Updating the now 10-year-old nycflights13 data package. It contains information about all flights that departed from the three main New York City airports in 2023 and metadata on airlines, airports, weather, and planes.

Designed for association studies in nested association mapping (NAM) panels, experimental and random panels. The method is described by Xavier et al. (2015) <doi:10.1093/bioinformatics/btv448>. It includes tools for genome-wide associations of multiple populations, marker quality control, population genetics analysis, genome-wide prediction, solving mixed models and finding variance components through likelihood and Bayesian methods.

This package provides a client for the open-source monitoring and alerting toolkit, Prometheus', that emits metrics in the OpenMetrics format. Allows users to automatically instrument Plumber and Shiny applications, collect standard process metrics, as well as define custom counter, gauge, and histogram metrics of their own.

This package provides a collection of general-purpose helper functions that I (and maybe others) find useful when developing data science software. Includes tools for simulation, data transformation, input validation, and more.

Interact seamlessly with Open Target GraphQL endpoint to query and retrieve tidy data tables, facilitating the analysis of gene, disease, drug, and genetic data. For more information about the Open Target API (<https://platform.opentargets.org/api>).

Automated reporting in Word and PowerPoint can require customization for each organizational template. This package works around this by adding standard reporting functions and an abstraction layer to facilitate automated reporting workflows that can be replicated across different organizational templates.

Generates prediction intervals and orchard plots for meta-analytic and meta-regression models fitted with the metafor package. Orchard plots augment classic forest plots by displaying individual effect sizes together with group means and their confidence and prediction intervals, providing an enhanced visualization of meta-analytic data for ecology, evolution, and beyond. Methods are described in Nakagawa et al. (2023) <doi:10.1111/2041-210X.14152>.

The classical and extended occupancy distributions occur in cases where balls are randomly allocated to bins. The PDF, CDF, quantile functions, generation of random variates, and calculating the first four central moments of the distributions are implemented as described in Oâ Neill (2019) <doi:10.1080/00031305.2019.1699445>.

This package implements the algorithm in Chen, Wang and Samworth (2020) <arxiv:2003.03668> for online detection of sudden mean changes in a sequence of high-dimensional observations. It also implements methods by Mei (2010) <doi:10.1093/biomet/asq010>, Xie and Siegmund (2013) <doi:10.1214/13-AOS1094> and Chan (2017) <doi:10.1214/17-AOS1546>.

Order-of-addition experiments are often conducted to address research questions in many real-world studies. This package provides a comprehensive toolbox for researchers and practitioners to design and analyze order-of-addition experiments. Detailed comparisons and summary of all statistical methods in this package can be found in Tsai (2026), "Order-of-addition experiments in R using OofAExp", Journal of Quality Technology (to appear).

This package provides a novel method to implement cancer subtyping and subtype specific drug targets identification via non-negative matrix tri-factorization. To improve the interpretability, we introduce orthogonal constraint to the row coefficient matrix and column coefficient matrix. To meet the prior knowledge that each subtype should be strongly associated with few gene sets, we introduce sparsity constraint to the association sub-matrix. The average residue was introduced to evaluate the row and column cluster numbers. This is part of the work "Liver Cancer Analysis via Orthogonal Sparse Non-Negative Matrix Tri- Factorization" which will be submitted to BBRC.

Supports the analysis of Oceanographic data, including ADCP measurements, measurements made with argo floats, CTD measurements, sectional data, sea-level time series, coastline and topographic data, etc. Provides specialized functions for calculating seawater properties such as potential temperature in either the UNESCO or TEOS-10 equation of state. Produces graphical displays that conform to the conventions of the Oceanographic literature. This package is discussed extensively by Kelley (2018) "Oceanographic Analysis with R" <doi:10.1007/978-1-4939-8844-0>.

Standardized survey outcome rate functions, including the response rate, contact rate, cooperation rate, and refusal rate. These outcome rates allow survey researchers to measure the quality of survey data using definitions published by the American Association for Public Opinion Research (AAPOR). For details on these standards, see AAPOR (2023) <https://aapor.org/wp-content/uploads/2024/03/Standards-Definitions-10th-edition.pdf>.

Aids practitioners to optimally design experiments that measure the slope divided by the intercept and provides confidence intervals for the ratio.

This package provides functionalities and data structures to retrieve, analyze and visualize aviation data. It includes a client interface to the OpenSky API <https://opensky-network.org>. It allows retrieval of flight information, as well as aircraft state vectors.

Calculates ordinated diet breadth with some plotting functions.

An unofficial wrapper for okx exchange v5 API <https://www.okx.com/docs-v5/en/>, including REST API and WebSocket API.

Bayesian reconstruction of who infected whom during past outbreaks using routinely-collected surveillance data. Inference of transmission trees using genotype, age specific social contacts, distance between cases and onset dates of the reported cases. (Robert A, Kucharski AJ, Gastanaduy PA, Paul P, Funk S. (2020) <doi:10.1098/rsif.2020.0084>).

We consider the problem of estimating two isotonic regression curves g1* and g2* under the constraint that they are ordered, i.e. g1* <= g2*. Given two sets of n data points y_1, ..., y_n and z_1, ..., z_n that are observed at (the same) deterministic design points x_1, ..., x_n, the estimates are obtained by minimizing the Least Squares criterion L(a, b) = sum_i=1^n (y_i - a_i)^2 w1(x_i) + sum_i=1^n (z_i - b_i)^2 w2(x_i) over the class of pairs of vectors (a, b) such that a and b are isotonic and a_i <= b_i for all i = 1, ..., n. We offer two different approaches to compute the estimates: a projected subgradient algorithm where the projection is calculated using a PAVA as well as Dykstra's cyclical projection algorithm.

This package provides a random forest based implementation of the method described in Chapter 7.1.2 (Regression model based anomaly detection) of Chandola et al. (2009) <doi:10.1145/1541880.1541882>. It works as follows: Each numeric variable is regressed onto all other variables by a random forest. If the scaled absolute difference between observed value and out-of-bag prediction of the corresponding random forest is suspiciously large, then a value is considered an outlier. The package offers different options to replace such outliers, e.g. by realistic values found via predictive mean matching. Once the method is trained on a reference data, it can be applied to new data.

The olr function systematically evaluates multiple linear regression models by exhaustively fitting all possible combinations of independent variables against the specified dependent variable. It selects the model that yields the highest adjusted R-squared (by default) or R-squared, depending on user preference. In model evaluation, both R-squared and adjusted R-squared are key metrics: R-squared measures the proportion of variance explained but tends to increase with the addition of predictorsâ regardless of relevanceâ potentially leading to overfitting. Adjusted R-squared compensates for this by penalizing model complexity, providing a more balanced view of fit quality. The goal of olr is to identify the most suitable model that captures the underlying structure of the data while avoiding unnecessary complexity. By comparing both metrics, it offers a robust evaluation framework that balances predictive power with model parsimony. Example Analogy: Imagine a gardener trying to understand what influences plant growth (the dependent variable). They might consider variables like sunlight, watering frequency, soil type, and nutrients (independent variables). Instead of manually guessing which combination works best, the olr function automatically tests every possible combination of predictors and identifies the most effective modelâ based on either the highest R-squared or adjusted R-squared value. This saves the user from trial-and-error modeling and highlights only the most meaningful variables for explaining the outcome. A Python version is also available at <https://pypi.org/project/olr>.

This package provides a database management tool built as a shiny application. Connect to various databases to send queries, upload files, preview tables, and more.

Tests the observed overlapping polygon area in a collection of polygons against a null model of random rotation, as explained in De la Cruz et al. (2017) <doi:10.13140/RG.2.2.12825.72801>.

Multiple tools are now available for inferring the personalised germ line set from an adaptive immune receptor repertoire. Output from these tools is converted to a single format and supplemented with rich data such as usage and characterisation of novel germ line alleles. This data can be particularly useful when considering the validity of novel inferences. Use of the analysis provided is described in <doi:10.3389/fimmu.2019.00435>.