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This package creates and runs Bayesian mixing models to analyze biological tracer data (i.e. stable isotopes, fatty acids), which estimate the proportions of source (prey) contributions to a mixture (consumer). MixSIAR is not one model, but a framework that allows a user to create a mixing model based on their data structure and research questions, via options for fixed/ random effects, source data types, priors, and error terms. MixSIAR incorporates several years of advances since MixSIR and SIAR'.
Regularly spaced grids containing continuous data are transformed to contour polygons. A grid can be defined by a data.frame (x, y, value), an sf object or a raster from terra'.
Implementation of Multidimensional Top Scoring method for creativity assessment proposed in Boris Forthmann, Maciej Karwowski, Roger E. Beaty (2023) <doi:10.1037/aca0000571>.
Semi-parametric approach for sparse canonical correlation analysis which can handle mixed data types: continuous, binary and truncated continuous. Bridge functions are provided to connect Kendall's tau to latent correlation under the Gaussian copula model. The methods are described in Yoon, Carroll and Gaynanova (2020) <doi:10.1093/biomet/asaa007> and Yoon, Mueller and Gaynanova (2021) <doi:10.1080/10618600.2021.1882468>.
Query, extract, and plot genealogical data from The Mathematics Genealogy Project <https://mathgenealogy.org/>. Data is gathered from the WebSocket server run by the geneagrapher-core project <https://github.com/davidalber/geneagrapher-core>.
Perform sensitivity analysis on ordinary differential equation based models, including ad-hoc graphical analyses based on structured sequences of parameters as well as local sensitivity analysis. Functions are provided for creating inputs, simulating scenarios and plotting outputs.
This package implements order selection for Vector Autoregressive (VAR) models using the Mean Square Information Criterion (MIC). Unlike standard methods such as AIC and BIC, MIC is likelihood-free. This method consistently estimates VAR order and has robust performance under model misspecification. For more details, see Hellstern and Shojaie (2025) <doi:10.48550/arXiv.2511.19761>.
Converts results from the manymome package, presented in Cheung and Cheung (2023) <doi:10.3758/s13428-023-02224-z>, to publication-ready tables.
Multisite causal mediation analysis using the methods proposed by Qin and Hong (2017) <doi:10.3102/1076998617694879>, Qin, Hong, Deutsch, and Bein (2019) <doi:10.1111/rssa.12446>, and Qin, Deutsch, and Hong (2021) <doi:10.1002/pam.22268>. It enables causal mediation analysis in multisite trials, in which individuals are assigned to a treatment or a control group at each site. It allows for estimation and hypothesis testing for not only the population average but also the between-site variance of direct and indirect effects transmitted through one single mediator or two concurrent (conditionally independent) mediators. This strategy conveniently relaxes the assumption of no treatment-by-mediator interaction while greatly simplifying the outcome model specification without invoking strong distributional assumptions. This package also provides a function that can further incorporate a sample weight and a nonresponse weight for multisite causal mediation analysis in the presence of complex sample and survey designs and non-random nonresponse, to enhance both the internal validity and external validity. The package also provides a weighting-based balance checking function for assessing the remaining overt bias.
Allows users to conduct multivariate distance matrix regression using analytic p-values and compute measures of effect size. For details on the method, see McArtor, Lubke, & Bergeman (2017) <doi:10.1007/s11336-016-9527-8>.
The goal of midr is to provide a model-agnostic method for interpreting and explaining black-box predictive models by creating a globally interpretable surrogate model. The package implements Maximum Interpretation Decomposition (MID), a functional decomposition technique that finds an optimal additive approximation of the original model. This approximation is achieved by minimizing the squared error between the predictions of the black-box model and the surrogate model. The theoretical foundations of MID are described in Iwasawa & Matsumori (2025) [Forthcoming], and the package itself is detailed in Asashiba et al. (2025) <doi:10.48550/arXiv.2506.08338>.
Conducts and simulates the MABOUST design, including making interim decisions to stop a treatment for inferiority or stop the trial early for superiority or equivalency.
This package provides a HTML widget rendering the Monaco editor. The Monaco editor is the code editor which powers VS Code'. It is particularly well developed for JavaScript'. In addition to the built-in features of the Monaco editor, the widget allows to prettify multiple languages, to view the HTML rendering of Markdown code, and to view and resize SVG images.
Encodes several methods for performing Mendelian randomization analyses with summarized data. Summarized data on genetic associations with the exposure and with the outcome can be obtained from large consortia. These data can be used for obtaining causal estimates using instrumental variable methods.
Collection of the state of the art multi-label resampling algorithms. The objective of these algorithms is to achieve balance in multi-label datasets.
Quantify the causal effect of a binary exposure on a binary outcome with adjustment for multiple biases. The functions can simultaneously adjust for any combination of uncontrolled confounding, exposure/outcome misclassification, and selection bias. The underlying method generalizes the concept of combining inverse probability of selection weighting with predictive value weighting. Simultaneous multi-bias analysis can be used to enhance the validity and transparency of real-world evidence obtained from observational, longitudinal studies. Based on the work from Paul Brendel, Aracelis Torres, and Onyebuchi Arah (2023) <doi:10.1093/ije/dyad001>.
Scalable Bayesian clustering of categorical datasets. The package implements a hierarchical Dirichlet (Process) mixture of multinomial distributions. It is thus a probabilistic latent class model (LCM) and can be used to reduce the dimensionality of hierarchical data and cluster individuals into latent classes. It can automatically infer an appropriate number of latent classes or find k classes, as defined by the user. The model is based on a paper by Dunson and Xing (2009) <doi:10.1198/jasa.2009.tm08439>, but implements a scalable variational inference algorithm so that it is applicable to large datasets. It is described and tested in the accompanying paper by Ahlmann-Eltze and Yau (2018) <doi:10.1109/DSAA.2018.00068>.
This package provides users to call MATLAB from using the "system" command. Allows users to submit lines of code or MATLAB m files. This is in comparison to R.matlab', which creates a MATLAB server.
Generate a monochrome palette from a starting colour for a specified number of colours. The package can also be used to display colour palettes in the plot window, with or without hex codes and colour labels.
Estimation and inference for multiple kink quantile regression for longitudinal data and the i.i.d data. A bootstrap restarting iterative segmented quantile algorithm is proposed to estimate the multiple kink quantile regression model conditional on a given number of change points. The number of kinks is also allowed to be unknown. In such case, the backward elimination algorithm and the bootstrap restarting iterative segmented quantile algorithm are combined to select the number of change points based on a quantile BIC. For longitudinal data, we also develop the GEE estimator to incorporate the within-subject correlations. A score-type based test statistic is also developed for testing the existence of kink effect. The package is based on the paper, ``Wei Zhong, Chuang Wan and Wenyang Zhang (2022). Estimation and inference for multikink quantile regression, JBES and ``Chuang Wan, Wei Zhong, Wenyang Zhang and Changliang Zou (2022). Multi-kink quantile regression for longitudinal data with application to progesterone data analysis, Biometrics".
This package provides a simple and trustworthy methodology for the analysis of misreported continuous time series. See Moriña, D, Fernández-Fontelo, A, Cabaña, A, Puig P. (2021) <arXiv:2003.09202v2>.
We implement a surrogate modeling algorithm to guide simulation-based sample size planning. The method is described in detail in our paper (Zimmer & Debelak (2023) <doi:10.1037/met0000611>). It supports multiple study design parameters and optimization with respect to a cost function. It can find optimal designs that correspond to a desired statistical power or that fulfill a cost constraint. We also provide a tutorial paper (Zimmer et al. (2023) <doi:10.3758/s13428-023-02269-0>).
This package provides a set of core functions for handling medical device event data in the context of post-market surveillance, pharmacovigilance, signal detection and trending, and regulatory reporting. Primary inputs are data on events by device and data on exposures by device. Outputs include: standardized device-event and exposure datasets, defined analyses, and time series.
This package provides functions for diagnostic meta-analysis. Next to basic analysis and visualization the bivariate Model of Reitsma et al. (2005) that is equivalent to the HSROC of Rutter & Gatsonis (2001) can be fitted. A new approach based to diagnostic meta-analysis of Holling et al. (2012) is also available. Standard methods like summary, plot and so on are provided.