This package provides a new method to implement clustering from multiple modality data of certain samples, the function M2SMjF() jointly factorizes multiple similarity matrices into a shared sub-matrix and several modality private sub-matrices, which is further used for clustering. Along with this method, we also provide function to calculate the similarity matrix and function to evaluate the best cluster number from the original data.

Overcomes one of the major challenges in mobile (passive) sensing, namely being able to pre-process the raw data that comes from a mobile sensing app, specifically m-Path Sense <https://m-path.io>. The main task of mpathsenser is therefore to read m-Path Sense JSON files into a database and provide several convenience functions to aid in data processing.

Analyzes non-normal data via the Multiple Comparison Procedures and Modeling approach (MCP-Mod). Many functions rely on the DoseFinding package. This package makes it so the user does not need to provide or calculate the mu vector and S matrix. Instead, the user typically supplies the data in its raw form, and this package will calculate the needed objects and passes them into the DoseFinding functions. If the user wishes to primarily use the functions provided in the DoseFinding package, a singular function (prepareGen()) will provide mu and S. The package currently handles power analysis and the MCP-Mod procedure for negative binomial, Poisson, and binomial data. The MCP-Mod procedure can also be applied to survival data, but power analysis is not available. Bretz, F., Pinheiro, J. C., and Branson, M. (2005) <doi:10.1111/j.1541-0420.2005.00344.x>. Buckland, S. T., Burnham, K. P. and Augustin, N. H. (1997) <doi:10.2307/2533961>. Pinheiro, J. C., Bornkamp, B., Glimm, E. and Bretz, F. (2014) <doi:10.1002/sim.6052>.

This package contains functions to estimate the proportion of effects stronger than a threshold of scientific importance (function prop_stronger), to nonparametrically characterize the distribution of effects in a meta-analysis (calib_ests, pct_pval), to make effect size conversions (r_to_d, r_to_z, z_to_r, d_to_logRR), to compute and format inference in a meta-analysis (format_CI, format_stat, tau_CI), to scrape results from existing meta-analyses for re-analysis (scrape_meta, parse_CI_string, ci_to_var).

Given a set of data points, a clustering is defined as a disjoint partition where each pair of sets in a partition has no overlapping elements. This package provides 25 methods that play a role somewhat similar to distance or metric that measures similarity of two clusterings - or partitions. For a more detailed description, see Meila, M. (2005) <doi:10.1145/1102351.1102424>.

This function allows to generate two biological conditions synthetic microarray dataset which has similar behavior to those currently observed with common platforms. User provides a subset of parameters. Available default parameters settings can be modified.

Transferring over a code base from Matlab to R is often a repetitive and inefficient use of time. This package provides a translator for Matlab / Octave code into R code. It does some syntax changes, but most of the heavy lifting is in the function changes since the languages are so similar. Options for different data structures and the functions that can be changed are given. The Matlab code should be mostly in adherence to the standard style guide but some effort has been made to accommodate different number of spaces and other small syntax issues. This will not make the code more R friendly and may not even run afterwards. However, the rudimentary syntax, base function and data structure conversion is done quickly so that the maintainer can focus on changes to the design structure.

Clean, prepare, and aggregate surveillance data for public health analysis. Provides structural data cleaning and standardisation (clean_the_nest()), age categorisation against ~50 published schemes with publication-ready labelling (preening()), time-unit aggregation with zero-filling and seasonal awareness (roost()), joint aggregation of several linked event dates (e.g. onset, admission, ICU, complication, fatality) into one table of comparable rate columns (flyway()), under-ascertainment correction via a stratified, time-varying multiplier factor supplied directly, derived by the ratio (multiplier) method, or derived by inverting an externally sourced severity rate (e.g. an infection-fatality-rate anchor) against an observed severity ratio (corncrake()), comorbidity detection from ICD-10-AM clinical coding (plumage()), vaccine coverage data construction (brood()), hash-based de-identification (molting()), and relinking of previously de-identified data (homing()). brood() produces a brood_df object supporting two population models: pre-aggregated denominators (population_model = "pre_aggregated") and record-level cohort designs (population_model = "cohort"). The cohort model handles single time-point coverage snapshots, interrupted time series analysis via a built-in sweep returning monthly coverage rates (time_series = TRUE), and birth cohort designs with person-time computation. This cohort/time-series coverage model was applied in Roughan et al. (2026) <doi:10.33321/cdi.2026.50.031> to estimate infant immunisation coverage against respiratory syncytial virus over an 18-month period. Both wide format (one row per person with dose columns, from starling'::murmuration()) and long format (one row per dose) are accepted. corncrake() returns both a point-corrected count and uncertainty bounds wherever they can be derived, including the inverse relationship between a severity-anchored factor and the bounds of its own reference rate. Built for Australian public health surveillance practice but not specific to it -- see individual function documentation for notes on non-Australian use (e.g. Northern Hemisphere season boundaries).

This package provides tools for data analysis with multivariate Bayesian structural time series (MBSTS) models. Specifically, the package provides facilities for implementing general structural time series models, flexibly adding on different time series components (trend, season, cycle, and regression), simulating them, fitting them to multivariate correlated time series data, conducting feature selection on the regression component.

Procedures to simulate, estimate and diagnose MGARCH processes of BEKK and multivariate GJR (bivariate asymmetric GARCH model) specification.

This package provides a simple in-memory, LRU cache that can be wrapped around any function to memoize it. The cache is keyed on a hash of the input data (using digest') or on pointer equivalence. Also includes a generic hashmap object that can key on any object type.

This package provides samplers for various matrix variate distributions: Wishart, inverse-Wishart, normal, t, inverted-t, Beta type I, Beta type II, Gamma, confluent hypergeometric. Allows to simulate the noncentral Wishart distribution without the integer restriction on the degrees of freedom.

Fast imputations under the object-oriented programming paradigm. Moreover there are offered a few functions built to work with popular R packages such as data.table or dplyr'. The biggest improvement in time performance can be achieved for a calculation where a grouping variable is used. A single evaluation of a quantitative model for the multiple imputations is another major enhancement. A new major improvement is one of the fastest predictive mean matching in the R world because of presorting and binary search.

An ensemble classifier for multiclass classification. This is a novel classifier that natively works as an ensemble. It projects data on a large number of matrices, and uses very simple classifiers on each of these projections. The results are then combined, ideally via Dempster-Shafer Calculus.

This package implements the MEC-TX (MEchanistic Clustering - Treatment eXposure) framework for encoding, clustering, and survival analysis of real-world oncology treatment timelines. Provides functions for normalising medication records, computing treatment intervals, performing k-means clustering in PCA space, assigning line-of-therapy labels, and comparing survival outcomes across treatment groups. Designed for use with registry-based cohorts such as the ORIEN AVATAR dataset. Methods follow the digital-twin framework described in Dhrubo and Spakowicz (2026) <https://github.com/spakowiczlab/mec-tx>. treatment timelines using the MEC-TX digital-twin framework.

This package provides functions to perform all steps of genome-wide association meta-analysis for studying Genotype x Environment interactions, from collecting the data to the manhattan plot. The procedure accounts for the potential correlation between studies. In addition to the Fixed and Random models, one can investigate the relationship between QTL effects and some qualitative or quantitative covariate via the test of contrast and the meta-regression, respectively. The methodology is available from: (De Walsche, A., et al. (2025) \doi10.1371/journal.pgen.1011553).

This package implements model-robust standardization for cluster-randomized trials (CRTs). Provides functions that standardize user-specified regression models to estimate marginal treatment effects. The targets include the cluster-average and individual-average treatment effects, with utilities for variance estimation and example simulation datasets. Methods are described in Li, Tong, Fang, Cheng, Kahan, and Wang (2025) <doi:10.1002/sim.70270>.

The unique function of this package allows representing in a single graph the relative occurrence and co-occurrence of events measured in a sample. As examples, the package was applied to describe the occurrence and co-occurrence of different species of bacterial or viral symbionts infecting arthropods at the individual level. The graphics allows determining the prevalence of each symbiont and the patterns of multiple infections (i.e. how different symbionts share or not the same individual hosts). We named the package after the famous painter as the graphical output recalls Mondrianâ s paintings.

There are three different modules: (1) model fitting and selection using a set of the most commonly used equations describing developmental responses to temperature helped by already existing R packages ('rTPC') and nonlinear regression model functions from nls.multstart (Padfield et al. 2021, <doi:10.1111/2041-210X.13585>), with visualization of model predictions to guide ecological criteria for model selection; (2) calculation of suitability thermal limits, which consist on a temperature interval delimiting the optimal performance zone or suitability; and (3) climatic data extraction and visualization inspired on previous research (Taylor et al. 2019, <doi:10.1111/1365-2664.13455>), with either exportable rasters, static map images or html, interactive maps.

This package provides functions to facilitate model-based clustering of nodes in a network in a mixture of experts setting, which incorporates covariate information on the nodes in the modelling process. Isobel Claire Gormley and Thomas Brendan Murphy (2010) <doi:10.1016/j.stamet.2010.01.002>.

Maximum likelihood estimation for generalized linear mixed models via Monte Carlo EM. For a description of the algorithm see Brian S. Caffo, Wolfgang Jank and Galin L. Jones (2005) <DOI:10.1111/j.1467-9868.2005.00499.x>.

Calculate different metrics based on aquatic macroinvertebrate density data (individuals per square meter) to assess water quality (Prat N et al. 2009).

Evaluate whether a microbiome sample is a mixture of two samples, by fitting a model for the number of read counts as a function of single nucleotide polymorphism (SNP) allele and the genotypes of two potential source samples. Lobo et al. (2021) <doi:10.1093/g3journal/jkab308>.

This package provides a set of functions to obtain modified score test for generalized linear models.