This package provides a data set package with the "Orsi" and "Park/Durand" fronts as SpatialLinesDataFrame objects. The Orsi et al. (1995) fronts are published at the Southern Ocean Atlas Database Page, and the Park et al. (2019) fronts are published at the SEANOE Altimetry-derived Antarctic Circumpolar Current fronts page, please see package CITATION for details.

Import data from Our World in Data', an organisation which publishes research and data on global economic and social issues.

Creativity research involves the need to score open-ended problems. Usually done by humans, automatic scoring using AI becomes more and more accurate. This package provides a simple interface to the Open Scoring API <https://openscoring.du.edu/docs>, leading creativity scoring technology by Organiscak et al. (2023) <doi:10.1016/j.tsc.2023.101356>. With it, you can score your own data directly from an R script.

This package provides functions to estimate the optimal threshold of diagnostic markers or treatment selection markers. The optimal threshold is the marker value that maximizes the utility of the marker based-strategy (for diagnostic or treatment selection) in a given population. The utility function depends on the type of marker (diagnostic or treatment selection), but always takes into account the preferences of the patients or the physician in the decision process. For estimating the optimal threshold, ones must specify the distributions of the marker in different groups (defined according to the type of marker, diagnostic or treatment selection) and provides data to estimate the parameters of these distributions. Ones must also provide some features of the target populations (disease prevalence or treatment efficacies) as well as the preferences of patients or physicians. The functions rely on Bayesian inference which helps producing several indicators derived from the optimal threshold. See Blangero, Y, Rabilloud, M, Ecochard, R, and Subtil, F (2019) <doi:10.1177/0962280218821394> for the original article that describes the estimation method for treatment selection markers and Subtil, F, and Rabilloud, M (2019) <doi:10.1002/bimj.200900242> for diagnostic markers.

Allows access to a proof-of-concept database containing Open Access species range models and relevant metadata. Access to the database is via both PostgreSQL connection and API <https://github.com/EnquistLab/Biendata-Frontend>, allowing diverse use-cases.

Fits ordinal regression models with elastic net penalty. Supported model families include cumulative probability, stopping ratio, continuation ratio, and adjacent category. These families are a subset of vector glm's which belong to a model class we call the elementwise link multinomial-ordinal (ELMO) class. Each family in this class links a vector of covariates to a vector of class probabilities. Each of these families has a parallel form, which is appropriate for ordinal response data, as well as a nonparallel form that is appropriate for an unordered categorical response, or as a more flexible model for ordinal data. The parallel model has a single set of coefficients, whereas the nonparallel model has a set of coefficients for each response category except the baseline category. It is also possible to fit a model with both parallel and nonparallel terms, which we call the semi-parallel model. The semi-parallel model has the flexibility of the nonparallel model, but the elastic net penalty shrinks it toward the parallel model. For details, refer to Wurm, Hanlon, and Rathouz (2021) <doi:10.18637/jss.v099.i06>.

An RStudio addin to assist with removing objects from the global environment. Features include removing objects according to name patterns and object type. During the course of an analysis, temporary objects are often created and this tool assists with removing them quickly. This can be useful when memory management within R is important.

It makes an objective Bayesian analysis of the spatial regression model using both the normal (NSR) and student-T (TSR) distributions. The functions provided give prior and posterior objective densities and allow default Bayesian estimation of the model regression parameters. Details can be found in Ordonez et al. (2020) <arXiv:2004.04341>.

Data input/output functions for data that conform to the Digital Imaging and Communications in Medicine (DICOM) standard, part of the Rigorous Analytics bundle.

Open the current working directory (or a given directory path) in your computer's file manager.

Growing collection of helper functions for point pattern analysis. Most functions are designed to work with the spatstat (<http://spatstat.org>) package. The focus of most functions are either null models or summary functions for spatial point patterns. For a detailed description of all null models and summary functions, see Wiegand and Moloney (2014, ISBN:9781420082548).

Efficient Monte Carlo Algorithms for the price and the sensitivities of Asian and European Options under Geometric Brownian Motion.

Tests the observed overlapping polygon area in a collection of polygons against a null model of random rotation, as explained in De la Cruz et al. (2017) <doi:10.13140/RG.2.2.12825.72801>.

This package provides a tool for visualizing numerical data (e.g., gene expression, protein abundance) on predefined anatomical maps of human/mouse organs and subcellular organelles. It supports customization of color schemes, filtering by organ systems (for organisms) or organelle types, and generation of optional bar charts for quantitative comparison. The package integrates coordinate data for organs and organelles to plot anatomical/subcellular contours, mapping data values to specific structures for intuitive visualization of biological data distribution.The underlying method was described in the preprint by Zhou et al. (2022) <doi:10.1101/2022.09.07.506938>.

DNA methylation is an important epigenetic process that regulates gene activity through chemical modifications of DNA without changing its sequence. OpEnCAST is a plant-specific ensemble-based prediction package that identifies 4mC, 5mC and 6mA methylation sites directly from DNA sequences. It combines multiple machine learning algorithms trained on monocot (Oryza sp.) and dicot (Arabidopsis sp.) reference models to deliver accurate predictions. This methodology is being inspired by the ensemble algorithm for methylation prediction developed by Wang et al. (2022) <doi:10.1186/s12859-022-04756-1>.

Convenient download functions enabling access Open Source Asset Pricing (OpenAP) data. This package enables users to download predictor portfolio returns (over 200 cross-sectional predictors with multiple portfolio construction methods) and firm characteristics (over 200 characteristics replicated from the academic asset pricing literature). Center for Research in Security Prices (CRSP)-based variables such as Price, Size, and Short-term Reversal can be downloaded with a Wharton Research Data Services (WRDS, <https://wrds-www.wharton.upenn.edu/>) subscription. For a full list of what is available, see <https://www.openassetpricing.com/>.

Overture Maps offers free and open geospatial map data sourced from various providers and standardized to a common schema. This tool allows you to download Overture Maps data for a specific region of interest and convert it to several different file formats. For more information, visit <https://overturemaps.org/download/>.

Inference using a class of Hidden Markov models (HMMs) called oHMMed'(ordered HMM with emission densities <doi:10.1186/s12859-024-05751-4>): The oHMMed algorithms identify the number of comparably homogeneous regions within observed sequences with autocorrelation patterns. These are modelled as discrete hidden states; the observed data points are then realisations of continuous probability distributions with state-specific means that enable ordering of these distributions. The observed sequence is labelled according to the hidden states, permitting only neighbouring states that are also neighbours within the ordering of their associated distributions. The parameters that characterise these state-specific distributions are then inferred. Relevant for application to genomic sequences, time series, or any other sequence data with serial autocorrelation.

Access data and processing functionalities of openEO compliant back-ends in R.

This package provides an end-to-end workflow for integrative analysis of two omics layers using sparse canonical correlation analysis (sCCA), including sample alignment, feature selection, network edge construction, and visualization of gene-metabolite relationships. The underlying methods are based on penalized matrix decomposition and sparse CCA (Witten, Tibshirani and Hastie (2009) <doi:10.1093/biostatistics/kxp008>), with design principles inspired by multivariate integrative frameworks such as mixOmics (Rohart et al. (2017) <doi:10.1371/journal.pcbi.1005752>).

Supports the modeling of ordinal random variables, like the outcomes of races, via Softmax regression, under the Harville <doi:10.1080/01621459.1973.10482425> and Henery <doi:10.1111/j.2517-6161.1981.tb01153.x> models.

Two-stage design for single-arm phase II trials with time-to-event endpoints (e.g., clinical trials on immunotherapies among cancer patients) can be calculated using this package. Two notable advantages of the package: 1) It provides flexible choices from three design methods (optimal, minmax, and admissible), and 2) the power of the design is more accurately calculated using the exact variance in the one-sample log-rank test. The package can be used for 1) planning the sample sizes and other design parameters, and 2) conducting the interim and final analyses for the Go/No-go decisions. More details about the design method can be found in: Wu, J, Chen L, Wei J, Weiss H, Chauhan A. (2020). <doi:10.1002/pst.1983>.

This package provides carefully chosen color palettes as used a.o. at OpenAnalytics <http://www.openanalytics.eu>.

This package provides a penalized regression framework that can simultaneously estimate the optimal treatment strategy and identify important variables. Appropriate for either censored or uncensored continuous response.