Bayesian dynamic borrowing is an approach to incorporating external data to supplement a randomized, controlled trial analysis in which external data are incorporated in a dynamic way (e.g., based on similarity of outcomes); see Viele 2013 <doi:10.1002/pst.1589> for an overview. This package implements the hierarchical commensurate prior approach to dynamic borrowing as described in Hobbes 2011 <doi:10.1111/j.1541-0420.2011.01564.x>. There are three main functionalities. First, psborrow2 provides a user-friendly interface for applying dynamic borrowing on the study results handles the Markov Chain Monte Carlo sampling on behalf of the user. Second, psborrow2 provides a simulation framework to compare different borrowing parameters (e.g. full borrowing, no borrowing, dynamic borrowing) and other trial and borrowing characteristics (e.g. sample size, covariates) in a unified way. Third, psborrow2 provides a set of functions to generate data for simulation studies, and also allows the user to specify their own data generation process. This package is designed to use the sampling functions from cmdstanr which can be installed from <https://stan-dev.r-universe.dev>.

This package contains sixteen moisture sorption isotherm models, which evaluate the fitness of adsorption and desorption curves for further understanding of the relationship between moisture content and water activity. Fitness evaluation is conducted through parameter estimation and error analysis. Moreover, graphical representation, hysteresis area estimation, and isotherm classification through the equation of Blahovec & Yanniotis (2009) <doi:10.1016/j.jfoodeng.2008.08.007> which is based on the classification system introduced by Brunauer et. al. (1940) <doi:10.1021/ja01864a025> are also included for the visualization of models and hysteresis.

When using pooled p-values to adjust for multiple testing, there is an inherent balance that must be struck between rejection based on weak evidence spread among many tests and strong evidence in a few, explored in Salahub and Olford (2023) <arXiv:2310.16600>. This package provides functionality to compute marginal and central rejection levels and the centrality quotient for p-value pooling functions and provides implementations of the chi-squared quantile pooled p-value (described in Salahub and Oldford (2023)) and a proposal from Heard and Rubin-Delanchy (2018) <doi:10.1093/biomet/asx076> to control the quotient's value.

All PubChem compounds are downloaded to a local computer, but for each compound, only partial records are used. The data are organized into small files referenced by PubChem CID. This package also contains functions to parse the biologically relevant compounds from all PubChem compounds, using biological database sources, pathway presence, and taxonomic relationships. Taxonomy is used to generate a lowest common ancestor taxonomy ID (NCBI) for each biological metabolite, which then enables creation of taxonomically specific metabolome databases for any taxon.

Data from All the World's Primates relational SQL database and other tabular datasets are made available via drivers and connection functions. Additionally we provide several functions and examples to facilitate the merging and aggregation of these tabular inputs.

This package provides functions to create high-quality, publication-ready plots for numeric and categorical data, including bar plots, violin plots, boxplots, line plots, error bars, correlation plots, linear model plots, odds ratio plots, and normality plots.

Quantification of variation in organismal color patterns as obtained from image data. Patternize defines homology between pattern positions across images either through fixed landmarks or image registration. Pattern identification is performed by categorizing the distribution of colors using RGB thresholds or image segmentation.

This package provides tools to compute unbiased pleiotropic heritability estimates of complex diseases from genome-wide association studies (GWAS) summary statistics. We estimate pleiotropic heritability from GWAS summary statistics by estimating the proportion of variance explained from an estimated genetic correlation matrix (Bulik-Sullivan et al. 2015 <doi:10.1038/ng.3406>) and employing a Monte-Carlo bias correction procedure to account for sampling noise in genetic correlation estimates.

This package provides a method for fitting the entire regularization path of the principal components lasso for linear and logistic regression models. The algorithm uses cyclic coordinate descent in a path-wise fashion. See URL below for more information on the algorithm. See Tay, K., Friedman, J. ,Tibshirani, R., (2014) Principal component-guided sparse regression <arXiv:1810.04651>.

This package provides a set of raw datasets used to create SDTM domains in pharmaversesdtm package.

Plot malaria parasite genetic data on two or more episodes. Compute per-person posterior probabilities that each Plasmodium vivax (Pv) recurrence is a recrudescence, relapse, or reinfection (3Rs) using per-person P. vivax genetic data on two or more episodes and a statistical model described in Taylor, Foo and White (2022) <doi:10.1101/2022.11.23.22282669>. Plot per-recurrence posterior probabilities.

Check if a remote computer is up. It can either just call the system ping command, or check a specified TCP port.

Automated identification of printed array positions from high content microscopy images and the export of those positions as individual images written to output as multi-layered tiff files.

Allows users to derive multi-objective weights from pairwise comparisons, which research shows is more repeatable, transparent, and intuitive other techniques. These weights can be rank existing alternatives or to define a multi-objective utility function for optimization.

This package provides a set of Analysis Data Model (ADaM) datasets constructed by modifying the ADaM datasets in the pharmaverseadam package to meet J&J Innovative Medicine's standard data structure for Clinical and Statistical Programming.

Test-based Image structural similarity measure and test of independence. This package implements the key functions of two tasks: (1) computing image structural similarity measure PSSIM of Wang, Maldonado and Silwal (2011) <DOI:10.1016/j.csda.2011.04.021>; and (2) test of independence between a response and a covariate in presence of heteroscedastic treatment effects proposed by Wang, Tolos, and Wang (2010) <DOI:10.1002/cjs.10068>.

This package provides functions to estimate the size-controlled phenotypic integration index, a novel method by Torices & Méndez (2014) <doi:10.1086/676622> to solve problems due to individual size when estimating integration (namely, larger individuals have larger components, which will drive a correlation between components only due to resource availability that might obscure the observed measures of integration). In addition, the package also provides the classical estimation by Wagner (1984) <doi:10.1007/BF00275224>, bootstrapping and jackknife methods to calculate confidence intervals and a significance test for both integration indices. Further details can be found in Torices & Muñoz-Pajares <doi:10.3732/apps.1400104>.

This package implements IV-estimator and Bayesian estimator for linear-in-means Spatial Autoregressive (SAR) model (see LeSage, 1997 <doi:10.1177/016001769702000107>; Lee, 2004 <doi:10.1111/j.1468-0262.2004.00558.x>; Bramoullé et al., 2009 <doi:10.1016/j.jeconom.2008.12.021>), while assuming that only a partial information about the network structure is available. Examples are when the adjacency matrix is not fully observed or when only consistent estimation of the network formation model is available (see Boucher and Houndetoungan, 2025 <doi:10.48550/arXiv.2509.08145>).

Useful git hooks for R building on top of the multi-language framework pre-commit for hook management. This package provides git hooks for common tasks like formatting files with styler or spell checking as well as wrapper functions to access the pre-commit executable.

This package provides the tools needed to benchmark the R2 value corresponding to a certain acceptable noise level while also providing a rescaling function based on that noise level yielding a new value of R2 we refer to as R2k which is independent of both the number of degrees of freedom and the noise distribution function.

Use Pokemon(R) inspired palettes with additional ggplot2 scales. Palettes are the colours in each Pokemon's sprite, ordered by how common they are in the image. The first 386 Pokemon are currently provided.

Prism <https://prismjs.com/> is a lightweight, extensible syntax highlighter, built with modern web standards in mind. This package provides server-side rendering in R using V8 such that no JavaScript library is required in the resulting HTML documents. Over 400 languages are supported.

This package provides a function for estimating the transition probabilities in an illness-death model. The transition probabilities can be estimated from the unsmoothed landmark estimators developed by de Una-Alvarez and Meira-Machado (2015) <doi:10.1111/biom.12288>. Presmoothed estimates can also be obtained through the use of a parametric family of binary regression curves, such as logit, probit or cauchit. The additive logistic regression model and nonparametric regression are also alternatives which have been implemented. The idea behind the presmoothed landmark estimators is to use the presmoothing techniques developed by Cao et al. (2005) <doi:10.1007/s00180-007-0076-6> in the landmark estimation of the transition probabilities.

Perform inference in the secondary analysis setting with linked data potentially containing mismatch errors. Only the linked data file may be accessible and information about the record linkage process may be limited or unavailable. Implements the General Framework for Regression with Mismatched Data developed by Slawski et al. (2023) <doi:10.48550/arXiv.2306.00909>. The framework uses a mixture model for pairs of linked records whose two components reflect distributions conditional on match status, i.e., correct match or mismatch. Inference is based on composite likelihood and the Expectation-Maximization (EM) algorithm. The package currently supports Cox Proportional Hazards Regression (right-censored data only) and Generalized Linear Regression Models (Gaussian, Gamma, Poisson, and Logistic (binary models only)). Information about the underlying record linkage process can be incorporated into the method if available (e.g., assumed overall mismatch rate, safe matches, predictors of match status, or predicted probabilities of correct matches).