Identify the optimal timing for new treatment initiation during multiple state disease transition, including multistate model fitting, simulation of mean residual lifetime for a given transition state, and estimation of confidence interval. The method is referred to de Wreede, L., Fiocco, M., & Putter, H. (2011) <doi:10.18637/jss.v038.i07>.

This package provides functions to access and download data from the Open Case Studies <https://www.opencasestudies.org/> repositories on GitHub <https://github.com/opencasestudies>. Different functions enable users to grab the data they need at different sections in the case study, as well as download the whole case study repository. All the user needs to do is input the name of the case study being worked on. The package relies on the httr::GET() function to access files through the GitHub API. The functions usethis::use_zip() and usethis::create_from_github() are used to clone and/or download the case study repositories. To cite an individual case study, please see the respective README file at <https://github.com/opencasestudies/>. <https://github.com/opencasestudies/ocs-bp-rural-and-urban-obesity> <https://github.com/opencasestudies/ocs-bp-air-pollution> <https://github.com/opencasestudies/ocs-bp-vaping-case-study> <https://github.com/opencasestudies/ocs-bp-opioid-rural-urban> <https://github.com/opencasestudies/ocs-bp-RTC-wrangling> <https://github.com/opencasestudies/ocs-bp-RTC-analysis> <https://github.com/opencasestudies/ocs-bp-youth-disconnection> <https://github.com/opencasestudies/ocs-bp-youth-mental-health> <https://github.com/opencasestudies/ocs-bp-school-shootings-dashboard> <https://github.com/opencasestudies/ocs-bp-co2-emissions> <https://github.com/opencasestudies/ocs-bp-diet>.

Calculate the optimal sample size allocation that uses the minimum resources to achieve targeted statistical power in experiments. Perform power analyses with and without accommodating costs and budget. The designs cover single-level and multilevel experiments detecting main, mediation, and moderation effects (and some combinations). The references for the proposed methods include: (1) Shen, Z., & Kelcey, B. (2020). Optimal sample allocation under unequal costs in cluster-randomized trials. Journal of Educational and Behavioral Statistics, 45(4): 446-474. <doi:10.3102/1076998620912418>. (2) Shen, Z., & Kelcey, B. (2022b). Optimal sample allocation for three-level multisite cluster-randomized trials. Journal of Research on Educational Effectiveness, 15 (1), 130-150. <doi:10.1080/19345747.2021.1953200>. (3) Shen, Z., & Kelcey, B. (2022a). Optimal sample allocation in multisite randomized trials. The Journal of Experimental Education, 90(3), 693-711. <doi:10.1080/00220973.2020.1830361>. (4) Shen, Z., Leite, W., Zhang, H., Quan, J., & Kuang, H. (2025). Using ant colony optimization to identify optimal sample allocations in cluster-randomized trials. The Journal of Experimental Education, 93(1), 167-185. <doi:10.1080/00220973.2024.2306392>. (5) Shen, Z., Li, W., & Leite, W. (in press). Statistical power and optimal design for randomized controlled trials investigating mediation effects. Psychological Methods. <doi:10.1037/met0000698>. (6) Champely, S. (2020). pwr: Basic functions for power analysis (Version 1.3-0) [Software]. Available from <https://CRAN.R-project.org/package=pwr>.

Representations, conversions and display of orientation SO(3) data. See the orientlib help topic for details.

This package provides a collection of functions to construct sets of orthogonal polynomials and their recurrence relations. Additional functions are provided to calculate the derivative, integral, value and roots of lists of polynomial objects.

Flexible optimizer with numerous input specifications for detailed parameterisation. Designed for complex loss functions with state and parameter space constraints. Visualization tools for validation and analysis of the convergence are included.

The online principal component method can process the online data set. The philosophy of the package is described in Guo G. (2018) <doi:10.1080/10485252.2018.1531130>.

Computes confidence regions on the location of response surface optima. Response surface models can be up to cubic polynomial models in up to 5 controllable factors, or Thin Plate Spline models in 2 controllable factors.

Trains per-horizon probabilistic ensembles from a univariate time series. It supports rpart', glmnet', and kNN engines with flexible residual distributions and heteroscedastic scale models, weighting variants by calibration-aware scores. A Gaussian/t copula couples the marginals to simulate joint forecast paths, returning quantiles, means, and step increments across horizons.

This package provides a comprehensive system for designing and implementing on-farm precision field agronomic trials. You provide field data, tell ofpetrial how to design a trial, and get readily-usable trial design files and a report checks the validity and reliability of the trial design.

This package provides a unified object-oriented framework for numerical optimizers in R. Allows for both minimization and maximization with any optimizer, optimization over more than one function argument, measuring of computation time, setting a time limit for long optimization tasks.

Allows performing forwards prediction for the General Unified Threshold model of Survival using compiled ode code. This package was created to avoid dependency with the morse package that requires the installation of JAGS'. This package is based on functions from the morse package v3.3.1: Virgile Baudrot, Sandrine Charles, Marie Laure Delignette-Muller, Wandrille Duchemin, Benoit Goussen, Nils Kehrein, Guillaume Kon-Kam-King, Christelle Lopes, Philippe Ruiz, Alexander Singer and Philippe Veber (2021) <https://CRAN.R-project.org/package=morse>.

This package provides utilities for processing of Oxy-Bisulfite microarray data (e.g. via the Illumina Infinium platform, <http://www.illumina.com>) with tandem arrays, one using conventional bisulfite conversion, the other using oxy-bisulfite conversion.

This package provides functions for extracting text and tables from PDF-based order documents. It provides an n-gram-based approach for identifying the language of an order document. It furthermore uses R-package pdftools to extract the text from an order document. In the case that the PDF document is only including an image (because it is scanned document), R package tesseract is used for OCR. Furthermore, the package provides functionality for identifying and extracting order position tables in order documents based on a clustering approach.

This package provides access to selected functions and data available through any OpenBioMaps <https://openbiomaps.org> server instance. OpenBioMaps is an open-source biodiversity data management platform designed for conservation professionals and researchers. User authentication and access control are handled through OpenBioMaps login credentials.

This package provides a system for calculating the minimum total sample size needed to achieve a prespecified power or the optimal allocation for each treatment group with a fixed total sample size to maximize the power.

Implementation of the Open Perimetry Interface (OPI) for simulating and controlling visual field machines using R. The OPI is a standard for interfacing with visual field testing machines (perimeters) first started as an open source project with support of Haag-Streit in 2010. It specifies basic functions that allow many visual field tests to be constructed. As of February 2022 it is fully implemented on the Haag-Streit Octopus 900 and CrewT ImoVifa ('Topcon Tempo') with partial implementations on the Centervue Compass, Kowa AP 7000 and Android phones. It also has a cousin: the R package visualFields', which has tools for analysing and manipulating visual field data.

Estimate the positron emission tomography (PET) neuroreceptor occupancies from the total volumes of distribution of a set of regions of interest. Fitting methods include the simple reference region', ordinary least squares (sometimes known as occupancy plot), and restricted maximum likelihood estimation'.

An approach to outlier detection in RNA-seq and related data based on five statistics. OutSeekR implements an outlier test by comparing the distributions of these statistics in observed data with those of simulated null data.

This package provides a function to detect and trim outliers in Gaussian mixture model-based clustering using methods described in Clark and McNicholas (2024) <doi:10.1007/s00357-024-09473-3>.

This package performs the O2PLS data integration method for two datasets, yielding joint and data-specific parts for each dataset. The algorithm automatically switches to a memory-efficient approach to fit O2PLS to high dimensional data. It provides a rigorous and a faster alternative cross-validation method to select the number of components, as well as functions to report proportions of explained variation and to construct plots of the results. See the software article by el Bouhaddani et al (2018) <doi:10.1186/s12859-018-2371-3>, and Trygg and Wold (2003) <doi:10.1002/cem.775>. It also performs Sparse Group (Penalized) O2PLS, see Gu et al (2020) <doi:10.1186/s12859-021-03958-3> and cross-validation for the degree of sparsity.

Allows you to easily execute expensive compute operations only once, and save the resulting object to disk.

An interface to the search API of HAL <https://hal.science/>, the French open archive for scholarly documents from all academic fields. This package provides programmatic access to the API <https://api.archives-ouvertes.fr/docs> and allows to search for records and download documents.

In the context of data fusion, the package provides a set of functions dedicated to the solving of recoding problems using optimal transportation theory (Gares, Guernec, Savy (2019) <doi:10.1515/ijb-2018-0106> and Gares, Omer (2020) <doi:10.1080/01621459.2020.1775615>). From two databases with no overlapping part except a subset of shared variables, the functions of the package assist users until obtaining a unique synthetic database, where the missing information is fully completed.