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Spontaneous adverse event reports have a high potential for detecting adverse drug reactions. However, due to their dimension, the analysis of such databases requires statistical methods. We propose to use a logistic regression whose sparsity is viewed as a model selection challenge. Since the model space is huge, a Metropolis-Hastings algorithm carries out the model selection by maximizing the BIC criterion.
This package provides comorbidity classification algorithms such as the Pediatric Complex Chronic Conditions (PCCC), Charlson, and Elixhauser indices, supports longitudinal comorbidity flagging across encounters, and includes utilities for working with medical coding schemas such as the International Classification of Diseases (ICD).
Calculate and visualise the financial impact of using a classification model, such as a churn model, to target customers. Provides cost, revenue, profit and return-on-investment curves as a function of the share of customers targeted, cumulative gains and lift, marginal profit per bin, and confusion-matrix based payoff across probability thresholds. Also includes ggplot2 autoplot() methods and an interactive shiny application for exploring the results.
Create marimekko (mosaic) plots as a ggplot2 layer. Column widths encode marginal proportions of one categorical variable and segment heights encode conditional proportions of a second categorical variable.
This package implements Mander & Thompson's (2010) <doi:10.1016/j.cct.2010.07.008> methods for two-stage designs optimal under the alternative hypothesis for phase II [cancer] trials. Also provides an implementation of Simon's (1989) <doi:10.1016/0197-2456(89)90015-9> original methodology and allows exploration of the operating characteristics of sub-optimal designs.
Framework for building modular Monte Carlo risk analysis models. It extends the capabilities of mc2d to facilitate working with multiple risk pathways, variates and scenarios. It provides tools to organize risk analysis in independent flexible modules, align multivariate mcnodes, automate the creation of mcnodes, visualise model structure, assess convergence, and perform sensitivity analysis. For more details see Ciria (2026) <https://nataliaciria.com/mcmodule/>.
Extends multiverse package (Sarma A., Kale A., Moon M., Taback N., Chevalier F., Hullman J., Kay M., 2021) <doi:10.31219/osf.io/yfbwm>, which allows users perform to create explorable multiverse analysis in R. This extension provides an additional level of abstraction to the multiverse package with the aim of creating user friendly syntax to researchers, educators, and students in statistics. The mverse syntax is designed to allow piping and takes hints from the tidyverse grammar. The package allows users to define and inspect multiverse analysis using familiar syntax in R.
This package performs the MRFA approach proposed by Sung et al. (2020) <doi:10.1080/01621459.2019.1595630> to fit and predict nonlinear regression problems, particularly for large-scale and high-dimensional problems. The application includes deterministic or stochastic computer experiments, spatial datasets, and so on.
When a network is partially observed (here, NAs in the adjacency matrix rather than 1 or 0 due to missing information between node pairs), it is possible to account for the underlying process that generates those NAs. missSBM', presented in Barbillon, Chiquet and Tabouy (2022) <doi:10.18637/jss.v101.i12>, adjusts the popular stochastic block model from network data sampled under various missing data conditions, as described in Tabouy, Barbillon and Chiquet (2019) <doi:10.1080/01621459.2018.1562934>.
Providing the kubernetes-like class ManagedCloudProvider as a child class of the CloudProvider class in the DockerParallel package. The class is able to manage the cloud instance made by the non-kubernetes cloud service. For creating a provider for the non-kubernetes cloud service, the developer needs to define a reference class inherited from ManagedCloudProvider and define the method for the generics runDockerWorkerContainers(), getDockerWorkerStatus() and killDockerWorkerContainers(). For more information, please see the vignette in this package and <https://CRAN.R-project.org/package=DockerParallel>.
This package provides a collection of functions for computations and visualizations of microbial pan-genomes.
Additional documentation, a package vignette and regression tests for package mlt.
Exploratory and predictive methods for the analysis of several blocks of variables measured on the same individuals.
Dimension reduction for multivariate data of extreme events with a PCA like procedure as described in Reinbott, Janà en, (2024), <doi:10.48550/arXiv.2408.10650>. Tools for necessary transformations of the data are provided.
Estimation, inference and diagnostics for Univariate Autoregressive Markov Switching Models for Linear and Generalized Models. Distributions for the series include gaussian, Poisson, binomial and gamma cases. The EM algorithm is used for estimation (see Perlin (2012) <doi:10.2139/ssrn.1714016>).
This package provides tools to conduct Monte Carlo simulations under different conditions (e.g., varying sample size, data normality) for structural equation models (SEMs). Data can be simulated based on user-defined factor loadings and correlations, with optional non-normality added via Fleishman's power method (1978) <doi:10.1007/BF02293811>. Once generated, models can be estimated using lavaan'. This package facilitates testing model performance across multiple simulation scenarios. When data generation is completed (or when generated data sets are given) model tests can also be run. Please cite as "Orçan, F. (2021). MonteCarloSEM An R Package to Simulate Data for SEM. International Journal of Assessment Tools in Education, 8 (3), 704-713.".
This package provides a tool for implementing so called deft approach (see Fisher, David J., et al. (2017) <DOI:10.1136/bmj.j573>) and model visualization.
This package provides a utility library to facilitate the generalization of statistical methods built on a regression framework. Package developers can use modelObj methods to initiate a regression analysis without concern for the details of the regression model and the method to be used to obtain parameter estimates. The specifics of the regression step are left to the user to define when calling the function. The user of a function developed within the modelObj framework creates as input a modelObj that contains the model and the R methods to be used to obtain parameter estimates and to obtain predictions. In this way, a user can easily go from linear to non-linear models within the same package.
The number of biological databases is growing rapidly, but different databases use different IDs to refer to the same biological entity. The inconsistency in IDs impedes the integration of various types of biological data. To resolve the problem, we developed MantaID', a data-driven, machine-learning based approach that automates identifying IDs on a large scale. The MantaID model's prediction accuracy was proven to be 99%, and it correctly and effectively predicted 100,000 ID entries within two minutes. MantaID supports the discovery and exploitation of ID patterns from large quantities of databases. (e.g., up to 542 biological databases). An easy-to-use freely available open-source software R package, a user-friendly web application, and API were also developed for MantaID to improve applicability. To our knowledge, MantaID is the first tool that enables an automatic, quick, accurate, and comprehensive identification of large quantities of IDs, and can therefore be used as a starting point to facilitate the complex assimilation and aggregation of biological data across diverse databases.
Identifies the optimal number of clusters by calculating the similarity between two clustering methods at the same number of clusters using the corrected indices of Rand and Jaccard as described in Albatineh and Niewiadomska-Bugaj (2011). The number of clusters at which the index attain its maximum more frequently is a candidate for being the optimal number of clusters.
This package provides utilities for reading and processing microdata from Spanish official statistics with R.
Assessment of inconsistency in meta-analysis by calculating the Decision Inconsistency index (DI) and the Across-Studies Inconsistency (ASI) index. These indices quantify inconsistency taking into account outcome-level decision thresholds.
This package provides methods for the analysis of how ecological drivers affect the multifunctionality of an ecosystem based on methods of Byrnes et al. 2016 <doi:10.1111/2041-210X.12143> and Byrnes et al. 2022 <doi:10.1101/2022.03.17.484802>. Most standard methods in the literature are implemented (see vignettes) in a tidy format.
Computes the optimal number of regions (or subdivisions) and their position in serial structures without a priori assumptions and to visualize the results. After reducing data dimensionality with the built-in function for data ordination, regions are fitted as segmented linear regressions along the serial structure. Every region boundary position and increasing number of regions are iteratively fitted and the best model (number of regions and boundary positions) is selected with an information criterion. This package expands on the previous regions package (Jones et al. (2018) <doi:10.1126/science.aar3126>) with improved computation and more fitting and plotting options.