Fits non-homogeneous Markov multistate models and misclassification-type hidden Markov models in continuous time to intermittently observed data. Implements the methods in Titman (2011) <doi:10.1111/j.1541-0420.2010.01550.x>. Uses direct numerical solution of the Kolmogorov forward equations to calculate the transition probabilities.

Fast functions implemented in C++ via Rcpp to support the NeuroAnatomy Toolbox ('nat') ecosystem. These functions provide large speed-ups for basic manipulation of neuronal skeletons over pure R functions found in the nat package. The expectation is that end users will not use this package directly, but instead the nat package will automatically use routines from this package when it is available to enable large performance gains.

These routines create multiple imputations of missing at random categorical data, and create multiply imputed synthesis of categorical data, with or without structural zeros. Imputations and syntheses are based on Dirichlet process mixtures of multinomial distributions, which is a non-parametric Bayesian modeling approach that allows for flexible joint modeling, described in Manrique-Vallier and Reiter (2014) <doi:10.1080/10618600.2013.844700>.

Visualization and analysis tools to aid in the interpretation of neural network models. Functions are available for plotting, quantifying variable importance, conducting a sensitivity analysis, and obtaining a simple list of model weights.

This package provides a unified, programmatic interface for searching, browsing, and retrieving metadata from various international organization data repositories that use the National Data Archive ('NADA') software, such as the World Bank, FAO', and the International Household Survey Network ('IHSN'). Functions allow users to discover available data collections, country codes, and access types, perform complex searches using keyword and spatial/temporal filters, and retrieve detailed study information, including file lists and variable-level data dictionaries. It simplifies access to microdata for researchers and policy analysts globally.

This package provides functions to produce advanced ascii graphics, directly to the terminal window. This package utilizes the txtplot() function from the txtplot package, to produce text-based histograms, empirical cumulative distribution function plots, scatterplots with fitted and regression lines, quantile plots, density plots, image plots, and contour plots.

This package performs network meta-analysis using integrated nested Laplace approximations ('INLA') which is described in Guenhan, Held, and Friede (2018) <doi:10.1002/jrsm.1285>. Includes methods to assess the heterogeneity and inconsistency in the network. Contains more than ten different network meta-analysis dataset. INLA package can be obtained from <https://www.r-inla.org>.

An interface to Neptune. A metadata store for MLOps, built for teams that run a lot of experiments. It gives you a single place to log, store, display, organize, compare, and query all your model-building metadata. Neptune is used for: â ¢ Experiment tracking: Log, display, organize, and compare ML experiments in a single place. â ¢ Model registry: Version, store, manage, and query trained models, and model building metadata. â ¢ Monitoring ML runs live: Record and monitor model training, evaluation, or production runs live For more information see <https://neptune.ai/>.

This package implements nonparametric multiple change-point detection for univariate sequences using Wild Binary Segmentation, as described in Ross (2026) "Nonparametric Detection of Multiple Location-Scale Change Points via Wild Binary Segmentation" <doi:10.48550/arXiv.2107.01742>. The package provides Mann--Whitney, Mood, Lepage, Cramér--von Mises, modified Baumgartner, standardised Zhang Z_C, and standardised Anderson--Darling rank-based statistics, together with method-specific thresholds for controlling the probability of incorrectly detecting a change point in a homogeneous sequence.

This package implements the non-asymptotically valid and asymptotically exact confidence intervals in two cases: estimation of the mean, and estimation of (a linear combination of) the coefficients in a linear regression model, following (Derumigny, Girard and Guyonvarch, 2025) <doi:10.48550/arXiv.2507.16776>.

Description: Provides methods for Neutrosophic Analysis of Variance (NANOVA) and Neutrosophic Analysis of Covariance (NANCOVA) for row-column designs, including Latin square designs and Youden square designs, using interval-valued observations. The package computes neutrosophic sums of squares, mean squares, interval-valued F-statistics, significance tests, and multiple comparisons using Least Significant Difference (LSD) procedures. For crisp data, users may enter identical lower and upper values of responses to obtain classical Analysis of Variance (ANOVA) results. Similarly, users may enter identical lower and upper values for both responses and covariates to obtain classical Analysis of Covariance (ANCOVA) results.

This package implements the nonparametric trend test for one or several samples as proposed by Bathke (2009) <doi:10.1007/s00184-008-0171-x>. The method provides a unified framework for analyzing trends in both independent and dependent data samples, making it a versatile tool for various study designs. The package allows for the evaluation of different trend alternatives, including two-sided (general trend), monotonic increasing, and monotonic decreasing trends. As a nonparametric procedure, it does not require the assumption of data normality, offering a robust alternative to parametric tests.

This package implements a method that builds the coefficients of a polynomial model that performs almost equivalently as a given neural network (densely connected). This is achieved using Taylor expansion at the activation functions. The obtained polynomial coefficients can be used to explain features (and their interactions) importance in the neural network, therefore working as a tool for interpretability or eXplainable Artificial Intelligence (XAI). See Morala et al. 2021 <doi:10.1016/j.neunet.2021.04.036>, and 2023 <doi:10.1109/TNNLS.2023.3330328>.

Cleans and Normalizes FLUOstar DBF and DAT Files obtained from liposome flux assays. Users should verify extended usage of the package on files from other assay types.

Supports staggered difference-in-differences designs with nonlinear outcomes for both panel and repeated cross-section data. Implements estimators for staggered treatment adoption with binary, count, and other nonlinear outcomes, extending Callaway and Sant'Anna (2021) <doi:10.1016/j.jeconom.2020.12.001> to settings with nonlinear outcome models such as logit, probit, and Poisson. For panel data, units are followed over time and idname identifies repeated observations. For repeated cross-section data, observations are independent within each time period; idname is optional and may identify survey records or households, but the estimator does not require the same units to appear across periods. Repeated cross-section estimation includes pooled quasi-maximum likelihood approaches motivated by Wooldridge (2023) <doi:10.1093/ectj/utad016>, with optional weighting and clustered inference. Methods also draw on Roth and Sant'Anna (2023) <doi:10.3982/ECTA19402> and Sant'Anna and Zhao (2020) <doi:10.1016/j.jeconom.2020.06.003>.

This package provides a set of techniques that can be used to develop, validate, and implement automated classifiers. A powerful tool for transforming raw data into meaningful information, ncodeR (Shaffer, D. W. (2017) Quantitative Ethnography. ISBN: 0578191687) is designed specifically for working with big data: large document collections, logfiles, and other text data.

An implementation of network-based statistics in R using mixed effects models. Theoretical background for Network-Based Statistics can be found in Zalesky et al. (2010) <doi:10.1016/j.neuroimage.2010.06.041>. For Mixed Effects Models check the R package <https://CRAN.R-project.org/package=nlme>.

This package provides tools for analyzing spatial data, especially non- Gaussian areal data. The current version supports the sparse restricted spatial regression model of Hughes and Haran (2013) <DOI:10.1111/j.1467-9868.2012.01041.x>, the centered autologistic model of Caragea and Kaiser (2009) <DOI:10.1198/jabes.2009.07032>, and the Bayesian spatial filtering model of Hughes (2017) <arXiv:1706.04651>.

Clinical reporting figures require to use consistent colors and configurations. As a part of the Roche open-source clinical reporting project, namely the NEST project, the nestcolor package specifies the color code and default theme with specifying ggplot2 theme parameters. Users can easily customize color and theme settings before using the reset of NEST packages to ensure consistent settings in both static and interactive output at the downstream.

Motivated by changing administrative boundaries over time, the nuts package can convert European regional data with NUTS codes between versions (2006, 2010, 2013, 2016 and 2021) and levels (NUTS 1, NUTS 2 and NUTS 3). The package uses spatial interpolation as in Lam (1983) <doi:10.1559/152304083783914958> based on granular (100m x 100m) area, population and land use data provided by the European Commission's Joint Research Center.

Computes various geospatial indices of socioeconomic deprivation and disparity in the United States. Some indices are considered "spatial" because they consider the values of neighboring (i.e., adjacent) census geographies in their computation, while other indices are "aspatial" because they only consider the value within each census geography. Two types of aspatial neighborhood deprivation indices (NDI) are available, including: (1) based on Messer et al. (2006) <doi:10.1007/s11524-006-9094-x> and (2) based on Andrews et al. (2020) <doi:10.1080/17445647.2020.1750066> and Slotman et al. (2022) <doi:10.1016/j.dib.2022.108002> who use variables chosen by Roux and Mair (2010) <doi:10.1111/j.1749-6632.2009.05333.x>. Both are a decomposition of multiple demographic characteristics from the U.S. Census Bureau American Community Survey 5-year estimates (ACS-5; 2006-2010 onward). Using data from the ACS-5 (2005-2009 onward), the package can also compute indices of racial or ethnic residential segregation, including but limited to those discussed in Massey & Denton (1988) <doi:10.1093/sf/67.2.281>, and additional indices of socioeconomic disparity.

This package provides a small package designed for interpreting continuous and categorical latent variables. You provide a data set with a latent variable you want to understand and some other explanatory variables. It provides a description of the latent variable based on the explanatory variables. It also provides a name to the latent variable.

This package provides a graph visualization engine that emphasizes on aesthetics at the same time providing default parameters that yield out-of-the-box-nice visualizations. The package is built on top of The Grid Graphics Package and seamlessly work with igraph and network objects.

Estimate the non-linear odds ratio and plot it against a continuous exposure.