An environment to simulate the development of annual plant populations with regard to population dynamics and genetics, especially herbicide resistance. It combines genetics on the individual level (Renton et al. 2011) with a stochastic development on the population level (Daedlow, 2015). Renton, M, Diggle, A, Manalil, S and Powles, S (2011) <doi:10.1016/j.jtbi.2011.05.010> Daedlow, Daniel (2015, doctoral dissertation: University of Rostock, Faculty of Agriculture and Environmental Sciences.).

This package implements a Bayesian profile regression using a generalized linear mixed model as output model. The package allows for binary (probit mixed model) and continuous (linear mixed model) outcomes and both continuous and categorical clustering variables. The package utilizes RcppArmadillo and RcppDist for high-performance statistical computing in C++. For more details see Amestoy & al. (2025) <doi:10.48550/arXiv.2510.08304>.

An add-on to the party package, with a faster implementation of the partial-conditional permutation importance for random forests. The standard permutation importance is implemented exactly the same as in the party package. The conditional permutation importance can be computed faster, with an option to be backward compatible to the party implementation. The package is compatible with random forests fit using the party and the randomForest package. The methods are described in Strobl et al. (2007) <doi:10.1186/1471-2105-8-25> and Debeer and Strobl (2020) <doi:10.1186/s12859-020-03622-2>.

Useful for preparing and cleaning data. It includes functions to center data, reverse coding, dummy code and effect code data, and more.

Mixtures of Poisson Generalized Linear Models for high dimensional count data clustering. The (multivariate) responses can be partitioned into set of blocks. Three different parameterizations of the linear predictor are considered. The models are estimated according to the EM algorithm with an efficient initialization scheme <doi:10.1016/j.csda.2014.07.005>.

Streamlines the steps for adding colour scales and associated legends when working with base R graphics, especially for interactive use. Popular palettes are included and pretty legends produced when mapping a large variety of vector classes to a colour scale. An additional helper for adding axes and grid lines complements the base::plot() work flow.

Supports propensity score weighting analysis of observational studies and randomized trials. Enables the estimation and inference of average causal effects with binary and multiple treatments using overlap weights (ATO), inverse probability of treatment weights (ATE), average treatment effect among the treated weights (ATT), matching weights (ATM) and entropy weights (ATEN), with and without propensity score trimming. These weights are members of the family of balancing weights introduced in Li, Morgan and Zaslavsky (2018) <doi:10.1080/01621459.2016.1260466> and Li and Li (2019) <doi:10.1214/19-AOAS1282>.

This package provides a package for selecting the most relevant features (genes) in the high-dimensional binary classification problems. The discriminative features are identified using analyzing the overlap between the expression values across both classes. The package includes functions for measuring the proportional overlapping score for each gene avoiding the outliers effect. The used measure for the overlap is the one defined in the "Proportional Overlapping Score (POS)" technique for feature selection. A gene mask which represents a gene's classification power can also be produced for each gene (feature). The set size of the selected genes might be set by the user. The minimum set of genes that correctly classify the maximum number of the given tissue samples (observations) can be also produced.

This package provides functions for modeling, comparing, and visualizing photosynthetic light response curves using established mechanistic and empirical models like the rectangular hyperbola Michaelis-Menton based models ((eq1 (Baly (1935) <doi:10.1098/rspb.1935.0026>)) (eq2 (Kaipiainenn (2009) <doi:10.1134/S1021443709040025>)) (eq3 (Smith (1936) <doi:10.1073/pnas.22.8.504>))), hyperbolic tangent based models ((eq4 (Jassby & Platt (1976) <doi:10.4319/LO.1976.21.4.0540>)) (eq5 (Abe et al. (2009) <doi:10.1111/j.1444-2906.2008.01619.x>))), the non-rectangular hyperbola model (eq6 (Prioul & Chartier (1977) <doi:10.1093/oxfordjournals.aob.a085354>)), exponential based models ((eq8 (Webb et al. (1974) <doi:10.1007/BF00345747>)), (eq9 (Prado & de Moraes (1997) <doi:10.1007/BF02982542>))), and finally the Ye model (eq11 (Ye (2007) <doi:10.1007/s11099-007-0110-5>)). Each of these nonlinear least squares models are commonly used to express photosynthetic response under changing light conditions and has been well supported in the literature, but distinctions in each mathematical model represent moderately different assumptions about physiology and trait relationships which ultimately produce different calculated functional trait values. These models were all thoughtfully discussed and curated by Lobo et al. (2013) <doi:10.1007/s11099-013-0045-y> to express the importance of selecting an appropriate model for analysis, and methods were established in Davis et al. (in review) to evaluate the impact of analytical choice in phylogenetic analysis of the function-valued traits. Gas exchange data on 28 wild sunflower species from Davis et al.are included as an example data set here.

Includes functions and data used in the book "Presenting Statistical Results Effectively", Andersen and Armstrong (2022, ISBN: 978-1446269800). Several functions aid in data visualization - creating compact letter displays for simple slopes, kernel density estimates with normal density overlay. Other functions aid in post-model evaluation heatmap fit statistics for binary predictors, several variable importance measures, compact letter displays and simple-slope calculation. Finally, the package makes available the example datasets used in the book.

Proteins reside in either the cell plasma or in the cell membrane. A membrane protein goes through the membrane at least once. Given the amino acid sequence of a membrane protein, the tool PureseqTM (<https://github.com/PureseqTM/pureseqTM_package>, as described in "Efficient And Accurate Prediction Of Transmembrane Topology From Amino acid sequence only.", Wang, Qing, et al (2019), <doi:10.1101/627307>), can predict the topology of a membrane protein. This package allows one to use PureseqTM from R.

Reproducible, programmatic retrieval of survey datasets from the Pew Research Center.

This package provides methods for fitting point processes with parameters of generalised additive model (GAM) form are provided. For an introduction to point processes see Cox, D.R & Isham, V. (Point Processes, 1980, CRC Press), GAMs see Wood, S.N. (2017) <doi:10.1201/9781315370279>, and the fitting approach see Wood, S.N., Pya, N. & Safken, B. (2016) <doi:10.1080/01621459.2016.1180986>.

This package provides tools for downloading, reading and analyzing the Continuous National Household Sample Survey - PNADC, a household survey from Brazilian Institute of Geography and Statistics - IBGE. The data must be downloaded from the official website <https://www.ibge.gov.br/>. Further analysis must be made using package survey'.

We implement two least-squares estimators under k-monotony constraint using a method based on the Support Reduction Algorithm from Groeneboom et al (2008) <DOI:10.1111/j.1467-9469.2007.00588.x>. The first one is a projection estimator on the set of k-monotone discrete functions. The second one is a projection on the set of k-monotone discrete probabilities. This package provides functions to generate samples from the spline basis from Lefevre and Loisel (2013) <DOI:10.1239/jap/1378401239>, and from mixtures of splines.

PHATE is a tool for visualizing high dimensional single-cell data with natural progressions or trajectories. PHATE uses a novel conceptual framework for learning and visualizing the manifold inherent to biological systems in which smooth transitions mark the progressions of cells from one state to another. To see how PHATE can be applied to single-cell RNA-seq datasets from hematopoietic stem cells, human embryonic stem cells, and bone marrow samples, check out our publication in Nature Biotechnology at <doi:10.1038/s41587-019-0336-3>.

Fits single- and multiple-group penalized factor analysis models via a trust-region algorithm with integrated automatic multiple tuning parameter selection (Geminiani et al., 2021 <doi:10.1007/s11336-021-09751-8>). Available penalties include lasso, adaptive lasso, scad, mcp, and ridge.

R has no built-in pointer functionality. The pointr package fills this gap and lets you create pointers to R objects, including subsets of dataframes. This makes your R code more readable and maintainable.

Identifies differences between versions of a package. Specifically, the functions help determine if there are breaking changes from one package version to the next. The package also includes a stability assessment, to help you determine the overall stability of a package, or even an entire repository.

Allows the comparison of data cohorts (DC) against a Counter Factual Model (CFM) and measures the difference in terms of an efficacy parameter. Allows the application of Personalised Synthetic Controls.

This package provides a collection of tools to facilitate standardized analysis and graphical procedures when using the National Cancer Instituteâ s Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) and other PRO measurements.

Provide estimation for particular cases of the power series cure rate model <doi:10.1080/03610918.2011.639971>. For the distribution of the concurrent causes the alternative models are the Poisson, logarithmic, negative binomial and Bernoulli (which are includes in the original work), the polylogarithm model <doi:10.1080/00949655.2018.1451850> and the Flory-Schulz <doi:10.3390/math10244643>. The estimation procedure is based on the EM algorithm discussed in <doi:10.1080/03610918.2016.1202276>. For the distribution of the time-to-event the alternative models are slash half-normal, Weibull, gamma and Birnbaum-Saunders distributions.

Fast exponentiation when the exponent is an integer.

Estimation of univariate (conditional) densities using penalized B-splines with automatic selection of optimal smoothing parameter.