This package provides tools to show and draw image pixels using HTML widgets and Shiny applications. It can be used to visualize the MNIST dataset for handwritten digit recognition or to create new image recognition datasets.

This R package provides power calculations via internal simulation methods. The package also provides a frontend to the now abandoned PBAT program (developed by Christoph Lange), and reads in the corresponding output and displays results and figures when appropriate. The license of this R package itself is GPL. However, to have the program interact with the PBAT program for some functionality of the R package, users must additionally obtain the PBAT program from Christoph Lange, and accept his license. Both the data analysis and power calculations have command line and graphical interfaces using tcltk.

Generation of multiple count, binary and ordinal variables simultaneously given the marginal characteristics and association structure. Throughout the package, the word Poisson is used to imply count data under the assumption of Poisson distribution. The details of the method are explained in Amatya, A. and Demirtas, H. (2015) <DOI:10.1080/00949655.2014.953534>.

The constructs used to study the human psychology have many definitions and corresponding instructions for eliciting and coding qualitative data pertaining to constructs content and for measuring the constructs. This plethora of definitions and instructions necessitates unequivocal reference to specific definitions and instructions in empirical and secondary research. This package implements a human- and machine-readable standard for specifying construct definitions and instructions for measurement and qualitative research based on YAML'. This standard facilitates systematic unequivocal reference to specific construct definitions and corresponding instructions in a decentralized manner (i.e. without requiring central curation; Peters (2020) <doi:10.31234/osf.io/xebhn>).

Carries out model-based clustering or classification using parsimonious Gaussian mixture models. McNicholas and Murphy (2008) <doi:10.1007/s11222-008-9056-0>, McNicholas (2010) <doi:10.1016/j.jspi.2009.11.006>, McNicholas and Murphy (2010) <doi:10.1093/bioinformatics/btq498>, McNicholas et al. (2010) <doi:10.1016/j.csda.2009.02.011>.

This package provides functionality for Bayesian analysis of replication studies using power prior approaches (Pawel et al., 2023) <doi:10.1007/s11749-023-00888-5>.

Automates the process of creating a scale bar and north arrow in any package that uses base graphics to plot in R. Bounding box tools help find and manipulate extents. Finally, there is a function to automate the process of setting margins, plotting the map, scale bar, and north arrow, and resetting graphic parameters upon completion.

Small self-contained plots for use in larger plots or to delegate plotting in other functions. Also contains a number of alternative color palettes and HSL color space based tools to modify colors or palettes.

This package performs Bayesian arm-based network meta-analysis for datasets with binary, continuous, and count outcomes (Zhang et al., 2014 <doi:10.1177/1740774513498322>; Lin et al., 2017 <doi:10.18637/jss.v080.i05>).

Allow to run pylint on Python files with a R command or a RStudio addin. The report appears in the RStudio viewer pane as a formatted HTML file.

This package contains utilities for the analysis of post-translational modifications (PTMs) in proteins, with particular emphasis on the sulfoxidation of methionine residues. Features include the ability to download, filter and analyze data from the sulfoxidation database MetOSite'. Utilities to search and characterize S-aromatic motifs in proteins are also provided. In addition, functions to analyze sequence environments around modifiable residues in proteins can be found. For instance, ptm allows to search for amino acids either overrepresented or avoided around the modifiable residues from the proteins of interest. Functions tailored to test statistical hypothesis related to these differential sequence environments are also implemented. Further and detailed information regarding the methods in this package can be found in (Aledo (2020) <https://metositeptm.com>).

Fits the Piecewise Exponential distribution with random time grids using the clustering structure of the Product Partition Models. Details of the implemented model can be found in Demarqui et al. (2008) <doi:10.1007/s10985-008-9086-0>.

This package provides data set and function for exploration of Multiple Indicator Cluster Survey (MICS) 2017-18 Household questionnaire data for Punjab, Pakistan. The results of the present survey are critically important for the purposes of Sustainable Development Goals (SDGs) monitoring, as the survey produces information on 32 global Sustainable Development Goals (SDGs) indicators. The data was collected from 53,840 households selected at the second stage with systematic random sampling out of a sample of 2,692 clusters selected using probability proportional to size sampling. Six questionnaires were used in the survey: (1) a household questionnaire to collect basic demographic information on all de jure household members (usual residents), the household, and the dwelling; (2) a water quality testing questionnaire administered in three households in each cluster of the sample; (3) a questionnaire for individual women administered in each household to all women age 15-49 years; (4) a questionnaire for individual men administered in every second household to all men age 15-49 years; (5) an under-5 questionnaire, administered to mothers (or caretakers) of all children under 5 living in the household; and (6) a questionnaire for children age 5-17 years, administered to the mother (or caretaker) of one randomly selected child age 5-17 years living in the household (<http://www.mics.unicef.org/surveys>).

This package provides a common problem faced by journal reviewers and authors is the question of whether the results of a replication study are consistent with the original published study. One solution to this problem is to examine the effect size from the original study and generate the range of effect sizes that could reasonably be obtained (due to random sampling) in a replication attempt (i.e., calculate a prediction interval). This package has functions that calculate the prediction interval for the correlation (i.e., r), standardized mean difference (i.e., d-value), and mean.

Density, distribution function, quantile function and random generation for the family of power and reversal power distributions.

Pivot easily by specifying rows, columns, values and split.

For working with the Prevision.io AI model management platform's API <https://prevision.io/>.

This package provides a package for selecting the most relevant features (genes) in the high-dimensional binary classification problems. The discriminative features are identified using analyzing the overlap between the expression values across both classes. The package includes functions for measuring the proportional overlapping score for each gene avoiding the outliers effect. The used measure for the overlap is the one defined in the "Proportional Overlapping Score (POS)" technique for feature selection. A gene mask which represents a gene's classification power can also be produced for each gene (feature). The set size of the selected genes might be set by the user. The minimum set of genes that correctly classify the maximum number of the given tissue samples (observations) can be also produced.

This package provides a comprehensive framework for model fitting and simulation of drug release kinetics, pharmacokinetics (PK), and pharmacodynamics (PD). The package implements widely used mechanistic and empirical models for in vitro drug release, including zero-order, first-order, Higuchi, Korsmeyer-Peppas, Hixson-Crowell, and Weibull models. Pharmacokinetic functionality includes linear and nonlinear functions for one- and two-compartment models for intravenous bolus and oral administration, Michaelis-Menten kinetics, and non-compartmental analysis (NCA). Pharmacodynamic and dose-response modeling is supported through Emax-based models, including stimulatory (sigmoid Emax) and inhibitory (sigmoid Imax) Hill models, four- and five-parameter logistic models, as well as median toxic dose (TD50) and lethal dose (LD50) models. The package is intended to support parameter estimation, simulation, and model comparison in pharmaceutical research, drug development, and pharmacometrics education. For more details, see Gabrielsson & Weiner (2000) <ISBN:9186274929>, Holford & Sheiner (1981) <doi:10.2165/00003088-198106060-00002>, and Manlapaz (2025) <doi:10.32614/CRAN.package.adsoRptionCMF>.

This package provides a multiple testing procedure for testing several groups of hypotheses is implemented. Linear dependency among the hypotheses within the same group is modeled by using hidden Markov Models. It is noted that a smaller p value does not necessarily imply more significance due to the dependency. A typical application is to analyze genome wide association studies datasets, where SNPs from the same chromosome are treated as a group and exhibit strong linear genomic dependency. See Wei Z, Sun W, Wang K, Hakonarson H (2009) <doi:10.1093/bioinformatics/btp476> for more details.

Generation of multiple count, binary, ordinal and normal variables simultaneously given the marginal characteristics and association structure. The details of the method are explained in Demirtas et al. (2012) <DOI:10.1002/sim.5362>.

Phenotype study cohorts in data mapped to the Observational Medical Outcomes Partnership Common Data Model. Diagnostics are run at the database, code list, cohort, and population level to assess whether study cohorts are ready for research.

Estimating Non-Simplified Vine Copulas Using Penalized Splines.

Parametric bootstrap (PB) has been used for three-way ANOVA model with unequal group variances.