Exploratory data analysis and manipulation functions for multi- label data sets along with an interactive Shiny application to ease their use.

This package provides functions that (1) fit multivariate discrete distributions, (2) generate random numbers from multivariate discrete distributions, and (3) run regression and penalized regression on the multivariate categorical response data. Implemented models include: multinomial logit model, Dirichlet multinomial model, generalized Dirichlet multinomial model, and negative multinomial model. Making the best of the minorization-maximization (MM) algorithm and Newton-Raphson method, we derive and implement stable and efficient algorithms to find the maximum likelihood estimates. On a multi-core machine, multi-threading is supported.

The rapid screening of effective and optimal therapies from large numbers of candidate combinations, as well as exploring subgroup efficacy, remains challenging, which necessitates innovative, integrated, and efficient trial designs(Yuan, Y., et al. (2016) <doi:10.1002/sim.6971>). MIDAS-2 package enables quick and continuous screening of promising combination strategies and exploration of their subgroup effects within a unified platform design framework. We used a regression model to characterize the efficacy pattern in subgroups. Information borrowing was applied through Bayesian hierarchical model to improve trial efficiency considering the limited sample size in subgroups(Cunanan, K. M., et al. (2019) <doi:10.1177/1740774518812779>). MIDAS-2 provides an adaptive drug screening and subgroup exploring framework to accelerate immunotherapy development in an efficient, accurate, and integrated fashion(Wathen, J. K., & Thall, P. F. (2017) <doi: 10.1177/1740774517692302>).

This package provides a client for interacting with magma', the data warehouse of the UCSF Data Library'. magmaR includes functions for querying and downloading data from magma', in order to enable working with such data in R, as well as for uploading local data to magma'.

Computes the posterior model probabilities for standard meta-analysis models (null model vs. alternative model assuming either fixed- or random-effects, respectively). These posterior probabilities are used to estimate the overall mean effect size as the weighted average of the mean effect size estimates of the random- and fixed-effect model as proposed by Gronau, Van Erp, Heck, Cesario, Jonas, & Wagenmakers (2017, <doi:10.1080/23743603.2017.1326760>). The user can define a wide range of non-informative or informative priors for the mean effect size and the heterogeneity coefficient. Moreover, using pre-compiled Stan models, meta-analysis with continuous and discrete moderators with Jeffreys-Zellner-Siow (JZS) priors can be fitted and tested. This allows to compute Bayes factors and perform Bayesian model averaging across random- and fixed-effects meta-analysis with and without moderators. For a primer on Bayesian model-averaged meta-analysis, see Gronau, Heck, Berkhout, Haaf, & Wagenmakers (2021, <doi:10.1177/25152459211031256>).

Functionalities for facilitating systematic reviews, data extractions, and meta-analyses. It includes a GUI (graphical user interface) to help screen the abstracts and titles of bibliographic data; tools to assign screening effort across multiple collaborators/reviewers and to assess inter- reviewer reliability; tools to help automate the download and retrieval of journal PDF articles from online databases; figure and image extractions from PDFs; web scraping of citations; automated and manual data extraction from scatter-plot and bar-plot images; PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) flow diagrams; simple imputation tools to fill gaps in incomplete or missing study parameters; generation of random effects sizes for Hedges d, log response ratio, odds ratio, and correlation coefficients for Monte Carlo experiments; covariance equations for modelling dependencies among multiple effect sizes (e.g., effect sizes with a common control); and finally summaries that replicate analyses and outputs from widely used but no longer updated meta-analysis software (i.e., metawin). Funding for this package was supported by National Science Foundation (NSF) grants DBI-1262545 and DEB-1451031. CITE: Lajeunesse, M.J. (2016) Facilitating systematic reviews, data extraction and meta-analysis with the metagear package for R. Methods in Ecology and Evolution 7, 323-330 <doi:10.1111/2041-210X.12472>.

Exports two functions implementing multi-way clustering using the method suggested by Cameron, Gelbach, & Miller (2011) and cluster (or block) bootstrapping for estimating variance-covariance matrices. Normal one and two-way clustering matches the results of other common statistical packages. Missing values are handled transparently and rudimentary parallelization support is provided.

This package performs treatment assignment for (field) experiments considering available, possibly multivariate and continuous, information (covariates, observable characteristics), that is: forms balanced treatment groups, according to the minMSE-method as proposed by Schneider and Schlather (2017) <DOI:10419/161931>.

This package performs maximal interaction two-mode clustering, permutation tests, scree plots, and interaction visualizations for bicluster analysis. See Ahmed et al. (2025) <doi:10.17605/OSF.IO/AWGXB>, Ahmed et al. (2023) <doi:10.1007/s00357-023-09434-2>, Ahmed et al. (2021) <doi:10.1007/s11634-021-00441-y>.

Estimates random effect latent measurement models, wherein the loadings, residual variances, intercepts, latent means, and latent variances all vary across groups. The random effect variances of the measurement parameters are then modeled using a hierarchical inclusion model, wherein the inclusion of the variances (i.e., whether it is effectively zero or non-zero) is informed by similar parameters (of the same type, or of the same item). This additional hierarchical structure allows the evidence in favor of partial invariance to accumulate more quickly, and yields more certain decisions about measurement invariance. Martin, Williams, and Rast (2020) <doi:10.31234/osf.io/qbdjt>.

This package provides functions and datasets used in the book: Fernandez-Casal, R., Costa, J. and Oviedo-de la Fuente, M. (2024) "Metodos predictivos de aprendizaje estadistico" <https://rubenfcasal.github.io/aprendizaje_estadistico/>.

Uses multiple AUCs to select a combination of predictors when the outcome has multiple (ordered) levels and the focus is discriminating one particular level from the others. This method is most naturally applied to settings where the outcome has three levels. (Meisner, A, Parikh, CR, and Kerr, KF (2017) <http://biostats.bepress.com/uwbiostat/paper423/>.).

Compute bootstrap confidence intervals for the adjusted Schnabel and Schumacher-Eschmeyer multi-visit mark-recapture estimators based on Dettloff (2023) <doi:10.1016/j.fishres.2023.106756>.

This package implements a regularized Bayesian estimator that optimizes the estimation of between-group coefficients for multilevel latent variable models by minimizing mean squared error (MSE) and balancing variance and bias. The package provides more reliable estimates in scenarios with limited data, offering a robust solution for accurate parameter estimation in two-level latent variable models. It is designed for researchers in psychology, education, and related fields who face challenges in estimating between-group effects under small sample sizes and low intraclass correlation coefficients. The package includes comprehensive S3 methods for result objects: print(), summary(), coef(), se(), vcov(), confint(), as.data.frame(), dim(), length(), names(), and update() for enhanced usability and integration with standard R workflows. Dashuk et al. (2025a) <doi:10.1017/psy.2025.10045> derived the optimal regularized Bayesian estimator; Dashuk et al. (2025b) <doi:10.1007/s41237-025-00264-7> extended it to the multivariate case; and Luedtke et al. (2008) <doi:10.1037/a0012869> formalized the two-level latent variable framework.

Metadynamics is a state of the art biomolecular simulation technique. Plumed Tribello, G.A. et al. (2014) <doi:10.1016/j.cpc.2013.09.018> program makes it possible to perform metadynamics using various simulation codes. The results of metadynamics done in Plumed can be analyzed by metadynminer'. The package metadynminer reads 1D and 2D metadynamics hills files from Plumed package. As an addendum, metadynaminer3d is used to visualize 3D hills. It uses a fast algorithm by Hosek, P. and Spiwok, V. (2016) <doi:10.1016/j.cpc.2015.08.037> to calculate a free energy surface from hills. Minima can be located and plotted on the free energy surface. Free energy surfaces and minima can be plotted to produce publication quality images.

This package provides programmatic access to the Meetup GraphQL API (<https://www.meetup.com/graphql/>), enabling users to retrieve information about groups, events, and members from Meetup (<https://www.meetup.com/>). Supports authentication via OAuth2 and includes functions for common queries and data manipulation tasks.

Fitting multivariate response models with random effects on one or two levels; whereby the (one-dimensional) random effect represents a latent variable approximating the multivariate space of outcomes, after possible adjustment for covariates. The method is particularly useful for multivariate, highly correlated outcome variables with unobserved heterogeneities. Applications include regression with multivariate responses, as well as multivariate clustering or ranking problems. See Zhang and Einbeck (2024) <doi:10.1007/s42519-023-00357-0>.

Bayesian inference analysis for bivariate meta-analysis of diagnostic test studies using integrated nested Laplace approximation with INLA. A purpose built graphic user interface is available. The installation of R package INLA is compulsory for successful usage. The INLA package can be obtained from <https://www.r-inla.org>. We recommend the testing version, which can be downloaded by running: install.packages("INLA", repos=c(getOption("repos"), INLA="https://inla.r-inla-download.org/R/testing"), dep=TRUE).

This package provides functions to classify mass spectra in known categories and to determine discriminant mass-to-charge values (m/z). Includes easy-to-use preprocessing pipelines for Matrix Assisted Laser Desorption Ionisation - Time Of Flight Mass Spectrometry (MALDI-TOF) mass spectra, methods to select discriminant m/z from labelled libraries, and tools to predict categories (species, phenotypes, etc.) from selected features. Also provides utilities to build design matrices from peak intensities and labels. While this package was developed with the aim of identifying very similar species or phenotypes of bacteria from MALDI-TOF MS, the functions of this package can also be used to classify other categories associated to mass spectra; or from mass spectra obtained with other mass spectrometry techniques. Parallelized processing and optional C++-accelerated functions are available (notably to deal with large datasets) from version 0.5.0. If you use this package in your research, please cite the associated publication (<doi:10.1016/j.eswa.2025.128796>). For a comprehensive guide, additional applications, and detailed examples, see <https://github.com/agodmer/MSclassifR_examples>.

Quickly make tables of descriptive statistics (i.e., counts, means, confidence intervals) for continuous variables. This package is designed to work in a Tidyverse pipeline, and consideration has been given to get results from R to Microsoft Word ® with minimal pain.

Facilitates the incorporation of biological processes in biogeographical analyses. It offers conveniences in fitting, comparing and extrapolating models of biological processes such as physiology and phenology. These spatial extrapolations can be informative by themselves, but also complement traditional correlative species distribution models, by mixing environmental and process-based predictors. Caetano et al (2020) <doi:10.1111/oik.07123>.

This package provides a companion to the Chinese book ``Modern Statistical Graphics''.

This package provides estimation and leave-one-cluster-out jackknife standard errors for four longitudinal cluster-randomized trial estimands: horizontal individual average treatment effect (h-iATE), horizontal cluster average treatment effect (h-cATE), vertical individual average treatment effect (v-iATE), and vertical cluster-period average treatment effect (v-cATE), using unadjusted and augmented (model-robust standardization) estimators. The working model may be fit using linear mixed models for continuous outcomes or generalized estimating equations and generalized linear mixed models for binary outcomes. Period inclusion for aggregation is determined automatically: only periods with both treated and control clusters are included in the construction of the marginal means and treatment effect contrasts. See Fang et al. (2025) <doi:10.48550/arXiv.2507.17190>.

Calculate the financial impact of using a churn model in terms of cost, revenue, profit and return on investment.