Estimation of pharmacokinetic parameters using non-compartmental theory.

Pivot easily by specifying rows, columns, values and split.

This package provides an interface to the GenderAPI.io Phone Number Validation & Formatter API (<https://www.genderapi.io>) for validating international phone numbers, detecting number type (mobile, landline, Voice over Internet Protocol (VoIP)), retrieving region and country metadata, and formatting numbers to E.164 or national format. Designed to simplify integration into R workflows for data validation, Customer Relationship Management (CRM) data cleaning, and analytics tasks. Full documentation is available at <https://www.genderapi.io/docs-phone-validation-formatter-api>.

Calculating Pst values to assess differentiation among populations from a set of quantitative traits is the primary purpose of such a package. The bootstrap method provides confidence intervals and distribution histograms of Pst. Variations of Pst in function of the parameter c/h^2 are studied as well. Finally, the package proposes different transformations especially to eliminate any variation resulting from allometric growth (calculation of residuals from linear regressions, Reist standardizations or Aitchison transformation).

This package provides a high performance package implementing random effects and/or sample selection models for panel count data. The details of the models are discussed in Peng and Van den Bulte (2023) <doi:10.2139/ssrn.2702053>.

This package provides tools for calculating statistical power for experiments analyzed using linear mixed models. It supports standard designs, including randomized block, split-plot, and Latin Square designs, while offering flexibility to accommodate a variety of other complex study designs.

Construct and analyze projection matrix models from a demography study of marked individuals classified by age or stage. The package covers methods described in Matrix Population Models by Caswell (2001) and Quantitative Conservation Biology by Morris and Doak (2002).

This package provides tools for exploring projection pursuit classification tree using various projection pursuit indexes.

Interface to Phylocom (<https://phylodiversity.net/phylocom/>), a library for analysis of phylogenetic community structure and character evolution. Includes low level methods for interacting with the three executables, as well as higher level interfaces for methods like aot', ecovolve', bladj', phylomatic', and more.

In gene sequencing methods, the topological features of protein-protein interaction (PPI) networks are often used, such as ToppNet <https://toppgene.cchmc.org>. In this study, a candidate gene prioritization method was proposed for non-communicable diseases considering disease risks transferred between genes in weighted disease PPI networks with weights for nodes and edges based on functional information.

Tailoring the optimal biomarker(s) for disease screening or diagnosis based on subjects individual characteristics.

Simulate dose regimens for pharmacokinetic-pharmacodynamic (PK-PD) models described by differential equation (DE) systems. Simulation using ADVAN-style analytical equations is also supported (Abuhelwa et al. (2015) <doi:10.1016/j.vascn.2015.03.004>).

Read, process, fit, and analyze photosynthetic gas exchange measurements. Documentation is provided by several vignettes; also see Lochocki, Salesse-Smith, & McGrath (2025) <doi:10.1111/pce.15501>.

Bayesian network learning using the PCHC, FEDHC, MMHC and variants of these algorithms. PCHC stands for PC Hill-Climbing, a new hybrid algorithm that uses PC to construct the skeleton of the BN and then applies the Hill-Climbing greedy search. More algorithms and variants have been added, such as MMHC, FEDHC, and the Tabu search variants, PCTABU, MMTABU and FEDTABU. The relevant papers are: a) Tsagris M. (2021). "A new scalable Bayesian network learning algorithm with applications to economics". Computational Economics, 57(1): 341-367. <doi:10.1007/s10614-020-10065-7>. b) Tsagris M. (2022). "The FEDHC Bayesian Network Learning Algorithm". Mathematics 2022, 10(15): 2604. <doi:10.3390/math10152604>.

This package provides functions for solving systems of delay differential equations by interfacing with numerical routines written by Simon N. Wood, including contributions from Benjamin J. Cairns. These numerical routines first appeared in Simon Wood's solv95 program. This package includes a vignette and a complete user's guide. PBSddesolve originally appeared on CRAN under the name ddesolve'. That version is no longer supported. The current name emphasizes a close association with other PBS packages, particularly PBSmodelling'.

This package provides tools for analyzing Pakistan's Population Censuses data via the PakPC2023 and PakPC2017 R packages. Designed for researchers, policymakers, and professionals, the app enables in-depth numerical and graphical analysis, including detailed cross-tabulations and insights. With diverse statistical models and visualization options, it supports informed decision-making in social and economic policy. This tool enhances users ability to explore and interpret census data, providing valuable insights for effective planning and analysis across various fields.

Analysis of pervasiveness of effects in correlational data. The Observed Proportion (or Percentage) of Concordant Pairs (OPCP) is Kendall's Tau expressed on a 0 to 1 metric instead of the traditional -1 to 1 metric to facilitate interpretation. As its name implies, it represents the proportion of concordant pairs in a sample (with an adjustment for ties). Pairs are concordant when a participant who has a larger value on a variable than another participant also has a larger value on a second variable. The OPCP is therefore an easily interpretable indicator of monotonicity. The pervasive functions are essentially wrappers for the arules package by Hahsler et al. (2025)<doi:10.32614/CRAN.package.arules> and serve to count individuals who actually display the pattern(s) suggested by a regression. For more details, see the paper "Considering approaches to pervasiveness in the context of personality psychology" now accepted at the journal Personality Science.

This package performs genomic prediction of hybrid performance using eight statistical methods including GBLUP, BayesB, RKHS, PLS, LASSO, EN, LightGBM and XGBoost along with additive and additive-dominance models. Users are able to incorporate parental phenotypic information in all methods based on their specific needs. (Xu S et al(2017) <doi:10.1534/g3.116.038059>; Xu Y et al (2021) <doi: 10.1111/pbi.13458>).

Generation of count (assuming Poisson distribution) and continuous data (using Fleishman polynomials) simultaneously. The details of the method are explained in Demirtas et al. (2012) <DOI:10.1002/sim.5362>.

Automatically create a webserver from annotated R files or by building it up programmatically. Provides automatic OpenAPI documentation, input handling, async support, and middleware support.

Implementations of algorithms from Learning Sparse Penalties for Change-point Detection using Max Margin Interval Regression, by Hocking, Rigaill, Vert, Bach <http://proceedings.mlr.press/v28/hocking13.html> published in proceedings of ICML2013.

Streamline the creation of Docker images with R packages and dependencies embedded. The pracpac package provides a usethis'-like interface to creating Dockerfiles with dependencies managed by renv'. The pracpac functionality is described in Nagraj and Turner (2023) <doi:10.48550/arXiv.2303.07876>.

Generation of multiple count, binary, ordinal and normal variables simultaneously given the marginal characteristics and association structure. The details of the method are explained in Demirtas et al. (2012) <DOI:10.1002/sim.5362>.

Determine the chlorophyll a (Chl a) concentrations of different phytoplankton groups based on their pigment biomarkers. The method uses non-negative matrix factorisation and simulated annealing to minimise error between the observed and estimated values of pigment concentrations (Hayward et al. (2023) <doi:10.1002/lom3.10541>). The approach is similar to the widely used CHEMTAX program (Mackey et al. 1996) <doi:10.3354/meps144265>, but is more straightforward, accurate, and not reliant on initial guesses for the pigment to Chl a ratios for phytoplankton groups.