In empirical studies, instrumental variable (IV) regression is the signature method to solve the endogeneity problem. If we enforce the exogeneity condition of the IV, it is likely that we end up with a large set of IVs without knowing which ones are good. Also, one could face the model uncertainty for structural equation, as large micro dataset is commonly available nowadays. This package uses adaptive group lasso and B-spline methods to select the nonparametric components of the IV function, with the linear function being a special case (naivereg). The package also incorporates two stage least squares estimator (2SLS), generalized method of moment (GMM), generalized empirical likelihood (GEL) methods post instrument selection, logistic-regression instrumental variables estimator (LIVE, for dummy endogenous variable problem), double-selection plus instrumental variable estimator (DS-IV) and double selection plus logistic regression instrumental variable estimator (DS-LIVE), where the double selection methods are useful for high-dimensional structural equation models. The naivereg is nonparametric version of ivregress in Stata with IV selection and high dimensional features. The package is based on the paper by Q. Fan and W. Zhong, "Nonparametric Additive Instrumental Variable Estimator: A Group Shrinkage Estimation Perspective" (2018), Journal of Business & Economic Statistics <doi:10.1080/07350015.2016.1180991> as well as a series of working papers led by the same authors.

This package provides functions for the normal Laplace distribution. Currently, it provides limited functionality. Density, distribution and quantile functions, random number generation, and moments are provided.

Package for a Network assisted algorithm for Epigenetic studies using mean and variance Combined signals: NEpiC. NEpiC combines both signals in mean and variance differences in methylation level between case and control groups searching for differentially methylated sub-networks (modules) using the protein-protein interaction network.

Some functions for performing non-negative matrix factorization, non-negative CANDECOMP/PARAFAC (CP) decomposition, non-negative Tucker decomposition, and generating toy model data. See Andrzej Cichock et al (2009) and the reference section of GitHub README.md <https://github.com/rikenbit/nnTensor>, for details of the methods.

This package provides functions for reading cancer record files which follow a format defined by the North American Association of Central Cancer Registries (NAACCR).

Six growth models are fitted using non-linear least squares. These are the Richards, the 3, 4 and 5 parameter logistic, the Gompetz and the Weibull growth models. Reference: Reddy T., Shkedy Z., van Rensburg C. J., Mwambi H., Debba P., Zuma K. and Manda, S. (2021). "Short-term real-time prediction of total number of reported COVID-19 cases and deaths in South Africa: a data driven approach". BMC medical research methodology, 21(1), 1-11. <doi:10.1186/s12874-020-01165-x>.

This package provides methods to estimate finite-population parameters under nonresponse that is not missing at random (NMAR, nonignorable). Incorporates auxiliary information and user-specified response models, and supports independent samples and complex survey designs via objects from the survey package. Provides diagnostics and optional variance estimates. For methodological background see Qin, Leung and Shao (2002) <doi:10.1198/016214502753479338> and Riddles, Kim and Im (2016) <doi:10.1093/jssam/smv047>.

Nonnegative matrix factorization (NMF) is a technique to factorize a matrix with nonnegative values into the product of two matrices. Covariates are also allowed. Parallel computing is an option to enhance the speed and high-dimensional and large scale (and/or sparse) data are allowed. Relevant papers include: Sevinc V., Kontemeniotis N., Perdikis T. and Tsagris M. (2026). Non-negative matrix factorization using the R package nnmf <doi:10.48550/arXiv.2607.20084>, Wang Y. X. and Zhang Y. J. (2012). Nonnegative matrix factorization: A comprehensive review. IEEE Transactions on Knowledge and Data Engineering, 25(6): 1336-1353 <doi:10.1109/TKDE.2012.51> and Kim H. and Park H. (2008). Nonnegative matrix factorization based on alternating nonnegativity constrained least squares and active set method. SIAM Journal on Matrix Analysis and Applications, 30(2): 713-730 <doi:10.1137/07069239X>.

In this implementation of the Naive Bayes classifier following class conditional distributions are available: Bernoulli', Categorical', Gaussian', Poisson', Multinomial and non-parametric representation of the class conditional density estimated via Kernel Density Estimation. Implemented classifiers handle missing data and can take advantage of sparse data.

Neighbour-balanced designs ensure that no treatment is disadvantaged unfairly by its surroundings. The treatment allocation in these designs is such that every treatment appears equally often as a neighbour with every other treatment. Neighbour Balanced Designs are employed when there is a possibility of neighbour effects from treatments used in adjacent experimental units. In the literature, a vast number of such designs have been developed. This package generates some efficient neighbour balanced block designs which are balanced and partially variance balanced for estimating the contrast pertaining to direct and neighbour effects, as well as provides a function for analysing the data obtained from such trials (Azais, J.M., Bailey, R.A. and Monod, H. (1993). "A catalogue of efficient neighbour designs with border plots". Biometrics, 49, 1252-1261 ; Tomar, J. S., Jaggi, Seema and Varghese, Cini (2005)<DOI: 10.1080/0266476042000305177>. "On totally balanced block designs for competition effects"). This package contains functions named nbbd1(),nbbd2(),nbbd3(),pnbbd1() and pnbbd2() which generates neighbour balanced block designs within a specified range of number of treatment (v). It contains another function named anlys()for performing the analysis of data generated from such trials.

This package provides a SQLite-backed cell-level cache that can be used as a drop-in backend by the nordstat family of packages ('rKolada', rTrafa', and pixieweb'). Designed for multi-user web applications where minimal fetch latency and asynchronous writes are required. Individual statistical values ("cells") are stored in a gatekeeper schema with a sidecar table for arbitrary metadata dimensions, enabling deduplication across overlapping queries.

Given a failure type, the function computes covariate-specific probability of failure over time and covariate-specific conditional hazard rate based on possibly right-censored competing risk data. Specifically, it computes the non-parametric maximum-likelihood estimates of these quantities and their asymptotic variances in a semi-parametric mixture model for competing-risks data, as described in Chang et al. (2007a).

Fits sphere-sphere regression models by estimating locally weighted rotations. Simulation of sphere-sphere data according to non-rigid rotation models. Provides methods for bias reduction applying iterative procedures within a Newton-Raphson learning scheme. Cross-validation is exploited to select smoothing parameters. See Marco Di Marzio, Agnese Panzera & Charles C. Taylor (2018) <doi:10.1080/01621459.2017.1421542>.

Draw nested extreme value random variables, which are the variables that appear in the latent variable formulation of the nested logit model.

Estimates the relative transmission probabilities between cases in an infectious disease outbreak or cluster using naive Bayes. Included are various functions to use these probabilities to estimate transmission parameters such as the generation/serial interval and reproductive number as well as finding the contribution of covariates to the probabilities and visualizing results. The ideal use is for an infectious disease dataset with metadata on the majority of cases but more informative data such as contact tracing or pathogen whole genome sequencing on only a subset of cases. For a detailed description of the methods see Leavitt et al. (2020) <doi:10.1093/ije/dyaa031>.

An implementation of the National Information Platforms for Nutrition or NiPN's analytic methods for assessing quality of anthropometric datasets that include measurements of weight, height or length, middle upper arm circumference, sex and age. The focus is on anthropometric status but many of the presented methods could be applied to other variables.

This package provides functions complementary to packages nicheROVER and SIBER allowing the user to extract Bayesian estimates from data objects created by the packages nicheROVER and SIBER'. Please see the following publications for detailed methods on nicheROVER and SIBER Hansen et al. (2015) <doi:10.1890/14-0235.1>, Jackson et al. (2011) <do i:10.1111/j.1365-2656.2011.01806.x>, and Layman et al. (2007) <doi:10.1890/0012-9658(2007)88[42:CSIRPF]2.0.CO;2>, respectfully.

Cross-Entropy optimisation of unconstrained deterministic and noisy functions illustrated in Rubinstein and Kroese (2004, ISBN: 978-1-4419-1940-3) through a highly flexible and customisable function which allows user to define custom variable domains, sampling distributions, updating and smoothing rules, and stopping criteria. Several built-in methods and settings make the package very easy-to-use under standard optimisation problems.

Build, compose, stack, sum, and realize feed-forward neural networks as algebraic objects. Implements the calculus and constructive approximations described by Rafi, Padgett, and Nakarmi (2024) <doi:10.48550/arXiv.2402.01058>, Grohs, Hornung, Jentzen, et al. (2023) <doi:10.1007/s10444-022-09970-2>, and Jentzen, Kuckuck, and von Wurstemberger (2023) <doi:10.48550/arXiv.2310.20360>. Includes neural network polynomials, transcendental-function approximations, multidimensional maximum convolution, and vectorized batch realization.

Multiple and generalized nonparametric regression using smoothing spline ANOVA models and generalized additive models, as described in Helwig (2020) <doi:10.4135/9781526421036885885>. Includes support for Gaussian and non-Gaussian responses, smoothers for multiple types of predictors (including random intercepts), interactions between smoothers of mixed types, eight different methods for smoothing parameter selection, and flexible tools for diagnostics, inference, and prediction.

This package provides functions for specifying and fitting nested dichotomy logistic regression models for a multi-category response and methods for summarising and plotting those models. Nested dichotomies are statistically independent, and hence provide an additive decomposition of tests for the overall polytomous response. When the dichotomies make sense substantively, this method can be a simpler alternative to the standard multinomial logistic model which compares response categories to a reference level. See: J. Fox (2016), "Applied Regression Analysis and Generalized Linear Models", 3rd Ed., ISBN 1452205663.

Utilities for unambiguous, neat and legible representation of data (date, time stamp, numbers, percentages and strings) for presentation of analysis , aiming for elegance and consistency. The purpose of this package is to format data, that is better for presentation and any automation jobs that reports numbers.

Addressing crucial research questions often necessitates a small sample size due to factors such as distinctive target populations, rarity of the event under study, time and cost constraints, ethical concerns, or group-level unit of analysis. Many readily available analytic methods, however, do not accommodate small sample sizes, and the choice of the best method can be unclear. The npboottprm package enables the execution of nonparametric bootstrap tests with pooled resampling to help fill this gap. Grounded in the statistical methods for small sample size studies detailed in Dwivedi, Mallawaarachchi, and Alvarado (2017) <doi:10.1002/sim.7263>, the package facilitates a range of statistical tests, encompassing independent t-tests, paired t-tests, and one-way Analysis of Variance (ANOVA) F-tests. The nonparboot() function undertakes essential computations, yielding detailed outputs which include test statistics, effect sizes, confidence intervals, and bootstrap distributions. Further, npboottprm incorporates an interactive shiny web application, nonparboot_app(), offering intuitive, user-friendly data exploration.

Quantifies and removes technical noise from high-throughput sequencing data. Two approaches are used, one based on the count matrix, and one using the alignment BAM files directly. Contains several options for every step of the process, as well as tools to quality check and assess the stability of output.