Defines thresholds for breaking data into a number of discrete levels, minimizing the (mean) squared error within all bins.

In the context of data fusion, the package provides a set of functions dedicated to the solving of recoding problems using optimal transportation theory (Gares, Guernec, Savy (2019) <doi:10.1515/ijb-2018-0106> and Gares, Omer (2020) <doi:10.1080/01621459.2020.1775615>). From two databases with no overlapping part except a subset of shared variables, the functions of the package assist users until obtaining a unique synthetic database, where the missing information is fully completed.

This package provides a derivative-based optimization framework that allows users to combine eight convergence criteria. Unlike standard optimization functions, this package includes a built-in mechanism to verify the positive definiteness of the Hessian matrix at the point of convergence. This additional check helps prevent the solver from falsely identifying non-optimal solutions, such as saddle points, as valid minima.

Image analysis techniques for positron emission tomography (PET) that form part of the Rigorous Analytics bundle.

This package provides an interface to OpenCL, allowing R to leverage computing power of GPUs and other HPC accelerator devices.

Allows distance based spatial clustering of georeferenced data by implementing the City Clustering Algorithm - CCA. Multiple versions allow clustering for a matrix, raster and single coordinates on a plain (Euclidean distance) or on a sphere (great-circle or orthodromic distance).

Calculate the optimal sample size allocation that uses the minimum resources to achieve targeted statistical power in experiments. Perform power analyses with and without accommodating costs and budget. The designs cover single-level and multilevel experiments detecting main, mediation, and moderation effects (and some combinations). The references for the proposed methods include: (1) Shen, Z., & Kelcey, B. (2020). Optimal sample allocation under unequal costs in cluster-randomized trials. Journal of Educational and Behavioral Statistics, 45(4): 446-474. <doi:10.3102/1076998620912418>. (2) Shen, Z., & Kelcey, B. (2022b). Optimal sample allocation for three-level multisite cluster-randomized trials. Journal of Research on Educational Effectiveness, 15 (1), 130-150. <doi:10.1080/19345747.2021.1953200>. (3) Shen, Z., & Kelcey, B. (2022a). Optimal sample allocation in multisite randomized trials. The Journal of Experimental Education, 90(3), 693-711. <doi:10.1080/00220973.2020.1830361>. (4) Shen, Z., Leite, W., Zhang, H., Quan, J., & Kuang, H. (2025). Using ant colony optimization to identify optimal sample allocations in cluster-randomized trials. The Journal of Experimental Education, 93(1), 167-185. <doi:10.1080/00220973.2024.2306392>. (5) Shen, Z., Li, W., & Leite, W. (in press). Statistical power and optimal design for randomized controlled trials investigating mediation effects. Psychological Methods. <doi:10.1037/met0000698>. (6) Champely, S. (2020). pwr: Basic functions for power analysis (Version 1.3-0) [Software]. Available from <https://CRAN.R-project.org/package=pwr>.

Creating maps for statistical analysis such as proportional circles, choropleth, typology and flows. Some functions use shiny or leaflet technologies for dynamism and interactivity. The great features are : - Create maps in a web environment where the parameters are modifiable on the fly ('shiny and leaflet technologies). - Create interactive maps through zoom and pop-up ('leaflet technology). - Create frozen maps with the possibility to add labels.

Picks the suitable cell types in spatial and scRNA-seq data using shrinkage methods. The package includes curated reference gene expression profiles for human and mouse cell types, facilitating immediate application to common spatial transcriptomics or scRNA datasets. Additionally, users can input custom reference data to support tissue- or experiment-specific analyses.

Provide methods for estimating optimal treatment regimes in survival contexts with Kaplan-Meier-like estimators when no unmeasured confounding assumption is satisfied (Jiang, R., Lu, W., Song, R., and Davidian, M. (2017) <doi:10.1111/rssb.12201>) and when no unmeasured confounding assumption fails to hold and a binary instrument is available (Xia, J., Zhan, Z., Zhang, J. (2022) <arXiv:2210.05538>).

This package provides the setup and calculations needed to run a likelihood-based continual reassessment method (CRM) dose finding trial and performs simulations to assess design performance under various scenarios. 3 dose finding designs are included in this package: ordinal proportional odds model (POM) CRM, ordinal continuation ratio (CR) model CRM, and the binary 2-parameter logistic model CRM. These functions allow customization of design characteristics to vary sample size, cohort sizes, target dose-limiting toxicity (DLT) rates, discrete or continuous dose levels, combining ordinal grades 0 and 1 into one category, and incorporate safety and/or stopping rules. For POM and CR model designs, ordinal toxicity grades are specified by common terminology criteria for adverse events (CTCAE) version 4.0. Function pseudodata creates the necessary starting models for these 3 designs, and function nextdose estimates the next dose to test in a cohort of patients for a target DLT rate. We also provide the function crmsimulations to assess the performance of these 3 dose finding designs under various scenarios.

Obtain optimum block from Non-overlapping Block Bootstrap method.

An unofficial wrapper for okx exchange v5 API <https://www.okx.com/docs-v5/en/>, including REST API and WebSocket API.

Objects and methods to handle and solve the min-sum location problem, also known as Fermat-Weber problem. The min-sum location problem search for a point such that the weighted sum of the distances to the demand points are minimized. See "The Fermat-Weber location problem revisited" by Brimberg, Mathematical Programming, 1, pg. 71-76, 1995. <DOI:10.1007/BF01592245>. General global optimization algorithms are used to solve the problem, along with the adhoc Weiszfeld method, see "Sur le point pour lequel la Somme des distances de n points donnes est minimum", by Weiszfeld, Tohoku Mathematical Journal, First Series, 43, pg. 355-386, 1937 or "On the point for which the sum of the distances to n given points is minimum", by E. Weiszfeld and F. Plastria, Annals of Operations Research, 167, pg. 7-41, 2009. <DOI:10.1007/s10479-008-0352-z>.

The supplied code allows for the generation of discrete time series of oscillating species. General shapes can be selected by means of individual functions, which are widely customizable by means of function arguments. All code was developed in the Biological Information Processing Group at the BioQuant Center at Heidelberg University, Germany.

This package provides methods for determining optimum plot size and shape in field experiments using Fairfield-Smith's variance law approach. It will evaluate field variability, determine optimum plot size and shape and study fertility trends across the field.

Data used in compiling the Handbook of UK Urban Tree Allometric Equations and Size Characteristics (Fennel 2024). The data include measurements of height, crown radius and diameter at breast height (DBH) for UK urban trees. For more details see Fennell (2024) Handbook of UK Urban Tree Allometric Equations and Size Characteristics (Version 1.4). <doi:10.13140/RG.2.2.28745.04961>.

Social media sites often embed cards when links are shared, based on metadata in the Open Graph Protocol (<https://ogp.me/>). This supports extracting that metadata from a website. It further allows for the creation of tags to add to a website to support the Open Graph Protocol and provides a list of the standard tags and their required properties.

This package implements the out-of-treatment testing from Kuelpmann and Kuzmics (2020) <doi:10.2139/ssrn.3441675> based on the Vuong Test introduced in Vuong (1989) <doi:10.2307/1912557>. Out-of treatment testing allows for a direct, pairwise likelihood comparison of theories, calibrated with pre-existing data.

This package provides functions for implementing different versions of the OSCV method in the kernel regression and density estimation frameworks. The package mainly supports the following articles: (1) Savchuk, O.Y., Hart, J.D. (2017). Fully robust one-sided cross-validation for regression functions. Computational Statistics, <doi:10.1007/s00180-017-0713-7> and (2) Savchuk, O.Y. (2017). One-sided cross-validation for nonsmooth density functions, <arXiv:1703.05157>.

This package provides tools for multivariate outlier detection based on geometric properties of multivariate data using random directional projections. Observation-level outlier scores are computed by jointly probing radial magnitude and angular alignment through repeated projections onto random directions, with optional robust centering and covariance adjustment. In addition to global outlier scoring, the method produces dimension-level contribution measures to support interpretation of detected anomalies. Visualization utilities are included to summarize directional contributions for extreme observations.

Estimation of value and hedging strategy of call and put options, based on optimal hedging and Monte Carlo method, from Chapter 3 of Statistical Methods for Financial Engineering', by Bruno Remillard, CRC Press, (2013).

It implements functions for simulation and estimation of the ordinal latent block model (OLBM), as described in Corneli, Bouveyron and Latouche (2019).

This package provides a system for calculating the minimum total sample size needed to achieve a prespecified power or the optimal allocation for each treatment group with a fixed total sample size to maximize the power.