This package provides a simple tool to quantify the amount of transmission of an infectious disease of interest occurring within and between population groups. bumblebee uses counts of observed directed transmission pairs, identified phylogenetically from deep-sequence data or from epidemiological contacts, to quantify transmission flows within and between population groups accounting for sampling heterogeneity. Population groups might include: geographical areas (e.g. communities, regions), demographic groups (e.g. age, gender) or arms of a randomized clinical trial. See the bumblebee website for statistical theory, documentation and examples <https://magosil86.github.io/bumblebee/>.

This package provides a set of functions to select the optimal block-length for a dependent bootstrap (block-bootstrap). Includes the Hall, Horowitz, and Jing (1995) <doi:10.1093/biomet/82.3.561> subsampling-based cross-validation method, the Politis and White (2004) <doi:10.1081/ETC-120028836> Spectral Density Plug-in method, including the Patton, Politis, and White (2009) <doi:10.1080/07474930802459016> correction, and the Lahiri, Furukawa, and Lee (2007) <doi:10.1016/j.stamet.2006.08.002> nonparametric plug-in method, with a corresponding set of S3 plot methods.

Regression for data too large to fit in memory. This package functions exactly like the biglm package, but works with later versions of R.

Perform the Benford's Analysis to a data set in order to evaluate if it contains human fabricated data. For more details on the method see Moreau, 2021, Model Assist. Statist. Appl., 16 (2021) 73â 79. <doi:10.3233/MAS-210517>.

This package provides the estimation algorithm to perform the demand estimation described in Berry, Levinsohn and Pakes (1995) <DOI:10.2307/2171802> . The routine uses analytic gradients and offers a large number of implemented integration methods and optimization routines.

Implementation of the BRIk, FABRIk and FDEBRIk algorithms to initialise k-means. These methods are intended for the clustering of multivariate and functional data, respectively. They make use of the Modified Band Depth and bootstrap to identify appropriate initial seeds for k-means, which are proven to be better options than many techniques in the literature. Torrente and Romo (2021) <doi:10.1007/s00357-020-09372-3> It makes use of the functions kma and kma.similarity, from the archived package fdakma, by Alice Parodi et al.

This package provides a Bayesian variable selection approach using continuous spike and slab prior distributions. The prior choices here are motivated by the shrinking and diffusing priors studied in Narisetty & He (2014) <DOI:10.1214/14-AOS1207>.

High performance principal component analysis routines that operate directly on bigmemory::big.matrix objects. The package avoids materialising large matrices in memory by streaming data through BLAS and LAPACK kernels and provides helpers to derive scores, loadings, correlations, and contribution diagnostics, including utilities that stream results into bigmemory'-backed matrices for file-based workflows. Additional interfaces expose scalable singular value decomposition, robust PCA, and robust SVD algorithms so that users can explore large matrices while tempering the influence of outliers. Scalable principal component analysis is also implemented, Elgamal, Yabandeh, Aboulnaga, Mustafa, and Hefeeda (2015) <doi:10.1145/2723372.2751520>.

Computation of large covariance matrices having a block structure up to a permutation of their columns and rows from a small number of samples with respect to the dimension of the matrix. The method is described in the paper Perrot-Dockès et al. (2019) <arXiv:1806.10093>.

Boldness-recalibration maximally spreads out probability predictions while maintaining a user specified level of calibration, facilitated the brcal() function. Supporting functions to assess calibration via Bayesian and Frequentist approaches, Maximum Likelihood Estimator (MLE) recalibration, Linear in Log Odds (LLO)-adjust via any specified parameters, and visualize results are also provided. Methodological details can be found in Guthrie & Franck (2024) <doi:10.1080/00031305.2024.2339266>.

This package provides a suite of functions for finance, including the estimation of variance matrices via a statistical factor model or Ledoit-Wolf shrinkage.

Laplace approximations and penalized B-splines are combined for fast Bayesian inference in latent Gaussian models. The routines can be used to fit survival models, especially proportional hazards and promotion time cure models (Gressani, O. and Lambert, P. (2018) <doi:10.1016/j.csda.2018.02.007>). The Laplace-P-spline methodology can also be implemented for inference in (generalized) additive models (Gressani, O. and Lambert, P. (2021) <doi:10.1016/j.csda.2020.107088>). See the associated website for more information and examples.

An interface to the Bayesian Weighted Sums model implemented in RStan'. It estimates the summed effect of multiple, often moderately to highly correlated, continuous predictors. Its applications can be found in analysis of exposure mixtures. The model was proposed by Hamra, Maclehose, Croen, Kauffman, and Newschaffer (2021) <doi:10.3390/ijerph18041373>. This implementation includes an extension to model binary outcome.

Easy estimation of Bayesian multilevel mediation models with Stan.

This package provides methods for mediation analysis with missing data and non-normal data are implemented. For missing data, four methods are available: Listwise deletion, Pairwise deletion, Multiple imputation, and Two Stage Maximum Likelihood algorithm. For MI and TS-ML, auxiliary variables can be included to handle missing data. For handling non-normal data, bootstrap and two-stage robust methods can be used. Technical details of the methods can be found in Zhang and Wang (2013, <doi:10.1007/s11336-012-9301-5>), Zhang (2014, <doi:10.3758/s13428-013-0424-0>), and Yuan and Zhang (2012, <doi:10.1007/s11336-012-9282-4>).

An all-encompassing R toolkit designed to streamline the process of calling various bioinformatics software and then performing data analysis and visualization in R. With blit', users can easily integrate a wide array of bioinformatics command line tools into their workflows, leveraging the power of R for sophisticated data manipulation and graphical representation.

Description: Provides streamlined tools for retrieving sequences from NCBI, performing sequence alignments (pairwise and multiple), and building phylogenetic trees. Implements the Needleman-Wunsch algorithm for global alignment (Needleman & Wunsch (1970) <doi:10.1016/0022-2836(70)90057-4>), Smith-Waterman for local alignment (Smith & Waterman (1981) <doi:10.1016/0022-2836(81)90087-5>), and Neighbor-Joining for tree construction (Saitou & Nei (1987) <doi:10.1093/oxfordjournals.molbev.a040454>).

Set of functions to calculate Benthic Biotic Indices from composition data, obtained whether from morphotaxonomic inventories or sequencing data. Based on reference ecological weights publicly available for a set of commonly used marine biotic indices, such as AMBI (A Marine Biotic Index, Borja et al., 2000) <doi:10.1016/S0025-326X(00)00061-8> NSI (Norwegian Sensitivity Index) and ISI (Indicator Species Index) (Rygg 2013, <ISBN:978-82-577-6210-0>). It provides the ecological quality status of the samples based on each BBI as well as the normalized Ecological Quality Ratio.

This package provides a box compatible custom language parser for the languageserver package to provide completion and signature hints in code editors.

This package provides functions for behavior genetics analysis, including variance component model identification [Hunter et al. (2021) <doi:10.1007/s10519-021-10055-x>], calculation of relatedness coefficients using path-tracing methods [Wright (1922) <doi:10.1086/279872>; McArdle & McDonald (1984) <doi:10.1111/j.2044-8317.1984.tb00802.x>], inference of relatedness, pedigree conversion, and simulation of multi-generational family data [Lyu et al. (2024) <doi:10.1101/2024.12.19.629449>]. For a full overview, see [Garrison et al. (2024) <doi:10.21105/joss.06203>].

This package provides methods and tools for estimating, simulating and forecasting of so-called BEKK-models (named after Baba, Engle, Kraft and Kroner) based on the fast Berndtâ Hallâ Hallâ Hausman (BHHH) algorithm described in Hafner and Herwartz (2008) <doi:10.1007/s00184-007-0130-y>. For an overview, we refer the reader to Fülle et al. (2024) <doi:10.18637/jss.v111.i04>.

This package provides tools to analyze binary graph objects.

Fit Bayesian multivariate GARCH models using Stan for full Bayesian inference. Generate (weighted) forecasts for means, variances (volatility) and correlations. Currently DCC(P,Q), CCC(P,Q), pdBEKK(P,Q), and BEKK(P,Q) parameterizations are implemented, based either on a multivariate gaussian normal or student-t distribution. DCC and CCC models are based on Engle (2002) <doi:10.1198/073500102288618487> and Bollerslev (1990). The BEKK parameterization follows Engle and Kroner (1995) <doi:10.1017/S0266466600009063> while the pdBEKK as well as the estimation approach for this package is described in Rast et al. (2020) <doi:10.31234/osf.io/j57pk>. The fitted models contain rstan objects and can be examined with rstan functions.

Used for Bayesian mediation analysis based on Bayesian additive Regression Trees (BART). The analysis method is described in Yu and Li (2025) "Mediation Analysis with Bayesian Additive Regression Trees", submitted for publication.