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Runs generalized and multinominal logistic (GLM and MLM) models, as well as random forest (RF), Bagging (BAG), and Boosting (BOOST). This package prints out to predictive outcomes easy for the selected data and data splits.
Compiles functions to trim, bin, visualise, and analyse activity/sleep time-series data collected from the Drosophila Activity Monitor (DAM) system (Trikinetics, USA). The following methods were used to compute periodograms - Chi-square periodogram: Sokolove and Bushell (1978) <doi:10.1016/0022-5193(78)90022-X>, Lomb-Scargle periodogram: Lomb (1976) <doi:10.1007/BF00648343>, Scargle (1982) <doi:10.1086/160554> and Ruf (1999) <doi:10.1076/brhm.30.2.178.1422>, and Autocorrelation: Eijzenbach et al. (1986) <doi:10.1111/j.1440-1681.1986.tb00943.x>. Identification of activity peaks is done after using a Savitzky-Golay filter (Savitzky and Golay (1964) <doi:10.1021/ac60214a047>) to smooth raw activity data. Three methods to estimate anticipation of activity are used based on the following papers - Slope method: Fernandez et al. (2020) <doi:10.1016/j.cub.2020.04.025>, Harrisingh method: Harrisingh et al. (2007) <doi:10.1523/JNEUROSCI.3680-07.2007>, and Stoleru method: Stoleru et al. (2004) <doi:10.1038/nature02926>. Rose plots and circular analysis are based on methods from - Batschelet (1981) <ISBN:0120810506> and Zar (2010) <ISBN:0321656865>.
Using the R package reticulate', this package creates an interface to the pysd toolset. The package provides an R interface to a number of pysd functions, and can read files in Vensim mdl format, and xmile format. The resulting simulations are returned as a tibble', and from that the results can be processed using dplyr and ggplot2'. The package has been tested using python3'.
Assessment for statistically-based PPQ sampling plan, including calculating the passing probability, optimizing the baseline and high performance cutoff points, visualizing the PPQ plan and power dynamically. The analytical idea is based on the simulation methods from the textbook Burdick, R. K., LeBlond, D. J., Pfahler, L. B., Quiroz, J., Sidor, L., Vukovinsky, K., & Zhang, L. (2017). Statistical Methods for CMC Applications. In Statistical Applications for Chemistry, Manufacturing and Controls (CMC) in the Pharmaceutical Industry (pp. 227-250). Springer, Cham.
This package provides functions for graph-based multiple-sample testing and visualization of microbiome data, in particular data stored in phyloseq objects. The tests are based on those described in Friedman and Rafsky (1979) <http://www.jstor.org/stable/2958919>, and the tests are described in more detail in Callahan et al. (2016) <doi:10.12688/f1000research.8986.1>.
Parallel Constraint Satisfaction (PCS) models are an increasingly common class of models in Psychology, with applications to reading and word recognition (McClelland & Rumelhart, 1981), judgment and decision making (Glöckner & Betsch, 2008; Glöckner, Hilbig, & Jekel, 2014), and several other fields (e.g. Read, Vanman, & Miller, 1997). In each of these fields, they provide a quantitative model of psychological phenomena, with precise predictions regarding choice probabilities, decision times, and often the degree of confidence. This package provides the necessary functions to create and simulate basic Parallel Constraint Satisfaction networks within R.
Includes functions for keyword search of pdf files. There is also a wrapper that includes searching of all files within a single directory.
This package provides functions that facilitate the elaboration of population pyramids.
This package provides a comprehensive framework for model fitting and simulation of drug release kinetics, pharmacokinetics (PK), and pharmacodynamics (PD). The package implements widely used mechanistic and empirical models for in vitro drug release, including zero-order, first-order, Higuchi, Korsmeyer-Peppas, Hixson-Crowell, and Weibull models. Pharmacokinetic functionality includes linear and nonlinear functions for one- and two-compartment models for intravenous bolus and oral administration, Michaelis-Menten kinetics, and non-compartmental analysis (NCA). Pharmacodynamic and dose-response modeling is supported through Emax-based models, including stimulatory (sigmoid Emax) and inhibitory (sigmoid Imax) Hill models, four- and five-parameter logistic models, as well as median toxic dose (TD50) and lethal dose (LD50) models. The package is intended to support parameter estimation, simulation, and model comparison in pharmaceutical research, drug development, and pharmacometrics education. For more details, see Gabrielsson & Weiner (2000) <ISBN:9186274929>, Holford & Sheiner (1981) <doi:10.2165/00003088-198106060-00002>, and Manlapaz (2025) <doi:10.32614/CRAN.package.adsoRptionCMF>.
This package provides function for performing Bayesian survival regression using Horseshoe prior in the accelerated failure time model with log normal assumption in order to achieve high dimensional pan-cancer variable selection as developed in Maity et. al. (2019) <doi:10.1111/biom.13132>.
Gives the ability to automatically deploy a plumber API from R functions on DigitalOcean and other cloud-based servers.
Density, distribution function, quantile function, and random generation function based on Kittipong Klinjan,Tipat Sottiwan and Sirinapa Aryuyuen (2024)<DOI:10.28919/cmbn/8833>.
This package provides software to facilitate the design, testing, and operation of computer models. It focuses particularly on tools that make it easy to construct and edit a customized graphical user interface ('GUI'). Although our simplified GUI language depends heavily on the R interface to the Tcl/Tk package, a user does not need to know Tcl/Tk'. Examples illustrate models built with other R packages, including PBSmapping', PBSddesolve', and BRugs'. A complete user's guide PBSmodelling-UG.pdf shows how to use this package effectively.
Fits Bayesian mixture models to estimate marker dosage for dominant markers in autopolyploids using JAGS (1.0 or greater) as outlined in Baker et al "Bayesian estimation of marker dosage in sugarcane and other autopolyploids" (2010, <doi:10.1007/s00122-010-1283-z>). May be used in conjunction with polySegratio for simulation studies and comparison with standard methods.
It aggregates protein panel data and metadata for protein quantitative trait locus (pQTL) analysis using pQTLtools (<https://jinghuazhao.github.io/pQTLtools/>). The package includes data from affinity-based panels such as Olink (<https://olink.com/>) and SomaScan (<https://somalogic.com/>), as well as mass spectrometry-based panels from CellCarta (<https://cellcarta.com/>) and Seer (<https://seer.bio/>). The metadata encompasses updated annotations and publication details.
Sample size calculations for practical equivalence trial design with a time to event endpoint.
This package provides functions for working with primary event censored distributions and Stan implementations for use in Bayesian modeling. Primary event censored distributions are useful for modeling delayed reporting scenarios in epidemiology and other fields (Charniga et al. (2024) <doi:10.48550/arXiv.2405.08841>). It also provides support for arbitrary delay distributions, a range of common primary distributions, and allows for truncation and secondary event censoring to be accounted for (Park et al. (2024) <doi:10.1101/2024.01.12.24301247>). A subset of common distributions also have analytical solutions implemented, allowing for faster computation. In addition, it provides multiple methods for fitting primary event censored distributions to data via optional dependencies.
Determine the chlorophyll a (Chl a) concentrations of different phytoplankton groups based on their pigment biomarkers. The method uses non-negative matrix factorisation and simulated annealing to minimise error between the observed and estimated values of pigment concentrations (Hayward et al. (2023) <doi:10.1002/lom3.10541>). The approach is similar to the widely used CHEMTAX program (Mackey et al. 1996) <doi:10.3354/meps144265>, but is more straightforward, accurate, and not reliant on initial guesses for the pigment to Chl a ratios for phytoplankton groups.
This package provides high-level API and a wide range of options to create stunning, publication-quality plots effortlessly. It is built upon ggplot2 and other plotting packages, and is designed to be easy to use and to work seamlessly with ggplot2 objects. It is particularly useful for creating complex plots with multiple layers, facets, and annotations. It also provides a set of functions to create plots for specific types of data, such as Venn diagrams, alluvial diagrams, and phylogenetic trees. The package is designed to be flexible and customizable, and to work well with the ggplot2 ecosystem. The API can be found at <https://pwwang.github.io/plotthis/reference/index.html>.
The PROMETHEE method is a multi-criteria decision-making method addressing with outranking problems. The method establishes a preference structure between the alternatives, having a preference function for each criterion. IN this context, three variants of the method is carried out: PROMETHEE I (Partial Outranking), PROMETHEE II (Total Outranking), and PROMETHEE III (Outranking by Intervals).
This package provides a method for the quantitative prediction with much predictors. This package provides functions to construct the quantitative prediction model with less overfitting and robust to noise.
This package provides tools for estimating model-agnostic prediction intervals using conformal prediction, bootstrapping, and parametric prediction intervals. The package is designed for ease of use, offering intuitive functions for both binned and full conformal prediction methods, as well as parametric interval estimation with diagnostic checks. Currently only working for continuous predictions. For details on the conformal and bin-conditional conformal prediction methods, see Randahl, Williams, and Hegre (2024) <DOI:10.48550/arXiv.2410.14507>.
Probabilistic factor analysis for spatially-aware dimension reduction across multi-section spatial transcriptomics data with millions of spatial locations. More details can be referred to Wei Liu, et al. (2023) <doi:10.1101/2023.07.11.548486>.
It enables sparklyr to integrate with Spark Connect', and Databricks Connect by providing a wrapper over the PySpark python library.