Correct identification and handling of missing data is one of the most important steps in any analysis. To aid this process, mde provides a very easy to use yet robust framework to quickly get an idea of where the missing data lies and therefore find the most appropriate action to take. Graham WJ (2009) <doi:10.1146/annurev.psych.58.110405.085530>.

This package provides a comprehensive tool for almost all existing multiple testing methods for discrete data. The package also provides some novel multiple testing procedures controlling FWER/FDR for discrete data. Given discrete p-values and their domains, the [method].p.adjust function returns adjusted p-values, which can be used to compare with the nominal significant level alpha and make decisions. For users convenience, the functions also provide the output option for printing decision rules.

This package provides tools for cleaning, processing, and preparing microbiome sequencing data (e.g., 16S rRNA) for downstream analysis. Supports CSV, TXT, and Excel file formats. The main function, ezclean(), automates microbiome data transformation, including format validation, transposition, numeric conversion, and metadata integration. It also handles taxonomic levels efficiently, resolves duplicated taxa entries, and outputs a well-structured, analysis-ready dataset. The companion functions ezstat() run statistical tests and summarize results, while ezviz() produces publication-ready visualizations.

Makes a word cloud of text, sized by the frequency of the word, and colored either by user-specified colors or colored by the strength of the coefficient of that text derived from a regression model.

Enables you to create accessible modal dialogs, with confidence and with minimal configuration.

Fits the MESSI, hard constraint, and unconstrained models in Boss et al. (2023) <doi:10.48550/arXiv.2306.17347> for mediation analyses with external summary-level information on the total effect.

Create and integrate thematic maps in your workflow. This package helps to design various cartographic representations such as proportional symbols, choropleth or typology maps. It also offers several functions to display layout elements that improve the graphic presentation of maps (e.g. scale bar, north arrow, title, labels). mapsf maps sf objects on base graphics.

An implementation of classifier chains (CC's) for multi-label prediction. Users can employ an external package (e.g. randomForest', C50'), or supply their own. The package can train a single set of CC's or train an ensemble of CC's -- in parallel if running in a multi-core environment. New observations are classified using a Gibbs sampler since each unobserved label is conditioned on the others. The package includes methods for evaluating the predictions for accuracy and aggregating across iterations and models to produce binary or probabilistic classifications.

Plot the daily and cumulative number of downloads of your packages. It is designed to be slightly more convenient than the several similar programs. If you want to run this each morning, you do not need to keep typing in the names of your packages. Also, this combines the daily and cumulative counts in one run, you do not need to run separate programs to get both types of information.

Package for estimating, analyzing, and forecasting multi-country macro-finance affine term structure models (ATSMs). All setups build on the single-country unspanned macroeconomic risk framework from Joslin, Priebsch, and Singleton (2014, JF) <doi:10.1111/jofi.12131>. Multicountry extensions by Jotikasthira, Le, and Lundblad (2015, JFE) <doi:10.1016/j.jfineco.2014.09.004>, Candelon and Moura (2023, EM) <doi:10.1016/j.econmod.2023.106453>, and Candelon and Moura (2024, JFEC) <doi:10.1093/jjfinec/nbae008> are also available. The package also provides tools for bias correction as in Bauer Rudebusch and Wu (2012, JBES) <doi:10.1080/07350015.2012.693855>, bootstrap analysis, and several graphical/numerical outputs.

Estimates Variable Length Markov Chains (VLMC) models and VLMC with covariates models from discrete sequences. Supports model selection via information criteria and simulation of new sequences from an estimated model. See Bühlmann, P. and Wyner, A. J. (1999) <doi:10.1214/aos/1018031204> for VLMC and Zanin Zambom, A., Kim, S. and Lopes Garcia, N. (2022) <doi:10.1111/jtsa.12615> for VLMC with covariates.

This package provides a variety of association tests for microbiome data analysis including Quasi-Conditional Association Tests (QCAT) described in Tang Z.-Z. et al.(2017) <doi:10.1093/bioinformatics/btw804> and Zero-Inflated Generalized Dirichlet Multinomial (ZIGDM) tests described in Tang Z.-Z. & Chen G. (2017, submitted).

Utility functions for working with environmental time series data from known locations. The compact data model is structured as a list with two dataframes. A meta dataframe contains spatial and measuring device metadata associated with deployments at known locations. A data dataframe contains a datetime column followed by columns of measurements associated with each "device-deployment". Ephemerides calculations are based on code originally found in NOAA's "Solar Calculator" <https://gml.noaa.gov/grad/solcalc/>.

This package implements the MST-kNN clustering algorithm which was proposed by Inostroza-Ponta, M. (2008) <https://trove.nla.gov.au/work/28729389?selectedversion=NBD44634158>.

The Cauchy distribution is a special case of the t distribution when the degrees of freedom are equal to 1. The functions are related to the multivariate Cauchy distribution and include simulation, computation of the density, maximum likelihood estimation, contour plot of the bivariate Cauchy distribution, and discriminant analysis. References include: Nadarajah S. and Kotz S. (2008). "Estimation methods for the multivariate t distribution". Acta Applicandae Mathematicae, 102(1): 99--118. <doi:10.1007/s10440-008-9212-8>, and Kanti V. Mardia, John T. Kent and John M. Bibby (1979). "Multivariate analysis", ISBN:978-0124712522. Academic Press, London.

Curve Fitting of monotonic(sigmoidal) & non-monotonic(J-shaped) dose-response data. Predicting mixture toxicity based on reference models such as concentration addition', independent action', and generalized concentration addition'.

Analyses species distribution models and evaluates their performance. It includes functions for variation partitioning, extracting variable importance, computing several metrics of model discrimination and calibration performance, optimizing prediction thresholds based on a number of criteria, performing multivariate environmental similarity surface (MESS) analysis, and displaying various analytical plots. Initially described in Barbosa et al. (2013) <doi:10.1111/ddi.12100>.

Leverages the R language to automate latent variable model estimation and interpretation using Mplus', a powerful latent variable modeling program developed by Muthen and Muthen (<https://www.statmodel.com>). Specifically, this package provides routines for creating related groups of models, running batches of models, and extracting and tabulating model parameters and fit statistics.

Matrix eQTL is designed for fast eQTL analysis on large datasets. Matrix eQTL can test for association between genotype and gene expression using linear regression with either additive or ANOVA genotype effects. The models can include covariates to account for factors as population stratification, gender, and clinical variables. It also supports models with heteroscedastic and/or correlated errors, false discovery rate estimation and separate treatment of local (cis) and distant (trans) eQTLs. For more details see Shabalin (2012) <doi:10.1093/bioinformatics/bts163>.

This package creates and runs Bayesian mixing models to analyze biological tracer data (i.e. stable isotopes, fatty acids), which estimate the proportions of source (prey) contributions to a mixture (consumer). MixSIAR is not one model, but a framework that allows a user to create a mixing model based on their data structure and research questions, via options for fixed/ random effects, source data types, priors, and error terms. MixSIAR incorporates several years of advances since MixSIR and SIAR'.

Generates efficient balanced mixed-level k-circulant supersaturated designs by interchanging the elements of the generator vector. Attempts to generate a supersaturated design that has EfNOD efficiency more than user specified efficiency level (mef). Displays the progress of generation of an efficient mixed-level k-circulant design through a progress bar. The progress of 100 per cent means that one full round of interchange is completed. More than one full round (typically 4-5 rounds) of interchange may be required for larger designs. For more details, please see Mandal, B.N., Gupta V. K. and Parsad, R. (2011). Construction of Efficient Mixed-Level k-Circulant Supersaturated Designs, Journal of Statistical Theory and Practice, 5:4, 627-648, <doi:10.1080/15598608.2011.10483735>.

The MetAlyzer S4 object provides methods to read and reformat metabolomics data for convenient data handling, statistics and downstream analysis. The resulting format corresponds to input data of the Shiny app MetaboExtract (<https://www.metaboextract.shiny.dkfz.de/MetaboExtract/>).

Simulating data and fitting multi-species N-mixture models using nimble'. Includes features for handling zero-inflation and temporal correlation, Bayesian inference, model diagnostics, parameter estimation, and predictive checks. Designed for ecological studies with zero-altered or time-series data. Mimnagh, N., Parnell, A., Prado, E., & Moral, R. A. (2022) <doi:10.1007/s10651-022-00542-7>. Royle, J. A. (2004) <doi:10.1111/j.0006-341X.2004.00142.x>.

The purpose of this package is to share a collection of functions the author wrote during weekends for managing kitchen and garden tasks, e.g. making plant growth charts or Thanksgiving kitchen schedule charts, etc. Functions might include but not limited to: (1) aiding summarizing time related data; (2) generating axis transformation from data; and (3) aiding Markdown (with html output) and Shiny file editing.