This package implements a procedure for forecasting time series data based on an additive model where non-linear trends are fit with yearly, weekly, and daily seasonality, plus holiday effects. It works best with time series that have strong seasonal effects and several seasons of historical data. Prophet is robust to missing data and shifts in the trend, and typically handles outliers well.

This package provides tools for cross-validated Lasso and Post-Lasso estimation. Built on top of the glmnet package by Friedman, Hastie and Tibshirani (2010) <doi:10.18637/jss.v033.i01>, the main function plasso() extends the standard glmnet output with coefficient paths for Post-Lasso models, while cv.plasso() performs cross-validation for both Lasso and Post-Lasso models and different ways to select the penalty parameter lambda as discussed in Knaus (2021) <doi:10.1111/rssa.12623>.

Application of the Partitioning-Around-Medoids (PAM) clustering algorithm described in Schubert, E. and Rousseeuw, P.J.: "Fast and eager k-medoids clustering: O(k) runtime improvement of the PAM, CLARA, and CLARANS algorithms." Information Systems, vol. 101, p. 101804, (2021). <doi:10.1016/j.is.2021.101804>. It uses a binary format for storing and retrieval of matrices developed for the jmatrix package but the functionality of jmatrix is included here, so you do not need to install it. Also, it is used by package scellpam', so if you have installed it, you do not need to install this package. PAM can be applied to sets of data whose dissimilarity matrix can be very big. It has been tested with up to 100.000 points. It does this with the help of the code developed for other package, jmatrix', which allows the matrix not to be loaded in R memory (which would force it to be of double type) but it gets from disk, which allows using float (or even smaller data types). Moreover, the dissimilarity matrix is calculated in parallel if the computer has several cores so it can open many threads. The initial part of the PAM algorithm can be done with the BUILD or LAB algorithms; the BUILD algorithm has been implemented in parallel. The optimization phase implements the FastPAM1 algorithm, also in parallel. Finally, calculation of silhouette is available and also implemented in parallel.

Simplify your portfolio optimization process by applying a contemporary modeling way to model and solve your portfolio problems. While most approaches and packages are rather complicated this one tries to simplify things and is agnostic regarding risk measures as well as optimization solvers. Some of the methods implemented are described by Konno and Yamazaki (1991) <doi:10.1287/mnsc.37.5.519>, Rockafellar and Uryasev (2001) <doi:10.21314/JOR.2000.038> and Markowitz (1952) <doi:10.1111/j.1540-6261.1952.tb01525.x>.

The Prognostic Regression Offsets with Propagation of ERrors (for Treatment Effect Estimation) package facilitates direct adjustment for experiments and observational studies that is compatible with a range of study designs and covariance adjustment strategies. It uses explicit specification of clusters, blocks and treatment allocations to furnish probability of assignment-based weights targeting any of several average treatment effect parameters, and for standard error calculations reflecting these design parameters. For covariance adjustment of its Hajek and (one-way) fixed effects estimates, it enables offsetting the outcome against predictions from a dedicated covariance model, with standard error calculations propagating error as appropriate from the covariance model.

Transforms datetime data into a format ready for analysis. It offers two core functionalities; aggregating data to a higher level interval (thicken) and imputing records where observations were absent (pad).

Gene-based association tests using the actual impurity reduction (AIR) variable importance. The function aggregates AIR importance measures from a group of SNPs or probes and outputs a p-value for each gene. The procedures builds upon the method described in <doi:10.1093/Bioinformatics/Bty373> and will be published soon.

Download, parses and tidies information from the World Prison Brief project <http://www.prisonstudies.org/>.

Computes the exact probability density function of X/Y conditioned on positive quadrant for series of bivariate distributions,for more details see Nadarajah,Song and Si (2019) <DOI:10.1080/03610926.2019.1576893>.

Using Electronic Health Record (EHR) is difficult because most of the time the true characteristic of the patient is not available. Instead we can retrieve the International Classification of Disease code related to the disease of interest or we can count the occurrence of the Unified Medical Language System. None of them is the true phenotype which needs chart review to identify. However chart review is time consuming and costly. PheVis is an algorithm which is phenotyping (i.e identify a characteristic) at the visit level in an unsupervised fashion. It can be used for chronic or acute diseases. An example of how to use PheVis is available in the vignette. Basically there are two functions that are to be used: `train_phevis()` which trains the algorithm and `test_phevis()` which get the predicted probabilities. The detailed method is described in preprint by Ferté et al. (2020) <doi:10.1101/2020.06.15.20131458>.

This package provides a comprehensive collection of tools for creating, manipulating and visualising pedigrees and genetic marker data. Pedigrees can be read from text files or created on the fly with built-in functions. A range of utilities enable modifications like adding or removing individuals, breaking loops, and merging pedigrees. An online tool for creating pedigrees interactively, based on pedtools', is available at <https://magnusdv.shinyapps.io/quickped>. pedtools is the hub of the pedsuite', a collection of packages for pedigree analysis. A detailed presentation of the pedsuite is given in the book Pedigree Analysis in R (Vigeland, 2021, ISBN:9780128244302).

This package provides tools for Bayesian estimation of meta-analysis models that account for publications bias or p-hacking. For publication bias, this package implements a variant of the p-value based selection model of Hedges (1992) <doi:10.1214/ss/1177011364> with discrete selection probabilities. It also implements the mixture of truncated normals model for p-hacking described in Moss and De Bin (2019) <arXiv:1911.12445>.

Following Sommer (2022) <https://mediatum.ub.tum.de/1658240> portfolio level risk estimates (e.g. Value at Risk, Expected Shortfall) are estimated by modeling each asset univariately by an ARMA-GARCH model and then their cross dependence via a Vine Copula model in a rolling window fashion. One can even condition on variables/time series at certain quantile levels to stress test the risk measure estimates.

Bayesian toolbox for quantitative proteomics. In particular, this package provides functions to generate synthetic datasets, execute Bayesian differential analysis methods, and display results as, described in the associated article Marie Chion and Arthur Leroy (2023) <arXiv:2307.08975>.

Installs an updated version of pomdp-solve', a program to solve Partially Observable Markov Decision Processes (POMDPs) using a variety of exact and approximate value iteration algorithms. A convenient R infrastructure is provided in the separate package pomdp. Kaelbling, Littman and Cassandra (1998) <doi:10.1016/S0004-3702(98)00023-X>.

This package provides a RStudio addin allowing to paste the content of the clipboard as a comment block or as roxygen lines. This is very useful to insert an example in the roxygen block.

Identifies potential target sequences for a given set of primers and generates phylogenetic trees annotated with the taxonomies of the predicted amplification products.

Allows biomechanical pressure data from a range of systems to be imported and processed in a reproducible manner. Automatic and manual tools are included to let the user define regions (masks) to be analyzed. Also includes functions for visualizing and animating pressure data. Example methods are described in Shi et al., (2022) <doi:10.1038/s41598-022-19814-0>, Lee et al., (2014) <doi:10.1186/1757-1146-7-18>, van der Zward et al., (2014) <doi:10.1186/1757-1146-7-20>, Najafi et al., (2010) <doi:10.1016/j.gaitpost.2009.09.003>, Cavanagh and Rodgers (1987) <doi:10.1016/0021-9290(87)90255-7>.

This package provides tools for statistical testing of correlation coefficients through robust permutation method and large sample approximation method. Tailored to different types of correlation coefficients including Pearson correlation coefficient, weighted Pearson correlation coefficient, Spearman correlation coefficient, and Lin's concordance correlation coefficient.The robust permutation test controls type I error under general scenarios when sample size is small and two variables are dependent but uncorrelated. The large sample approximation test generally controls type I error when the sample size is large (>200).

This package contains the functions for construction and visualization of underlying and reflexivity graphs of the three families of the proximity catch digraphs (PCDs), see (Ceyhan (2005) ISBN:978-3-639-19063-2), and for computing the edge density of these PCD-based graphs which are then used for testing the patterns of segregation and association against complete spatial randomness (CSR)) or uniformity in one and two dimensional cases. The PCD families considered are Arc-Slice PCDs, Proportional-Edge (PE) PCDs (Ceyhan et al. (2006) <doi:10.1016/j.csda.2005.03.002>) and Central Similarity PCDs (Ceyhan et al. (2007) <doi:10.1002/cjs.5550350106>). See also (Ceyhan (2016) <doi:10.1016/j.stamet.2016.07.003>) for edge density of the underlying and reflexivity graphs of PE-PCDs. The package also has tools for visualization of PCD-based graphs for one, two, and three dimensional data.

We included functions to assess the performance of risk models. The package contains functions for the various measures that are used in empirical studies, including univariate and multivariate odds ratios (OR) of the predictors, the c-statistic (or area under the receiver operating characteristic (ROC) curve (AUC)), Hosmer-Lemeshow goodness of fit test, reclassification table, net reclassification improvement (NRI) and integrated discrimination improvement (IDI). Also included are functions to create plots, such as risk distributions, ROC curves, calibration plot, discrimination box plot and predictiveness curves. In addition to functions to assess the performance of risk models, the package includes functions to obtain weighted and unweighted risk scores as well as predicted risks using logistic regression analysis. These logistic regression functions are specifically written for models that include genetic variables, but they can also be applied to models that are based on non-genetic risk factors only. Finally, the package includes function to construct a simulated dataset with genotypes, genetic risks, and disease status for a hypothetical population, which is used for the evaluation of genetic risk models.

This package provides a system contains easy-to-use tools for the conditional estimation of the prevalence of an emerging or rare infectious diseases using the methods proposed in Guerrier et al. (2023) <arXiv:2012.10745>.

This package provides functions for bootstrapping the power of ANOVA designs based on estimated means and standard deviations of the conditions. Please refer to the documentation of the boot.power.anova() function for further details.

Consider a possibly nonlinear nonparametric regression with p regressors. We provide evaluations by 13 methods to rank regressors by their practical significance or importance using various methods, including machine learning tools. Comprehensive methods are as follows. m6=Generalized partial correlation coefficient or GPCC by Vinod (2021)<doi:10.1007/s10614-021-10190-x> and Vinod (2022)<https://www.mdpi.com/1911-8074/15/1/32>. m7= a generalization of psychologists effect size incorporating nonlinearity and many variables. m8= local linear partial (dy/dxi) using the np package for kernel regressions. m9= partial (dy/dxi) using the NNS package. m10= importance measure using the NNS boost function. m11= Shapley Value measure of importance (cooperative game theory). m12 and m13= two versions of the random forest algorithm. Taraldsen's exact density for sampling distribution of correlations added.