This package contains methods described by Dennis Helsel in his book "Statistics for Censored Environmental Data using Minitab and R" (2011) and courses and videos at <https://practicalstats.com>. This package incorporates functions of NADA and adds new functionality.

Nonparametric smoothing methods for density and regression estimation and inference with circular data. The package provides kernel density estimation along with inferential tools such as circular SiZer for feature significance, mode estimation, and modal clustering. It includes multiple methods for selecting the smoothing parameter, allowing users to optimize the trade-off between bias and variance. Various plotting functions help visualize estimated densities, modes, clusters, and significance features. For regression, the package implements nonparametric estimation of the mean regression function as well as other conditional characteristics, including modal regression and generalized regression. Bandwidth selection is also supported in the regression context, and testing procedures are available to assess structural features or effects in circular regression models.

This package provides Scilab n1qn1'. This takes more memory than traditional L-BFGS. The n1qn1 routine is useful since it allows prespecification of a Hessian. If the Hessian is near enough the truth in optimization it can speed up the optimization problem. The algorithm is described in the Scilab optimization documentation located at <https://www.scilab.org/sites/default/files/optimization_in_scilab.pdf>. This version uses manually modified code from f2c to make this a C only binary.

This package performs nonlinear Invariant Causal Prediction to estimate the causal parents of a given target variable from data collected in different experimental or environmental conditions, extending Invariant Causal Prediction from Peters, Buehlmann and Meinshausen (2016), <arXiv:1501.01332>, to nonlinear settings. For more details, see C. Heinze-Deml, J. Peters and N. Meinshausen: Invariant Causal Prediction for Nonlinear Models', <arXiv:1706.08576>.

Estimation of relatively complex nonlinear mixed-effects models, including the Sigmoidal Mixed Model and the Piecewise Linear Mixed Model with abrupt or smooth transition, through a single intuitive line of code and with automated generation of starting values.

Novel responsive tools for developing R based Shiny dashboards and applications. The scripts and style sheets are based on jQuery <https://jquery.com/> and Bootstrap <https://getbootstrap.com/>.

Palettes generated from NBA jersey colorways.

This package provides functions for adaptive parallel tempering (APT) with NIMBLE models. Adapted from Lacki & Miasojedow (2016) <DOI:10.1007/s11222-015-9579-0> and Miasojedow, Moulines and Vihola (2013) <DOI:10.1080/10618600.2013.778779>.

Represent network or igraph objects whose vertices can be represented by features in an sf object as a network graph surmising a sf plot. Fits into ggplot2 grammar.

Package including an interactive Shiny application for testing normality visually.

This package implements various simple function utilities and flexible pipelines to generate circular images for visualizing complex genomic and network data analysis features.

Sends queries to a specified Neo4J graph database, capturing results in a dataframe where appropriate. Other useful functions for the importing and management of data on the Neo4J server and basic local server admin.

Calculate the precision in mean differences (raw or Cohen's D) and correlation coefficients for different sample sizes. Uses permutations of the collected functional magnetic resonance imaging (fMRI) region of interest data. Method described in Klapwijk, Jongerling, Hoijtink and Crone (2024) <doi:10.31234/osf.io/cz32t>.

Noninferiority tests for difference in failure rates at a prespecified control rate or prespecified time. For details, see Fay and Follmann, 2016 <DOI:10.1177/1740774516654861>.

This data package contains the Item Response Theory (IRT) parameters for the National Center for Education Statistics (NCES) items used on the National Assessment of Education Progress (NAEP) from 1990 to 2015. The values in these tables are used along with NAEP data to turn student item responses into scores and include information about item difficulty, discrimination, and guessing parameter for 3 parameter logit (3PL) items. Parameters for Generalized Partial Credit Model (GPCM) items are also included. The adjustments table contains the information regarding the treatment of items (e.g., deletion of an item or a collapsing of response categories), when these items did not appear to fit the item response models used to describe the NAEP data. Transformation constants change the score estimates that are obtained from the IRT scaling program to the NAEP reporting metric. Values from the years 2000 - 2013 were taken from the NCES website <https://nces.ed.gov/nationsreportcard/> and values from 1990 - 1998 and 2015 were extracted from their NAEP data files. All subtest names were reduced and homogenized to one word (e.g. "Reading to gain information" became "information"). The various subtest names for univariate transformation constants were all homogenized to "univariate".

This package implements calculation of probability density function, cumulative distribution function, equicoordinate quantile function and survival function, and random numbers generation for the following multivariate distributions: Lomax (Pareto Type II), generalized Lomax, Mardiaâ s Pareto of Type I, Logistic, Burr, Cook-Johnsonâ s uniform, F and Inverted Beta. See Tapan Nayak (1987) <doi:10.2307/3214068>.

This package provides functions to fit linear mixed models based on convolutions of the generalized Laplace (GL) distribution. The GL mixed-effects model includes four special cases with normal random effects and normal errors (NN), normal random effects and Laplace errors (NL), Laplace random effects and normal errors (LN), and Laplace random effects and Laplace errors (LL). The methods are described in Geraci and Farcomeni (2020, Statistical Methods in Medical Research) <doi:10.1177/0962280220903763>.

NONMEM has been a tool for running nonlinear mixed effects models since the 80s and is still used today (Bauer 2019 <doi:10.1002/psp4.12404>). This tool allows you to convert NONMEM models to rxode2 (Wang, Hallow and James (2016) <doi:10.1002/psp4.12052>) and with simple models nlmixr2 syntax (Fidler et al (2019) <doi:10.1002/psp4.12445>). The nlmixr2 syntax requires the residual specification to be included and it is not always translated. If available, the rxode2 model will read in the NONMEM data and compare the simulation for the population model ('PRED') individual model ('IPRED') and residual model ('IWRES') to immediately show how well the translation is performing. This saves the model development time for people who are creating an rxode2 model manually. Additionally, this package reads in all the information to allow simulation with uncertainty (that is the number of observations, the number of subjects, and the covariance matrix) with a rxode2 model. This is complementary to the babelmixr2 package that translates nlmixr2 models to NONMEM and can convert the objects converted from nonmem2rx to a full nlmixr2 fit.

Color palettes based on nature inspired colours in "Sri Lanka".

Perform non-bipartite matching and matched randomization. A "bipartite" matching utilizes two separate groups, e.g. smokers being matched to nonsmokers or cases being matched to controls. A "non-bipartite" matching creates mates from one big group, e.g. 100 hospitals being randomized for a two-arm cluster randomized trial or 5000 children who have been exposed to various levels of secondhand smoke and are being paired to form a greater exposure vs. lesser exposure comparison. At the core of a non-bipartite matching is a N x N distance matrix for N potential mates. The distance between two units expresses a measure of similarity or quality as mates (the lower the better). The gendistance() and distancematrix() functions assist in creating this. The nonbimatch() function creates the matching that minimizes the total sum of distances between mates; hence, it is referred to as an "optimal" matching. The assign.grp() function aids in performing a matched randomization. Note bipartite matching can be performed using the prevent option in gendistance()'.

This package contains functions useful for debugging, set operations on vectors, and UTC date and time functionality. It adds a few vector manipulation verbs to purrr and dplyr packages. It can also generate an R file to install and update packages to simplify deployment into production. The functions were developed at the data science firm Numeract LLC and are used in several packages and projects.

Nonparametric test of independence between a pair of spatial objects (random fields, point processes) based on random shifts with torus or variance correction. See MrkviÄ ka et al. (2021) <doi:10.1016/j.spasta.2020.100430>, DvoŠák et al. (2022) <doi:10.1111/insr.12503>, DvoŠák and MrkviÄ ka (2024) <doi:10.1080/10618600.2024.2357626>.

The National Ecological Observatory Network (NEON) provides access to its numerous data products through its REST API, <https://data.neonscience.org/data-api/>. This package provides a high-level user interface for downloading and storing NEON data products. Unlike neonUtilities', this package will avoid repeated downloading, provides persistent storage, and improves performance. neonstore can also construct a local duckdb database of stacked tables, making it possible to work with tables that are far to big to fit into memory.

Set of functions to estimate kidney function and other traits of interest in nephrology.