Performing drug response analyses and IC50 estimations using n-Parameter logistic regression. Can also be applied to proliferation analyses.

Factorize binary matrices into rank-k components using the logistic function in the updating process. See e.g. Tomé et al (2015) <doi:10.1007/s11045-013-0240-9> .

Measure the dependence structure between two random variables with a new correlation coefficient and extend it to hypothesis test, feature screening and false discovery rate control.

Count the occurrence of sequences of values in a vector that meets certain conditions of length and magnitude. The method is based on the Run Length Encoding algorithm, available with base R, inspired by A. H. Robinson and C. Cherry (1967) <doi:10.1109/PROC.1967.5493>.

Simplify the exploratory data analysis process for multiple network data sets with the help of hierarchical clustering, consensus clustering and heatmaps. Multiple network data consists of multiple disjoint networks that have common variables (e.g. ego networks). This package contains the necessary tools for exploring such data, from the data pre-processing stage to the creation of dynamic visualizations.

This package provides functions for nominal data mining based on bipartite graphs, which build a pipeline for analysis and missing values imputation. Methods are mainly from the paper: Jafari, Mohieddin, et al. (2021) <doi:10.1101/2021.03.18.436040>, some new ones are also included.

Access the New Zealand Freshwater Fish Database from R and a few functions to clean the data once in R.

This package provides efficient methods to compute co-occurrence matrices, pointwise mutual information (PMI) and singular value decomposition (SVD). In the biomedical and clinical settings, one challenge is the huge size of databases, e.g. when analyzing data of millions of patients over tens of years. To address this, this package provides functions to efficiently compute monthly co-occurrence matrices, which is the computational bottleneck of the analysis, by using the RcppAlgos package and sparse matrices. Furthermore, the functions can be called on SQL databases, enabling the computation of co-occurrence matrices of tens of gigabytes of data, representing millions of patients over tens of years. Partly based on Hong C. (2021) <doi:10.1038/s41746-021-00519-z>.

National Statistical Office of Mongolia (NSO) is the national statistical service and an organization of Mongolian government. NSO provides open access to official data via its API <http://opendata.1212.mn/en/doc>. The package NSO1212 has functions for accessing the API service. The functions are compatible with the API v2.0 and get data sets and its detailed informations from the API.

R interface for the netstat command line utility used to retrieve and parse commonly used network statistics, including available and in-use transmission control protocol (TCP) ports. Primers offering technical background information on the netstat command line utility are available in the "Linux System Administrator's Manual" by Michael Kerrisk (2014) <https://man7.org/linux/man-pages/man8/netstat.8.html>, and on the Microsoft website (2017) <https://docs.microsoft.com/en-us/windows-server/administration/windows-commands/netstat>.

Apply neutrosophic regression type estimator and performs neutrosophic interval analysis including metric calculations for survey data.

This package provides methods for obtaining improved estimates of non-linear cross-validated risks are obtained using targeted minimum loss-based estimation, estimating equations, and one-step estimation (Benkeser, Petersen, van der Laan (2019), <doi:10.1080/01621459.2019.1668794>). Cross-validated area under the receiver operating characteristics curve (LeDell, Petersen, van der Laan (2015), <doi:10.1214/15-EJS1035>) and other metrics are included.

The noweb system for source code, implemented in R.

This package provides a graph visualization engine that emphasizes on aesthetics at the same time providing default parameters that yield out-of-the-box-nice visualizations. The package is built on top of The Grid Graphics Package and seamlessly work with igraph and network objects.

Computes the nonlinear cointegrating autoregressive distributed lag model with automatic bases aic and bic lags selection of independent variables proposed by (Shin, Yu & Greenwood-Nimmo, 2014 <doi:10.1007/978-1-4899-8008-3_9>).

Includes five particle filtering algorithms for use with state space models in the nimble system: Auxiliary', Bootstrap', Ensemble Kalman filter', Iterated Filtering 2', and Liu-West', as described in Michaud et al. (2021), <doi:10.18637/jss.v100.i03>. A full User Manual is available at <https://r-nimble.org>.

This package provides a model library for nlmixr2'. The models include (and plan to include) pharmacokinetic, pharmacodynamic, and disease models used in pharmacometrics. Where applicable, references for each model are included in the meta-data for each individual model. The package also includes model composition and modification functions to make model updates easier.

Create and manipulate numeric list ('nlist') objects. An nlist is an S3 list of uniquely named numeric objects. An numeric object is an integer or double vector, matrix or array. An nlists object is a S3 class list of nlist objects with the same names, dimensionalities and typeofs. Numeric list objects are of interest because they are the raw data inputs for analytic engines such as JAGS', STAN and TMB'. Numeric lists objects, which are useful for storing multiple realizations of of simulated data sets, can be converted to coda::mcmc and coda::mcmc.list objects.

Palettes generated from NBA jersey colorways.

To add the table of numbers at risk below the Kaplan-Meier plot.

Several tools for assessing the quality of fit of a gaussian nonlinear model are provided.

In shotgun proteomics, shared peptides (i.e., peptides that might originate from different proteins sharing homology, from different proteoforms due to alternative mRNA splicing, post-translational modifications, proteolytic cleavages, and/or allelic variants) represent a major source of ambiguity in protein identifications. The net4pg package allows to assess and handle ambiguity of protein identifications. It implements methods for two main applications. First, it allows to represent and quantify ambiguity of protein identifications by means of graph connected components (CCs). In graph theory, CCs are defined as the largest subgraphs in which any two vertices are connected to each other by a path and not connected to any other of the vertices in the supergraph. Here, proteins sharing one or more peptides are thus gathered in the same CC (multi-protein CC), while unambiguous protein identifications constitute CCs with a single protein vertex (single-protein CCs). Therefore, the proportion of single-protein CCs and the size of multi-protein CCs can be used to measure the level of ambiguity of protein identifications. The package implements a strategy to efficiently calculate graph connected components on large datasets and allows to visually inspect them. Secondly, the net4pg package allows to exploit the increasing availability of matched transcriptomic and proteomic datasets to reduce ambiguity of protein identifications. More precisely, it implement a transcriptome-based filtering strategy fundamentally consisting in the removal of those proteins whose corresponding transcript is not expressed in the sample-matched transcriptome. The underlying assumption is that, according to the central dogma of biology, there can be no proteins without the corresponding transcript. Most importantly, the package allows to visually inspect the effect of the filtering on protein identifications and quantify ambiguity before and after filtering by means of graph connected components. As such, it constitutes a reproducible and transparent method to exploit transcriptome information to enhance protein identifications. All methods implemented in the net4pg package are fully described in Fancello and Burger (2022) <doi:10.1186/s13059-022-02701-2>.

Due to Rstudio's status as open source software, we believe it will be utilized frequently for future data analysis by users whom lack formal training or experience with R'. The NMVANOVA (Novice Model Variation ANOVA) a streamlined variation of experimental design functions that allows novice Rstudio users to perform different model variations one-way analysis of variance without downloading multiple libraries or packages. Users can easily manipulate the data block, and needed inputs so that users only have to plugin the four designed variables/values.

Build and run spatially explicit agent-based models using only the R platform. NetLogoR follows the same framework as the NetLogo software (Wilensky (1999) <https://www.netlogo.org>) and is a translation in R of the structure and functions of NetLogo'. NetLogoR provides new R classes to define model agents and functions to implement spatially explicit agent-based models in the R environment. This package allows benefiting of the fast and easy coding phase from the highly developed NetLogo framework, coupled with the versatility, power and massive resources of the R software. Examples of two models from the NetLogo software repository (Ants <https://ccl.northwestern.edu/netlogo/models/Ants>) and Wolf-Sheep-Predation (<https://ccl.northwestern.edu/netlogo/models/WolfSheepPredation>), and a third, Butterfly, from Railsback and Grimm (2012) <https://www.railsback-grimm-abm-book.com/>, all written using NetLogoR are available. The NetLogo code of the original version of these models is provided alongside. A programming guide inspired from the NetLogo Programming Guide (<https://docs.netlogo.org/programming.html>) and a dictionary of NetLogo primitives (<https://docs.netlogo.org/dictionary.html>) equivalences are also available. NOTE: To increment time', these functions can use a for loop or can be integrated with a discrete event simulator, such as SpaDES (<https://cran.r-project.org/package=SpaDES>).