Returns almost all features that has been extracted from Position Specific Scoring Matrix (PSSM) so far, which is a matrix of L rows (L is protein length) and 20 columns produced by PSI-BLAST which is a program to produce PSSM Matrix from multiple sequence alignment of proteins see <https://www.ncbi.nlm.nih.gov/books/NBK2590/> for mor details. some of these features are described in Zahiri, J., et al.(2013) <DOI:10.1016/j.ygeno.2013.05.006>, Saini, H., et al.(2016) <DOI:10.17706/jsw.11.8.756-767>, Ding, S., et al.(2014) <DOI:10.1016/j.biochi.2013.09.013>, Cheng, C.W., et al.(2008) <DOI:10.1186/1471-2105-9-S12-S6>, Juan, E.Y., et al.(2009) <DOI:10.1109/CISIS.2009.194>.

This package provides tools for analyzing data generated from conjoint survey experiments, a method widely used in the social sciences for studying multidimensional preferences. The package implements estimation of marginal means (MMs) and average marginal component effects (AMCEs), with corrections for measurement error. Methods include profile-level and choice-level estimators, bias correction using intra-respondent reliability (IRR), and visualization utilities. For details on the methodology, see Clayton, Horiuchi, Kaufman, King, and Komisarchik (2025) <https://gking.harvard.edu/conjointE>.

Pedigree related functions.

This package implements the American Heart Association Predicting Risk of cardiovascular disease EVENTs (PREVENT) equations from Khan SS, Matsushita K, Sang Y, and colleagues (2023) <doi:10.1161/CIRCULATIONAHA.123.067626>, with optional comparison with their de facto predecessor, the Pooled Cohort Equations from the American Heart Association and American College of Cardiology (2013) <doi:10.1161/01.cir.0000437741.48606.98> and the revision to the Pooled Cohort Equations from Yadlowsky and colleagues (2018) <doi:10.7326/M17-3011>.

This package implements the methods for assessing heterogeneous cluster-specific treatment effects in partially nested designs as described in Liu (2024) <doi:10.1037/met0000723>. The estimation uses the multiply robust method, allowing for the use of machine learning methods in model estimation (e.g., random forest, neural network, and the super learner ensemble). Partially nested designs (also known as partially clustered designs) are designs where individuals in the treatment arm are assigned to clusters (e.g., teachers, tutoring groups, therapists), whereas individuals in the control arm have no such clustering.

Quickly and easily add a mini map to your rmarkdown html documents.

Computes probability-scale residuals and residual correlations for continuous, ordinal, binary, count, and time-to-event data Qi Liu, Bryan Shepherd, Chun Li (2020) <doi:10.18637/jss.v094.i12>.

Interactively explore various dependencies of a package(s) (on the Comprehensive R Archive Network Like repositories) and perform analysis using tidy philosophy. Most of the functions return a tibble object (enhancement of dataframe') which can be used for further analysis. The package offers functions to produce network and igraph dependency graphs. The plot method produces a static plot based on ggnetwork and plotd3 function produces an interactive D3 plot based on networkD3'.

The package solves linear system of equations Ax=b by using Preconditioned Conjugate Gradient Algorithm where A is real symmetric positive definite matrix. A suitable preconditioner matrix may be provided by user. This can also be used to minimize quadratic function (x'Ax)/2-bx for unknown x.

Conduct dsep tests (piecewise SEM) of a directed, or mixed, acyclic graph without latent variables (but possibly with implicitly marginalized or conditioned latent variables that create dependent errors) based on linear, generalized linear, or additive modelswith or without a nesting structure for the data. Also included are functions to do desp tests step-by-step,exploratory path analysis, and Monte Carlo X2 probabilities. This package accompanies Shipley, B, (2026).Cause and Correlation in Biology: A User's Guide to Path Analysis, StructuralEquations and Causal Inference (3rd edition). Cambridge University Press.

Enables direct cloud access to health care decision models hosted on the PRISM server of the Peer Models Network.

Penalized orthogonal-components regression (POCRE) is a supervised dimension reduction method for high-dimensional data. It sequentially constructs orthogonal components (with selected features) which are maximally correlated to the response residuals. POCRE can also construct common components for multiple responses and thus build up latent-variable models.

R functions to access provenance information collected by rdt or rdtLite'. The information is stored inside a ProvInfo object and can be accessed through a collection of functions that will return the requested data. The exact format of the JSON created by rdt and rdtLite is described in <https://github.com/End-to-end-provenance/ExtendedProvJson>.

This package implements an extension of the Chacko chi-square test for ordered vectors (Chacko, 1966, <https://www.jstor.org/stable/25051572>). Our extension brings the Chacko test to the computer age by implementing a permutation test to offer a numeric estimate of the p-value, which is particularly useful when the analytic solution is not available.

This package provides a set of tools to install, manage and run several Pandoc versions.

This package provides a C++ backend for multivariate phylogenetic comparative models implemented in the R-package PCMBase'. Can be used in combination with PCMBase to enable fast and parallel likelihood calculation. Implements the pruning likelihood calculation algorithm described in Mitov et al. (2020) <doi:10.1016/j.tpb.2019.11.005>. Uses the SPLITT C++ library for parallel tree traversal described in Mitov and Stadler (2018) <doi:10.1111/2041-210X.13136>.

This package provides a comprehensive and curated collection of datasets related to the lungs, respiratory system, and associated diseases. This package includes epidemiological, clinical, experimental, and simulated datasets on conditions such as lung cancer, asthma, Chronic Obstructive Pulmonary Disease (COPD), tuberculosis, whooping cough, pneumonia, influenza, and other respiratory illnesses. It is designed to support data exploration, statistical modeling, teaching, and research in pulmonary medicine, public health, environmental epidemiology, and respiratory disease surveillance.

This package provides functions for bootstrapping the power of ANOVA designs based on estimated means and standard deviations of the conditions. Please refer to the documentation of the boot.power.anova() function for further details.

An implementation of the one-step privacy-protecting method for estimating the overall and site-specific hazard ratios using inverse probability weighted Cox models in distributed data network studies, as proposed by Shu, Yoshida, Fireman, and Toh (2019) <doi: 10.1177/0962280219869742>. This method only requires sharing of summary-level riskset tables instead of individual-level data. Both the conventional inverse probability weights and the stabilized weights are implemented.

Kernel density estimation with global bandwidth selection via "plug-in".

This package provides a secure and user-friendly interface to interact with the Plug <https://plugbytpf.com.br> API'. It enables developers to store and manage tokens securely using the keyring package, retrieve data from API endpoints with the httr2 package, and handle large datasets with chunked data fetching. Designed for simplicity and security, the package facilitates seamless integration with Plug ecosystem.

This package provides functions for generating variants of curves: restricted cubic spline, periodic restricted cubic spline, periodic cubic spline. Periodic splines can be used to model data that has periodic nature / seasonality.

Access the data of the Catalogue of the Timber Forest Species of the Peruvian Amazon Vásquez Martà nez, R., & Rojas Gonzáles, R.D.P.(2022)<doi:10.21704/rfp.v37i3.1956>.

Executes simple parametric models for right-censored survival data. Functionality emulates capabilities in Minitab', including fitting right-censored data, assessing fit, plotting survival functions, and summary statistics and probabilities.