Subsampling methods for big data under different models and assumptions. Starting with linear regression and leading to Generalised Linear Models, softmax regression, and quantile regression. Specifically, the model-robust subsampling method proposed in Mahendran, A., Thompson, H., and McGree, J. M. (2023) <doi:10.1007/s00362-023-01446-9>, where multiple models can describe the big data, and the subsampling framework for potentially misspecified Generalised Linear Models in Mahendran, A., Thompson, H., and McGree, J. M. (2025) <doi:10.48550/arXiv.2510.05902>.

Creation and selection of N-way Partial Least Squares (NPLS) models. Selection of the optimal number of components can be done using ncrossreg(). NPLS was originally described by Rasmus Bro, see <doi:10.1002/%28SICI%291099-128X%28199601%2910%3A1%3C47%3A%3AAID-CEM400%3E3.0.CO%3B2-C>.

Estimators and variance estimators tailored to the NILS hierarchical design (Adler et al. 2020, <https://res.slu.se/id/publ/105630>; Grafström et al. 2023, <https://res.slu.se/id/publ/128235>). The National Inventories of Landscapes in Sweden (NILS) is a long-term national monitoring program that collects, analyses and presents data on Swedish nature, covering both common and rare habitats <https://www.slu.se/om-slu/organisation/institutioner/skoglig-resurshushallning/miljoanalys/nils/>.

This package provides routines to compute normalised prediction distribution errors, a metric designed to evaluate non-linear mixed effect models such as those used in pharmacokinetics and pharmacodynamics.

The Nordklim dataset 1.0 is a unique and useful achievement for climate analysis. It includes observations of twelve different climate elements from more than 100 stations in the Nordic region, in time span over 100 years. The project contractors were NORDKLIM/NORDMET on behalf of the National meteorological services in Denmark (DMI), Finland (FMI), Iceland (VI), Norway (DNMI) and Sweden (SMHI).

Next-Generation Clustered Heat Maps (NG-CHMs) allow for dynamic exploration of heat map data in a web browser. NGCHM allows users to create both stand-alone HTML files containing a Next-Generation Clustered Heat Map, and .ngchm files to view in the NG-CHM viewer. See Ryan MC, Stucky M, et al (2020) <doi:10.12688/f1000research.20590.2> for more details.

Multiple and generalized nonparametric regression using smoothing spline ANOVA models and generalized additive models, as described in Helwig (2020) <doi:10.4135/9781526421036885885>. Includes support for Gaussian and non-Gaussian responses, smoothers for multiple types of predictors (including random intercepts), interactions between smoothers of mixed types, eight different methods for smoothing parameter selection, and flexible tools for diagnostics, inference, and prediction.

This package provides nonparametric CUSUM tests for detecting changes in possibly serially dependent univariate or low-dimensional multivariate observations. Retrospective tests sensitive to changes in the expectation, the variance, the covariance, the autocovariance, the distribution function, Spearman's rho, Kendall's tau, Gini's mean difference, and the copula are provided, as well as a test for detecting changes in the distribution of independent block maxima (with environmental studies in mind). The package also contains a test sensitive to changes in the autocopula and a combined test of stationarity sensitive to changes in the distribution function and the autocopula. The latest additions are an open-end sequential test based on the retrospective CUSUM statistic that can be used for monitoring changes in the mean of possibly serially dependent univariate observations, as well as closed-end and open-end sequential tests based on empirical distribution functions that can be used for monitoring changes in the contemporary distribution of possibly serially dependent univariate or low-dimensional multivariate observations.

Counts syllables in character vectors for English words. Imputes syllables as the number of vowel sequences for words not found.

This package provides a framework for systematic exploration of association rules (Agrawal et al., 1994, <https://www.vldb.org/conf/1994/P487.PDF>), contrast patterns (Chen, 2022, <doi:10.48550/arXiv.2209.13556>), emerging patterns (Dong et al., 1999, <doi:10.1145/312129.312191>), subgroup discovery (Atzmueller, 2015, <doi:10.1002/widm.1144>), and conditional correlations (Hájek, 1978, <doi:10.1007/978-3-642-66943-9>). User-defined functions may also be supplied to guide custom pattern searches. Supports both crisp (Boolean) and fuzzy data. Generates candidate conditions expressed as elementary conjunctions, evaluates them on a dataset, and inspects the induced sub-data for statistical, logical, or structural properties such as associations, correlations, or contrasts. Includes methods for visualization of logical structures and supports interactive exploration through integrated Shiny applications.

Network meta-analysis tools based on contrast-based approach using the multivariate meta-analysis and meta-regression models (Noma et al. (2025) <doi:10.1101/2025.09.15.25335823>). Comprehensive analysis tools for network meta-analysis and meta-regression (e.g., synthesis analysis, ranking analysis, and creating league table) are available through simple commands. For inconsistency assessment, the local and global inconsistency tests based on the Higgins design-by-treatment interaction model are available. In addition, the side-splitting methods and Jackson's random inconsistency model can be applied. Standard graphical tools for network meta-analysis, including network plots, ranked forest plots, and transitivity analyses, are also provided. For the synthesis analyses, the Noma-Hamura's improved REML (restricted maximum likelihood)-based methods (Noma et al. (2023) <doi:10.1002/jrsm.1652> <doi:10.1002/jrsm.1651>) are adopted as the default methods.

This package provides null model algorithms for categorical and quantitative community ecology data. Extends classic binary null models (e.g., curveball', swap') to work with categorical data. Provides a stratified randomization framework for continuous data.

Given a network (e.g. a food web), estimates several network indices. These include: Ascendency network indices, Direct and indirect dependencies, Effective measures, Environ network indices, General network indices, Pathway analysis, Network uncertainty indices and constraint efficiencies and the trophic level and omnivory indices of food webs.

Perform a stratified weighted log-rank test in a randomized controlled trial. Tests can be visualized as a difference in average score on the two treatment arms. These methods are described in Magirr and Burman (2018) <doi:10.48550/arXiv.1807.11097>, Magirr (2020) <doi:10.48550/arXiv.2007.04767>, and Magirr and Jimenez (2022) <doi:10.48550/arXiv.2201.10445>.

Training of neural networks using backpropagation, resilient backpropagation with (Riedmiller, 1994) or without weight backtracking (Riedmiller and Braun, 1993) or the modified globally convergent version by Anastasiadis et al. (2005). The package allows flexible settings through custom-choice of error and activation function. Furthermore, the calculation of generalized weights (Intrator O & Intrator N, 1993) is implemented.

Setup, run and analyze NetLogo (<https://www.netlogo.org>) model simulations in R'. nlrx experiments use a similar structure as NetLogos Behavior Space experiments. However, nlrx offers more flexibility and additional tools for running and analyzing complex simulation designs and sensitivity analyses. The user defines all information that is needed in an intuitive framework, using class objects. Experiments are submitted from R to NetLogo via XML files that are dynamically written, based on specifications defined by the user. By nesting model calls in future environments, large simulation design with many runs can be executed in parallel. This also enables simulating NetLogo experiments on remote high performance computing machines. In order to use this package, Java and NetLogo (>= 5.3.1) need to be available on the executing system.

Regress network responses (both directed and undirected) onto covariates of interest that may be actor-, relation-, or network-valued. In addition, compute principled variance estimates of the coefficients assuming that the errors are jointly exchangeable. Missing data is accommodated. Additionally implements building and inversion of covariance matrices under joint exchangeability, and generates random covariance matrices from this class. For more detail on methods, see Marrs, Fosdick, and McCormick (2017) <arXiv:1701.05530>.

This package implements the navigated weighting (NAWT) proposed by Katsumata (2020) <arXiv:2005.10998>, which improves the inverse probability weighting by utilizing estimating equations suitable for a specific pre-specified parameter of interest (e.g., the average treatment effects or the average treatment effects on the treated) in propensity score estimation. It includes the covariate balancing propensity score proposed by Imai and Ratkovic (2014) <doi:10.1111/rssb.12027>, which uses covariate balancing conditions in propensity score estimation. The point estimate of the parameter of interest as well as coefficients for propensity score estimation and their uncertainty are produced using the M-estimation. The same functions can be used to estimate average outcomes in missing outcome cases.

Naive discriminative learning implements learning and classification models based on the Rescorla-Wagner equations and their equilibrium equations.

Estimates the relative transmission probabilities between cases in an infectious disease outbreak or cluster using naive Bayes. Included are various functions to use these probabilities to estimate transmission parameters such as the generation/serial interval and reproductive number as well as finding the contribution of covariates to the probabilities and visualizing results. The ideal use is for an infectious disease dataset with metadata on the majority of cases but more informative data such as contact tracing or pathogen whole genome sequencing on only a subset of cases. For a detailed description of the methods see Leavitt et al. (2020) <doi:10.1093/ije/dyaa031>.

Stochastic collapsed variational inference on mixed-membership stochastic blockmodel for networks, incorporating node-level predictors of mixed-membership vectors, as well as dyad-level predictors. For networks observed over time, the model defines a hidden Markov process that allows the effects of node-level predictors to evolve in discrete, historical periods. In addition, the package offers a variety of utilities for exploring results of estimation, including tools for conducting posterior predictive checks of goodness-of-fit and several plotting functions. The package implements methods described in Olivella, Pratt and Imai (2019) Dynamic Stochastic Blockmodel Regression for Social Networks: Application to International Conflicts', available at <https://www.santiagoolivella.info/pdfs/socnet.pdf>.

This package provides a set of techniques that can be used to develop, validate, and implement automated classifiers. A powerful tool for transforming raw data into meaningful information, ncodeR (Shaffer, D. W. (2017) Quantitative Ethnography. ISBN: 0578191687) is designed specifically for working with big data: large document collections, logfiles, and other text data.

Several methods have been developed to integrate structural equation modeling techniques with network data analysis to examine the relationship between network and non-network data. Both node-based and edge-based information can be extracted from the network data to be used as observed variables in structural equation modeling. To facilitate the application of these methods, model specification can be performed in the familiar syntax of the lavaan package, ensuring ease of use for researchers. Technical details and examples can be found at <https://bigsem.psychstat.org>.

Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation solving is by compiled C code provided in the rxode2 package (Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).