This package contains methods described by Dennis Helsel in his book "Statistics for Censored Environmental Data using Minitab and R" (2011) and courses and videos at <https://practicalstats.com>. This package incorporates functions of NADA and adds new functionality.

Multiple and generalized nonparametric regression using smoothing spline ANOVA models and generalized additive models, as described in Helwig (2020) <doi:10.4135/9781526421036885885>. Includes support for Gaussian and non-Gaussian responses, smoothers for multiple types of predictors (including random intercepts), interactions between smoothers of mixed types, eight different methods for smoothing parameter selection, and flexible tools for diagnostics, inference, and prediction.

This package provides the Arctic Ice Studio's Nord and Group of Seven inspired colour palettes for use with ggplot2 via custom functions.

Conducts Bayesian Hypothesis tests of a point null hypothesis against a two-sided alternative using Non-local Alternative Prior (NAP) for one- and two-sample z- and t-tests (Pramanik and Johnson, 2022). Under the alternative, the NAP is assumed on the standardized effects size in one-sample tests and on their differences in two-sample tests. The package considers two types of NAP densities: (1) the normal moment prior, and (2) the composite alternative. In fixed design tests, the functions calculate the Bayes factors and the expected weight of evidence for varied effect size and sample size. The package also provides a sequential testing framework using the Sequential Bayes Factor (SBF) design. The functions calculate the operating characteristics (OC) and the average sample number (ASN), and also conducts sequential tests for a sequentially observed data.

Clinical reporting figures require to use consistent colors and configurations. As a part of the Roche open-source clinical reporting project, namely the NEST project, the nestcolor package specifies the color code and default theme with specifying ggplot2 theme parameters. Users can easily customize color and theme settings before using the reset of NEST packages to ensure consistent settings in both static and interactive output at the downstream.

Nonnegative matrix factorization (NMF) is a technique to factorize a matrix with nonnegative values into the product of two matrices. Covariates are also allowed. Parallel computing is an option to enhance the speed and high-dimensional and large scale (and/or sparse) data are allowed. Relevant papers include: Wang Y. X. and Zhang Y. J. (2012). Nonnegative matrix factorization: A comprehensive review. IEEE Transactions on Knowledge and Data Engineering, 25(6), 1336-1353 <doi:10.1109/TKDE.2012.51> and Kim H. and Park H. (2008). Nonnegative matrix factorization based on alternating nonnegativity constrained least squares and active set method. SIAM Journal on Matrix Analysis and Applications, 30(2), 713-730 <doi:10.1137/07069239X>.

Social network analysis has become an essential tool in the study of complex systems. NetExplorer allows to visualize and explore complex systems. It is based on d3js library that brings 1) Graphical user interface; 2) Circular, linear, multilayer and force Layout; 3) Network live exploration and 4) SVG exportation.

Conduct a noncompartmental analysis with industrial strength. Some features are 1) Use of CDISC SDTM terms 2) Automatic or manual slope selection 3) Supporting both linear-up linear-down and linear-up log-down method 4) Interval(partial) AUCs with linear or log interpolation method * Reference: Gabrielsson J, Weiner D. Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications. 5th ed. 2016. (ISBN:9198299107).

This package provides customized forest plots for network meta-analysis incorporating direct, indirect, and NMA effects. Includes visualizations of evidence contributions through proportion bars based on the hat matrix and evidence flow decomposition.

Library to plot performance profiles (Dolan and More (2002) <doi:10.1007/s101070100263>) and nested performance profiles (Hekmati and Mirhajianmoghadam (2019) <doi:10.19139/soic-2310-5070-679>) for a given data frame.

This package provides residuals and overdispersion metrics to assess the fit of N-mixture models obtained using the package unmarked'. Details on the methods are given in Knape et al. (2017) <doi:10.1101/194340>.

Network changepoint analysis for undirected network data. The package implements a hidden Markov network change point model (Park and Sohn (2020)). Functions for break number detection using the approximate marginal likelihood and WAIC are also provided. This version includes performance optimizations with vectorized MCMC operations and modern ggplot2-based visualizations with colorblind-friendly palettes.

Apply neutrosophic regression type estimator and performs neutrosophic interval analysis including metric calculations for survey data.

Piecewise constant hazard functions are used to flexibly model survival distributions with non-proportional hazards and to simulate data from the specified distributions. A function to calculate weighted log-rank tests for the comparison of two hazard functions is included. Also, a function to calculate a test using the maximum of a set of test statistics from weighted log-rank tests (MaxCombo test) is provided. This test utilizes the asymptotic multivariate normal joint distribution of the separate test statistics. The correlation is estimated from the data. These methods are described in Ristl et al. (2021) <doi:10.1002/pst.2062>. Finally, a function is provided for the estimation and inferential statistics of various parameters that quantify the difference between two survival curves. Eligible parameters are differences in survival probabilities, log survival probabilities, complementary log log (cloglog) transformed survival probabilities, quantiles of the survival functions, log transformed quantiles, restricted mean survival times, as well as an average hazard ratio, the Cox model score statistic (logrank statistic), and the Cox-model hazard ratio. Adjustments for multiple testing and simultaneous confidence intervals are calculated using a multivariate normal approximation to the set of selected parameters.

Constructs (non)additive genetic relationship matrices, and their inverses, from a pedigree to be used in linear mixed effect models (A.K.A. the animal model'). Also includes other functions to facilitate the use of animal models. Some functions have been created to be used in conjunction with the R package asreml for the ASReml software, which can be obtained upon purchase from VSN international (<https://vsni.co.uk/software/asreml>).

Estimates and plots (as a single plot and as a heat map) the rolling window correlation coefficients between two time series and computes their statistical significance, which is carried out through a non-parametric computing-intensive method. This method addresses the effects due to the multiple testing (inflation of the Type I error) when the statistical significance is estimated for the rolling window correlation coefficients. The method is based on Monte Carlo simulations by permuting one of the variables (e.g., the dependent) under analysis and keeping fixed the other variable (e.g., the independent). We improve the computational efficiency of this method to reduce the computation time through parallel computing. The NonParRolCor package also provides examples with synthetic and real-life environmental time series to exemplify its use. Methods derived from R. Telford (2013) <https://quantpalaeo.wordpress.com/2013/01/04/> and J.M. Polanco-Martinez and J.L. Lopez-Martinez (2021) <doi:10.1016/j.ecoinf.2021.101379>.

Posterior sampling in several commonly used distributions using normalized power prior as described in Duan, Ye and Smith (2006) <doi:10.1002/env.752> and Ibrahim et.al. (2015) <doi:10.1002/sim.6728>. Sampling of the power parameter is achieved via either independence Metropolis-Hastings or random walk Metropolis-Hastings based on transformation.

Fits Bayesian regularized varying coefficient models with the Nonparametric Varying Coefficient Spike-and-Slab Lasso (NVC-SSL) introduced by Bai et al. (2023) <https://jmlr.org/papers/volume24/20-1437/20-1437.pdf>. Functions to fit frequentist penalized varying coefficients are also provided, with the option of employing the group lasso penalty of Yuan and Lin (2006) <doi:10.1111/j.1467-9868.2005.00532.x>, the group minimax concave penalty (MCP) of Breheny and Huang <doi:10.1007/s11222-013-9424-2>, or the group smoothly clipped absolute deviation (SCAD) penalty of Breheny and Huang (2015) <doi:10.1007/s11222-013-9424-2>.

This package provides functions to compute the non-negative garrote estimator as proposed by Breiman (1995) <https://www.jstor.org/stable/1269730> with the penalized initial estimators extension as proposed by Yuan and Lin (2007) <https://www.jstor.org/stable/4623260>.

Updating the now 10-year-old nycflights13 data package. It contains information about all flights that departed from the three main New York City airports in 2023 and metadata on airlines, airports, weather, and planes.

Enable programmatic interaction with Notion pages, databases, blocks, comments, and users through the Notion API <https://developers.notion.com/>. Provides both synchronous and asynchronous client interfaces for building workflows and automations that integrate with Notion workspaces. Supports all Notion API endpoints including content creation, data retrieval, and workspace management.

The noweb system for source code, implemented in R.

The Needleman-Wunsch global alignment algorithm can be used to find approximate matches between sample names in different data sets. See Wang et al. (2010) <doi:10.4137/CIN.S5613>.

Next-Generation Clustered Heat Maps (NG-CHMs) allow for dynamic exploration of heat map data in a web browser. NGCHM allows users to create both stand-alone HTML files containing a Next-Generation Clustered Heat Map, and .ngchm files to view in the NG-CHM viewer. See Ryan MC, Stucky M, et al (2020) <doi:10.12688/f1000research.20590.2> for more details.