by means of optimal scaling with options for nominal, ordinal, and numerical scale levels (for rank-1 restrictions). Variables can be grouped into sets, in order to emulate regression analysis and canonical correlation analysis.

S3 functions implementing both statistical and graphical goodness-of-fit measures between observed and simulated values, mainly oriented to be used during the calibration, validation, and application of hydrological models. Missing values in observed and/or simulated values can be removed before computations. Comments / questions / collaboration of any kind are very welcomed.

It performs maximum likelihood estimation for the Heckman selection model (Normal, Student-t or Contaminated normal) using an EM-algorithm <doi:10.1016/j.jmva.2021.104737>. It also performs influence diagnostic through global and local influence for four possible perturbation schema.

We provide the monthly number of HIV and antiretroviral therapy (ART) cases of male, female, children and transgender as well as for the whole of Pakistan reported at various treatment centers in Pakistan from January 2016 to December 2021. Related works include: a) Imran, M., Nasir, J. A., & Riaz, S. (2018). Regional pattern of HIV cases in Pakistan. Journal of Postgraduate Medical Institute, 32(1), 9-13. <https://jpmi.org.pk/index.php/jpmi/article/view/2108>.

Create publication-quality, 2-dimensional visualizations of alpha-helical peptide sequences. Specifically, allows the user to programmatically generate helical wheels and wenxiang diagrams to provide a bird's eye, top-down view of alpha-helical oligopeptides. See Wadhwa RR, et al. (2018) <doi:10.21105/joss.01008> for more information.

This package provides a dependency free interface to the H3 geospatial indexing system utilizing the Rust library h3o <https://github.com/HydroniumLabs/h3o> via the extendr library <https://github.com/extendr/extendr>.

This package implements the sample size methods for hierarchical 2x2 factorial trials under two choices of effect estimands and a series of hypothesis tests proposed in "Sample size calculation in hierarchical 2x2 factorial trials with unequal cluster sizes" (under review), and provides the table and plot generators for the sample size estimations.

This package provides data for functions typically used in the healthyR package.

Homomorphic encryption (Brakerski and Vaikuntanathan (2014) <doi:10.1137/120868669>) using Ring Learning with Errors (Lyubashevsky et al. (2012) <https://eprint.iacr.org/2012/230>) is a form of Learning with Errors (Regev (2005) <doi:10.1145/1060590.1060603>) using polynomial rings over finite fields. Functions to generate the required polynomials (using polynom'), with various distributions of coefficients are provided. Additionally, functions to generate and take coefficient modulo are provided.

The HistData package provides a collection of small data sets that are interesting and important in the history of statistics and data visualization. The goal of the package is to make these available, both for instructional use and for historical research. Some of these present interesting challenges for graphics or analysis in R.

The Hierarchical Neyman-Pearson (H-NP) classification framework extends the Neyman-Pearson classification paradigm to multi-class settings where classes have a natural priority ordering. This is particularly useful for classification in unbalanced dataset, for example, disease severity classification, where under-classification errors (misclassifying patients into less severe categories) are more consequential than other misclassifications. The package implements H-NP umbrella algorithms that controls under-classification errors under user specified control levels with high probability. It supports the creation of H-NP classifiers using scoring functions based on built-in classification methods (including logistic regression, support vector machines, and random forests), as well as user-trained scoring functions. The package exports `base_function()` to train these built-in base learners directly for use in the H-NP pipeline.

Estimating heterogeneous treatment effects with tree-based machine learning algorithms and visualizing estimated results in flexible and presentation-ready ways. For more information, see Brand, Xu, Koch, and Geraldo (2021) <doi:10.1177/0081175021993503>. Our current package first started as a fork of the causalTree package on GitHub and we greatly appreciate the authors for their extremely useful and free package.