Picks the suitable cell types in spatial and scRNA-seq data using shrinkage methods. The package includes curated reference gene expression profiles for human and mouse cell types, facilitating immediate application to common spatial transcriptomics or scRNA datasets. Additionally, users can input custom reference data to support tissue- or experiment-specific analyses.

This package provides functionality to construct standardised tables from health care data formatted according to the Observational Medical Outcomes Partnership (OMOP) Common Data Model. The package includes tools to build key tables such as observation period and drug era, among others.

Optimal testing under general dependence. The R package implements procedures proposed in Wang, Han, and Tong (2022). The package includes parameter estimation procedures, the computation for the posterior probabilities, and the testing procedure.

An assortment of helper functions for managing data (e.g., rotating values in matrices by a user-defined angle, switching from row- to column-indexing), dates (e.g., intuiting year from messy date strings), handling missing values (e.g., removing elements/rows across multiple vectors or matrices if any have an NA), text (e.g., flushing reports to the console in real-time); and combining data frames with different schema (copying, filling, or concatenating columns or applying functions before combining).

An implementation of the Ordered Forest estimator as developed in Lechner & Okasa (2019) <arXiv:1907.02436>. The Ordered Forest flexibly estimates the conditional probabilities of models with ordered categorical outcomes (so-called ordered choice models). Additionally to common machine learning algorithms the orf package provides functions for estimating marginal effects as well as statistical inference thereof and thus provides similar output as in standard econometric models for ordered choice. The core forest algorithm relies on the fast C++ forest implementation from the ranger package (Wright & Ziegler, 2017) <arXiv:1508.04409>.

This package provides a mutable Signal object can report changes to its state, clients could register functions so that they are called whenever the signal is emitted. The signal could be emitted, disconnected, blocked, unblocked, and buffered.

Search and extract data from the Organization for Economic Cooperation and Development (OECD).

Use health data in the Observational Medical Outcomes Partnership Common Data Model format in Spark'. Functionality includes creating all required tables and fields and creation of a single reference to the data. Native Spark functionality is supported.

This package provides programmatic access to the Open Experience Sampling Method ('openESM') database (<https://openesmdata.org>), a collection of harmonized experience sampling datasets. The package enables researchers to discover, download, and work with the datasets while ensuring proper citation and license compliance.

Obtain optimum block from Non-overlapping Block Bootstrap method.

Ordination comprises several multivariate exploratory and explanatory techniques with theoretical foundations in geometric data analysis; see Podani (2000, ISBN:90-5782-067-6) for techniques and applications and Le Roux & Rouanet (2005) <doi:10.1007/1-4020-2236-0> for foundations. Greenacre (2010, ISBN:978-84-923846) shows how the most established of these, including principal components analysis, correspondence analysis, multidimensional scaling, factor analysis, and discriminant analysis, rely on eigen-decompositions or singular value decompositions of pre-processed numeric matrix data. These decompositions give rise to a set of shared coordinates along which the row and column elements can be measured. The overlay of their scatterplots on these axes, introduced by Gabriel (1971) <doi:10.1093/biomet/58.3.453>, is called a biplot. ordr provides inspection, extraction, manipulation, and visualization tools for several popular ordination classes supported by a set of recovery methods. It is inspired by and designed to integrate into Tidyverse workflows provided by Wickham et al (2019) <doi:10.21105/joss.01686>.

Developed to help researchers who need to model the kinetics of carbon dioxide (CO2) production in alcoholic fermentation of wines, beers and other fermented products. The following models are available for modeling the carbon dioxide production curve as a function of time: 5PL, Gompertz and 4PL. This package has different functions, which applied can: perform the modeling of the data obtained in the fermentation and return the coefficients, analyze the model fit and return different statistical metrics, and calculate the kinetic parameters: Maximum production of carbon dioxide; Maximum rate of production of carbon dioxide; Moment in which maximum fermentation rate occurs; Duration of the latency phase for carbon dioxide production; Carbon dioxide produced until maximum fermentation rate occurs. In addition, a function that generates graphs with the observed and predicted data from the models, isolated and combined, is available. Gava, A., Borsato, D., & Ficagna, E. (2020)."Effect of mixture of fining agents on the fermentation kinetics of base wine for sparkling wine production: Use of methodology for modeling". <doi:10.1016/j.lwt.2020.109660>.

This package provides a model-agnostic framework for selecting dataset-specific imputation methods for missing values in numerical data related to pain. Lotsch J, Ultsch A (2025) "A model-agnostic framework for dataset-specific selection of missing value imputation methods in pain-related numerical data" Canadian Journal of Pain (in minor revision).

Density, distribution function, quantile function and random generation for the Odd Log-Logistic Generalized Gamma proposed in Prataviera, F. et al (2017) <doi:10.1080/00949655.2016.1238088>.

Package for estimating the parameters of a nonlinear function using iterated linearization via Taylor series. Method is based on KubÃ¡Ä ek (2000) ISBN: 80-244-0093-6. The algorithm is a generalization of the procedure given in Köning, R., Wimmer, G. and Witkovský, V. (2014) <doi:10.1088/0957-0233/25/11/115001>.

This package performs the O2PLS data integration method for two datasets, yielding joint and data-specific parts for each dataset. The algorithm automatically switches to a memory-efficient approach to fit O2PLS to high dimensional data. It provides a rigorous and a faster alternative cross-validation method to select the number of components, as well as functions to report proportions of explained variation and to construct plots of the results. See the software article by el Bouhaddani et al (2018) <doi:10.1186/s12859-018-2371-3>, and Trygg and Wold (2003) <doi:10.1002/cem.775>. It also performs Sparse Group (Penalized) O2PLS, see Gu et al (2020) <doi:10.1186/s12859-021-03958-3> and cross-validation for the degree of sparsity.

This package provides access to selected functions and data available through any OpenBioMaps <https://openbiomaps.org> server instance. OpenBioMaps is an open-source biodiversity data management platform designed for conservation professionals and researchers. User authentication and access control are handled through OpenBioMaps login credentials.

Utilizes the Black-Scholes-Merton option pricing model to calculate key option analytics and perform graphical analysis of various option strategies. Provides functions to calculate the option premium and option greeks of European-style options.

Computes profile extrema functions for arbitrary functions. If the function is expensive-to-evaluate it computes profile extrema by emulating the function with a Gaussian process (using package DiceKriging'). In this case uncertainty quantification on the profile extrema can also be computed. The different plotting functions for profile extrema give the user a tool to better locate excursion sets.

This package implements a general framework for creating dependency graphs using projection as introduced in Fan, Feng and Xia (2019)<arXiv:1501.01617>. Both lasso and sparse additive model projections are implemented. Both Pearson correlation and distance covariance options are available to generate the graph.

Fits Bayesian mixture models to estimate marker dosage for dominant markers in autopolyploids using JAGS (1.0 or greater) as outlined in Baker et al "Bayesian estimation of marker dosage in sugarcane and other autopolyploids" (2010, <doi:10.1007/s00122-010-1283-z>). May be used in conjunction with polySegratio for simulation studies and comparison with standard methods.

This package provides a secure and user-friendly interface to interact with the Plug <https://plugbytpf.com.br> API'. It enables developers to store and manage tokens securely using the keyring package, retrieve data from API endpoints with the httr2 package, and handle large datasets with chunked data fetching. Designed for simplicity and security, the package facilitates seamless integration with Plug ecosystem.

This function plots a contour line with a user-defined probability and tightness of fit.

This package provides functions for the computation of F-, f- and D-statistics (e.g., Fst, hierarchical F-statistics, Patterson's F2, F3, F3*, F4 and D parameters) in population genomics studies from allele count or Pool-Seq read count data and for the fitting, building and visualization of admixture graphs. The package also includes several utilities to manipulate Pool-Seq data stored in standard format (e.g., such as vcf files or rsync files generated by the the PoPoolation software) and perform conversion to alternative format (as used in the BayPass and SelEstim software). As of version 2.0, the package also includes utilities to manipulate standard allele count data (e.g., stored in TreeMix', BayPass and SelEstim format, see the Package vignette for details).