This package implements regression models for binary data on the absolute risk scale. These models are applicable to cohort and population-based case-control data.

The Bayesian optimal interval (BOIN) design is a novel phase I clinical trial design for finding the maximum tolerated dose (MTD). It can be used to design both single-agent and drug-combination trials. The BOIN design is motivated by the top priority and concern of clinicians when testing a new drug, which is to effectively treat patients and minimize the chance of exposing them to subtherapeutic or overly toxic doses. The prominent advantage of the BOIN design is that it achieves simplicity and superior performance at the same time. The BOIN design is algorithm-based and can be implemented in a simple way similar to the traditional 3+3 design. The BOIN design yields an average performance that is comparable to that of the continual reassessment method (CRM, one of the best model-based designs) in terms of selecting the MTD, but has a substantially lower risk of assigning patients to subtherapeutic or overly toxic doses. For tutorial, please check Yan et al. (2020) <doi:10.18637/jss.v094.i13>.

This package implements several spatial and spatio-temporal scalable disease mapping models for high-dimensional count data using the INLA technique for approximate Bayesian inference in latent Gaussian models (Orozco-Acosta et al., 2021 <doi:10.1016/j.spasta.2021.100496>; Orozco-Acosta et al., 2023 <doi:10.1016/j.cmpb.2023.107403> and Vicente et al., 2023 <doi:10.1007/s11222-023-10263-x>). The creation and develpment of this package has been supported by Project MTM2017-82553-R (AEI/FEDER, UE) and Project PID2020-113125RB-I00/MCIN/AEI/10.13039/501100011033. It has also been partially funded by the Public University of Navarra (project PJUPNA2001).

Building on the docking layout manager provided by dockViewR', this provides a flexible front-end to blockr.core'. It provides an extension mechanism which allows for providing means to manipulate a board object via panel-based user interface components.

This package provides probability computation, data generation, and model estimation for fully-visible Boltzmann machines. It follows the methods described in Nguyen and Wood (2016a) <doi:10.1162/NECO_a_00813> and Nguyen and Wood (2016b) <doi:10.1109/TNNLS.2015.2425898>.

This package implements the methodological developments found in Hermes, van Heerwaarden, and Behrouzi (2024) <doi:10.48550/arXiv.2408.10558>, and allows for the statistical modeling of multi-attribute pairwise comparison data.

This package provides a modular framework for standardized analysis of thermal imaging data in animal experimentation. The package integrates thermographic data import (FLIR, raw, CSV), automated region of interest (ROI) segmentation based on EBImage (Pau et al., 2010 <doi:10.1093/bioinformatics/btq046>), interactive ROI refinement, and high-throughput batch processing.

Fast, dependency free, and vectorized base32 encoding and decoding. b32 supports the Crockford, Z, RFC 4648 lower, hex, and lower hex alphabets.

This package provides tools for constructing board/grid based games, as well as readily available game(s) for your entertainment.

Collection of tools to make R more convenient. Includes tools to summarize data using statistics not available with base R and manipulate objects for analyses.

Bayesian Mixture Survival Models using Additive Mixture-of-Weibull Hazards, with Lasso Shrinkage and Stratification. As a Bayesian dynamic survival model, it relaxes the proportional-hazard assumption. Lasso shrinkage controls overfitting, given the increase in the number of free parameters in the model due to presence of two Weibull components in the hazard function.

Bayesian estimation and variable selection for quantile regression models.

This package implements the distance measure for mixed-scale variables proposed by Buttler and Fickel (1995), based on normalized mean pairwise distances (Gini mean difference), and an R2 statistic to assess clustering quality.

Bayes screening and model discrimination follow-up designs.

This package provides tools for Bayesian basket trial design and analysis using a novel three-component local power prior framework with global borrowing control, pairwise similarity assessment and a borrowing threshold. Supports simulation-based evaluation of operating characteristics and comparison with other methods. Applicable to both equal and unequal sample size settings in early-phase oncology trials. For more details see Zhou et al. (2023) <doi:10.48550/arXiv.2312.15352>.

This package provides a collection of S4 classes, methods and functions to create and visualize business plans. Different types of cash flows can be defined, which can then be used and tabulated to create profit and loss statements, cash flow plans, investment and depreciation schedules, loan amortization schedules, etc. The methods are designed to produce handsome tables in both PDF and HTML using RMarkdown or Shiny'.

Transforms focal observations data, where different types of social interactions can be recorded by multiple observers, into asymmetric data matrices. Each cell in these matrices provides counts on the number of times a specific type of social interaction was initiated by the row subject and directed to the column subject.

When samples contain missing data, are small, or are suspected of bias, estimation of scale reliability may not be trustworthy. A recommended solution for this common problem has been Bayesian model estimation. Bayesian methods rely on user specified information from historical data or researcher intuition to more accurately estimate the parameters. This package provides a user friendly interface for estimating test reliability. Here, reliability is modeled as a beta distributed random variable with shape parameters alpha=true score variance and beta=error variance (Tanzer & Harlow, 2020) <doi:10.1080/00273171.2020.1854082>.

Waffle plots are rectangular pie charts that represent a quantity or abundances using colored squares or other symbol. This makes them better at transmitting information as the discrete number of squares is easier to read than the circular area of pie charts. While the original waffle charts were rectangular with 10 rows and columns, with a single square representing 1%, they are nowadays popular in various infographics to visualize any proportional ratios.

Build and use B-splines for interpolation and regression. In case of regression, equality constraints as well as monotonicity and/or positivity of B-spline weights can be imposed. Moreover, knot positions can be on regular grid or be part of optimized parameters too (in addition to the spline weights). For this end, bspline is able to calculate Jacobian of basis vectors as function of knot positions. User is provided with functions calculating spline values at arbitrary points. These functions can be differentiated and integrated to obtain B-splines calculating derivatives/integrals at any point. B-splines of this package can simultaneously operate on a series of curves sharing the same set of knots. bspline is written with concern about computing performance that's why the basis and Jacobian calculation is implemented in C++. The rest is implemented in R but without notable impact on computing speed.

Included here are babel routines for identifying unusual ribosome protected fragment counts given mRNA counts.

This package provides a continuous date scale, omitting weekends and holidays.

Efficient Markov Chain Monte Carlo (MCMC) algorithms for the fully Bayesian estimation of vectorautoregressions (VARs) featuring stochastic volatility (SV). Implements state-of-the-art shrinkage priors following Gruber & Kastner (2025) <doi:10.1016/j.ijforecast.2025.02.001>. Efficient equation-per-equation estimation following Kastner & Huber (2020) <doi:10.1002/for.2680> and Carrerio et al. (2021) <doi:10.1016/j.jeconom.2021.11.010>.

This package provides a practical tool for estimating the burden of common communicable diseases in settlements of displaced populations. An online version of the tool can be found at <http://who-refugee-bod.ecdf.ed.ac.uk/shiny/app/>. Estimates of burden of disease aim to synthesize data about cause-specific morbidity and mortality through a systematic approach that enables evidence-based decisions and comparisons across settings. The focus of this tool is on four acute communicable diseases and syndromes, including Acute respiratory infections, Acute diarrheal diseases, Acute jaundice syndrome and Acute febrile illnesses.