This package implements methods for centrality related analyses of networks. While the package includes the possibility to build more than 20 indices, its main focus lies on index-free assessment of centrality via partial rankings obtained by neighborhood-inclusion or positional dominance. These partial rankings can be analyzed with different methods, including probabilistic methods like computing expected node ranks and relative rank probabilities (how likely is it that a node is more central than another?). The methodology is described in depth in the vignettes and in Schoch (2018) <doi:10.1016/j.socnet.2017.12.003>.

Downloading and organizing plant presence and percent cover data from the National Ecological Observatory Network <https://www.neonscience.org>.

This package provides automated methods for generating initial parameter estimates in population pharmacokinetic modeling. The pipeline integrates adaptive single-point methods, naive pooled graphic approaches, noncompartmental analysis methods, and parameter sweeping across pharmacokinetic models. It estimates residual unexplained variability using either data-driven or fixed-fraction approaches and assigns pragmatic initial values for inter-individual variability. These strategies are designed to improve model robustness and convergence in nlmixr2 workflows. For more details see Huang Z, Fidler M, Lan M, Cheng IL, Kloprogge F, Standing JF (2025) <doi:10.1007/s10928-025-10000-z>.

Extends the classical Newman studentized range statistic in various ways that can be applied to genome-scale transcriptomic or other expression data.

Each dataset contains scores for every game during a specific season of the NHL.

This package implements a method that builds the coefficients of a polynomial model that performs almost equivalently as a given neural network (densely connected). This is achieved using Taylor expansion at the activation functions. The obtained polynomial coefficients can be used to explain features (and their interactions) importance in the neural network, therefore working as a tool for interpretability or eXplainable Artificial Intelligence (XAI). See Morala et al. 2021 <doi:10.1016/j.neunet.2021.04.036>, and 2023 <doi:10.1109/TNNLS.2023.3330328>.

Renders dynamic network data from networkDynamic objects as movies, interactive animations, or other representations of changing relational structures and attributes.

Utilities for Natural Language Processing.

Calculate NOS (node overlap and segregation) and the associated metrics described in Strona and Veech (2015) <doi:10.1111/2041-210X.12395> and Strona et al. (2018) <doi:10.1111/ecog.03447>. The functions provided in the package enable assessment of structural patterns ranging from complete node segregation to perfect nestedness in a variety of network types. In addition, they provide a measure of network modularity.

Calculate Overall Survival or Recurrence-Free Survival for breast cancer patients, using NHS Predict'. The time interval for the estimation can be set up to 15 years, with default at 10. Incremental therapy benefits are estimated for hormone therapy, chemotherapy, trastuzumab, and bisphosphonates. An additional function, suited for SCAN audits, features a more user-friendly version of the code, with fewer inputs, but necessitates the correct standardised inputs. This work is not affiliated with the development of NHS Predict and its underlying statistical model. Details on NHS Predict can be found at: <doi:10.1186/bcr2464>. The web version of NHS Predict': <https://breast.predict.nhs.uk/>. A small dataset of 50 fictional patient observations is provided for the purpose of running examples with the main two functions, and an additional dataset is provided for running example with the dedicated SCAN function.

Model-based clustering of high-dimensional non-negative data that follow Generalized Negative Binomial distribution. All functions in this package applies to either continuous or integer data. Correlation between variables are allowed, while samples are assumed to be independent.

This package provides a comprehensive toolkit for calculating and visualizing Nitrogen Use Efficiency (NUE) indicators in agricultural research. The package implements 23 parameters categorized into fertilizer-based, plant-based, soil-based, isotope-based, ecology-based, and system-based indicators based on Congreves et al. (2021) <doi:10.3389/fpls.2021.637108>. Key features include vectorized calculations for paired-plot experimental designs, batch processing capabilities for handling large datasets, and built-in visualization tools using ggplot2'. Designed to streamline the workflow from raw agronomic data to publication-ready metrics and plots.

An implementation of some of the core network package functionality based on a simplified data structure that is faster in many research applications. This package is designed for back-end use in the statnet family of packages, including EpiModel'. Support is provided for binary and weighted, directed and undirected, bipartite and unipartite networks; no current support for multigraphs, hypergraphs, or loops.

This package provides utility functions and objects for Extreme Value Analysis. These include probability functions with their exact derivatives w.r.t. the parameters that can be used for estimation and inference, even with censored observations. The transformations exchanging the two parameterizations of Peaks Over Threshold (POT) models: Poisson-GP and Point-Process are also provided with their derivatives.

This package provides efficient implementation of the Narrowest-Over-Threshold methodology for detecting an unknown number of change-points occurring at unknown locations in one-dimensional data following deterministic signal + noise model. Currently implemented scenarios are: piecewise-constant signal, piecewise-constant signal with a heavy-tailed noise, piecewise-linear signal, piecewise-quadratic signal, piecewise-constant signal and with piecewise-constant variance of the noise. For details, see Baranowski, Chen and Fryzlewicz (2019) <doi:10.1111/rssb.12322>.

Acquires and synthesizes soil carbon fluxes at sites located in the National Ecological Observatory Network (NEON). Provides flux estimates and associated uncertainty as well as key environmental measurements (soil water, temperature, CO2 concentration) that are used to compute soil fluxes.

With this package, it is possible to compute nonparametric simultaneous confidence intervals for relative contrast effects in the unbalanced one way layout. Moreover, it computes simultaneous p-values. The simultaneous confidence intervals can be computed using multivariate normal distribution, multivariate t-distribution with a Satterthwaite Approximation of the degree of freedom or using multivariate range preserving transformations with Logit or Probit as transformation function. 2 sample comparisons can be performed with the same methods described above. There is no assumption on the underlying distribution function, only that the data have to be at least ordinal numbers. See Konietschke et al. (2015) <doi:10.18637/jss.v064.i09> for details.

Represent network or igraph objects whose vertices can be represented by features in an sf object as a network graph surmising a sf plot. Fits into ggplot2 grammar.

This package provides a toolkit for medical records data analysis. The naryn package implements an efficient data structure for storing medical records, and provides a set of functions for data extraction, manipulation and analysis.

Quantifies and removes technical noise from high-throughput sequencing data. Two approaches are used, one based on the count matrix, and one using the alignment BAM files directly. Contains several options for every step of the process, as well as tools to quality check and assess the stability of output.

This package performs analysis of one-way multivariate data, for small samples using Nonparametric techniques. Using approximations for ANOVA Type, Wilks Lambda, Lawley Hotelling, and Bartlett Nanda Pillai Test statics, the package compares the multivariate distributions for a single explanatory variable. The comparison is also performed using a permutation test for each of the four test statistics. The package also performs an all-subsets algorithm regarding variables and regarding factor levels.

This package provides a nonvisual procedure for screening time series for nonstationarity in the context of intensive longitudinal designs, such as ecological momentary assessments. The method combines two diagnostics: one for detecting trends (based on the split R-hat statistic from Bayesian convergence diagnostics) and one for detecting changes in variance (a novel extension inspired by Levene's test). This approach allows researchers to efficiently and reproducibly detect violations of the stationarity assumption, especially when visual inspection of many individual time series is impractical. The procedure is suitable for use in all areas of research where time series analysis is central. For a detailed description of the method and its validation through simulations and empirical application, see Zitzmann, S., Lindner, C., Lohmann, J. F., & Hecht, M. (2024) "A Novel Nonvisual Procedure for Screening for Nonstationarity in Time Series as Obtained from Intensive Longitudinal Designs" <https://www.researchgate.net/publication/384354932_A_Novel_Nonvisual_Procedure_for_Screening_for_Nonstationarity_in_Time_Series_as_Obtained_from_Intensive_Longitudinal_Designs>.

This package performs variable selection in sparse negative binomial GLARMA (Generalised Linear Autoregressive Moving Average) models. For further details we refer the reader to the paper Gomtsyan (2023), <arXiv:2307.00929>.

Perform non-bipartite matching and matched randomization. A "bipartite" matching utilizes two separate groups, e.g. smokers being matched to nonsmokers or cases being matched to controls. A "non-bipartite" matching creates mates from one big group, e.g. 100 hospitals being randomized for a two-arm cluster randomized trial or 5000 children who have been exposed to various levels of secondhand smoke and are being paired to form a greater exposure vs. lesser exposure comparison. At the core of a non-bipartite matching is a N x N distance matrix for N potential mates. The distance between two units expresses a measure of similarity or quality as mates (the lower the better). The gendistance() and distancematrix() functions assist in creating this. The nonbimatch() function creates the matching that minimizes the total sum of distances between mates; hence, it is referred to as an "optimal" matching. The assign.grp() function aids in performing a matched randomization. Note bipartite matching can be performed using the prevent option in gendistance()'.