Simplifies the creation of xlsx files by providing a high level interface to writing, styling and editing worksheets.

Implementation of a likelihood ratio test of differential onset of senescence between two groups. Given two groups with measures of age and of an individual trait likely to be subjected to senescence (e.g. body mass), OnAge provides an asymptotic p-value for the null hypothesis that senescence starts at the same age in both groups. The package implements the procedure used in Douhard et al. (2017) <doi:10.1111/oik.04421>.

Quaternions and Octonions are four- and eight- dimensional extensions of the complex numbers. They are normed division algebras over the real numbers and find applications in spatial rotations (quaternions), and string theory and relativity (octonions). The quaternions are noncommutative and the octonions nonassociative. See the package vignette for more details.

The Open Data Format (ODF) is a new, non-proprietary, multilingual, metadata enriched, and zip-compressed data format with metadata structured in the Data Documentation Initiative (DDI) Codebook standard. This package allows reading and writing of data files in the Open Data Format (ODF) in R, and displaying metadata in different languages. For further information on the Open Data Format, see <https://opendataformat.github.io/>.

This package provides a unified object-oriented framework for numerical optimizers in R. Allows for both minimization and maximization with any optimizer, optimization over more than one function argument, measuring of computation time, setting a time limit for long optimization tasks.

Estimates optimal classification (Poole 2000) <doi:10.1093/oxfordjournals.pan.a029814> scores from roll call votes supplied though a rollcall object from package pscl'.

This package provides a single function options.ifunset(...) is contained herewith, which allows the user to set a global option ONLY if it is not already set. By this token, for package maintainers this function can be used in preference to the standard options(...) function, making provision for THEIR end user to place options(...) directives within their .Rprofile file, which will not be overridden at the point when a package is loaded.

Calculate similarity between ontological terms and sets of ontological terms based on term information content and assess statistical significance of similarity in the context of a collection of terms sets - Greene et al. 2017 <doi:10.1093/bioinformatics/btw763>.

We proposes a framework that provides real time support for early detection of anomalous series within a large collection of streaming time series data. By definition, anomalies are rare in comparison to a system's typical behaviour. We define an anomaly as an observation that is very unlikely given the forecast distribution. The algorithm first forecasts a boundary for the system's typical behaviour using a representative sample of the typical behaviour of the system. An approach based on extreme value theory is used for this boundary prediction process. Then a sliding window is used to test for anomalous series within the newly arrived collection of series. Feature based representation of time series is used as the input to the model. To cope with concept drift, the forecast boundary for the system's typical behaviour is updated periodically. More details regarding the algorithm can be found in Talagala, P. D., Hyndman, R. J., Smith-Miles, K., et al. (2019) <doi:10.1080/10618600.2019.1617160>.

This package provides functionalities and data structures to retrieve, analyze and visualize aviation data. It includes a client interface to the OpenSky API <https://opensky-network.org>. It allows retrieval of flight information, as well as aircraft state vectors.

Offers a gene-based meta-analysis test with filtering to detect gene-environment interactions (GxE) with association data, proposed by Wang et al. (2018) <doi:10.1002/gepi.22115>. It first conducts a meta-filtering test to filter out unpromising SNPs by combining all samples in the consortia data. It then runs a test of omnibus-filtering-based GxE meta-analysis (ofGEM) that combines the strengths of the fixed- and random-effects meta-analysis with meta-filtering. It can also analyze data from multiple ethnic groups.

This package creates a client with queries for the UK Open Banking ('Open Data') API.

Computes A-, MV-, D- and E-optimal or near-optimal block designs for two-colour cDNA microarray experiments using the linear fixed effects and mixed effects models where the interest is in a comparison of all possible elementary treatment contrasts. The algorithms used in this package are based on the treatment exchange and array exchange algorithms of Debusho, Gemechu and Haines (2018) <doi:10.1080/03610918.2018.1429617>. The package also provides an optional method of using the graphical user interface (GUI) R package tcltk to ensure that it is user friendly.

This package implements the efficient algorithm by Ortmann and Brandes (2017) <doi:10.1007/s41109-017-0027-2> to compute the orbit-aware frequency distribution of induced and non-induced quads, i.e. subgraphs of size four. Given an edge matrix, data frame, or a graph object (e.g., igraph'), the orbit-aware counts are computed respective each of the edges and nodes.

An interface to easily run local language models with Ollama <https://ollama.com> server and API endpoints (see <https://github.com/ollama/ollama/blob/main/docs/api.md> for details). It lets you run open-source large language models locally on your machine.

Complete R implementation of the OpenAI Python SDK'. Provides full compatibility with the OpenAI API including chat completions, embeddings', images, audio, fine-tuning, and model management.

Convert odds ratio to relative risk in cohort studies with partial data information (Wang (2013) <doi:10.18637/jss.v055.i05>).

Access and Analyze Official Development Assistance (ODA) data using the OECD API <https://gitlab.algobank.oecd.org/public-documentation/dotstat-migration/-/raw/main/OECD_Data_API_documentation.pdf>. ODA data includes sovereign-level aid data such as key aggregates (DAC1), geographical distributions (DAC2A), project-level data (CRS), and multilateral contributions (Multisystem).

Provide methods for estimating optimal treatment regimes in survival contexts with Kaplan-Meier-like estimators when no unmeasured confounding assumption is satisfied (Jiang, R., Lu, W., Song, R., and Davidian, M. (2017) <doi:10.1111/rssb.12201>) and when no unmeasured confounding assumption fails to hold and a binary instrument is available (Xia, J., Zhan, Z., Zhang, J. (2022) <arXiv:2210.05538>).

This ONEST software implements the method of assessing the pathologist agreement in reading PD-L1 assays (Reisenbichler et al. (2020 <doi:10.1038/s41379-020-0544-x>)), to determine the minimum number of evaluators needed to estimate agreement involving a large number of raters. Input to the program should be binary(1/0) pathology data, where â 0â may stand for negative and â 1â for positive. Additional examples were given using the data from Rimm et al. (2017 <doi:10.1001/jamaoncol.2017.0013>).

Developed to help researchers who need to model the kinetics of carbon dioxide (CO2) production in alcoholic fermentation of wines, beers and other fermented products. The following models are available for modeling the carbon dioxide production curve as a function of time: 5PL, Gompertz and 4PL. This package has different functions, which applied can: perform the modeling of the data obtained in the fermentation and return the coefficients, analyze the model fit and return different statistical metrics, and calculate the kinetic parameters: Maximum production of carbon dioxide; Maximum rate of production of carbon dioxide; Moment in which maximum fermentation rate occurs; Duration of the latency phase for carbon dioxide production; Carbon dioxide produced until maximum fermentation rate occurs. In addition, a function that generates graphs with the observed and predicted data from the models, isolated and combined, is available. Gava, A., Borsato, D., & Ficagna, E. (2020)."Effect of mixture of fining agents on the fermentation kinetics of base wine for sparkling wine production: Use of methodology for modeling". <doi:10.1016/j.lwt.2020.109660>.

Trains per-horizon probabilistic ensembles from a univariate time series. It supports rpart', glmnet', and kNN engines with flexible residual distributions and heteroscedastic scale models, weighting variants by calibration-aware scores. A Gaussian/t copula couples the marginals to simulate joint forecast paths, returning quantiles, means, and step increments across horizons.

Utilizes the Black-Scholes-Merton option pricing model to calculate key option analytics and perform graphical analysis of various option strategies. Provides functions to calculate the option premium and option greeks of European-style options.

OpenTelemetry is a collection of tools, APIs', and SDKs used to instrument, generate, collect, and export telemetry data (metrics, logs, and traces) for analysis in order to understand your software's performance and behavior. This package contains the OpenTelemetry SDK', and exporters. Use this package to export traces, metrics, logs from instrumented R code. Use the otel package to instrument your R code for OpenTelemetry'.