The field of immunology benefits from software that can predict which peptide sequences trigger an immune response. NetMHCIIpan is a such a tool: it predicts the binding strength of a short peptide to a Major Histocompatibility Complex class II (MHC-II) molecule. NetMHCIIpan can be used from a web server at <https://services.healthtech.dtu.dk/services/NetMHCIIpan-3.2/> or from the command-line, using a local installation. This package allows to call NetMHCIIpan from R.

Estimate the non-linear odds ratio and plot it against a continuous exposure.

This package provides a set of convenience functions as well as geographical/political data about Nigeria, aimed at simplifying work with data and information that are specific to the country.

Density, distribution function, quantile function and random generation for the Nakagami distribution of Nakagami (1960) <doi:10.1016/B978-0-08-009306-2.50005-4>.

These routines create multiple imputations of missing at random categorical data, and create multiply imputed synthesis of categorical data, with or without structural zeros. Imputations and syntheses are based on Dirichlet process mixtures of multinomial distributions, which is a non-parametric Bayesian modeling approach that allows for flexible joint modeling, described in Manrique-Vallier and Reiter (2014) <doi:10.1080/10618600.2013.844700>.

This package provides methods to estimate finite-population parameters under nonresponse that is not missing at random (NMAR, nonignorable). Incorporates auxiliary information and user-specified response models, and supports independent samples and complex survey designs via objects from the survey package. Provides diagnostics and optional variance estimates. For methodological background see Qin, Leung and Shao (2002) <doi:10.1198/016214502753479338> and Riddles, Kim and Im (2016) <doi:10.1093/jssam/smv047>.

This package provides a reproducible workflow for binning and visualizing NMR (nuclear magnetic resonance) spectra from environmental samples. The nmrrr package is intended for post-processing of NMR data, including importing, merging and, cleaning data from multiple files, visualizing NMR spectra, performing binning/integrations for compound classes, and relative abundance calculations. This package can be easily inserted into existing analysis workflows by users to help with analyzing and interpreting NMR data.

Exploration and analysis of compositional data in the framework of Aitchison (1986, ISBN: 978-94-010-8324-9). This package provides tools for chemical fingerprinting and source tracking of ancient materials.

Calculating the net reclassification improvement (NRI) for risk prediction models with time to event and binary data.

Utility to retrieve data from the National Health and Nutrition Examination Survey (NHANES) website <https://www.cdc.gov/nchs/nhanes/>.

Digital map data of Japan for choropleth mapping, including a circle cartogram.

Calculate Overall Survival or Recurrence-Free Survival for breast cancer patients, using NHS Predict'. The time interval for the estimation can be set up to 15 years, with default at 10. Incremental therapy benefits are estimated for hormone therapy, chemotherapy, trastuzumab, and bisphosphonates. An additional function, suited for SCAN audits, features a more user-friendly version of the code, with fewer inputs, but necessitates the correct standardised inputs. This work is not affiliated with the development of NHS Predict and its underlying statistical model. Details on NHS Predict can be found at: <doi:10.1186/bcr2464>. The web version of NHS Predict': <https://breast.predict.nhs.uk/>. A small dataset of 50 fictional patient observations is provided for the purpose of running examples with the main two functions, and an additional dataset is provided for running example with the dedicated SCAN function.

This package provides a novel integral estimator for estimating the causal effects with continuous treatments (or dose-response curves) and a localized derivative estimator for estimating the derivative effects. The inference on the dose-response curve and its derivative is conducted via nonparametric bootstrap. The reference paper is Zhang, Chen, and Giessing (2024) <doi:10.48550/arXiv.2405.09003>.

This package implements spatial null models and coordinate-space transformations for statistical comparison of brain maps, following the framework described in Markello et al. (2022) <doi:10.1038/s41592-022-01625-w>. Provides variogram-matching surrogates (Burt et al. 2020), Moran spectral randomization (Wagner & Dray 2015), and spin-based permutation tests (Alexander-Bloch et al. 2018). Includes an R interface to the neuromaps annotation registry for browsing, downloading, and comparing brain map annotations from the Open Science Framework ('OSF'). Integrates with ciftiTools for coordinate-space transforms.

This package provides a collection of data structures that represent volumetric brain imaging data. The focus is on basic data handling for 3D and 4D neuroimaging data. In addition, there are function to read and write NIFTI files and limited support for reading AFNI files.

An application for the empirical extrapolation of time features selecting and summarizing the most relevant patterns in time sequences.

Efficient tools for preparation, checking and post-processing of data in PK/PD (pharmacokinetics/pharmacodynamics) modeling, with focus on use of Nonmem, including consistency, traceability, and Nonmem compatibility of Data. Rigorously checks final Nonmem datasets. Implemented in data.table', but easily integrated with base and tidyverse'.

This package performs nonparametric estimation in mixture cure models, and significance tests for the cure probability. For details, see López-Cheda et al. (2017a) <doi:10.1016/j.csda.2016.08.002> and López-Cheda et al. (2017b) <doi:10.1007/s11749-016-0515-1>.

Acquires and synthesizes soil carbon fluxes at sites located in the National Ecological Observatory Network (NEON). Provides flux estimates and associated uncertainty as well as key environmental measurements (soil water, temperature, CO2 concentration) that are used to compute soil fluxes.

Addressing crucial research questions often necessitates a small sample size due to factors such as distinctive target populations, rarity of the event under study, time and cost constraints, ethical concerns, or group-level unit of analysis. Many readily available analytic methods, however, do not accommodate small sample sizes, and the choice of the best method can be unclear. The npboottprm package enables the execution of nonparametric bootstrap tests with pooled resampling to help fill this gap. Grounded in the statistical methods for small sample size studies detailed in Dwivedi, Mallawaarachchi, and Alvarado (2017) <doi:10.1002/sim.7263>, the package facilitates a range of statistical tests, encompassing independent t-tests, paired t-tests, and one-way Analysis of Variance (ANOVA) F-tests. The nonparboot() function undertakes essential computations, yielding detailed outputs which include test statistics, effect sizes, confidence intervals, and bootstrap distributions. Further, npboottprm incorporates an interactive shiny web application, nonparboot_app(), offering intuitive, user-friendly data exploration.

An interactive presentation on the topic of normal distribution using rmarkdown and shiny packages. It is helpful to those who want to learn normal distribution quickly and get a hands on experience. The presentation has a template for solving problems on normal distribution. Runtime examples are provided in the package function as well as at <https://kartikeyastat.shinyapps.io/NormalDistribution/>.

Analysis functions to quantify inputs importance in neural network models. Functions are available for calculating and plotting the inputs importance and obtaining the activation function of each neuron layer and its derivatives. The importance of a given input is defined as the distribution of the derivatives of the output with respect to that input in each training data point <doi:10.18637/jss.v102.i07>.

Interface to NatureServe (<https://www.natureserve.org/>). Includes methods to get data, image metadata, search taxonomic names, and make maps.

This package provides efficient implementation of the Narrowest-Over-Threshold methodology for detecting an unknown number of change-points occurring at unknown locations in one-dimensional data following deterministic signal + noise model. Currently implemented scenarios are: piecewise-constant signal, piecewise-constant signal with a heavy-tailed noise, piecewise-linear signal, piecewise-quadratic signal, piecewise-constant signal and with piecewise-constant variance of the noise. For details, see Baranowski, Chen and Fryzlewicz (2019) <doi:10.1111/rssb.12322>.