This package provides fast implementations of kernel smoothing techniques for bivariate copula densities, in particular density estimation and resampling, see Nagler (2018) <doi:10.18637/jss.v084.i07>.

This package provides a multi-purpose and flexible k-meric enrichment analysis software. kmeRtone measures the enrichment of k-mers by comparing the population of k-mers in the case loci with a carefully devised internal negative control group, consisting of k-mers from regions close to, yet sufficiently distant from, the case loci to mitigate any potential sequencing bias. This method effectively captures both the local sequencing variations and broader sequence influences, while also correcting for potential biases, thereby ensuring more accurate analysis. The core functionality of kmeRtone is the SCORE() function, which calculates the susceptibility scores for k-mers in case and control regions. Case regions are defined by the genomic coordinates provided in a file by the user and the control regions can be constructed relative to the case regions or provided directly. The k-meric susceptibility scores are calculated by using a one-proportion z-statistic. kmeRtone is highly flexible by allowing users to also specify their target k-mer patterns and quantify the corresponding k-mer enrichment scores in the context of these patterns, allowing for a more comprehensive approach to understanding the functional implications of specific DNA sequences on a genomic scale (e.g., CT motifs upon UV radiation damage). Adib A. Abdullah, Patrick Pflughaupt, Claudia Feng, Aleksandr B. Sahakyan (2024) Bioinformatics (submitted).

Training and evaluating k-gram language models in R, supporting several probability smoothing techniques, perplexity computations, random text generation and more.

Data on houses in and around Seattle WA are included. Basic characteristics are given along with sale prices.

k Nearest Neighbors with variable selection, combine grid search and forward selection to achieve variable selection in order to improve k Nearest Neighbors predictive performance.

The King's Health Questionnaire (KHQ) is a disease-specific, self-administered questionnaire designed specific to assess the impact of Urinary Incontinence (UI) on Quality of Life. The questionnaire was developed by Kelleher and collaborators (1997) <doi:10.1111/j.1471-0528.1997.tb11006.x>. It is a simple, acceptable and reliable measure to use in the clinical setting and a research tool that is useful in evaluating UI treatment outcomes. The KHQ five dimensions (KHQ5D) is a condition-specific preference-based measure developed by Brazier and collaborators (2008) <doi:10.1177/0272989X07301820>. Although not as popular as the SF6D <doi:10.1016/S0895-4356(98)00103-6> and EQ-5D <https://euroqol.org/>, the KHQ5D measures health-related quality of life (HRQoL) specifically for UI, not general conditions like the others two instruments mentioned. The KHQ5D ca be used in the clinical and economic evaluation of health care. The subject self-rates their health in terms of five dimensions: Role Limitation (RL), Physical Limitations (PL), Social Limitations (SL), Emotions (E), and Sleep (S). Frequently the states on these five dimensions are converted to a single utility index using country specific value sets, which can be used in the clinical and economic evaluation of health care as well as in population health surveys. This package provides methods to calculate scores for each dimension of the KHQ; converts KHQ item scores to KHQ5D scores; and also calculates the utility index of the KHQ5D.

Identification of putative causal variants in genome-wide association studies using hybrid analysis of both the trio and population designs. The package implements the method in the paper: Yang, Y., Wang, Q., Wang, C., Buxbaum, J., & Ionita-Laza, I. (2024). KnockoffHybrid: A knockoff framework for hybrid analysis of trio and population designs in genome-wide association studies. The American Journal of Human Genetics, in press.

Comparative evaluation of families and candidate variants in rare-variant association studies. The package can be used for two methodologically overlapping but distinct purposes. First, the prior to any genetic or genomic evaluation, evaluation of relative detection power of pedigrees, can direct recruitment efforts by showing which individuals not yet sampled would be the most meaningful additions to a study. Second, after sequencing and analysis, variants based on association with disease status and familial relationships of individuals, aids in variant prioritization. Methodology is described in Nugent (2025) <doi:10.1101/2025.10.06.25337426>.

API wrapper to download statistical information from the Korean Statistical Information Service (KOSIS) <https://kosis.kr/openapi/index/index.jsp>.

Access business registration data from the Dutch Chamber of Commerce (Kamer van Koophandel, KvK) through their official API <https://developers.kvk.nl/>. Search for companies by name, location, or registration number. Retrieve detailed business profiles, establishment information, and company name histories. Built on httr2 for robust API interaction with automatic pagination, error handling, and usage tracking.

It predicts any attribute (categorical) given a set of input numeric predictor values. Note that only numeric input predictors should be given. The k value can be chosen according to accuracies provided. The attribute to be predicted can be selected from the dropdown provided (select categorical attribute). This is because categorical attributes cannot be given as inputs here. A handsontable is also provided to enter the input predictor values.

Local explanations of machine learning models describe, how features contributed to a single prediction. This package implements an explanation method based on LIME (Local Interpretable Model-agnostic Explanations, see Tulio Ribeiro, Singh, Guestrin (2016) <doi:10.1145/2939672.2939778>) in which interpretable inputs are created based on local rather than global behaviour of each original feature.

An implementation of a method of extending a logistic regression model beyond linear effects of the co-variates. The extension in is constructed by first equating the logistic regression model to a naive Bayes model where all the margins are specified to follow natural exponential distributions conditional on Y, that is, a model for Y given X that is specified through the distribution of X given Y, where the columns of X are assumed to be mutually independent conditional on Y. Subsequently, the model is expanded by adding vine - copulas to relax the assumption of mutual independence, where pair-copulas are added in a stage-wise, forward selection manner. Some heuristics are employed during the process of selecting edges, as well as the families of pair-copula models. After each component is added, the parameters are updated by a (smaller) number of gradient steps to maximise the likelihood. When the algorithm has stopped adding edges, based the criterion that a new edge should improve the likelihood more than k times the number new parameters, the parameters are updated with a larger number of gradient steps, or until convergence.

It allows to cluster communication networks using the Stochastic Topic Block Model <doi:10.1007/s11222-016-9713-7> by posting jobs through the API of the linkage.fr server, which implements the clustering method. The package also allows to visualize the clustering results returned by the server.

Sparklines are small plots (about one line of text high), made popular by Edward Tufte. This package is the interface from R to the LaTeX package sparklines by Andreas Loeffer and Dan Luecking (<http://www.ctan.org/pkg/sparklines>). It can work with Sweave or knitr or other engines that produce TeX. The package can be used to plot vectors, matrices, data frames, time series (in ts or zoo format).

This package provides tools for performing Bayesian inference on epidemiological data to estimate the time-varying reproductive number and other related metrics. These methods were published in Li and White (2021) <doi:10.1371/journal.pcbi.1009210>. This package supports analyses based on aggregated case count data and individual line list data, facilitating enhanced surveillance and intervention planning for infectious diseases like COVID-19.

Estimate the sufficient dimension reduction space using sparsed sliced inverse regression via Lasso (Lasso-SIR) introduced in Lin, Zhao, and Liu (2019) <doi:10.1080/01621459.2018.1520115>. The Lasso-SIR is consistent and achieve the optimal convergence rate under certain sparsity conditions for the multiple index models.

Offers a variety of color palettes inspired by art, nature, and personal inspirations. Each palette is accompanied by a unique backstory, enriching the understanding and significance of the colors.

This package provides a high level interface for torch providing utilities to reduce the the amount of code needed for common tasks, abstract away torch details and make the same code work on both the CPU and GPU'. It's flexible enough to support expressing a large range of models. It's heavily inspired by fastai by Howard et al. (2020) <doi:10.48550/arXiv.2002.04688>, Keras by Chollet et al. (2015) and PyTorch Lightning by Falcon et al. (2019) <doi:10.5281/zenodo.3828935>.

This package provides functions for different purposes related to forest biometrics, including illustrative graphics, numerical computation, modeling height-diameter relationships, prediction of tree volumes, modelling of diameter distributions and estimation off stand density using ITD. Several empirical datasets are also included.

An interface to LuaJIT <https://luajit.org>, a just-in-time compiler for the Lua scripting language <https://www.lua.org>. Allows users to run Lua code from R'.

Supervised learning techniques designed for the situation when the dimensionality exceeds the sample size have a tendency to overfit as the dimensionality of the data increases. To remedy this High dimensionality; low sample size (HDLSS) situation, we attempt to learn a lower-dimensional representation of the data before learning a classifier. That is, we project the data to a situation where the dimensionality is more manageable, and then are able to better apply standard classification or clustering techniques since we will have fewer dimensions to overfit. A number of previous works have focused on how to strategically reduce dimensionality in the unsupervised case, yet in the supervised HDLSS regime, few works have attempted to devise dimensionality reduction techniques that leverage the labels associated with the data. In this package and the associated manuscript Vogelstein et al. (2017) <arXiv:1709.01233>, we provide several methods for feature extraction, some utilizing labels and some not, along with easily extensible utilities to simplify cross-validative efforts to identify the best feature extraction method. Additionally, we include a series of adaptable benchmark simulations to serve as a standard for future investigative efforts into supervised HDLSS. Finally, we produce a comprehensive comparison of the included algorithms across a range of benchmark simulations and real data applications.

This package provides fast and scalable Gibbs sampling algorithms for Bayesian Lasso regression model in high-dimensional settings. The package implements efficient partially collapsed and nested Gibbs samplers for Bayesian Lasso, with a focus on computational efficiency when the number of predictors is large relative to the sample size. Methods are described at Davoudabadi and Ormerod (2026) <https://github.com/MJDavoudabadi/LassoHiDFastGibbs>.

This package provides functions to access and test results from a linear model.