Automate pharmacokinetic/pharmacodynamic bioanalytical procedures based on best practices and regulatory recommendations. The package impose regulatory constrains and sanity checking for common bioanalytical procedures. Additionally, PKbioanalysis provides a relational infrastructure for plate management and injection sequence.

Read and write GraphPad Prism .pzfx files in R.

This provides utilities for creating classed error and warning conditions based on where the error originated.

This package provides a comprehensive implementation of Petersen-type estimators and its many variants for two-sample capture-recapture studies. A conditional likelihood approach is used that allows for tag loss; non reporting of tags; reward tags; categorical, geographical and temporal stratification; partial stratification; reverse capture-recapture; and continuous variables in modeling the probability of capture. Many examples from fisheries management are presented.

Nonparametric density estimation for (hyper)spherical data by means of a parametrically guided kernel estimator (Alonso-Pena et al. (2024) <doi:10.1111/sjos.12737>. The package also allows the data-driven selection of the smoothing parameter and the representation of the estimated density for circular and spherical data. Estimators of the density without guide can also be obtained.

This package provides functions to select samples using PPS (probability proportional to size) sampling. The package also includes a function for stratified simple random sampling, a function to compute joint inclusion probabilities for Sampford's method of PPS sampling, and a few utility functions. The user's guide pps-ug.pdf is included in the .../pps/doc directory. The methods are described in standard survey sampling theory books such as Cochran's "Sampling Techniques"; see the user's guide for references.

This package provides tools to sort, edit and prune pedigrees and to extract the inbreeding coefficients and the relationship matrix (includes code for pedigrees from self-pollinated species). The use of pedigree data is central to genetics research within the animal and plant breeding communities to predict breeding values. The relationship matrix between the individuals can be derived from pedigree structure ('Vazquez et al., 2010') <doi:10.2527/jas.2009-1952>.

This package provides functions that facilitate the elaboration of population pyramids.

In short, this package is a locator for cool, refreshing beverages. It will find and return the nearest location where you can get a cold one.

Set the R prompt dynamically, from a function. The package contains some examples to include various useful dynamic information in the prompt: the status of the last command (success or failure); the amount of memory allocated by the current R process; the name of the R package(s) loaded by pkgload and/or devtools'; various git information: the name of the active branch, whether it is dirty, if it needs pushes pulls. You can also create your own prompt if you don't like the predefined examples.

Implementation of the Pearson distribution system, including full support for the (d,p,q,r)-family of functions for probability distributions and fitting via method of moments and maximum likelihood method.

This package provides data set and function for exploration of Multiple Indicator Cluster Survey (MICS) 2017-18 Maternal Mortality questionnaire data for Punjab, Pakistan. The results of the present survey are critically important for the purposes of Sustainable Development Goals (SDGs) monitoring, as the survey produces information on 32 global Sustainable Development Goals (SDGs) indicators. The data was collected from 53,840 households selected at the second stage with systematic random sampling out of a sample of 2,692 clusters selected using probability proportional to size sampling. Six questionnaires were used in the survey: (1) a household questionnaire to collect basic demographic information on all de jure household members (usual residents), the household, and the dwelling; (2) a water quality testing questionnaire administered in three households in each cluster of the sample; (3) a questionnaire for individual women administered in each household to all women age 15-49 years; (4) a questionnaire for individual men administered in every second household to all men age 15-49 years; (5) an under-5 questionnaire, administered to mothers (or caretakers) of all children under 5 living in the household; and (6) a questionnaire for children age 5-17 years, administered to the mother (or caretaker) of one randomly selected child age 5-17 years living in the household (<http://www.mics.unicef.org/surveys>).

Pool dilution is a isotope tracer technique wherein a biogeochemical pool is artifically enriched with its heavy isotopologue and the gross productive and consumptive fluxes of that pool are quantified by the change in pool size and isotopic composition over time. This package calculates gross production and consumption rates from closed-system isotopic pool dilution time series data. Pool size concentrations and heavy isotope (e.g., 15N) content are measured over time and the model optimizes production rate (P) and the first order rate constant (k) by minimizing error in the model-predicted total pool size, as well as the isotopic signature. The model optimizes rates by weighting information against the signal:noise ratio of concentration and heavy- isotope signatures using measurement precision as well as the magnitude of change over time. The calculations used here are based on von Fischer and Hedin (2002) <doi:10.1029/2001GB001448> with some modifications.

Perform tests for pleiotropy of multiple traits of various variable types on genotypes for a genetic marker.

Fill missing symmetrical data with mirroring, calculate Procrustes alignments with or without scaling, and compute standard or vector correlation and covariance matrices (congruence coefficients) of 3D landmarks. Tolerates missing data for all analyses.

The Piece-wise exponential (Additive Mixed) Model (PAMM; Bender and others (2018) <doi: 10.1177/1471082X17748083>) is a powerful model class for the analysis of survival (or time-to-event) data, based on Generalized Additive (Mixed) Models (GA(M)Ms). It offers intuitive specification and robust estimation of complex survival models with stratified baseline hazards, random effects, time-varying effects, time-dependent covariates and cumulative effects (Bender and others (2019)), as well as support for left-truncated data as well as competing risks, recurrent events and multi-state settings. pammtools provides tidy workflow for survival analysis with PAMMs, including data simulation, transformation and other functions for data preprocessing and model post-processing as well as visualization.

This package provides tools for both single and batch image manipulation and analysis (Olivoto, 2022 <doi:10.1111/2041-210X.13803>) and phytopathometry (Olivoto et al., 2022 <doi:10.1007/S40858-021-00487-5>). The tools can be used for the quantification of leaf area, object counting, extraction of image indexes, shape measurement, object landmark identification, and Elliptical Fourier Analysis of object outlines (Claude (2008) <doi:10.1007/978-0-387-77789-4>). The package also provides a comprehensive pipeline for generating shapefiles with complex layouts and supports high-throughput phenotyping of RGB, multispectral, and hyperspectral orthomosaics. This functionality facilitates field phenotyping using UAV- or satellite-based imagery.

The perturbR() function incrementally perturbs network edges (using the rewireR function)and compares the resulting community detection solutions from the rewired networks with the solution found for the original network. These comparisons aid in understanding the stability of the original solution. The package requires symmetric, weighted (specifically, count) matrices/networks.

The calculation of p-variation of the finite sample data. This package is a realisation of the procedure described in Butkus, V. & Norvaisa, R. Lith Math J (2018). <doi: 10.1007/s10986-018-9414-3> The formal definitions and reference into literature are given in vignette.

R Interface to Pullword Service for natural language processing in Chinese. It enables users to extract valuable words from text by deep learning models. For more details please visit the official site (in Chinese) <http://www.pullword.com/>.

Easily visualize and animate tabledap and griddap objects obtained via the rerddap package in a simple one-line command, using either base graphics or ggplot2 graphics. plotdap handles extracting and reshaping the data, map projections and continental outlines. Optionally the data can be animated through time using the gganmiate package.

Pattern Sequence Based Forecasting (PSF) takes univariate time series data as input and assist to forecast its future values. This algorithm forecasts the behavior of time series based on similarity of pattern sequences. Initially, clustering is done with the labeling of samples from database. The labels associated with samples are then used for forecasting the future behaviour of time series data. The further technical details and references regarding PSF are discussed in Vignette.

This package provides a standardized framework to support the selection and evaluation of parametric survival models for time-to-event data. Includes tools for visualizing survival data, checking proportional hazards assumptions (Grambsch and Therneau, 1994, <doi:10.1093/biomet/81.3.515>), comparing parametric (Ishak and colleagues, 2013, <doi:10.1007/s40273-013-0064-3>), spline (Royston and Parmar, 2002, <doi:10.1002/sim.1203>) and cure models, examining hazard functions, and evaluating model extrapolation. Methods are consistent with recommendations in the NICE Decision Support Unit Technical Support Documents (14 and 21 <https://sheffield.ac.uk/nice-dsu/tsds/survival-analysis>). Results are structured to facilitate integration into decision-analytic models, and reports can be generated with rmarkdown'. The package builds on existing tools including flexsurv (Jackson, 2016, <doi:10.18637/jss.v070.i08>)) and flexsurvcure for estimating cure models.

This package provides functions which facilitate harmonization of data from multiple different datasets. Data harmonization involves taking data sources with differing values, creating coding instructions to create a harmonized set of values, then making those data modifications. psHarmonize will assist with data modification once the harmonization instructions are written. Coding instructions are written by the user to create a "harmonization sheet". This sheet catalogs variable names, domains (e.g. clinical, behavioral, outcomes), provides R code instructions for mapping or conversion of data, specifies the variable name in the harmonized data set, and tracks notes. The package will then harmonize the source datasets according to the harmonization sheet to create a harmonized dataset. Once harmonization is finished, the package also has functions that will create descriptive statistics using RMarkdown'. Data Harmonization guidelines have been described by Fortier I, Raina P, Van den Heuvel ER, et al. (2017) <doi:10.1093/ije/dyw075>. Additional details of our R package have been described by Stephen JJ, Carolan P, Krefman AE, et al. (2024) <doi:10.1016/j.patter.2024.101003>.