Calculate common types of tables for weighted survey data. Options include topline and (2-way and 3-way) crosstab tables of categorical or ordinal data as well as summary tables of weighted numeric variables. Optionally, include the margin of error at selected confidence intervals including the design effect. The design effect is calculated as described by Kish (1965) <doi:10.1002/bimj.19680100122> beginning on page 257. Output takes the form of tibbles (simple data frames). This package conveniently handles labelled data, such as that commonly used by Stata and SPSS. Complex survey design is not supported at this time.

Automate pharmacokinetic/pharmacodynamic bioanalytical procedures based on best practices and regulatory recommendations. The package impose regulatory constrains and sanity checking for common bioanalytical procedures. Additionally, PKbioanalysis provides a relational infrastructure for plate management and injection sequence.

This package implements propensity score weighting methods for estimating counterfactual survival functions, marginal hazard ratios, and weighted Kaplan-Meier and cumulative risk curves in observational studies with time-to-event outcomes. Supports binary and multiple treatment groups with inverse probability of treatment weighting (IPW), overlap weighting (OW), and average treatment effect on the treated (ATT). Includes symmetric trimming (Crump extension) for extreme propensity scores. Variance estimation via analytical M-estimation or bootstrap. Methods based on Li et al. (2018) <doi:10.1080/01621459.2016.1260466>, Li & Li (2019) <doi:10.1214/19-AOAS1282>, and Cheng et al. (2022) <doi:10.1093/aje/kwac043>.

This package provides a set of functions for reading and writing PC-Axis files, used by different statistical organizations around the globe for data dissemination.

This package provides functions to implement and simulate the partial order continual reassessment method (PO-CRM) of Wages, Conaway and O'Quigley (2011) <doi:10.1177/1740774511408748> for use in Phase I trials of combinations of agents. Provides a function for generating a set of initial guesses (skeleton) for the toxicity probabilities at each combination that correspond to the set of possible orderings of the toxicity probabilities specified by the user.

This package contains tools for supervised analyses of incomplete, overlapping multiomics datasets. Applies partial least squares in multiple steps to find models that predict survival outcomes. See Yamaguchi et al. (2023) <doi:10.1101/2023.03.10.532096>.

This package provides methods to detect genetic markers involved in biological adaptation. pcadapt provides statistical tools for outlier detection based on Principal Component Analysis. Implements the method described in (Luu, 2016) <DOI:10.1111/1755-0998.12592> and later revised in (Privé, 2020) <DOI:10.1093/molbev/msaa053>.

This package contains model fitting functions for linear and non-linear adsorption kinetic and diffusion models. Adsorption kinetics is used for characterizing the rate of solute adsorption and the time necessary for the adsorption process. Adsorption kinetics offers vital information on adsorption rate, adsorbent performance in response time, and mass transfer processes. In addition, diffusion models are included in the package as solute diffusion affects the adsorption kinetic experiments. This package consists of 20 adsorption and diffusion models, including Pseudo First Order (PFO), Pseudo Second Order (PSO), Elovich, and Weber-Morris model (commonly called the intraparticle model) stated by Plazinski et al. (2009) <doi:10.1016/j.cis.2009.07.009>. This package also contains a summary function where the statistical errors of each model are ranked for a more straightforward determination of the best fit model.

Fits Parametric Frailty Models by maximum marginal likelihood. Possible baseline hazards: exponential, Weibull, inverse Weibull (Fréchet), Gompertz, lognormal, log-skew-normal, and loglogistic. Possible Frailty distributions: gamma, positive stable, inverse Gaussian and lognormal.

Tokenizers break text into pieces that are more usable by machine learning models. Many tokenizers share some preparation steps. This package provides those shared steps, along with a simple tokenizer.

Compute detailed and aggregated performance spectrum for event data. The detailed performance spectrum describes the event data in terms of segments, where the performance of each segment is measured and plotted for any occurrences of this segment over time and can be classified, e.g., regarding the overall population. The aggregated performance spectrum visualises the amount of cases of particular performance over time. Denisov, V., Fahland, D., & van der Aalst, W. M. P. (2018) <doi:10.1007/978-3-319-98648-7_9>.

This package provides a framework for defining pipelines of functions for applying data transformations, model estimation and inverse-transformations, resulting in predicted value generation (or model-scoring) functions that automatically apply the entire pipeline of functions required to go from input to predicted output.

Implementation of assumption-lean and data-adaptive post-prediction inference (POPInf), for valid and efficient statistical inference based on data predicted by machine learning. See Miao, Miao, Wu, Zhao, and Lu (2023) <arXiv:2311.14220>.

Data and utilities for estimating pediatric blood pressure percentiles by sex, age, and optionally height (stature) as described in Martin et al. (2022) <doi:10.1001/jamanetworkopen.2022.36918>. Blood pressure percentiles for children under one year of age come from Gemelli et al. (1990) <doi:10.1007/BF02171556>. Estimates of blood pressure percentiles for children at least one year of age are informed by data from the National Heart, Lung, and Blood Institute (NHLBI) and the Centers for Disease Control and Prevention (CDC) <doi:10.1542/peds.2009-2107C> or from Lo et al. (2013) <doi:10.1542/peds.2012-1292>. The source-selection flowchart comes from Martin et al. (2022) <doi:10.1542/hpeds.2021-005998>.

You can use this program for 3 sets of categorical data for propensity score matching. Assume that the data has 3 different categorical variables. You can use it to perform propensity matching of baseline indicator groupings. The matching will make the differences in the baseline data smaller. This method was described by Alvaro Fuentes (2022) <doi:10.1080/00273171.2021.1925521>.

This package provides a simple interface in the form of R6 classes for executing tasks in parallel, tracking their progress, and displaying accurate progress bars.

Spatial estimation of a prevalence surface or a relative risks surface, using data from a Demographic and Health Survey (DHS) or an analog survey, see Larmarange et al. (2011) <doi:10.4000/cybergeo.24606>.

This package contains logic for computing the statistical association of variable groups, i.e., gene sets, with respect to the principal components of genomic data.

Allows users to derive multi-objective weights from pairwise comparisons, which research shows is more repeatable, transparent, and intuitive other techniques. These weights can be rank existing alternatives or to define a multi-objective utility function for optimization.

Estimation of panel models for glm-like models: this includes binomial models (logit and probit), count models (poisson and negbin) and ordered models (logit and probit), as described in: Baltagi (2013) Econometric Analysis of Panel Data, ISBN-13:978-1-118-67232-7, Hsiao (2014) Analysis of Panel Data <doi:10.1017/CBO9781139839327> and Croissant and Millo (2018), Panel Data Econometrics with R, ISBN:978-1-118-94918-4.

Allows the user to perform ANOVA tests (in a strict sense: continuous and normally-distributed Y variable and 1 or more factorial/categorical X variable(s)), with the possibility to specify the type of sum of squares (1, 2 or 3), the types of variables (Fixed or Random) and their relationships (crossed or nested) with the sole function of the package (FullyParamANOVA()). The resulting outputs are the same as in SAS software. A dataset (Butterfly) to test the function is also joined.

This package provides the probability, distribution, and quantile functions and random number generator for the Poisson-Binomial distribution. This package relies on FFTW to implement the discrete Fourier transform, so that it is much faster than the existing implementation of the same algorithm in R.

This package provides functions for computing fit indices for evaluating the path component of latent variable structural equation models. Available fit indices include RMSEA-P and NSCI-P originally presented and evaluated by Williams and O'Boyle (2011) <doi:10.1177/1094428110391472> and demonstrated by O'Boyle and Williams (2011) <doi:10.1037/a0020539> and Williams, O'Boyle, & Yu (2020) <doi:10.1177/1094428117736137>. Also included are fit indices described by Hancock and Mueller (2011) <doi:10.1177/0013164410384856>.

Simulation of continuous, correlated high-dimensional data with time to event or binary response, and parallelized functions for Lasso, Ridge, and Elastic Net penalized regression with repeated starts and two-dimensional tuning of the Elastic Net.