This package provides methods to perform Joint graph Regularized Single-Cell Kullback-Leibler Sparse Non-negative Matrix Factorization ('jrSiCKLSNMF', pronounced "junior sickles NMF") on quality controlled single-cell multimodal omics count data. jrSiCKLSNMF specifically deals with dual-assay scRNA-seq and scATAC-seq data. This package contains functions to extract meaningful latent factors that are shared across omics modalities. These factors enable accurate cell-type clustering and facilitate visualizations. Methods for pre-processing, clustering, and mini-batch updates and other adaptations for larger datasets are also included. For further details on the methods used in this package please see Ellis, Roy, and Datta (2023) <doi:10.3389/fgene.2023.1179439>.

Computes the Jackknife Mutual Information (JMI) between two random vectors and provides the p-value for dependence tests. See Zeng, X., Xia, Y. and Tong, H. (2018) <doi:10.1073/pnas.1715593115>.

Minimal and memory efficient implementation of the junction tree algorithm using the Lauritzen-Spiegelhalter scheme; S. L. Lauritzen and D. J. Spiegelhalter (1988) <https://www.jstor.org/stable/2345762?seq=1>. The jti package is part of the paper <doi:10.18637/jss.v111.i02>.

This package implements an S4 distribution system and estimation methods for parameters of common distribution families. The common d, p, q, r function family for each distribution is enriched with the ll, e, and v counterparts, computing the log-likelihood, performing estimation, and calculating the asymptotic variance - covariance matrix, respectively. Parameter estimation is performed analytically whenever possible.

Takes an R expression and returns a job object with a $stop() method which can be called to terminate the background job. Also provides timeouts and other mechanisms for automatically terminating a background job. The result of the expression is available synchronously via $result or asynchronously with callbacks or through the promises package framework.

Fast extrapolation of univariate and multivariate time features using K-Nearest Neighbors. Version 2.0 adds approximate nearest-neighbor search, optional GPU acceleration, probabilistic forecast distributions, conformal prediction intervals, and multi-scale sequence representations. The compact set of hyper-parameters is tuned via grid or random search.

This package performs Joins and Minus Queries on Excel Files fulljoinXL() Merges all rows of 2 Excel files based upon a common column in the files. innerjoinXL() Merges all rows from base file and join file when the join condition is met. leftjoinXL() Merges all rows from the base file, and all rows from the join file if the join condition is met. rightjoinXL() Merges all rows from the join file, and all rows from the base file if the join condition is met. minusXL() Performs 2 operations source-minus-target and target-minus-source If the files are identical all output files will be empty. Choose two Excel files via a dialog box, and then follow prompts at the console to choose a base or source file and columns to merge or minus on.

Joint mean and dispersion effects models fit the mean and dispersion parameters of a response variable by two separate linear models, the mean and dispersion submodels, simultaneously. It also allows the users to choose either the deviance or the Pearson residuals as the response variable of the dispersion submodel. Furthermore, the package provides the possibility to nest the submodels in one another, if one of the parameters has significant explanatory power on the other. Wu & Li (2016) <doi:10.1016/j.csda.2016.04.015>.

Allows to import functions and whole packages from Julia in R. Imported Julia functions can directly be called as R functions. Data structures can be translated between Julia and R. More details can also be found in the corresponding article <doi:10.18637/jss.v101.i06>.

This package provides analysis tools for big data where the sample size is very large. It offers a suite of functions for fitting and predicting joint models, which allow for the simultaneous analysis of longitudinal and time-to-event data. This statistical methodology is particularly useful in medical research where there is often interest in understanding the relationship between a longitudinal biomarker and a clinical outcome, such as survival or disease progression. This can be particularly useful in a clinical setting where it is important to be able to predict how a patient's health status may change over time. Overall, this package provides a comprehensive set of tools for joint modeling of BIG data obtained as survival and longitudinal outcomes with both Bayesian and non-Bayesian approaches. Its versatility and flexibility make it a valuable resource for researchers in many different fields, particularly in the medical and health sciences.

This package implements the basic financial analysis functions similar to (but not identical to) what is available in most spreadsheet software. This includes finding the IRR and NPV of regularly spaced cash flows and annuities. Bond pricing and YTM calculations are included. In addition, Black Scholes option pricing and Greeks are also provided.

Analysis of repeated measurements and time-to-event data via random effects joint models. Fits the joint models proposed by Henderson and colleagues <doi:10.1093/biostatistics/1.4.465> (single event time) and by Williamson and colleagues (2008) <doi:10.1002/sim.3451> (competing risks events time) to a single continuous repeated measure. The time-to-event data is modelled using a (cause-specific) Cox proportional hazards regression model with time-varying covariates. The longitudinal outcome is modelled using a linear mixed effects model. The association is captured by a latent Gaussian process. The model is estimated using an Expectation Maximization algorithm. Some plotting functions and the variogram are also included. This project is funded by the Medical Research Council (Grant numbers G0400615 and MR/M013227/1).

Metaprogramming utilities for converting R regression model formulae to equivalents in Julia <doi:10.1137/141000671>, via modifications to the abstract syntax tree. Supports translations in zero correlation random effects syntax, protection of expressions to be evaluated as-is, interaction terms, and more. Accepts strings or R formula objects and returns modified R formula objects where possible (or a modified string, if not a valid formula in R).

This package provides tools for drawing maps of Japan with prefecture and municipal boundaries. The plotting workflow mirrors the usmap package and includes a transform that moves Okinawa and Ogasawara into visible inset locations. Boundary helpers build local GeoPackage files from Japan's official MLIT N03 administrative area data <https://nlftp.mlit.go.jp/ksj/gml/datalist/KsjTmplt-N03-2024.html>.

This package provides a set of wrappers around rjags functions to run Bayesian analyses in JAGS (specifically, via libjags'). A single function call can control adaptive, burn-in, and sampling MCMC phases, with MCMC chains run in sequence or in parallel. Posterior distributions are automatically summarized (with the ability to exclude some monitored nodes if desired) and functions are available to generate figures based on the posteriors (e.g., predictive check plots, traceplots). Function inputs, argument syntax, and output format are nearly identical to the R2WinBUGS'/'R2OpenBUGS packages to allow easy switching between MCMC samplers.

Joint analysis and imputation of incomplete data in the Bayesian framework, using (generalized) linear (mixed) models and extensions there of, survival models, or joint models for longitudinal and survival data, as described in Erler, Rizopoulos and Lesaffre (2021) <doi:10.18637/jss.v100.i20>. Incomplete covariates, if present, are automatically imputed. The package performs some preprocessing of the data and creates a JAGS model, which will then automatically be passed to JAGS <https://mcmc-jags.sourceforge.io/> with the help of the package rjags'.

This package provides model fitting, prediction, and plotting for joint models of longitudinal and multiple time-to-event data, including methods from Rizopoulos (2012) <doi:10.1201/b12208>. Useful for handling complex survival and longitudinal data in clinical research.

Uses the Jaccard similarity index to account for population structure in sequencing studies. This method was specifically designed to detect population stratification based on rare variants, hence it will be especially useful in rare variant analysis.

Bayesian methods for estimating developmental age from ordinal dental data. For an explanation of the model used, see Konigsberg (2015) <doi:10.3109/03014460.2015.1045430>. For details on the conditional correlation correction, see Sgheiza (2022) <doi:10.1016/j.forsciint.2021.111135>. Dental scoring is based on Moorrees, Fanning, and Hunt (1963) <doi:10.1177/00220345630420062701>.

An R package that implements the JICO algorithm [Wang, P., Wang, H., Li, Q., Shen, D., & Liu, Y. (2024). <Journal of Computational and Graphical Statistics, 33(3), 763-773>]. It aims at solving the multi-group regression problem. The algorithm decomposes the responses from multiple groups into shared and group-specific components, which are driven by low-rank approximations of joint and individual structures from the covariates respectively.

Bayesian data analysis usually incurs long runtimes and cumbersome custom code. A pipeline toolkit tailored to Bayesian statisticians, the jagstargets R package is leverages targets and R2jags to ease this burden. jagstargets makes it super easy to set up scalable JAGS pipelines that automatically parallelize the computation and skip expensive steps when the results are already up to date. Minimal custom code is required, and there is no need to manually configure branching, so usage is much easier than targets alone. For the underlying methodology, please refer to the documentation of targets <doi:10.21105/joss.02959> and JAGS (Plummer 2003) <https://www.r-project.org/conferences/DSC-2003/Proceedings/Plummer.pdf>.

This package provides a set of helper functions to conduct joint-significance tests for mediation analysis, as recommended by Yzerbyt, Muller, Batailler, & Judd. (2018) <doi:10.1037/pspa0000132>.

This package implements the Merton (1976) <doi:10.1016/0304-405X(76)90022-2> and Kou (2002) <doi:10.1287/mnsc.48.8.1086.166> jump-diffusion models through a unified S4 object-oriented interface. Provides exact compound-Poisson asset price simulation, maximum likelihood parameter estimation with Hessian-based standard errors, Wald-type confidence intervals, European option pricing via the Merton analytic series expansion, and publication-quality diagnostic plots. All functionality operates entirely offline without market data dependencies.

These functions calculate the taxonomic measures presented in Miranda-Esquivel (2016). The package introduces Jack-knife resampling in evolutionary distinctiveness prioritization analysis, as a way to evaluate the support of the ranking in area prioritization, and the persistence of a given area in a conservation analysis. The algorithm is described in: Miranda-Esquivel, D (2016) <DOI:10.1007/978-3-319-22461-9_11>.