This package provides routines for multivariate measurement error correction. Includes procedures for linear, logistic and Cox regression models. Bootstrapped standard errors and confidence intervals can be obtained for corrected estimates.

This package implements the generalization of the Shapiro-Wilk test for multivariate normality proposed by Villasenor-Alva and Gonzalez-Estrada (2009).

Estimation of k-Order time-varying Mixed Graphical Models and mixed VAR(p) models via elastic-net regularized neighborhood regression. For details see Haslbeck & Waldorp (2020) <doi:10.18637/jss.v093.i08>.

Finds the Maximum Likelihood (ML) Estimate of the mean vector and variance-covariance matrix for multivariate normal data with missing values.

Nonparametric approach to estimate the location of block boundaries (change-points) of non-overlapping blocks in a random symmetric matrix which consists of random variables whose distribution changes from block to block. BRAULT Vincent, OUADAH Sarah, SANSONNET Laure and LEVY-LEDUC Celine (2017) <doi:10.1016/j.jmva.2017.12.005>.

This package provides functions to interpolate irregularly and regularly spaced data using Multilevel B-spline Approximation (MBA). Functions call portions of the SINTEF Multilevel B-spline Library written by à yvind Hjelle which implements methods developed by Lee, Wolberg and Shin (1997; <doi:10.1109/2945.620490>).

Many useful functions and extensions for dealing with meteorological data in the tidy data framework. Extends ggplot2 for better plotting of scalar and vector fields and provides commonly used analysis methods in the atmospheric sciences.

This package provides readers for easy and consistent importing of Mouse Genome Informatics (MGI) report files: <https://www.informatics.jax.org/downloads/reports/index.html>. These data are provided by Baldarelli RM, Smith CL, Ringwald M, Richardson JE, Bult CJ, Mouse Genome Informatics Group (2024) <doi:10.1093/genetics/iyae031>.

Distance between multivariate t distributions, as presented by N. Bouhlel and D. Rousseau (2023) <doi:10.1109/LSP.2023.3324594>.

Frequently one needs a convenient way to build and tune several models in one go.The goal is to provide a number of machine learning convenience functions. It provides the ability to build, tune and obtain predictions of several models in one function. The models are built using functions from caret with easier to read syntax. Kuhn(2014) <doi:10.48550/arXiv.1405.6974>.

Extends the mlr3 ML framework with methods for spatial objects. Data storage and prediction are supported for packages terra', raster and stars'.

This package provides tools for the analysis of psychophysical data in R. This package allows to estimate the Point of Subjective Equivalence (PSE) and the Just Noticeable Difference (JND), either from a psychometric function or from a Generalized Linear Mixed Model (GLMM). Additionally, the package allows plotting the fitted models and the response data, simulating psychometric functions of different shapes, and simulating data sets. For a description of the use of GLMMs applied to psychophysical data, refer to Moscatelli et al. (2012).

Different examples and methods for testing (including different proposals described in Ameijeiras-Alonso et al., 2019 <DOI:10.1007/s11749-018-0611-5>) and exploring (including the mode tree, mode forest and SiZer) the number of modes using nonparametric techniques <DOI:10.18637/jss.v097.i09>.

This package is deprecated. Please use redatamx instead. Provides an API to work with Redatam (see <https://redatam.org>) databases in both formats: RXDB (new format) and DICX (old format) and running Redatam programs written in SPC language. It's a wrapper around Redatam core and provides functions to open/close a database (redatam_open()/redatam_close()), list entities and variables from the database (redatam_entities(), redatam_variables()) and execute a SPC program and gets the results as data frames (redatam_query(), redatam_run()).

Find dark genes. These genes are often disregarded due to no detected mutation or differential expression, but are important in coordinating the functionality in cancer networks.

Estimate and test inter-generational social mobility effect on an outcome with cross-sectional or longitudinal data.

Applying the methodology from Manuel et al. to estimate parameters using a matched case control data with a mismeasured exposure variable that is accompanied by instrumental variables (Submitted).

Fast imputations under the object-oriented programming paradigm. Moreover there are offered a few functions built to work with popular R packages such as data.table or dplyr'. The biggest improvement in time performance can be achieved for a calculation where a grouping variable is used. A single evaluation of a quantitative model for the multiple imputations is another major enhancement. A new major improvement is one of the fastest predictive mean matching in the R world because of presorting and binary search.

This package provides tools for univariate and multivariate generalized linear models with model averaging and null model technique.

Fits the neighboring models of a fitted structural equation model and assesses the model uncertainty of the fitted model based on BIC posterior probabilities (BPP), using the method presented in Wu, Cheung, and Leung (2020) <doi:10.1080/00273171.2019.1574546>. See Pesigan, Cheung, Wu, Chang, and Leung (2026) <doi:10.3758/s13428-025-02921-x> for an introduction to the package.

Administrative Boundaries of Spain at several levels (Autonomous Communities, Provinces, Municipalities) based on the GISCO Eurostat database <https://ec.europa.eu/eurostat/web/gisco> and CartoBase SIANE from Instituto Geografico Nacional <https://www.ign.es/>. It also provides a leaflet plugin and the ability of downloading and processing static tiles.

This package provides helper functions, metadata utilities, and workflows for administering and managing databases on the Motherduck cloud platform. Some features require a Motherduck account (<https://motherduck.com/>).

With high-dimensional omics features, repeated measure ANOVA leads to longitudinal gene-environment interaction studies that have intra-cluster correlations, outlying observations and structured sparsity arising from the ANOVA design. In this package, we have developed robust sparse Bayesian mixed effect models tailored for the above studies (Fan et al. (2025) <doi:10.1093/jrsssc/qlaf027>). An efficient Gibbs sampler has been developed to facilitate fast computation. The Markov chain Monte Carlo algorithms of the proposed and alternative methods are efficiently implemented in C++'. The development of this software package and the associated statistical methods have been partially supported by an Innovative Research Award from Johnson Cancer Research Center, Kansas State University.

An approach to identifies metabolic biomarker signature for metabolic data by discovering predictive metabolite for predicting survival and classifying patients into risk groups. Classifiers are constructed as a linear combination of predictive/important metabolites, prognostic factors and treatment effects if necessary. Several methods were implemented to reduce the metabolomics matrix such as the principle component analysis of Wold Svante et al. (1987) <doi:10.1016/0169-7439(87)80084-9> , the LASSO method by Robert Tibshirani (1998) <doi:10.1002/(SICI)1097-0258(19970228)16:4%3C385::AID-SIM380%3E3.0.CO;2-3>, the elastic net approach by Hui Zou and Trevor Hastie (2005) <doi:10.1111/j.1467-9868.2005.00503.x>. Sensitivity analysis on the quantile used for the classification can also be accessed to check the deviation of the classification group based on the quantile specified. Large scale cross validation can be performed in order to investigate the mostly selected predictive metabolites and for internal validation. During the evaluation process, validation is accessed using the hazard ratios (HR) distribution of the test set and inference is mainly based on resampling and permutations technique.