Fit flexible (excess) hazard regression models with the possibility of including non-proportional effects of covariables and of adding a random effect at the cluster level (corresponding to a shared frailty). A detailed description of the package functionalities is provided in Charvat and Belot (2021) <doi: 10.18637/jss.v098.i14>.

This package contains functions to access movement data stored in movebank.org as well as tools to visualize and statistically analyze animal movement data, among others functions to calculate dynamic Brownian Bridge Movement Models. Move helps addressing movement ecology questions.

Fast Bayesian probability estimation for multimodal categorical data using speed-optimized Markov chain Monte Carlo (MCMC) implementation (Metropolis-Hastings-within-partial-Gibbs). The package provides efficient algorithms for detecting subpopulations, estimating mixture components, and assigning observations to subgroups with probability estimates. The methods are described in Dioszegi, G. et al. (2026) "Automatic Bayesian Mixture Modeling for Multimodal Categorical Data via Integrated Mode Detection and Metropolis-Hastings-within-Gibbs Sampling" (submitted to Journal of Statistical Software).

This package implements a model-based clustering method for categorical life-course sequences relying on mixtures of exponential-distance models introduced by Murphy et al. (2021) <doi:10.1111/rssa.12712>. A range of flexible precision parameter settings corresponding to weighted generalisations of the Hamming distance metric are considered, along with the potential inclusion of a noise component. Gating covariates can be supplied in order to relate sequences to baseline characteristics and sampling weights are also accommodated. The models are fitted using the EM algorithm and tools for visualising the results are also provided.

This package implements a minimum-spanning-tree-based heuristic for k-means clustering using a union-find disjoint set and the algorithm in Kruskal (1956) <doi:10.1090/S0002-9939-1956-0078686-7>.

An implementation of Multi-Task Logistic Regression (MTLR) for R. This package is based on the method proposed by Yu et al. (2011) which utilized MTLR for generating individual survival curves by learning feature weights which vary across time. This model was further extended to account for left and interval censored data.

This package provides a mechanism to plot an interactive map using Mapbox GL (<https://docs.mapbox.com/mapbox-gl-js/api/>), a javascript library for interactive maps, and Deck.gl (<https://deck.gl/>), a javascript library which uses WebGL for visualising large data sets.

This package performs maximum likelihood estimation for finite mixture models for families including Normal, Weibull, Gamma and Lognormal by using EM algorithm, together with Newton-Raphson algorithm or bisection method when necessary. It also conducts mixture model selection by using information criteria or bootstrap likelihood ratio test. The data used for mixture model fitting can be raw data or binned data. The model fitting process is accelerated by using R package Rcpp'.

Calculates exact hypothesis tests to compare a treatment and a reference group with respect to multiple binary endpoints. The tested null hypothesis is an identical multidimensional distribution of successes and failures in both groups. The alternative hypothesis is a larger success proportion in the treatment group in at least one endpoint. The tests are based on the multivariate permutation distribution of subjects between the two groups. For this permutation distribution, rejection regions are calculated that satisfy one of different possible optimization criteria. In particular, regions with maximal exhaustion of the nominal significance level, maximal power under a specified alternative or maximal number of elements can be found. Optimization is achieved by a branch-and-bound algorithm. By application of the closed testing principle, the global hypothesis tests are extended to multiple testing procedures.

Many tools for making, manipulating, and modifying many different types of networks. All functions operate with matrices, edge lists, and igraph', network', and tidygraph objects, on directed, multiplex, multimodal, signed, and other networks. The package includes functions for importing and exporting, creating and generating networks, modifying networks and node and tie attributes, and describing networks with sensible defaults.

Provide a sample size calculator for micro-randomized trials (MRTs) based on methodology developed in Sample Size Calculations for Micro-randomized Trials in mHealth by Liao et al. (2016) <DOI:10.1002/sim.6847>.

This package provides an interface to the Maxar Geospatial Platform (MGP) Application Programming Interface. <https://www.maxar.com/maxar-geospatial-platform> It facilitates imagery searches using the MGP Streaming Application Programming Interface via the Web Feature Service (WFS) method, and supports image downloads through Web Map Service (WMS) and Web Map Tile Service (WMTS) Open Geospatial Consortium (OGC) methods. Additionally, it integrates with the Maxar Geospatial Platform Basemaps Application Programming Interface for accessing Maxar basemaps imagery and seamlines. The package also offers seamless integration with the Maxar Geospatial Platform Discovery Application Programming Interface, allowing users to search, filter, and sort Maxar content, while retrieving detailed metadata in formats like SpatioTemporal Asset Catalog (STAC) and GeoJSON.

This package provides functions of marginal mean and quantile regression models are used to analyze environmental exposure and biomonitoring data with repeated measurements and non-detects (i.e., values below the limit of detection (LOD)), as well as longitudinal exposure data that include non-detects and time-dependent covariates. For more details see Chen IC, Bertke SJ, Curwin BD (2021) <doi:10.1038/s41370-021-00345-1>, Chen IC, Bertke SJ, Estill CF (2024) <doi:10.1038/s41370-024-00640-7>, Chen IC, Bertke SJ, Dahm MM (2024) <doi:10.1093/annweh/wxae068>, and Chen IC (2025) <doi:10.1038/s41370-025-00752-8>.

This package provides functions that allow you to create your own color palette from an image, using mathematical algorithms.

Exploratory and predictive methods for the analysis of several blocks of variables measured on the same individuals.

This package provides functions to support data cleaning, evaluation, and description, developed for integration with Maelstrom Research software tools. madshapR provides functions primarily to evaluate and manipulate datasets and data dictionaries in preparation for data harmonization with the package Rmonize and to facilitate integration and transfer between RStudio servers and secure Opal environments. madshapR functions can be used independently but are optimized in conjunction with â Rmonizeâ functions for streamlined and coherent harmonization processing.

Conduct random forests-based meta-analysis, obtain partial dependence plots for metaforest and classic meta-analyses, and cross-validate and tune metaforest- and classic meta-analyses in conjunction with the caret package. A requirement of classic meta-analysis is that the studies being aggregated are conceptually similar, and ideally, close replications. However, in many fields, there is substantial heterogeneity between studies on the same topic. Classic meta-analysis lacks the power to assess more than a handful of univariate moderators. MetaForest, by contrast, has substantial power to explore heterogeneity in meta-analysis. It can identify important moderators from a larger set of potential candidates (Van Lissa, 2020). This is an appealing quality, because many meta-analyses have small sample sizes. Moreover, MetaForest yields a measure of variable importance which can be used to identify important moderators, and offers partial prediction plots to explore the shape of the marginal relationship between moderators and effect size.

This package provides functions to support compatibility between Maelstrom R packages and Opal environment. Opal is the OBiBa core database application for biobanks. It is used to build data repositories that integrates data collected from multiple sources. Opal Maelstrom is a specific implementation of this software. This Opal client is specifically designed to interact with Opal Maelstrom distributions to perform operations on the R server side. The user must have adequate credentials. Please see <https://opaldoc.obiba.org/> for complete documentation.

This package provides a forward simulator for generating synthetic metacommunity data. As an in silico experimental platform, it enables researchers to simulate community shifts, test theoretical frameworks, and benchmark analytical algorithms prior to empirical application. Key capabilities include mechanistic simulations driven by demography, dispersal, and interactions, GIS interoperability via the terra package for dynamic environments, and a virtual ecologist module that simulates imperfect detection and survey errors to mimic real-world biodiversity data.

Enables the creation of Moodle quiz questions using literate programming with R Markdown. This makes it easy to quickly create a quiz that can be randomly replicated with new datasets, questions, and options for answers.

Testing CRAN and Bioconductor mirror speed by recording download time of src/base/COPYING (for CRAN) and packages/release/bioc/html/ggtree.html (for Bioconductor).

Interactions between different biological entities are crucial for the function of biological systems. In such networks, nodes represent biological elements, such as genes, proteins and microbes, and their interactions can be defined by edges, which can be either binary or weighted. The dysregulation of these networks can be associated with different clinical conditions such as diseases and response to treatments. However, such variations often occur locally and do not concern the whole network. To capture local variations of such networks, we propose multiplex network differential analysis (MNDA). MNDA allows to quantify the variations in the local neighborhood of each node (e.g. gene) between the two given clinical states, and to test for statistical significance of such variation. Yousefi et al. (2023) <doi:10.1101/2023.01.22.525058>.

Extended tools for analyzing telemetry data using generalized hidden Markov models. Features of momentuHMM (pronounced ``momentum'') include data pre-processing and visualization, fitting HMMs to location and auxiliary biotelemetry or environmental data, biased and correlated random walk movement models, hierarchical HMMs, multiple imputation for incorporating location measurement error and missing data, user-specified design matrices and constraints for covariate modelling of parameters, random effects, decoding of the state process, visualization of fitted models, model checking and selection, and simulation. See McClintock and Michelot (2018) <doi:10.1111/2041-210X.12995>.

Fit finite mixture distribution models to grouped data and conditional data by maximum likelihood using a combination of a Newton-type algorithm and the EM algorithm.