Companion package of Carrion-i-Silvestre & Sansó (2023): "Generalized Extreme Value Approximation to the CUMSUMQ Test for Constant Unconditional Variance in Heavy-Tailed Time Series". It implements the Modified Iterative Cumulative Sum of Squares Algorithm, which is an extension of the Iterative Cumulative Sum of Squares (ICSS) Algorithm of Inclan and Tiao (1994), and it checks for changes in the unconditional variance of a time series controlling for the tail index of the underlying distribution. The fourth order moment is estimated non-parametrically to avoid the size problems when the innovations are non-Gaussian (see, Sansó et al., 2004). Critical values and p-values are generated using a Generalized Extreme Value distribution approach. References Carrion-i-Silvestre J.J & Sansó A (2023) <https://www.ub.edu/irea/working_papers/2023/202309.pdf>. Inclan C & Tiao G.C (1994) <doi:10.1080/01621459.1994.10476824>, Sansó A & Aragó V & Carrion-i-Silvestre J.L (2004) <https://dspace.uib.es/xmlui/bitstream/handle/11201/152078/524035.pdf>.

Allows the user to generate a friendly user interface for emails sending. The user can choose from the most popular free email services ('Gmail', Outlook', Yahoo') and his default email application. The package is a wrapper for the Mailtoui JavaScript library. See <https://mailtoui.com/#menu> for more information.

Functions, data sets and examples for the book: Yves Croissant (2025) "Microeconometrics with R", Chapman and Hall/CRC The R Series <doi:10.1201/9781003100263>. The package includes a set of estimators for models used in microeconometrics, especially for count data and limited dependent variables. Test functions include score test, Hausman test, Vuong test, Sargan test and conditional moment test. A small subset of the data set used in the book is also included.

Multi Calculator of different scores to measure adherence to Mediterranean Diet, to compute them in nutriepidemiological data. Additionally, a sample dataset of this kind of data is provided, and some other minor tools useful in epidemiological studies.

Estimate genetic linkage maps for markers on a single chromosome (or in a single linkage group) from pairwise recombination fractions or intermarker distances using weighted metric multidimensional scaling. The methods are suitable for autotetraploid as well as diploid populations. Options for assessing the fit to a known map are also provided. Methods are discussed in detail in Preedy and Hackett (2016) <doi:10.1007/s00122-016-2761-8>.

This package implements a regularized Bayesian estimator that optimizes the estimation of between-group coefficients for multilevel latent variable models by minimizing mean squared error (MSE) and balancing variance and bias. The package provides more reliable estimates in scenarios with limited data, offering a robust solution for accurate parameter estimation in two-level latent variable models. It is designed for researchers in psychology, education, and related fields who face challenges in estimating between-group effects under small sample sizes and low intraclass correlation coefficients. The package includes comprehensive S3 methods for result objects: print(), summary(), coef(), se(), vcov(), confint(), as.data.frame(), dim(), length(), names(), and update() for enhanced usability and integration with standard R workflows. Dashuk et al. (2025a) <doi:10.1017/psy.2025.10045> derived the optimal regularized Bayesian estimator; Dashuk et al. (2025b) <doi:10.1007/s41237-025-00264-7> extended it to the multivariate case; and Luedtke et al. (2008) <doi:10.1037/a0012869> formalized the two-level latent variable framework.

The Molecular Signatures Database ('MSigDB') is one of the most widely used and comprehensive databases of gene sets for performing gene set enrichment analysis <doi:10.1016/j.cels.2015.12.004>. The msig package provides you with powerful, easy-to-use and flexible query functions for the MsigDB database. There are 2 query modes in the msig package: online query and local query. Both queries contain 2 steps: gene set name and gene. The online search is divided into 2 modes: registered search and non-registered browse. For registered search, email that you registered should be provided. Local queries can be made from local database, which can be updated by msig_update() function.

High-performance MongoDB client based on mongo-c-driver and jsonlite'. Includes support for aggregation, indexing, map-reduce, streaming, encryption, enterprise authentication, and GridFS. The online user manual provides an overview of the available methods in the package: <https://jeroen.github.io/mongolite/>.

This package provides a new way to predict time series using the marginal distribution table in the absence of the significance of traditional models.

Collection of functions to perform fixed and random-effects multivariate and univariate meta-analysis and meta-regression.

This package provides a graphical user interface to apply an advanced method optimization algorithm to various sampling and analysis instruments. This includes generating experimental designs, uploading and viewing data, and performing various analyses to determine the optimal method. Details of the techniques used in this package are published in Gamble, Granger, & Mannion (2024) <doi:10.1021/acs.analchem.3c05763>.

This package performs Modal Clustering (MAC) including Hierarchical Modal Clustering (HMAC) along with their parallel implementation (PHMAC) over several processors. These model-based non-parametric clustering techniques can extract clusters in very high dimensions with arbitrary density shapes. By default clustering is performed over several resolutions and the results are summarised as a hierarchical tree. Associated plot functions are also provided. There is a package vignette that provides many examples. This version adheres to CRAN policy of not spanning more than two child processes by default.

These guidelines are meant to provide a pragmatic, yet rigorous, help to drug developers and decision makers, since they are shaped by three fundamental ingredients: the clinically determined margin of detriment on OS that is unacceptably high (delta null); the benefit on OS that is plausible given the mechanism of action of the novel intervention (delta alt); and the quantity of information (i.e. survival events) it is feasible to accrue given the clinical and drug development setting. The proposed guidelines facilitate transparent discussions between stakeholders focusing on the risks of erroneous decisions and what might be an acceptable trade-off between power and the false positive error rate.

Dealing with neutrosophic data in single valued form using score, accuracy and certainty functions to calculate ranks of Single Valued Neutrosophic Set (SVNS), also to calculate the Mann-Whitney test, and making a post-hoc test after rejecting the null hypothesis using the Neutrosophic Statistics Kruskal-Wallis test. For more information see Miari, Mahmoud; Anan, Mohamad Taher; Zeina, Mohamed Bisher(2022) <https://digitalrepository.unm.edu/nss_journal/vol51/iss1/60/>.

To calculate the Minimal Clinically Important Difference by applying the Anchor-based method and the Response shift effect by applying the Then-Test method.

Hypothesis tests for multivariate data. Tests for one and two mean vectors, multivariate analysis of variance, tests for one, two or more covariance matrices. References include: Mardia K.V., Kent J.T. and Bibby J.M. (1979). Multivariate Analysis. ISBN: 978-0124712522. London: Academic Press.

This package provides a web-based graphical user interface to provide the basic steps of a machine learning workflow. It uses the functionalities of the mlr3 framework.

Flexible and informed regression with Multiple Change Points. mcp can infer change points in means, variances, autocorrelation structure, and any combination of these, as well as the parameters of the segments in between. All parameters are estimated with uncertainty and prediction intervals are supported - also near the change points. mcp supports hypothesis testing via Savage-Dickey density ratio, posterior contrasts, and cross-validation. mcp is described in Lindeløv (submitted) <doi:10.31219/osf.io/fzqxv> and generalizes the approach described in Carlin, Gelfand, & Smith (1992) <doi:10.2307/2347570> and Stephens (1994) <doi:10.2307/2986119>.

Makes Mapbox GL JS <https://docs.mapbox.com/mapbox-gl-js/api/>, an open source JavaScript library that uses WebGL to render interactive maps, available within R via the htmlwidgets package. Visualizations can be used from the R console, in R Markdown documents and in Shiny apps.

Dataset and functions from the meta-analysis published in Medicine & Science in Sports & Exercise. It contains all the data and functions to reproduce the analysis. "Effectiveness of HIIE versus MICT in Improving Cardiometabolic Risk Factors in Health and Disease: A Meta-analysis". Felipe Mattioni Maturana, Peter Martus, Stephan Zipfel, Andreas M Nieà (2020) <doi:10.1249/MSS.0000000000002506>.

This package provides tools for creating agents with persistent state using R6 classes <https://cran.r-project.org/package=R6> and the ellmer package <https://cran.r-project.org/package=ellmer>. Tracks prompts, messages, and agent metadata for reproducible, multi-turn large language model sessions.

Fits the Bayesian multinomial probit model via Markov chain Monte Carlo. The multinomial probit model is often used to analyze the discrete choices made by individuals recorded in survey data. Examples where the multinomial probit model may be useful include the analysis of product choice by consumers in market research and the analysis of candidate or party choice by voters in electoral studies. The MNP package can also fit the model with different choice sets for each individual, and complete or partial individual choice orderings of the available alternatives from the choice set. The estimation is based on the efficient marginal data augmentation algorithm that is developed by Imai and van Dyk (2005). "A Bayesian Analysis of the Multinomial Probit Model Using the Data Augmentation." Journal of Econometrics, Vol. 124, No. 2 (February), pp. 311-334. <doi:10.1016/j.jeconom.2004.02.002> Detailed examples are given in Imai and van Dyk (2005). "MNP: R Package for Fitting the Multinomial Probit Model." Journal of Statistical Software, Vol. 14, No. 3 (May), pp. 1-32. <doi:10.18637/jss.v014.i03>.

Colour palettes and helper functions for visualising Mycobacterium tuberculosis genomic and epidemiological data with ggplot2 and ggtree'. The package provides predefined palettes, scale functions, tree/cladogram helpers, and convenient preview tools to ensure consistent branding in pathogen-omics visualisations. The palettes were developed as part of the mycolorsTB project <https://github.com/PathoGenOmics-Lab/mycolorsTB>.

This package provides a new method to implement clustering from multiple modality data of certain samples, the function M2SMjF() jointly factorizes multiple similarity matrices into a shared sub-matrix and several modality private sub-matrices, which is further used for clustering. Along with this method, we also provide function to calculate the similarity matrix and function to evaluate the best cluster number from the original data.