This package provides a software package to perform Wombling, or boundary analysis, using the nimble Bayesian hierarchical modeling environment. Wombling is used widely to track regions of rapid change within the spatial reference domain. Specific functions in the package implement Gaussian process models for point-referenced spatial data followed by predictive inference on rates of change over curves using line integrals. We demonstrate model based Bayesian inference using posterior distributions featuring simple analytic forms while offering uncertainty quantification over curves. For more details on wombling please see, Banerjee and Gelfand (2006) <doi:10.1198/016214506000000041> and Halder, Banerjee and Dey (2024) <doi:10.1080/01621459.2023.2177166>.

This package implements methods for centrality related analyses of networks. While the package includes the possibility to build more than 20 indices, its main focus lies on index-free assessment of centrality via partial rankings obtained by neighborhood-inclusion or positional dominance. These partial rankings can be analyzed with different methods, including probabilistic methods like computing expected node ranks and relative rank probabilities (how likely is it that a node is more central than another?). The methodology is described in depth in the vignettes and in Schoch (2018) <doi:10.1016/j.socnet.2017.12.003>.

NEON data packages can be accessed through the NEON Data Portal <https://www.neonscience.org> or through the NEON Data API (see <https://data.neonscience.org/data-api> for documentation). Data delivered from the Data Portal are provided as monthly zip files packaged within a parent zip file, while individual files can be accessed from the API. This package provides tools that aid in discovering, downloading, and reformatting data prior to use in analyses. This includes downloading data via the API, merging data tables by type, and converting formats. For more information, see the readme file at <https://github.com/NEONScience/NEON-utilities>.

This is an R implementation of the netinf algorithm (Gomez Rodriguez, Leskovec, and Krause, 2010)<doi:10.1145/1835804.1835933>. Given a set of events that spread between a set of nodes the algorithm infers the most likely stable diffusion network that is underlying the diffusion process.

This package performs nonparametric estimation in mixture cure models when the cure status is partially known. For details, see Safari et al (2021) <doi:10.1002/bimj.202100156>, Safari et al (2022) <doi:10.1177/09622802221115880> and Safari et al (2023) <doi:10.1007/s10985-023-09591-x>.

Waiting list management using queuing theory to analyse, predict and manage queues, based on the approach described in Fong et al. (2022) <doi:10.1101/2022.08.23.22279117>. Aimed at UK National Health Service (NHS) applications, waiting list summary statistics, target-value calculations, waiting list simulation, and scheduling functions are included.

Utilities for unambiguous, neat and legible representation of data (date, time stamp, numbers, percentages and strings) for presentation of analysis , aiming for elegance and consistency. The purpose of this package is to format data, that is better for presentation and any automation jobs that reports numbers.

Implementation of the NetCutter algorithm described in Müller and Mancuso (2008) <doi:10.1371/journal.pone.0003178>. The package identifies co-occurring terms in a list of containers. For example, it may be used to detect genes that co-occur across genomes.

To estimate ecological stochasticity in community assembly. Understanding the community assembly mechanisms controlling biodiversity patterns is a central issue in ecology. Although it is generally accepted that both deterministic and stochastic processes play important roles in community assembly, quantifying their relative importance is challenging. The new index, normalized stochasticity ratio (NST), is to estimate ecological stochasticity, i.e. relative importance of stochastic processes, in community assembly. With functions in this package, NST can be calculated based on different similarity metrics and/or different null model algorithms, as well as some previous indexes, e.g. previous Stochasticity Ratio (ST), Standard Effect Size (SES), modified Raup-Crick metrics (RC). Functions for permutational test and bootstrapping analysis are also included. Previous ST is published by Zhou et al (2014) <doi:10.1073/pnas.1324044111>. NST is modified from ST by considering two alternative situations and normalizing the index to range from 0 to 1 (Ning et al 2019) <doi:10.1073/pnas.1904623116>. A modified version, MST, is a special case of NST, used in some recent or upcoming publications, e.g. Liang et al (2020) <doi:10.1016/j.soilbio.2020.108023>. SES is calculated as described in Kraft et al (2011) <doi:10.1126/science.1208584>. RC is calculated as reported by Chase et al (2011) <doi:10.1890/ES10-00117.1> and Stegen et al (2013) <doi:10.1038/ismej.2013.93>. Version 3 added NST based on phylogenetic beta diversity, used by Ning et al (2020) <doi:10.1038/s41467-020-18560-z>.

Density, distribution function, quantile function and random generation for the 3D Navarro, Frenk & White (NFW) profile. For details see Robotham & Howlett (2018) <arXiv:1805.09550>.

User-friendly functions for extracting a data table (row for each match, column for each group) from non-tabular text data using regular expressions, and for melting columns that match a regular expression. Patterns are defined using a readable syntax that makes it easy to build complex patterns in terms of simpler, re-usable sub-patterns. Named R arguments are translated to column names in the output; capture groups without names are used internally in order to provide a standard interface to three regular expression C libraries ('PCRE', RE2', ICU'). Output can also include numeric columns via user-specified type conversion functions.

Measure the dependence structure between two random variables with a new correlation coefficient and extend it to hypothesis test, feature screening and false discovery rate control.

Offers a rich and diverse collection of datasets focused on the brain, nervous system, and related disorders. The package includes clinical, experimental, neuroimaging, behavioral, cognitive, and simulated data on conditions such as Parkinson's disease, Alzheimer's disease, dementia, epilepsy, schizophrenia, autism spectrum disorder, attention deficit, hyperactivity disorder, Tourette's syndrome, traumatic brain injury, gliomas, migraines, headaches, sleep disorders, concussions, encephalitis, subarachnoid hemorrhage, and mental health conditions. Datasets cover structural and functional brain data, cross-sectional and longitudinal MRI imaging studies, neurotransmission, gene expression, cognitive performance, intelligence metrics, sleep deprivation effects, treatment outcomes, brain-body relationships across species, neurological injury patterns, and acupuncture interventions. Data sources include peer-reviewed studies, clinical trials, military health records, sports injury databases, and international comparative studies. Designed for researchers, neuroscientists, clinicians, psychologists, data scientists, and students, this package facilitates exploratory data analysis, statistical modeling, and hypothesis testing in neuroscience and neuroepidemiology. The package includes datasets originally distributed in other R packages as well as open data repositories such as Kaggle. Original package authors and contributors are acknowledged in Authors@R. All datasetsâ including those from R source packages and Kaggle, along with their respective authors and licensing termsâ are fully documented in the LICENSES_DETAILS file.

Routines for enumerating all existing nonnegative integer solutions of a linear Diophantine equation. The package provides routines for solving 0-1, bounded and unbounded knapsack problems; 0-1, bounded and unbounded subset sum problems; additive partitioning of natural numbers; and one-dimensional bin-packing problem.

We proposed a package for the classification task which uses Negative Binomial distribution within Linear Discriminant Analysis (NBLDA). It is an extension of the PoiClaClu package to Negative Binomial distribution. The classification algorithms are based on the papers Dong et al. (2016, ISSN: 1471-2105) and Witten, DM (2011, ISSN: 1932-6157) for NBLDA and PLDA, respectively. Although PLDA is a sparse algorithm and can be used for variable selection, the algorithm proposed by Dong et al. is not sparse. Therefore, it uses all variables in the classifier. Here, we extend Dong et al.'s algorithm to the sparse case by shrinking overdispersion towards 0 (Yu et al., 2013, ISSN: 1367-4803) and offset parameter towards 1 (as proposed by Witten DM, 2011). We support only the classification task with this version.

Formats student records for submission to the National Student Clearinghouse. The package creates the required header, detail, and trailer rows and writes tab-delimited TXT and CSV files.

This package provides efficient implementation of the Narrowest-Over-Threshold methodology for detecting an unknown number of change-points occurring at unknown locations in one-dimensional data following deterministic signal + noise model. Currently implemented scenarios are: piecewise-constant signal, piecewise-constant signal with a heavy-tailed noise, piecewise-linear signal, piecewise-quadratic signal, piecewise-constant signal and with piecewise-constant variance of the noise. For details, see Baranowski, Chen and Fryzlewicz (2019) <doi:10.1111/rssb.12322>.

Posterior distribution of case-control fine-mapping. Specifically, Bayesian variable selection for single-nucleotide polymorphism (SNP) data using the normal-gamma prior. Alenazi A.A., Cox A., Juarez M,. Lin W-Y. and Walters, K. (2019) Bayesian variable selection using partially observed categorical prior information in fine-mapping association studies, Genetic Epidemiology. <doi:10.1002/gepi.22213>.

Introduces a novel network-constrained survival analysis framework for variable selection and parameter estimation in penalized survival models with convex penalties. The package extends two classical survival models, the Cox Proportional Hazards (PH) model and the Accelerated Failure Time (AFT) model, by incorporating prior biological knowledge from curated interaction networks (e.g., KEGG) into a double-penalty framework. The first penalty enforces variable selection through a LASSO penalty, while the second preserves gene-gene correlations by incorporating Laplacian-based constraints, ensuring that biologically relevant network structures are maintained. Using censored survival data, the method enables the identification of predictive biomarkers and pathways with potential relevance for target therapies. Model estimation is performed via proximal optimization algorithms combined with cross-validation for reliable tuning. To enhance interpretability, dedicated utility functions are implemented to consolidate results, yielding biologically coherent insights that can support personalized medicine and contribute to improved patient outcomes.

Annotated neuroblastoma copy number profiles, a benchmark data set for change-point detection algorithms, as described by Hocking et al. <doi:10.1186/1471-2105-14-164>.

Utility functions that may be of general interest but are specifically required by the NeuroAnatomy Toolbox ('nat'). Includes functions to provide a basic make style system to update files based on timestamp information, file locking and touch utility. Convenience functions for working with file paths include abs2rel', split_path and common_path'. Finally there are utility functions for working with zip and gzip files including integrity tests.

Generates LaTeX code for drawing well-formatted neural network diagrams with TikZ'. Users have to define number of neurons on each layer, and optionally define neuron connections they would like to keep or omit, layers they consider to be oversized and neurons they would like to draw with lighter color. They can also specify the title of diagram, color, opacity of figure, labels of layers, input and output neurons. In addition, this package helps to produce LaTeX code for drawing activation functions which are crucial in neural network analysis. To make the code work in a LaTeX editor, users need to install and import some TeX packages including TikZ in the setting of TeX file.

This package provides a small multilayer perceptron implementation for R'. It supports regression and classification, multiple hidden layers, mini-batch training, Adam, SGD, momentum, Nesterov, RPROP, GRPROP and L-BFGS optimizers, dropout, L2 regularization, early stopping, convergence thresholds, gradient clipping, sample and class weights, callback hooks, target scaling and robust Huber loss for regression, Rcpp forward-pass kernels, formula interfaces, model evaluation with balanced classification metrics, cross-validation, compact tuning, permutation importance, model persistence helpers, and S3 prediction methods. Methods follow Rumelhart, Hinton and Williams (1986) <doi:10.1038/323533a0>, with optimizers including Riedmiller and Braun (1993) <doi:10.1109/ICNN.1993.298623>, Nocedal (1980) <doi:10.1090/S0025-5718-1980-0572855-7>, and Kingma and Ba (2014) <doi:10.48550/arXiv.1412.6980>.

Replacement for nls() tools for working with nonlinear least squares problems. The calling structure is similar to, but much simpler than, that of the nls() function. Moreover, where nls() specifically does NOT deal with small or zero residual problems, nlmrt is quite happy to solve them. It also attempts to be more robust in finding solutions, thereby avoiding singular gradient messages that arise in the Gauss-Newton method within nls(). The Marquardt-Nash approach in nlmrt generally works more reliably to get a solution, though this may be one of a set of possibilities, and may also be statistically unsatisfactory. Added print and summary as of August 28, 2012.